AqueK674

Species: A.queenslandica
Alias: AqueK674
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: TAK1

Sequence

Name Sequence Type Origin Length Description Download
AqueK674.AA Protein None 523 None Fasta, JSON
AqueK674.kin_dom Protein Kinase Domain None 344 None Fasta, JSON

Protein domain

Protein domains of AqueK674.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK674.AA TAK1 28-281 31 8.7e-74 248.63 In-house 1-284 (284) Show / Hide
Range on Protein: 28-281
Range on HMM: 1-284/284
Sequence Identity: 31% (90 aa)

KPDQKFVEQGAYGRVCRATHEGKDVAVKYFK------SVEEKRGYKQELVFLKCLQEHENIVILYGTGSSPKTKEPYIVMEFAPY-SLERVLHGSHPHRY
.   .||  |.|| ||.|.  .|..||| |.      . .|.   . |.. .  .  |.||. |||. .... .  . |||..   ||  .|||. |.  
IQNEHFVGKGTYGVVCKAKWRNKEIAVKRFEFIKYSSEECEQKNIEREIMQWS-RVDHPNIIKLYGMYACHRQCQ-CLVMEYMDCGSLHNFLHGAKPK-W

RYGVDHVMHWSRQTAVGLKHIHSKR---ILHRDIKSSNLLLFGNGSRLKLCDFGTCRNLETNLLYTASIGTVRYMAPEV---------------------
 | ..|.| | .| | |.   ||.    . |||||  |.||   .  ||.|||||   . ..   |   || |.|||||                     
EYTHAHAMSWMHQCAQGVAYLHSMQPKPQIHRDIKPQNMLLCNKHRTLKICDFGTFCDMHQMM--TCNRGTCRWMAPEVRELFDFKSNRIIINQPTGFQK

-IKGDPYTTKCDIFSFAITLWEMLARQVPTIESVSANS-YAILYQMVQGKRPPLLVG---HPPFVNELLEKCWDQDPAVRLTSNDLVDKF
 ... .|. ||||.|..|..||...|. |  .  . || |.|..   .|.|||..      |.   .. ..|||..|. | .. . | |.
VFRCEKYNMKCDIYSWGIIMWEVISRKHPYDHIMNPNSAYRIMWAIHNGNRPPMETNRSDCPKRIEQFMKCCWDDNPEKRPSMQECV-KY

Kinase AqueK674.AA TKL 34-281 22 9.4e-70 238.04 In-house 1-364 (364) Show / Hide
Range on Protein: 34-281
Range on HMM: 1-364/364
Sequence Identity: 22% (84 aa)

VEQGAYGRVCRATHEG----------KDVAVKYFKSVE-EKRGY-------------------------KQELVFLKCLQE--HENIVILYGTGSSPK--
. .|..| |..... |          |||||| ||| .  ..                           ..| . ....    |.||| ..|   .|.  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

---------TKEPYIVMEFAPY-SLERVLHGSHPHRYRYGVDHVMHWSRQTAVGLKHIHSKR--------ILHRDIKSSNLLLFGNGS------------
         .....||||..|  ||. .||           .. ..|....| |. . ||..        |.|||.||.|.|.. |.             
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

-RLKLCDFGTCRNLETNLLYTAS--------------------IGTVRYMAPEVIKGD----------------PYTTKCDIFSFAITLWEMLARQVPTI
 ..|.||||..|.....   ...                    .|| |.|||||..|.                .|..|||..||.| |||.|.|..|  
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYY

ESVSANSY------AILYQMVQ-GKRPPLL------------VGHPPFVNELLEKCWDQDPAVRLTSNDLVDKF
.  .   .      ..... .. |.|||.                || . .|...|||.||  |.. .......
DYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase AqueK674.AA MLK 28-281 30 4.8e-62 212.44 In-house 1-291 (291) Show / Hide
Range on Protein: 28-281
Range on HMM: 1-291/291
Sequence Identity: 30% (90 aa)

KPDQKFVEQGAYGRVCRATHEGKD-----VAVKYFK--------SVEEKRGYKQELVFLKCLQEHEN----IVILYGTGSSPKTKEPYIVMEFAPY-SLE
   ....  |..| |....  .||     |||| ..        . .|..  ..|   |. |. |.|    |...||. ..|  .. .||||.... || 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILS-HPNNHPCIIQFYGVCLQPP-CHFCIVMEYCEGGSLY

RVLHGSHPHRY----------RYGVDHVMHWSRQTAVGLKHIHS-KR--ILHRDIKSSNLLLFG-----NGSRLKLCDFGTCRNLETN-LLYTASIGTVR
.||||  .. .          .| .||.| |. | | |.   || ..  | |||.||.|.|.       ..  || ||||| | . ..    .  .||..
NVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYA

YMAPEVI---KGDPYTTKCDIFSFAITLWEMLARQVPTIESVSANSYAILYQMVQGK-RPPLLVGHPPFVNELLEKCWDQDPAVRLTSNDLVDKF
.||||||   ....|. |||..|... |||||.|.||       .. ||...... . |||.  . |.  ..|...||.|||. | ..   | ..
WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYK--QHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL

Kinase AqueK674.AA S_TKc 28-290 27 4.2e-58 200.26 SMART 1-231 (231) Show / Hide
Range on Protein: 28-290
Range on HMM: 1-231/231
Sequence Identity: 27% (74 aa)

KPDQKFVEQGAYGRVCRATHEG--KDVAVKYFKSVEEKRGYKQELVFLKCLQEHENIVILYGTGSSPKTKEPYIVMEFAPY---SLERVLHGSHPHRYR-
    . . .||.|.|....| .  . ||.|  |     .  ..|.  ||    |.||| ||..  .   .. |.|||...    .| ....   .|..| 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-YGVDHVMHWSRQTAVGLKHIHSKRILHRDIKSSNLLLFGNGSRLKLCDFGTCRNLETNLLYTASIGTVRYMAPEVIKGDPYTT-KCDIFSFAITLWEML
 .   |. .. .|.. .|...||..|.|||.| .|.||     ..|.|||| .| |      |  .||  ||||||.   .|.. |||. |. ..|.|||
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

ARQVPTIESVSANSYAILYQMVQGKRPPLLVGHPPFVNELLEKCWDQDPAVRLTSNDLVDKFNKICEHFTF
... |         .. .....           |.. . ...||.. ||. |.|  ..     .|  |  |
CGYPPFP------QMQMMFKKIG---------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase AqueK674.AA Pkinase 36-288 27 2.7e-55 194.81 Pfam 9-293 (293) Show / Hide
Range on Protein: 36-288
Range on HMM: 9-293/293
Sequence Identity: 27% (82 aa)

QGAYGRVCRATHEGKD--VAVKYFKSVEEKRGYKQ------ELVFLKCLQEHENIVILYGTGSSPKTKEPYIVMEFAPY-----SLERVLH-GSHPHRYR
.|..|.|....| |    |||| .| ..|| . .|      |.  .| |  |.||| ||..  .   ...|.|||...      .| ....  .|   | 
SGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFY-

YGVDHVMHWSRQTAVGLKHIHSKRILHRDIKSSNLLLFGNGSR---LKLCDFGTCRN--LETNLLYTASIGTVRYMAPEVIK-GDPYTTKCDIFSFAITL
   ... .. .|.. ||...||..|.|||.|..|.|.  ||     .|.|||| ..   .  |  .|   || .|||||||. | .|..|.|..|. ..|
FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCIL

WEMLARQVPTIES-VSANSYAILYQMVQGKRPPLLVGHP-----------------------PFVNELLEKCWDQDPAVRLTSNDLVDKFNKICEH--F
.||| .. |  ..  . | .  .. ... ..|||    |                       .   .....|...||. |.|       .  |..|  |
YEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-------AEQILQHPWF

Kinase AqueK674.AA TKL-Unique 30-271 27 2.6e-49 170.15 In-house 1-280 (290) Show / Hide
Range on Protein: 30-271
Range on HMM: 1-280/290
Sequence Identity: 27% (77 aa)

DQKFVEQGAYGRVCRATHEGKDVAVKYFK----SVEEKRG-YKQELVFLKCLQEHENIVILYGTGS--SPKTKEPYIVMEFAPY-SLERVLH------GS
. . . .|.||.|..... |..||.| |.    |  |..   . |.  .|.|. |.||| ..|.     .. .. .||||. |  ||  |||        
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

HPHRYRYGVDHVMHWSRQTAVGLKHIHSKR--ILHRDIKSSNLLLFGNG----SRLKLCDFGTCRNLETNLLYTAS----------IGTVRYMAPEVIKG
 .  .      ...  .. | |. ..|..   |.|||.||||.|.  |      . |.||||..... ...  |..          .|. |.|||||...
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

--DPYTTKCDIFSFAITLWEMLARQV------PTIESVSANSYA-ILYQMVQGKRPPLLVGHPPFVNELLEKCWDQDPAVR
  . |..|.|..||.| |||.. |..      |  .... .... .. .|  ..|||.    |.   .|...||..||  |
NFCQYSEKSDVYSFGIVLWEIATRKITKTYKKP-YQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQR

Kinase AqueK674.AA TK 36-281 15 1.2e-40 133.47 In-house 9-486 (486) Show / Hide
Range on Protein: 36-281
Range on HMM: 9-486/486
Sequence Identity: 15% (72 aa)

QGAYG---RVCRATHEGK---------------------------DVAVKYFK--SVEEKRGYKQ--------------ELVFLKCLQE----HENIVIL
.|..|   .|.... .|.                           .||||  |  . ....  ..              |.  .| ...    |.||| |
EGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNIVRL

YGTGSSPKT----------KEPYIVMEFAPY-----SLERVLHGSHPHRYR-------------------------------------------------
||  . ...          . ..||||..|.     ||   |. ..|..                                                   
YGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKDH

-----------------------YGVDHVMHWSRQTAVGLKHIHSK------RILHRDIKSSNLLLFGNGSR----------LKLCDFG--------TCR
                         . . . ...| | |. ..|||      .. |||.   | |.. |. .           |..|||         .|
PPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLAR

NLETNLLYTASI------------------------GT---VRYMAPEVIKGDP---------YTTKCDIFSFAITLWEMLARQVPTIESVSAN------
 .. .  |...                         |.   .|.||||....           .||| |..|| ...||.. .   .      |      
DIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKD

--SYAILYQMVQG--------------KRPPLLVGHP--------------PFVNELLEKCWDQDPAVRLTSNDLVDKF
     .. . ..|               |.|  .. |              ... .|. .||. ||. | |  .|....
GDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase AqueK674.AA CMGC 36-219 19 2.1e-39 126.54 In-house 9-329 (513) Show / Hide
Range on Protein: 36-219
Range on HMM: 9-329/513
Sequence Identity: 19% (62 aa)

QGAYGRVCRATH----------------EGKDVAVKYFKSVEEKRGYKQ--------------ELVFLKCLQ----------------EHENIVILYGTG
.|.|| |.....                 .. ||.| .|... .   ..              |. .||.|.                 |.||| ||   
EGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNIVKLYDIF

SSPKTKEP---------------YIVMEFAPYSLERVLH-------------GSHPH------------RYRYGVDHVMHWSRQTAVGLK--HIHSKR--
 ..... .               |.|.|. ...| ....              |. |               . . |.  ...|   |||  ..||..  
YHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKYCHSHWGN

ILHRDIKSSNLLLFGNG-------------------SRLKLCDFGTCRNLETNL----------------------LYTASIGTVRYMAPEVIKGDP---
|.|||.| .|.|.  |.                    |||.|||| .| ....                        ||  . |  | |||.. |..   
IIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLGWKHYT

-------YTTKCDIFSFAITLWEML
       |||..|. |..  . ||.
NHNYSMHYTTPIDMWSVGCIFAEMY

Kinase AqueK674.AA STE 132-277 28 2.4e-38 133.06 In-house 158-351 (359) Show / Hide
Range on Protein: 132-277
Range on HMM: 158-351/359
Sequence Identity: 28% (58 aa)

RQTAVG-LKHIHSKRILHRDIKSSNLLLFGNGSRLKLCDFGTCRNLETNLL-----------------YTASIGTVRYMAPEVIKG------DPYTTKCD
||.  | |...||..| |||||..| ||       ||||||.| .|. ..                   .  .||  .||||||..      ..|.||||
RQILKGLLYYLHSHHIIHRDIKPANILL------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCD

IFSFAITLWEMLARQVPTIE-SVSANSYAIL--YQMVQ---------GKRPPLLVGHP-------------------PFVNELLEKCWDQDPAVRLTSND
| |. .|..||.  ..|  . .   . ..|.  | |.|         |. |||                        |  .. ..|| . ||  | |...
IWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ

L
|
L

Kinase AqueK674.AA Dicty5 135-285 36 8.3e-38 127.71 In-house 114-260 (260) Show / Hide
Range on Protein: 135-285
Range on HMM: 114-260/260
Sequence Identity: 36% (55 aa)

AVGLKHIHSKRILHRDIKSSNLLLFGNGSRLKLCDFGTCRNLETNLLYTASIGTVRYMAPEVIKGDPYTTKCDIFSFAITLWEMLARQVPTIESVSANSY
| ...|.||. | |||.|| | |.  |    |. |||| |. .  . .|  .||  .||.|. .| ||. |||..||.| ||||..|  |  .    |. 
AQSMRHLHSMNIIHRDLKSMNFLITEN-WKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWEMFTRKEPYDN---INNW

AILYQMVQGKRPPLLVGHPPFVNELLEKCWDQDPAVRLTSNDLVDKFNKIC
 |      | || .    |     | .||| | |  | .    .. |..| 
NIPVMVMKGERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII

Kinase AqueK674.AA CAMK 33-210 17 5.9e-35 109.54 In-house 1-319 (425) Show / Hide
Range on Protein: 33-210
Range on HMM: 1-319/425
Sequence Identity: 17% (55 aa)

FVEQGAYGRVCRATHEGKD--------------VAVKYFK------------------------------SVEEKRGYKQELVFLKCLQE------HENI
   .|..| | ...|                  ||.|  .                              . . ..  ..|.  .| ||.      |.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VILYGTGSSPK-----------------TKEPYIVM---EFAPYS------LERVLHGSHPH----------RYRYGVDHVMHWSRQTAVGLKHIHSKRI
. || .  .|.                 .|. |.||   |...        ....   ...           | |.  . . .. || . .....||. |
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

LHRDIKSSNLLLFGNG----------------SRLKLCDFGTCRNLET------------------------NLLYTASIGTVRYMA-PEVIKG------
 |||.|  |.||  |.                  .|..|||  . ..                         . ... . ||  ||| |||..|      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------DPYTTKCDIFS
        ..|. |||. |
QNATDEEKPYYGPKCDMWS

TyrKc AqueK674.AA TyrKc 25-281 25 2.2e-34 121.5 SMART 1-280 (280) Show / Hide
Range on Protein: 25-281
Range on HMM: 1-280/280
Sequence Identity: 25% (74 aa)

LEFKPDQKFVEQGAYGRVCRATHEGKDVAVKYFKSVEEKRGYKQELVFLKCL-QEHENIVILYGTGSSPKT-----KEPYIVMEFAPY-SLERVLHGSHP
....   |    ||.|.|...|    .||||  |.   ..   .|.  .. |  .|.||| |||  ....      . ..||||..|. .|   |. ..|
ITLG---KKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

HRYRYGVDHVMHWSRQTAVGLKHIHSKRILHRDIKSSNLLLFGNGSRLKLCDFGTCRNLETN-------LLYTA-----SI--GTVRYMAPEVIKGDPYT
.     ...  ... | | |  ..|||.. |||.   | |.  |. . | .||| .|...           |..     .     .| ||||.|.   .|
K---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

TKCDIFSFAITLWEMLAR-QVPTIESVS--ANSYAILYQMVQGKRPPLLVG--------HPPFVNELLEKCWDQDPAVRLTSNDLVDKF
|| |..|| ...||.. . | |  . .    . . .. .  ||.|.|             |. . .. ..||. ||. | | ......|
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase AqueK674.AA Ciliate-E2-Unclassified 36-224 21 4.9e-30 101.4 In-house 9-269 (352) Show / Hide
Range on Protein: 36-224
Range on HMM: 9-269/352
Sequence Identity: 21% (56 aa)

QGAYGRVCRATHEG-------------KDVAVKYFKSVEEKRGYKQELVFLK--------------CLQEHENIVILYGTGSSPKTKEPYIVMEFAPYSL
||..| |... |.              .....|. ....     ... .. |               |. | ...|..      ... .|||||....  
QGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGD

ERVLHGSHPH--------------RYRYGVDHVM-----HWSRQTAVGLKHIHSK-RILHRDIKSSNLLLFGNGS--RLKLCDFGTCRNLETN-------
 .  . . ..              | .    ..      .. .|  .||...|.|  |.||||| .|.|.  ||.  ..|..||| ......|       
LWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQ

---------LLYTASIGTVRYM----APEVIKGDPYT----TKCDIFSFAITLWEMLARQVP
          ...  .|| .||    ||||..|  |      ||||.|. . | |||  . |
QQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYP

Kinase AqueK674.AA Pkinase_Tyr 36-219 29 2.3e-21 72.97 Pfam 9-208 (270) Show / Hide
Range on Protein: 36-219
Range on HMM: 9-208/270
Sequence Identity: 29% (59 aa)

QGAYGRVCRATHE------GKDVAVKYF--KSVEE---KRGYKQELVFLKCLQEHENIVILYGTGS---SPKTKEPYIVMEFAPY-SLERVLHGSHPHRY
.||.|.|...|        . .||||    .. .|   ..   .|.  .| |  |.||| |||  .    |.  ..|||||..|. .|   |.   . . 
EGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN--QIYIVMEYMPHGDLLDYLRKHREDKQ

RYGVDHVMHWSRQTAVGLKHIHSKRILHRDIKSSNLLLFGNGSRLKLCDFGTCRNL---ETN-LLYTASIGTVRYMAPEVIKGDPYTTKCDIFSFAITLW
.  . .  ....| | |. . .||.. |||.   | |.  |.   | |||| .| .   ..     . .   .. ||||.|.   .||| |. || ...|
PLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENN-VVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMW

EML
|..
EIF

Kinase AqueK674.AA STE 28-103 18 5.6e-08 24.39 In-house 1-118 (359) Show / Hide
Range on Protein: 28-103
Range on HMM: 1-118/359
Sequence Identity: 18% (22 aa)

KPDQKFVEQGAYGRVCRATHE-----------------GKDVAVKYFK-------------------SVEEKRGYKQELVFLKCLQE-HENIVILYGTGS
  ..... .||.| |..| .                  |. .|.|  .                     ||.  ...|. ..|...  |.|||  ||.  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

SPKTK-----EPYIVMEF
   ..     | .|.||.
KEGHNHKNDDELWICMEY

Kinase AqueK674.AA Pkinase_Tyr 253-281 27 0.025336 8.49 Pfam 242-270 (270) Show / Hide
Range on Protein: 253-281
Range on HMM: 242-270/270
Sequence Identity: 27% (8 aa)

PPFVNELLEKCWDQDPAVRLTSNDLVDKF
|. . .|. .||..||. | |  ... ..
PDEIYDLMKQCWHYDPEDRPTFSEIHEQL

Kinase AqueK674.AA Dicty5 31-57 37 0.157984 1.02 In-house 4-30 (260) Show / Hide
Range on Protein: 31-57
Range on HMM: 4-30/260
Sequence Identity: 37% (10 aa)

QKFVEQGAYGRVCRATHEGKDVAVKYF
 ...  || |||      |.|||.| .
HDWIASGASGRVYNGIYKGMDVAIKVY