Gene AqueK676 (A.queenslandica)

AqueK676

Species: A.queenslandica
Alias: AqueK676
External Links:
Annotation:

Classification

Group: TKL
Family: RAF
Subfamily: KSR

Sequence

Name Sequence Type Origin Length Description Download
AqueK676.AA Protein None 1246 None Fasta, JSON
AqueK676.kin_dom Protein Kinase Domain None 303 None Fasta, JSON

Protein domain

Protein domains of AqueK676.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
C1_1 AqueK676.AA C1_1 549-598 25 2.6e-10 41.48 Pfam 1-55 (55) Show / Hide 
Range on Protein: 549-598
Range on HMM: 1-55/55
Sequence Identity: 25% (14 aa)

HRFINH-IFFGVQECDYCKKSM----VVSGYRCRYCKSKFHKNCSKLAPPICGLP
|... |  | .   |..|....       |..|. |. ..|. |....|| ||. 
HHWVHHWNFKQPTFCCHCGEFCWGWLGHQGWKCQWCHYNCHHRCHMKVPPECGCN
C1 AqueK676.AA C1 547-595 23 2.4e-08 34.99 SMART 1-61 (61) Show / Hide 
Range on Protein: 547-595
Range on HMM: 1-61/61
Sequence Identity: 23% (15 aa)

IDHRFINHIFFGVQECDYCKKSMVVS--------GYRCRYCKSKFHKNCSKLAPP-------IC
..... ..   .   |..|.|..  .        ||||. || |.||.|.. .|.        |
HHWHWWRF---KPTYCCHCRKMIWGMFKQHWKMQGYRCSWCKYKCHKKCHDKVPQQSHQDGWMC
C1_3 AqueK676.AA C1_3 560-588 23 6.9e-05 13.93 Pfam 1-30 (30) Show / Hide 
Range on Protein: 560-588
Range on HMM: 1-30/30
Sequence Identity: 23% (7 aa)

QECDYCKKSMVV-SGYRCRYCKSKFHKNCS
 .|. |...    ..|.|  |   .|..| 
FTCNCCGLPIYRDPFYHCMQCDFMLHEDCA
Kinase AqueK676.AA RAF 939-1216 36 2.1e-96 326.59 In-house 1-275 (275) Show / Hide 
Range on Protein: 939-1216
Range on HMM: 1-275/275
Sequence Identity: 36% (104 aa)

LKLLEKLGSGPVAEVYKGYWHGEVAVKRFVLPNATP-KQINKFREEVAVLKKIRHENLALFMGVCLTT--PNLAIITSYCKGYTLYKLLHYWSE-AFSLE
....|. |.|    ||.| |||.||||       || .|.. |. ||...||.||||..|||| |     |..||.|. ||| |||. .|   .  | . 
VQIGERIGQGRFGTVYRGHWHGDVAVKTLNMKYPTPEHQLQAFKNEVMMYKKTRHENIVLFMGYCMKPDNPHYAIVTQWCKGSTLYHHIHVQKTEKFDMN

RLANIGRQIAQAMGYLHARGIIHKGLNTKNIFLEKRDQKEKVIITDMGLSSLSSLLYDNTTSKGGVVTFPRAQLYSLAPEIIRKISP-TPVVQIDQEPYS
..  | .||.|.|.||||..|||. | .|||||.    . .|.||| ||.... ...  . ...  .  |.  .  .|||.||. .| ... | |. |.|
WTIQIAQQICQGMDYLHAKNIIHRDLKSKNIFLH---NGKVVVITDFGLFTVKRCRWCKRRKQQ--LCQPHGWICWMAPEVIRMMRPDWDEYQCDCNPFS

YNYATDVYAFGTILYELITKRFPFSTDSLGFAYEFEVVIFLVGHGHRQPF----KGETPKKLKDIVWECWSHQPQDRPPFSDLQERL
 .  .|||||||..|||.. ..|.. ..       | .|. |. | ....       .||..|... |||| ||..|| |... ...
FQ--SDVYAFGTVWYELMAGEWPYQHIQ-----WHEQIIWMVCRGYLRMDRSKARVQCPKEMKELLMECWSYQPEERPSFQQIMKMI
Kinase AqueK676.AA KSR 939-1216 40 9.6e-90 304.45 In-house 1-272 (272) Show / Hide 
Range on Protein: 939-1216
Range on HMM: 1-272/272
Sequence Identity: 40% (115 aa)

LKLLEKLGSGPVAEVYKGYWHGEVAVKRFVLP--NATPKQINKFREEVAVLKKIRHENLALFMGVCLTTPNLAIITSYCKG-YTLYKLLHYWSEAFSLER
||..|  | |    |..| ||||||.|           . ...|..||. .|..||||..|||| |   |.|||..| |||  ||| ..|   | . . |
LKYGECIGQGRFGKVHRGHWHGEVAIKLYYMDHIHDEHHDLEDFKDEVMMYKNTRHENIVLFMGACMNPPHLAIVMSLCKGSQTLYHHIHVRREKLDMNR

LANIGRQIAQAMGYLHARGIIHKGLNTKNIFLEKRDQKEKVIITDMGLSSLSSLLYDNTTSKGGVVTFPRAQLYSLAPEIIRKISP-TPVVQIDQEPYSY
   | .||.|.||||||.||||| | .||||.|    | ||.||| ||.| . ||.  .  . .  . |.  |  ||||.||. .| ..  | .  |.| 
TMQIAQQICQGMGYLHAKGIIHKDLKSKNIFYEN---KGKVVITDFGLFSITRLLHCCQ--REDHLCIPHGWLCYLAPELIRAMRPNYDEYQCMCLPFSH

NYATDVYAFGTILYELITKRFPFSTDSLGFAYEFEVVIFLVGHG--HRQPFKG-ETPKKLKDIVWECWSHQPQDRPPFSDLQERL
.  .||||||||.||.|. ..|| .         | .|. .. |   ||..      . .|.|  .|||  ||.|| |.|.   |
H--SDVYAFGTIWYEMICGEWPFKYQCA------ESIIWQMCQGEGMRQVLRNVQCGREMKEILMMCWSYEPQERPTFQDIMKML
Kinase AqueK676.AA RAF 939-1218 32 3.8e-75 243.05 In-house 1-282 (282) Show / Hide 
Range on Protein: 939-1218
Range on HMM: 1-282/282
Sequence Identity: 32% (97 aa)

LKLLEKLGSGPVAEVYKGYWHGEVAVKRFVLPNATPKQINK---FREEVAVLKKIRHENLALFMGVCLTTPN---LAIITSYCKGYTLYKLLHYWSE--A
... .. |||    ||.| |||.||||.  . . ||.|.     |..||||.|| || | .|||| . . |.   .||.| .| . .||. .|       
VMVMTRIGSGSFGTVYRGHWHGDVAVKMLNVNDPTPEQMQADVFFKNEVAVYKKTRHCNILLFMG-YMSKPQTNTYAIVTQWCEHSSLYHHIHVQETREK

FSLERLANIGRQIAQAMGYLHARGIIHKGLNTKNIFLEKRDQKEKVIITDMGLSSLSSLLYDNTTSKGGVVTFPRAQLYSLAPEIIR---KISPTPVVQI
| .  | .|.||..|.| ||||. |||  | ..||||   .   .| |.| ||  . ..    .   .  .  |      .|||.||         |.  
FDMHWLIDISRQVCQGMDYLHAKNIIHRDLKSNNIFL---HEDMTVKIGDFGLMTVKTR---WSPRGNQQFEQPTHWILWMAPEVIRNLMIDWRGDVLMQ

DQEPYSYNYATDVYAFGTILYELITKRFPFSTDSLGFAYEFEVVIFLVGHGHRQP----FKGETPKKLKDIVWECWSHQPQDRPPFSDLQERLAR
|. |||     |||.||...|||.|.. |.  ..     . . .||..| |  .|       ..||...  . .||. |...|| |  . .|.  
DENPYSFQ--SDVYSFGIVMYELMTRHMPYGCHI----WNRDQIIFMCGRGYLRPDLSKVRQDCPKAMHRLMEDCWKFQREERPLFQQILKRITV
Kinase AqueK676.AA TKL 945-1216 22 1.4e-59 204.3 In-house 1-364 (364) Show / Hide 
Range on Protein: 945-1216
Range on HMM: 1-364/364
Sequence Identity: 22% (84 aa)

LGSGPVAEVYKGYWHG-----------EVAVKRFVLPNA------------------------TPKQINKFREEVA-VLKKIRHENLALFMGVCLTTPN-
.|||  .|||||.|.|           .||||.|   |                         .......|.||.. .....||.|. .|||.|.  |. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------LAIITSYCKGYTLYKLLHYWSEAFSLERLANIGRQIAQAMGYLHA--------RGIIHKGLNTKNIFLEKRDQ-----------KEKV
            |.|.. ||.| .|. .||       .... .. ..||..| |||.        ..|||  |..|||.. .  .             ..
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

IITDMGLSSLSSLLYDNTTSKGGVV-----------TFPRA-QLYSLAPEIIRKISPTPV----VQIDQEPYSYNYATDVYAFGTILYELITKRFPFSTD
 |.|.|||   |   ... .. ..            | ..   .. .|||..|.  ...      .  .. ..|. ..|||.|| .|.|..| . |.. .
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDE-FCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDY

SLGFAYEF----EVVIFLVGHGHRQPFK------------GETPKKLKDIVWECWSHQPQDRPPFSDLQERL
     . .    |  .  . .|.| | .              .|. .|..  .||.| |..|| |... .||
PYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK676.AA TKL-Unique 941-1216 27 3.1e-48 166.58 In-house 1-290 (290) Show / Hide 
Range on Protein: 941-1216
Range on HMM: 1-290/290
Sequence Identity: 27% (85 aa)

LLEKLGSGPVAEVYKGYWHGE-VAVKRFVLPNATPKQI--NKFREEVAVLKKIR-HENLALFMGVCL----TTPNLAIITSYCKGYTLYKLLH-------
 ..|.|.| ...|||| |.|. ||.|.| . |. .  .   .|..|| ..||.. |.|. ..||.|     . ||. |...|| | .||..||       
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHP-NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

--YWSEAFSLERLANIGRQIAQAMGYLHARG--IIHKGLNTKNIFLEKR--DQKEKVIITDMGLSSLSSLLYDNTTS--KGGVVTFPRAQLYSLAPEIIR
    .  .....  .. ..|||.| ||| ..  |||  | ..|. .  .    . .. | | ||| ..|   ..|..  ||.  . . . .  .|||..|
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLR

KISPTPVVQIDQEPYSYNYATDVYAFGTILYELITKRF------PFSTDSLGFAYEFEVVIFLVGH---GHRQPFKGETPKKLKDIVWECWSHQPQDRPP
              . |.   |||.||..|.|..|         |..      ....| .. .|     . | |   . || ..|.  .|| |.|..|| 
MNF-----------CQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQ------GMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPS

FSDLQERL
|..  .||
FDEIIHRL
Kinase AqueK676.AA Pkinase_Tyr 939-1084 27 7.5e-31 105.11 Pfam 1-158 (270) Show / Hide 
Range on Protein: 939-1084
Range on HMM: 1-158/270
Sequence Identity: 27% (44 aa)

LKLLEKLGSGPVAEVYKGYWH-------GEVAVKRFVLPNATPKQ--INKFREEVAVLKKI-RHENLALFMGVCL-TTPN--LAIITSYCKGYTLYKLLH
.....|||.|   |||||.|.        .||||    ..|...|  . .| .|....|.. .|.|.  ..|||.       . |.. |...  |.. |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

YW---SEAFSLERLANIGRQIAQAMGYLHARGIIHKGLNTKNIFLEKRDQKEKVIITDMGLS
      .......| .. .|||..| ||.....||  | ..|. ...   . .| |.| ||.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE---NNVVKICDFGLA
Kinase AqueK676.AA Pkinase 939-1158 23 1.8e-30 108.84 Pfam 1-213 (293) Show / Hide 
Range on Protein: 939-1158
Range on HMM: 1-213/293
Sequence Identity: 23% (55 aa)

LKLLEKLGSGPVAEVYKGYWHGE---VAVKRFVLPNATPKQINKFRE--EVAVLKKIRHENLALFMGVCLTTPNLAIITSYCKGY----TLYKLLH-YWS
.....|.|||  ..|||....|.   ||||.. .... ...    |   |....|...|.|   . ... . ... ... || |      |. ...   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

EAF--SLERLANIGRQIAQAMGYLHARGIIHKGLNTKNIFLEKRDQK-EKVIITDMGLSSLSSLLYDNTTSKGGVVTFPRAQLYSLAPEIIRKISPTPVV
 .|  | . . .. .||.... |.|..||||  |   ||.. ....  ..| |.| ||. . .      . ...  | .   .. .|||.||        
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD------Y-NNS-MTTFCGTPWYMAPEVIR--------

QIDQEPYSYNYATDVYAFGTILYELITKRFPFS
    .   | .. |....| ||||....|.||.
----GGQYYGPKVDMWSCGCILYEMLCGRPPFP
Kinase AqueK676.AA S_TKc 939-1217 20 3e-29 104.39 SMART 1-231 (231) Show / Hide 
Range on Protein: 939-1217
Range on HMM: 1-231/231
Sequence Identity: 20% (61 aa)

LKLLEKLGSGPVAEVYKGYWHG---EVAVKRFVLPNATPKQINKFREEVAVLKKIRHENLALFMGVCLTTPNLAIITSYCKG--YTLYKLLHYWSEA---
 ..|.|.|.|  ..|||.....   .||.|.           ...| |...||| .|.|.  . .|. .  .| ... || |   .|.....        
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--FSLERLANIGRQIAQAMGYLHARGIIHKGLNTKNIFLEKRDQKEKVIITDMGLSSLSSLLYDNTTSKGGVVTFPRAQLYSLAPEIIRKISPTPVVQID
  |.  . . . .||..|. |.| .||||  |   ||.| .      . |.| ||. .          .  ..|     .. .|||..            
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL---------TTFCGT-----PWYMAPEVL------------

QEPYSYNY-ATDVYAFGTILYELITKRFPFSTDSLGFAYEFEVVIFLVGHGHRQPFKGETPKKLKDIVWECWSHQPQDRPPFSDLQE--------RLA
    .|.. . |....| ||||... . ||.        . .... ..|           .. .||..  |.   |..||   .. .           
----GYGKCKCDWWSCGCILYEMLCGYPPFP--------QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK676.AA Dicty4 939-1057 34 2.5e-25 81.56 In-house 1-137 (277) Show / Hide 
Range on Protein: 939-1057
Range on HMM: 1-137/277
Sequence Identity: 34% (48 aa)

LKLLEKLGSGPVAEVYKGYWHG-EVAVKRFVLPNAT--PKQINKFREEVAVLKKIRHENLALFMGVCL----TTPNLAIITSYC-KGYTLYKLLHY----
..  ...|.|  .||||| | | ||||| . . | .   . .| || ||. ..|||| |. |||| |.    . . . | | |. || .||.|||     
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKG-NLYSLLHDKPSE

--WSEAFSLERLAN---IGRQIAQAMGYLHARG--IIH
   |   ....      ... .|. | .||..   |||
QQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIH
Kinase AqueK676.AA MLK 939-1065 30 7.5e-24 79.7 In-house 1-158 (291) Show / Hide 
Range on Protein: 939-1065
Range on HMM: 1-158/291
Sequence Identity: 30% (48 aa)

LKLLEKLGSGPVAEVYKGYWHG-E-----VAVKRFV----LPNATPKQINKFREEVAVLKKIRHEN----LALFMGVCLTTPN-LAIITSYCKGYTLYKL
....|..|||.  .|.||.|.. .     |||||.         |  .. .|..|.  |....|.|       |.|||| .|. ..|.. || |  || .
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LHY----WSEA---------FSLERLANIGRQIAQAMGYLHARG---IIHKGLNTKNI
||     |. |          ... ..|.  |.|..| |||.     |||  |. .||
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNI
Kinase AqueK676.AA TK 939-1092 14 1.3e-23 75.36 In-house 82-392 (486) Show / Hide 
Range on Protein: 939-1092
Range on HMM: 82-392/486
Sequence Identity: 14% (46 aa)

LKLLEKLGSGPVA---EVYKGYWHG----------------------------EVAVKRFVLP-NATPK-QIN-------------KFREEVAVLK--KI
..|..|||.|      ||||| |.|                            .||||   .  ..... ..              .. || ....  . 
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHENLALFMGVCLTT------------PNLAIITSYCKGYT----LYKLLH-------------------------------------------------
.|.|.  . |||.              . . |.. |...      | . |.                                                 
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

----------------------YWSEA-----FSLERLANIGRQIAQAMGYLHAR------GIIHKGLNTKNIFLEKRDQKEK--------VIITDMGLS
                      .|. .     .....|  . .|||..| |||..      ...|  | . |. . ..... .        . |.| |||
DDDLIKDHPPPLTTKDLLQMAWQWC-LTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

S-----LSSLLYD
      |.  .|.
RQGSGVLARDIYS
Kinase AqueK676.AA Src 939-1065 34 3.8e-20 65.12 In-house 1-128 (255) Show / Hide 
Range on Protein: 939-1065
Range on HMM: 1-128/255
Sequence Identity: 34% (45 aa)

LKLLEKLGSGPVAEVYKGYWHG--EVAVKRFVLPNATPKQINKFREEVAVLKKIRHENLALFMGVCLTT-PNLAIITSYCKGYTLYKLLH--YWSEAFSL
.||..|||.|   ||..||| |  .||||  .|  .|  . . | .|  ..|| |||.|     || .  | . |.| | .   | . |.      . .|
IKLCRKLGQGQFGEVWMGYWNGNTKVAVK--TLKPGT-MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIY-IVTEYMSHGSLLDYLKKDGEGRHLHL

ERLANIGRQIAQAMGYLHARGIIHKGLNTKNI
..|  .. |.|. | || .. .||  |  .|.
PQLIDMAAQVAEGMAYLESMNYIHRDLAARNV
Kinase AqueK676.AA Dicty4-Unclassified 939-1084 27 9.9e-19 60.75 In-house 1-156 (263) Show / Hide 
Range on Protein: 939-1084
Range on HMM: 1-156/263
Sequence Identity: 27% (43 aa)

LKLLEKLGSGPVAEVYKGYWHG-EVAVKRFVLPNATPK--QINKFREEVAVLKKIRHENLALFMGVCLTT----PNLAIITSYCKGYTLYKLLH----YW
.. .  .| |  ..|.|| | | .|||| |           |  |. ||..|  | | ||    | |.        . |..      .|  . |      
IQIDQFIGKGHFSKVHKGNWKGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQ

SEAFSLER--LANIGRQIAQAMGYLHARGIIHKGLNTKNIFLEKRDQKEKVIITDMGLS
    .|.      .   ||| | .|| | .||  .   || .   |    . | |.|.|
QQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILM---DKHFNIKIADFGIS
Kinase AqueK676.AA TyrKc 939-1216 25 1.3e-17 62.28 SMART 1-280 (280) Show / Hide 
Range on Protein: 939-1216
Range on HMM: 1-280/280
Sequence Identity: 25% (78 aa)

LKLLEKLGSGPVAEVYKGYWHGEVAVKRFVLPNATPKQINKFREEVAVLKKI--RHENLALFMGVCLTT-------PNLAIITSYCKGYTLYKLLHYWSE
..|..|||.|   ||||| |  .||||           .  |..|  ...|.  .|.|.  . |||..        . | |.. |...  | . |..  .
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

AFSLERLANIGRQIAQAMGYLHARGIIHKGLNTKNIFLEKRDQKEKVIITDMGLSSLSSLL--------YDNTTSKGGVVT-FPRAQLYSLAPEIIRKIS
 .... | ..  |||. | ||| ...||  | . |. . ..     | |.| |||              |  .....|  | .|   .  .||| |    
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLP---IRWMAPECI----

PTPVVQIDQEPYSYNYATDVYAFGTILYELITK-RFPFSTDSLGFAYEFEVVIFLVGHGHRQPFKGE--------TPKKLKDIVWECWSHQPQDRPPFSD
           . .. ..||..||  ..|. |    | . . .    . . || .| .|.| |   .         |... .|  .|| ..| ||| ||.
---------NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSE

LQERL
. |..
IHECF
Kinase AqueK676.AA TK 1134-1216 21 2.9e-13 40.07 In-house 371-486 (486) Show / Hide 
Range on Protein: 1134-1216
Range on HMM: 371-486/486
Sequence Identity: 21% (25 aa)

YNYATDVYAFGTILYELIT---KRFPFSTDSLGFAYE---FEVVIFLV-------------GHGHRQPFKGETP--------------KKLKDIVWECWS
.  ..||..||  ..|. |   . ..   .. . .      ||. .|.             |...|.|     |              . . |.  .||.
FTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWH

HQPQDRPPFSDLQERL
..|.||| ||.|.|.|
YDPEDRPTFSQLHEQL
Kinase AqueK676.AA MLK 1134-1216 24 3.3e-11 35.24 In-house 213-291 (291) Show / Hide 
Range on Protein: 1134-1216
Range on HMM: 213-291/291
Sequence Identity: 24% (20 aa)

YNYATDVYAFGTILYELITKRFPFSTDSLGFAYEFEVVIFLVGHGHRQPFKGETPKKLKDIVWECWSHQPQDRPPFSDLQERL
|. . ||. .| .|.|..|.. |..    .  ..... .  . .| | |   . |. .|    .||.  | .|| |.  .. |
YSEKCDVWSWGVVLWEMLTREVPYK----QHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase AqueK676.AA Dicty4 1133-1218 28 3.6e-10 30.28 In-house 193-277 (277) Show / Hide 
Range on Protein: 1133-1218
Range on HMM: 193-277/277
Sequence Identity: 28% (26 aa)

SYNYATDVYAFGTILYELITKRFPFS--TDSLGFAYEFEVVIFLVGHGHRQPFKGETPKKLKDIVWECWSHQPQDRPPFSDLQER--LAR
.|| . ||| || .|.|. |.  |..   ...     ...|.  . .. | |    .|...|. . .||.| || || |.   .|  |  
PYNEKADVYSFGIVLWEILTRQEPYQKHHMPY-----MQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase AqueK676.AA Dicty4-Unclassified 1133-1216 23 2.6e-08 24.54 In-house 184-263 (263) Show / Hide 
Range on Protein: 1133-1216
Range on HMM: 184-263/263
Sequence Identity: 23% (20 aa)

SYNYATDVYAFGTILYELITKRFPFSTDSLGFAYEFEVVIFLVGHGHRQPFKGETPKKLKDIVWECWSHQPQDRPPFSDLQERL
||| . ||| .. .||||.|   |.    ..     .. .     . |       .  .|  .  ||.  |. || . .  ..|
SYNQKSDVYSYAMMLYELATGDEPY----QEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase AqueK676.AA Src 1138-1216 33 4.9e-08 23.34 In-house 181-255 (255) Show / Hide 
Range on Protein: 1138-1216
Range on HMM: 181-255/255
Sequence Identity: 33% (27 aa)

TDVYAFGTILYELITK-RFPFSTDSLGFAYEFEVVIFLVGHGHRQPFKGETPKKLKD-IVWECWSHQPQDRPPFSDLQERL
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SDVWSFGILLTEIVTYGRVPYP----GMTN--HEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK676.AA Pkinase_Tyr 1197-1216 50 2e-06 22.07 Pfam 251-270 (270) Show / Hide 
Range on Protein: 1197-1216
Range on HMM: 251-270/270
Sequence Identity: 50% (10 aa)

ECWSHQPQDRPPFSDLQERL
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QCWHYDPEDRPTFSEIHEQL
Kinase AqueK676.AA Pkinase_Tyr 1134-1152 31 0.344791 4.65 Pfam 191-209 (270) Show / Hide 
Range on Protein: 1134-1152
Range on HMM: 191-209/270
Sequence Identity: 31% (6 aa)

YNYATDVYAFGTILYELIT
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FTTKSDVWSFGVLMWEIFT