Gene AqueK672 (A.queenslandica)

AqueK672

Species: A.queenslandica
Alias: AqueK672
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: TAK1

Sequence

Name Sequence Type Origin Length Description Download
AqueK672.AA Protein None 2385 None Fasta, JSON
AqueK672.kin_dom Protein Kinase Domain None 248 None Fasta, JSON

Protein domain

Protein domains of AqueK672.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK672.AA TKL 58-307 23 3.9e-63 216.07 In-house 1-364 (364) Show / Hide 
Range on Protein: 58-307
Range on HMM: 1-364/364
Sequence Identity: 23% (87 aa)

LKKGSFGSIRHAATLE---------GKDVAIKYFTSRDIKG----------------------------GYNDELTILNALQTHDNIVVLLG--------
. .|.|| . ..             |||||.| | |.. .                                 | . .     |.||| ..|        
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-AGLSP--MTKEPFVVMEFAPY-SLNRVLHGYPRYTYKNDHVMHWARQTALGLEYIHSKR--------ILYRDVKSSNLLLFGNGSH-------------
 . ..|   ..... |||..|  ||  .||         .. ..||...|.|..| ||..        |..|| ||.|.|.. |. .             
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

LKLCDFGISCNIETDA--------------------TYTSGVGTPRYMAPEVIKGT----------------TYDTKCDIFSFAITLWEMLARQIPTIEG
.|.||||.| .....                     |  . .||||.|||||..|.                .|..|||..||.| |||.|.|..|  . 
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDY

LDDNSNIY----AVFYAMAQLEKRPPLL------------VGHPSFVNELLQKCWDQDPRLRPTSTELAEEL
  .   .     . |.  ..  .|||.                |  . .|.|.|||.||. ||. .|. ..|
PYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK672.AA TAK1 52-306 27 1.3e-62 210.26 In-house 1-284 (284) Show / Hide 
Range on Protein: 52-306
Range on HMM: 1-284/284
Sequence Identity: 27% (80 aa)

KPDDEFLKKGSFGSIRHAATLEGKDVAIKYFT------SRDIKGGYNDELTILNALQTHDNIVVLLGAGL-SPMTKEPFVVMEFAPY-SLNRVLHG-YPR
.   .|. ||..|. .  |.  .|..|.| |       .  ..     |.. .     | ||. | |  . .  ..   .|||..   ||  .|||  | 
IQNEHFVGKGTYGVVCK-AKWRNKEIAVKRFEFIKYSSEECEQKNIEREIMQWSRVD-HPNIIKLYG--MYACHRQCQCLVMEYMDCGSLHNFLHGAKPK

YTYKNDHVMHWARQTALGLEYIHSKR---ILYRDVKSSNLLLFGNGSHLKLCDFGISCNIETDATYTSGVGTPRYMAPEV--------------------
  |. .|.| |..| | |. | ||.    .  ||.|  |.||   .  ||.||||  | . .    |.  ||.|.|||||                    
WEYTHAHAMSWMHQCAQGVAYLHSMQPKPQIHRDIKPQNMLLCNKHRTLKICDFGTFCDMHQ--MMTCNRGTCRWMAPEVRELFDFKSNRIIINQPTGFQ

--IKGTTYDTKCDIFSFAITLWEMLARQIPTIEGLDDNSN---IYAVFYAMAQLEKRPPLLV--GHPSFVNELLQKCWDQDPRLRPTSTELAEE
  ... .|. ||||.|..|..||...|. |     |.. |   .|.  .| .. ...| ...    |    .. ..|||..|  ||.. |  . 
KVFRCEKYNMKCDIYSWGIIMWEVISRKHP----YDHIMNPNSAYRIMWAIHNGNRPPMETNRSDCPKRIEQFMKCCWDDNPEKRPSMQECVKY
Kinase AqueK672.AA MLK 52-307 30 1.6e-61 210.74 In-house 1-291 (291) Show / Hide 
Range on Protein: 52-307
Range on HMM: 1-291/291
Sequence Identity: 30% (90 aa)

KPDDEFLKKGSFGSIRHAATLEGKD-----VAIKYFT--------SRDIKGGYNDELTILNALQTHDN----IVVLLGAGLSPMTKEPFVVMEFAPY-SL
    |.. .||||.    ..  .||     ||.| ..        .  ..   . |  .|. |. | |    |....|. |.|  .. ..|||.... ||
IQFHEWIGSGSFGKVWK-GRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILS-HPNNHPCIIQFYGVCLQPP-CHFCIVMEYCEGGSL

NRVLHGYPR------------YTYKNDHVMHWARQTALGLEYIHS-KR--ILYRDVKSSNLLLFG-----NGSHLKLCDFGISCNIETD-ATYTSGVGTP
..|||| .              .|. ||.| || | | |..| || ..  |  || ||.|.|.       .. .|| ||||.|. . .  .. .|  ||.
YNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTY

RYMAPEVI---KGTTYDTKCDIFSFAITLWEMLARQIPTIEGLDDNSNIYAVFYAMAQLEKRPPLLVGHPSFVNELLQKCWDQDPRLRPTSTELAEEL
..||||||   ....|. |||..|... |||||.|..|     ...... |... .|. ..|||.  . |   ..|...||.|||. ||.. .  ..|
AWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYK---QHYDPM-AIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase AqueK672.AA Pkinase 60-307 23 3.7e-52 184.4 Pfam 9-293 (293) Show / Hide 
Range on Protein: 60-307
Range on HMM: 9-293/293
Sequence Identity: 23% (70 aa)

KGSFGSIRHAATLEGKD-VAIKYFTSRDIKGGYND------ELTILNALQTHDNIVVLLGAGLSPMTKEPFVVMEFAPY-----SLNRVLHGYPRYTY--
.||||. ...      . ||.| .  |..| . .       |. |.. |  |.||| |...  .   ... .|||...      .| .....  . ..  
SGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYF

KNDHVMHWARQTALGLEYIHSKRILYRDVKSSNLLLFGNGSHL----KLCDFGISCN--IETDATYTSGVGTPRYMAPEVIK-GTTYDTKCDIFSFAITL
  ... ....|.. ||||.||..|..||.|..|.|.  |  |.    |.||||...   .  .  .|. .|||.|||||||. |. |..|.|..|. ..|
SEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCIL

WEMLARQIPTIEGL---DDNSNIYAVFYAMAQLEKRPPLLVGHP-------------------SFVNELLQKCWDQDPRLRPTSTELAEE--L
.||| .. |   |    |.  . .....   . . . .    ..                   .   ... .|...||  ||| ... .   .
YEMLCGRPPFP-GHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK672.AA S_TKc 52-315 27 3.9e-52 180.44 SMART 1-231 (231) Show / Hide 
Range on Protein: 52-315
Range on HMM: 1-231/231
Sequence Identity: 27% (74 aa)

KPDDEFLKKGSFGSIRHAATLE-GKDVAIKYFTSRDIKGGYNDELTILNALQTHDNIVVLLGAGLSPMTKEPFVVMEFAPY---SLNRVLHGYPR----Y
    . . ||.||. . .   . |. ||||             |. ||     |.||| |...  .   .. ..|||...    .| .... ..|    .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

TYKNDHVMHWARQTALGLEYIHSKRILYRDVKSSNLLLFGNGSHLKLCDFGISCNIETDATYTSGVGTPRYMAPEVIKGTTYDT-KCDIFSFAITLWEML
 .   |. ....|....|||.||..|..||.| .|.||     |.|.||||... .      |. .||| ||||||.    |.. |||. |. ..|.|||
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

ARQIPTIEGLDDNSNIYAVFYAMAQLEKRPPLLVGHPSFVNELLQKCWDQDPRLRPTSTELAE-ELGKICKNFK
... |         .....|  .             |.. . ...||.. ||. |||  |. . |.   |  . 
CGYPPFP-------QMQMMFKKIG-----------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK672.AA TKL-Unique 54-307 28 3.7e-44 153.03 In-house 1-290 (290) Show / Hide 
Range on Protein: 54-307
Range on HMM: 1-290/290
Sequence Identity: 28% (84 aa)

DDEFLKKGSFGSIRHAATLEGKDVAIKYFT----SR-DIKGGYNDELTILNALQTHDNIVVLLGAGLSPMTKEP--FVVMEFAPY-SLNRVLHG------
. . .. |..|.. . ..  |..|||| |     |. ...   ..|..... |. |.||| . |.      ..|  . |||. |  ||. |||       
FWNKIGEGGYGQVYK-GKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

--YPRYTYKNDHVMHWARQTALGLEYIHSKR--ILYRDVKSSNLLLFGNG----SHLKLCDFGISCNIETDATYTSG----------VGTPRYMAPEVIK
   . ..  .  ... |.. |.|..|.|..   |. || ||||.|.  |        |.||||.| .  .. . |..          .|..|.|||||..
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLR

G--TTYDTKCDIFSFAITLWEMLARQI------PTIEGLDDNSNIYAVFYAMAQLEKRPPLLVGHPSFVNELLQKCWDQDPRLRPTSTELAEEL
.  ..|..|.|..||.| |||.. |.|      |  .|.|... . .| |     ..|||.    |    .|.|.||..||  ||. .|  ..|
MNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKP-YQGMDQEQWCEMVHYM--EENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase AqueK672.AA Dicty5 151-311 34 8.8e-38 127.61 In-house 107-260 (260) Show / Hide 
Range on Protein: 151-311
Range on HMM: 107-260/260
Sequence Identity: 34% (55 aa)

MHWARQTALGLEYIHSKRILYRDVKSSNLLLFGNGSHLKLCDFGISCNIETDATYTSGVGTPRYMAPEVIKGTTYDTKCDIFSFAITLWEMLARQIPTIE
.| |   | .....||. |  ||.|| | |.  |    |. |||.| ...    .|  |||. .||.|. .| .|. |||..||.| ||||..|  |   
LHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITEN-WKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWEMFTRKEP---

GLDDNSNIYAVFYAMAQLEKRPPLLVGHPSFVNELLQKCWDQDPRLRPTSTELAEELGKIC
  |.. |.      | .   || .    |.    |  ||| | |..||. .|  . . .| 
-YDNINNWNIPV--MVMKGERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase AqueK672.AA LRRK 94-309 29 3.8e-37 128.96 In-house 107-351 (351) Show / Hide 
Range on Protein: 94-309
Range on HMM: 107-351/351
Sequence Identity: 29% (74 aa)

ELTILNALQTHDNIVVLLGAGLSPMTKEPFVVMEFAPY-SLNRVLHGYPRYTY-----K-NDHVMHW-ARQTALGLEYIHSKR--ILYRDVKSSNLLLFG
|..|.. |. |.||| |.| ...|..     |||.||. .|...|| . ..       . . .. .  | | | |.|| ||..  |..|| || | ||..
EVWIMSHLN-HPNIVSLKGFCIHPLC----MVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWS

N-----------GSHLKLCDFGISC--NIETDATYTSGVGTPRYMAPEVIKGT---TYDTKCDIFSFAITLWEMLARQIPTIEGLDDNSNIYAVFYAMAQ
              . |..|||||    . . .     ||.|..||||.....   .|..| |..||.. ||| | || .  ...|     ....  | |
SPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHD----FFDHMQWMEQ

LEK------RPPLL--VGHPS-----FVNELLQKCWDQDPRLRPTSTELAEELGK
.|.      ||..   .  |       . .|.|.||..||. ||....  . |. 
IEDKIIEGLRPTIPQHY-CPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase AqueK672.AA STE 52-303 23 4.7e-37 128.42 In-house 1-351 (359) Show / Hide 
Range on Protein: 52-303
Range on HMM: 1-351/359
Sequence Identity: 23% (83 aa)

KPDDEFLKKGSFGSIRHAATLE----------------GKDVAIKYFTSRD-------------------IKGGYNDELTILNALQT-HDNIVVLLGAGL
  . |.. ||.||.   |.  .                |. .|||    ..                   ..  .  |. |.. ..  |.|||  .|. .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

-----SPMTKEPFVVMEFAP-YSLNRVLH---GYPR---------YTYKNDHVMHWARQTALG-LEYIHSKRILYRDVKSSNLLLFGNGSHLKLCDFGIS
     .    | ...||. .  ||  ...   | ..          . . . . . .||.  | |.|.||..|  ||.|..| ||       ||||||..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL------VKLCDFGVC

CNIETDAT-----------YTSG------VGTPRYMAPEVIKG------TTYDTKCDIFSFAITLWEMLARQIPTIEGLDDNSNIYAVFY-AMAQ-----
 ... . .           .|..      |||| .||||||..        ||||||| |. .|..||.  . |  .. .     .. |  .|.|     
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

--LEKRPPLLVGH---------------------PSFVNELLQKCWDQDPRLRPTSTEL
  ... || |  |                     |.| .. ..|| . ||. |||...|
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEF-KDFINKCLQKDPNKRPTASQL
Kinase AqueK672.AA TK 60-307 15 2.9e-35 115.13 In-house 9-486 (486) Show / Hide 
Range on Protein: 60-307
Range on HMM: 9-486/486
Sequence Identity: 15% (73 aa)

KGSFG---SIRHA--------------------------ATLEGKDVAIKYFT--SRDIKGGYND--------------ELTILNALQT----HDNIVVL
.| ||    .. .                           . .  .||.|  .  . . .    |              |. ..  ..     |.||| |
EGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNIVRL

LGAGLSPMT----------KEPFVVMEFAPY-----SLNRVLHGYPRY-------------------------------TYKNDHVMH------------
.|. . . .          . . .|||..|.     ||   |.  ...                               ...|..  .            
YGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPC-PEEQDYDDDLIKD

-------------------------------WARQTALGLEYIHSK------RILYRDVKSSNLLLFGNGS----------HLKLCDFGISCN-------
                               ...| | |.||.|||      ..  ||.   | |.. |.           . |..||| | .       
HPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLAR

---IETDATYTSGVGTPR-------------------------YMAPEVIKGTT---------YDTKCDIFSFAITLWEMLARQ-IPTIEGLDDNSNIY-
    ..| . .|. ||.|                         .||||.... .         . || |..|| ...||.. .   |  .|....  .  
DIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKD

---AVFYAMAQLE--------------KRPPLLVGHP--------------SFVNELLQKCWDQDPRLRPTSTELAEEL
   . .. . . .               |.|  .. |               .. .|.|.||. ||. ||| ..| |.|
GDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK672.AA HH498 158-307 32 5.4e-33 101.63 In-house 131-284 (284) Show / Hide 
Range on Protein: 158-307
Range on HMM: 131-284/284
Sequence Identity: 32% (52 aa)

ALGLEYIHS---KRILYRDVKSSNLLLFGNGSHLKLCDFGIS---CNIETDATYTSGVGTPRYMAPEVIK-GTTYDTKCDIFSFAITLWEMLARQIPTIE
| | .| |.   . |  ||  | | |.  .| | .  |||.|   | .. | . |.  | .|.||||| . .. |. | |.||.|. .|||. | .|   
AHGMNYLHNSLKHPIIHRDLNSHNILIHEDG-HAVVADFGESRFVCDMH-DDNMTKQPGNLRWMAPEVFSQCQKYSIKVDVFSYAMCIWEMHTREVP---

GLDDNSNIYAVFYAMAQLEKRPPLLVG----HPSFVNELLQKCWDQDPRLRPTSTELAEEL
   .   . | .  ||  . |||.        |     |.| ||.. |  ||.  .    |
-FHHYKPAAAAA-EMAYHHIRPPIPQTPTAQIPHHWSNLIQMCWHPCPENRPDFDQIVTIL
Kinase AqueK672.AA STE-Unique 154-309 22 1.8e-29 101.51 In-house 409-616 (616) Show / Hide 
Range on Protein: 154-309
Range on HMM: 409-616/616
Sequence Identity: 22% (48 aa)

ARQTALGLEYIHSKR--ILYRDVKSSNLLLFGNG----SHLKLCDFGISCNIETD---------------------------------------ATYTSG
..| ..||||.||..  |. ||.|..| ..   |    .. |.||||..     |                                        | ...
TYQILEGLEYLHSQHNPIIHRDLKPHNIFCMQDGKGRVCKVKICDFGHATCCQPDHFEKDNNSKNSNTWININNNSSTNSTAQQTPMWDLNINNYTMKYC

VGTPRYMAPEVIKGT-----TYDTKCDIFSFAITLWEMLARQIPTIEGLDDNSNIYAVFYAMAQLEKRPP-------LLVGHPSFVNELLQKCWDQDPRL
.||| ||.|||| .       |||| ||.|..... .|.    |  .     ... | ..    . . ||        .   | .. ....|| ...|  
CGTPCYMCPEVINCRNQINNPYDTKVDIWSLGCMCFHMCCGCPPWHQ----RYHMQAYIEMCIHIHCQPPQCPIENIPPKCQPEQQ-QFIEKCLERNPHH

RPTSTELAEELGK
||.  .|.. . .
RPSAHQLLHHFWL
Kinase AqueK672.AA TyrKc 55-307 25 1.8e-22 81.91 SMART 1-280 (280) Show / Hide 
Range on Protein: 55-307
Range on HMM: 1-280/280
Sequence Identity: 25% (73 aa)

DEFLKK---GSFGSIRHAATLEGKDVAIKYFTSRDIKGGYNDELTILNAL-QTHDNIVVLLGAGLSP-----MTKEPFVVMEFAPY-SLNRVLHGYPRYT
 ...||   | || ....      .||.|   .   .    .|. |.  |   |.||| |.|. ...       . ...|||..|. .|.  |. . .  
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK-

YKNDHVMHWARQTALGLEYIHSKRILYRDVKSSNLLLFGNGSHLKLCDFGISCNIETD-------ATYTSGV--GTP-----RYMAPEVIKGTTYDTKCD
 ....  ... | | | ||.|||..  ||    | |.  |. . | .||| | .|. |        .|..    |.      | ||||.|.  .. || |
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSD

IFSFAITLWEMLAR-QIPTIE---GLDDNSNIYAVFYAMAQLEKRPPLLV-------GHPSFVNELLQKCWDQDPRLRPTSTELAEEL
..|| ...||.. . | |  .      . ||. .. | ..    ..|  .        ..   . . ..||. ||  ||| .|. |..
VWSFGVCMWEIFTYGQQPYPGMIQQ--MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK672.AA Pkinase_Tyr 104-242 30 1.5e-21 73.65 Pfam 63-208 (270) Show / Hide 
Range on Protein: 104-242
Range on HMM: 63-208/270
Sequence Identity: 30% (46 aa)

HDNIVVLLGAGL---SPMTKEPFVVMEFAPY-SLNRVLHGY--PRYTYKNDHVMHWARQTALGLEYIHSKRILYRDVKSSNLLLFGNGSHLKLCDFGISC
|.||| |.|. .    |   ....|||..|. .|   |.    ..   .  .  ....| | |.|| .||..  ||.   | |.  |. . | |||| . 
HPNIVRLYGVCTDQGEPN--QIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENN-VVKICDFGLAR

NIETDATY-TSGVGTP---RYMAPEVIKGTTYDTKCDIFSFAITLWEML
 |. | .| ... |..   . ||||.|.   . || |. || ...||..
DIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIF
Kinase AqueK672.AA Pkinase_Tyr 279-307 41 3.4e-05 18.2 Pfam 242-270 (270) Show / Hide 
Range on Protein: 279-307
Range on HMM: 242-270/270
Sequence Identity: 41% (12 aa)

PSFVNELLQKCWDQDPRLRPTSTELAEEL
|  . .|...||..||  ||| .|. |.|
PDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK672.AA Dicty5 74-128 33 0.108494 1.59 In-house 22-80 (260) Show / Hide 
Range on Protein: 74-128
Range on HMM: 22-80/260
Sequence Identity: 33% (20 aa)

GKDVAIKYFTSRD-IKGGYND---ELTILNALQ-THDNIVVLLGAGLSPMTKEPFVVMEF
|.||||| . .   .    |.   | ||. . |  |.|..  .||.    .| || | |.
GMDVAIKVYSQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAHQY-NDKYPFHVTEY
UBCc AqueK672.AA UBCc 1165-1309 30 1.6e-28 102.04 SMART 1-144 (144) Show / Hide 
Range on Protein: 1165-1309
Range on HMM: 1-144/144
Sequence Identity: 30% (46 aa)

RRLMKEATELREPFPHYYTQPMEDNLFEWHFTIQGPPGTDYEGGRYHGHIMISPEYPMKPPSVVFLTP--NGRFK-LNLEICMCGLE-TWQSYWGISTVL
.||||| .|...  | .... ..|||..||.||.|||.| |||| .. .. . ..||.|||.| |.|.  . ...  | |||.  |. .| . | |..||
KRLMKELKEWQKDPPPGFHAFPVDNLMKWHCTITGPPDTPYEGGVFKLTMWFPEDYPFKPPKVRFITKIWHPNIYPSNGEICLDILHEHWSPAWTIRQVL

LELIDMMATDDDRSTFGSLDCTPEERRQLATRSLEWVCPSCGVANRTAL
|... |..   . .     |  .. |.     . |. .  .  . ..| 
LSIQSMLNE-PNPDDPLNVDAAQMWRH----NREEYKKKVREWTKKYAE
UQ_con AqueK672.AA UQ_con 1166-1269 32 1.5e-24 88.25 Pfam 1-130 (161) Show / Hide 
Range on Protein: 1166-1269
Range on HMM: 1-130/161
Sequence Identity: 32% (44 aa)

RLMKEATEL---REPFPHYYTQPMED----NLFEWHFTIQGPPGTDYEGGRYHGHIMISPEYPMKPPSVVFLT---------PNGRFKLNLEICMCGLE-
||.||  ||   ..| | ..  | .|    |||.|| ||.||..| |||| .. .. . ..||.|||.| |.|         ||||       |   |  
RLQKEYKELDWQKDPPPGFSAFPVDDPDPNNLFHWHCTIRGPEDTPYEGGVFKLDMEFPEDYPFKPPKVKFTTKIWHPNVYSPNGRI------CLDILHP

---------T-----WQSYWGISTVLLELIDMM-AT
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GDDPMYEADEHDHEKWSPAWTIRQVLLSIQSLLMCE
SH2 AqueK672.AA SH2 1499-1582 43 3.2e-33 117.6 SMART 1-87 (87) Show / Hide 
Range on Protein: 1499-1582
Range on HMM: 1-87/87
Sequence Identity: 43% (38 aa)

MPWFHGKMSRQEAENVLNP--TKDGLFLVRESSFFAGDYILCVCYKGKVGHCRITRTDKNLVTLNG--KEYFENLISLVEHHQKDAGG
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QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
SH2 AqueK672.AA SH2 1501-1576 48 6e-33 98.55 Pfam 1-81 (81) Show / Hide 
Range on Protein: 1501-1576
Range on HMM: 1-81/81
Sequence Identity: 48% (39 aa)

WFHGKMSRQEAENVLNP--TKDGLFLVRESSFFAGDYILCVCYKG---KVGHCRITRTDKNLVTLNGKEYFENLISLVEHH
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WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY