Gene AqueK684 (A.queenslandica)

AqueK684

Species: A.queenslandica
Alias: AqueK684
External Links:
Annotation:

Classification

Group: TKL
Family: STKR
Subfamily: STKR2

Sequence

Name Sequence Type Origin Length Description Download
AqueK684.AA Protein None 959 None Fasta, JSON
AqueK684.kin_dom Protein Kinase Domain None 209 None Fasta, JSON

Protein domain

Protein domains of AqueK684.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
EGF_CA AqueK684.AA EGF_CA 139-153 22 18.403767 0.88 Pfam 32-53 (53) Show / Hide 
Range on Protein: 139-153
Range on HMM: 32-53/53
Sequence Identity: 22% (5 aa)

V---CPETFS----SNPDDHSC
|   |.. ..     |.|.. |
VNQDCMDGYEMISENNCDGTNC
EGF_CA AqueK684.AA EGF_CA 234-274 39 2.5e-10 41.56 SMART 1-34 (34) Show / Hide 
Range on Protein: 234-274
Range on HMM: 1-34/34
Sequence Identity: 39% (18 aa)

DIDECAINNGGCSE-----TCINTPGNYSCECNAGRYLSPHSGRCE
|||||      |.      |||| || |.| | .| .     ..||
DIDEC-----PCQNGGPTGTCIN-PGSYRC-CPPGYT-----RHCE
EGF AqueK684.AA EGF 237-274 30 4e-06 27.44 SMART 1-32 (32) Show / Hide 
Range on Protein: 237-274
Range on HMM: 1-32/32
Sequence Identity: 30% (14 aa)

ECAINNGGCSE-------TCINTPGNYSCECN-AGRYLSPHSGRCE
|||    .|..       |||     |.| |  .| ..     |||
ECA----PCHHGGCEQHGTCI----SYTC-CPGPGYTG-----RCE
EGF_CA AqueK684.AA EGF_CA 234-273 28 9e-06 20.71 Pfam 1-53 (53) Show / Hide 
Range on Protein: 234-273
Range on HMM: 1-53/53
Sequence Identity: 28% (15 aa)

DIDECAINN-GGC-----SETCINTPGNYSCE---CNAG-R---YLSPHSGRC
|.||||.     |     ...|||| | ..|.   | .| .   .  . .. |
DVDECADGTHHMCGDPHRNTWCINTIGSFECVNQDCMDGYEMISENNCDGTNC
EGF AqueK684.AA EGF 238-263 46 1.8e-05 21.37 Pfam 1-28 (36) Show / Hide 
Range on Protein: 238-263
Range on HMM: 1-28/36
Sequence Identity: 46% (13 aa)

CAINNGGCSE--TCINTPGNYSCECNAG
|. ||..|.   ||..||| |.|.|  |
CNPNNNPCHHHGTCVDTPGGYTCQCPPG
Kinase AqueK684.AA STKR 479-768 37 6.5e-123 398.74 In-house 2-312 (312) Show / Hide 
Range on Protein: 479-768
Range on HMM: 2-312/312
Sequence Identity: 37% (116 aa)

EFMKIIGHGRFARVYHARMGT----RDVAIKIFNGTLQAKGSWTQEKDIYATERLEHENILKFLYHDHRFH-EGQDTLWLIFDYHSNGSLYDYLQLHRLT
.....|| ||.. |....       ..||.|||.   . . ||  |..|| |  ..||||| |.  | .    .   .||| .|| ||||.|||. | ..
QLIECIGKGRYGEVWKGKWRGNGEKETVAVKIFP--SRDEQSWFRETEIYQTPMMRHENILQFIAADMKHTEGSWTQYWLITEYHENGSLCDYLKRHTID

FDELFSLCLSGAAGLEHLHSVDN--CPET-YKPAIAHRDLKSKNILVKKDMTCCISDFGLAIKFDGVDMILSEA--------KGQVGTSRYMAPEILEGA
..|.  ...| | || |||      .    .||||||||.||||||||.|.|||| |||||...|.    .  .         .|||| ||||||.|.||
WHEMCRMAHSMACGLAHLHMEIWGWGTQQHHKPAIAHRDIKSKNILVKNDGTCCIADFGLAMRHDPDTNQIDIHNTMQDNAQNTQVGTKRYMAPEVLDGA

VRFN--QEAFLKIDIYAFGLILWEMLSCCDLNN----ITSNPSYYPPFDGWVSANPSIDEMKRIVVEEKKRPPIPQKFQ-TNLKYSFIADIIVECWDDDA
. |.  ..||. .|.||.||..||... | ..      .. | | .||. ||  .||...|. .|.....||.||   .  .     ..... |||| |.
MNFQCFESAFKRMDMYAMGLVMWEIARRCTDGGPDLVDQIVPEYQMPFYDWVPNHPSFEDMQKVVCRKRQRPNIPNRWKCNHPAMRSMCKTMEECWDHDP

DGRPAASLISRRL
. |  |  .  ..
EARLTALCVKKTM
Kinase AqueK684.AA Type1 479-768 39 1e-116 317.58 In-house 2-290 (290) Show / Hide 
Range on Protein: 479-768
Range on HMM: 2-290/290
Sequence Identity: 39% (116 aa)

EFMKIIGHGRFARVYHARMGTRDVAIKIFNGTLQAKGSWTQEKDIYATERLEHENILKFLYHDHRFHEGQDTLWLIFDYHSNGSLYDYLQLHRLTFDELF
. ...|| ||.  |....    .||.|||. .  .  ||  | .|| |  . |||||.|   | .  .    |||| ||| .|||||||. | |. ... 
QMIECIGKGRYGEVWRGKWRGENVAVKIFFSRDER--SWFRETEIYQTVMMRHENILGFIAADMKDNGSWTQLWLITDYHEHGSLYDYLNRHTLDTQQML

SLCLSGAAGLEHLHSVDNCPE-TYKPAIAHRDLKSKNILVKKDMTCCISDFGLAIKFDGV-DMILSEAKGQVGTSRYMAPEILEGAVRFNQ-EAFLKIDI
 |..| | ||.|||    . .   ||||||||.|||||.|||. .||| |.|||.... . | |      .||| ||||||.|.   ..|. |..   ||
RLAYSCACGLAHLHMEIFGTQEFGKPAIAHRDIKSKNIMVKKNGQCCIADLGLAVRHQQDTDQIDIGQNPRVGTKRYMAPEVLDETMNMNCFESYKMADI

YAFGLILWEMLSCCDLNNITSNPSYYPPFDGWVSANPSIDEMKRIVVEEKKRPPIPQKFQTNLKYSFIADIIVECWDDDADGRPAASLISRRL
|.|||..||..  |  . |     | .|...||   ||...|...|  .| ||.|| ..| .   . .| .  |||   .. |  |  |   |
YSFGLVMWEIARRCEVGGIVED--YQLPYYDWVPNDPSFEDMRKVVCVRKLRPNIPNRWQSHPCMRHMAKLMKECWYQNPHARHTALRIKKTL
Kinase AqueK684.AA Type2 479-768 40 5.2e-113 374.52 In-house 2-315 (315) Show / Hide 
Range on Protein: 479-768
Range on HMM: 2-315/315
Sequence Identity: 40% (127 aa)

EFMKIIGHGRFARVYHARMGTR-----DVAIKIFNGTLQAKGSWTQEKDIYATE-RLEHENILKFLYHDHR---FHEGQDTLWLIFDYHSNGSLYDYLQL
..| .|| |||. |. |.   .     .||.|||.   | | ||. |||||..  ...||||| |.  . |      |.. .||. ..|..|||.|||  
QLMELIGKGRFGCVWKAQWHNNNGEKRTVAVKIFP--EQDKQSWQNEKDIYSLPYHMWHENILQFICAEKRRVHMGDGWMEYWLVTEFHHKGSLCDYLKQ

HRLTFDELFSLCLSGAAGLEHLHSVDNCPET---YKPAIAHRDLKSKNILVKKDMTCCISDFGLAIKFDGVDMI------L-SEAK--GQVGTSRYMAPE
| ... |.  ...| |.|| |||..   .     .||.|||||.||||.||| ||||||.|||||..|..            .. .  ||||| ||||||
HTIDWHECCRMAMSMARGLAHLHEEIWQWCQTDHHKPPIAHRDIKSKNVLVKNDMTCCIADFGLAMRFCPGKQPYKWEPTMPGDTHNIGQVGTRRYMAPE

ILEGAVRFN--QEAFLKIDIYAFGLILWEMLSCCDLNN-ITSNPSYYPPFDGWVSAN-PSIDEMKRIVVEEKKRPPIPQKFQTNLKYS-FIADIIVECWD
 ||||| |.   .||. .|.||.||.||||.| |..     . | | .||   |  . ||...|.  ||...|||..|   . .      . . |..|||
VLEGAVNFQDCRDAFKQMDMYAMGLVLWEMVSRCTDHYPDDEVPEYQMPFEEEVGQHDPSFEDMQELVVRKRKRPQWPDHWKCHPGMQRMLCETIEDCWD

DDADGRPAASLISRRL
 ||. |  |. .  |.
HDAEARLTAQCVQERM
Kinase AqueK684.AA TKL 484-768 25 4e-75 255.9 In-house 1-364 (364) Show / Hide 
Range on Protein: 484-768
Range on HMM: 1-364/364
Sequence Identity: 25% (96 aa)

IGHGRFARVYHARMGT----------RDVAIKIFNGTL-----------------------QAKGSWTQEKDIYATERLE---HENILKFLY--HDHRFH
|| |.|. ||...             .|||.|.|. .                        . . || ... .. .  .    |.||..|.    . .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

E-------GQDTLWLIFDYHSNGSLYDYLQLHRLTFDELFSLCLSGAAGLEHLHSVDN--CPETYKPAIAHRDLKSKNILVKKDMT--------------
.       ..  |... .|...|||..||.     .. .....|. | |...||| .   |    ||.|.|||||||||||....|              
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCT---KPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

CCISDFGLAIKFDGV-DMILSE---------------AKGQVGTSRYMAPEILEGAVRFNQ-----------EAFLKIDIYAFGLILWEMLSCCDLNNIT
|.|.||||.  ...  .|  ..                  |.|| |.||||.|.|.  ...           |.. |.|.|.||..|||.|..|      
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-----

SNPSYYPPFDGWVSANPSIDEMKRIVVEEKKRPPIPQKFQT----NLKYSF---IADIIVECWDDDADGRPAASLISRRL
  | | .|.. .. . | ..||  .|.....|||||   |.        ..   ..... .||| |.. || .. |  ||
--PYYDYPYMPMIFQDP-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Pkinase AqueK684.AA Pkinase 478-768 22 6.8e-50 176.88 Pfam 1-293 (293) Show / Hide 
Range on Protein: 478-768
Range on HMM: 1-293/293
Sequence Identity: 22% (75 aa)

PEFMKIIGHGRFARVYHARMGTRD--VAIKIFNGTLQAKGSWTQEK---DIYATERLEHENILKFLYHDHRFHEGQDTLWLIFDYHSNG----SLYDYLQ
 .. ..|| | |..||...       ||.||..   . .. . .      |.   || |.||.....  ..     | ......|. .|    .|.||..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED----KDHIYMVMEYCEGGLYVMDLFDYIS

---LHRL--TFDELFSLCLSGAAGLEHLHSVDNCPETYKPAIAHRDLKSKNILVKKDMTC----CISDFGLAIKFDGVDMILSEAKGQVGTSRYMAPEIL
     ..  . .|. . ..  . |||..||           | |||||. |||.......    .|.||||| .||      | ... .||..|||||..
TWRHGCFYFSEWECKFYMYQILRGLEYCHSM---------GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAPEVI

EGAVRFNQEAFLKIDIYAFGLILWEMLSCCDLNNITSNPSYYPPFDGWVSANPSIDEMKRIVVEEKKRPPIPQKFQTNLKY-----------------SF
     ..|.   |.|....|.||.|||.              |||.| .   .. .... .... ...|.  . .... ..                 . 
R----GGQYYGPKVDMWSCGCILYEMLCGR------------PPFPGHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEE

IADIIVECWDDDADGRPAASLISRR--L
  |.|  |.. |   || |  |     .
CKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK684.AA TKL-Unique 480-687 27 9.8e-29 98.54 In-house 1-223 (290) Show / Hide 
Range on Protein: 480-687
Range on HMM: 1-223/290
Sequence Identity: 27% (64 aa)

FMKIIGHGRFARVYHARMGTRDVAIKIFNGTLQAKG-SWTQ--EKDIYATERLE-HENILKF--LYHDHRFHEGQDTLWLIFDYHSNGSLYDYLQ-----
| . || | ...||..   . .||||.|.  .  .  . .|  |. .   ..|. |.||...    .||  ....  . .. .| . |||||.|.     
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHP-NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPN--MCIVMEYCPGGSLYDVLHQNNNN

------LHRLTFDELFSLCLSGAAGLEHLHSVDNCPETYKPAIAHRDLKSKNILVKKD-----MTCCISDFGLAIKFD-GVDMILSEA-----KGQVGTS
       . |..    .. .  | |...||.       ..| |.||||||.|.||  .     .   |.||||..  .   .|...|       . .|. 
NNNNNNNCKLNMQQRVKMAIDIAQGMYYLHH-------CEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSF

RYMAPEILEGA-VRFNQEAFLKIDIYAFGLILWEMLS
|.||||.|..    ...    |.|.|.|| .|||...
RWMAPEVLRMNFCQYSE----KSDVYSFGIVLWEIAT
S_TKc AqueK684.AA S_TKc 478-772 23 4.5e-27 97.18 SMART 1-231 (231) Show / Hide 
Range on Protein: 478-772
Range on HMM: 1-231/231
Sequence Identity: 23% (73 aa)

PEFMKIIGHGRFARVYHARMGT--RDVAIKIFNGTLQAKGSWTQEKDIYATERLEHENILKFLYHDHRFHEGQDTLWLIFDYHSN--GSLYDYLQLHR--
 |....||.| |..|| .|     | ||||| .       .  .| .|       |.|| |.... .      | |.....| ..  |.|.||.. ..  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK---HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----LTFDELFSLCLSGAAGLEHLHSVDNCPETYKPAIAHRDLKSKNILVKKDMTCCISDFGLAIKFDGVDMILSEAKGQVGTSRYMAPEILEGAVRFN
     ..  .  ...   . .||..||           | |||||  |||. .  .  |.||||| ..          . ..||  |||||.|       
GLRFPFPE-HARFYMYQICCALEYCHSHG---------IIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL-------

QEAFL--KIDIYAFGLILWEMLSCCDLNNITSNPSYYPPFDGWVSANPSIDEMKRIVVEEKKRPPIPQKFQTNLKYSFIADIIVECWDDDADGRPAASLI
   .   |.|....| ||.|||.             ||||.        ...| ....                  ...  .|  |.. | . || |  .
--GYGKCKCDWWSCGCILYEMLCG------------YPPFP-------QMQMMFKKIG----------------SPEAKD-FIRKCLQKDPEKRPTA-EA

SR-----RLSEFQ
 .     .. .. 
LQDEWDIKCHPWF
Kinase AqueK684.AA MLK 478-688 24 8e-24 79.6 In-house 1-232 (291) Show / Hide 
Range on Protein: 478-688
Range on HMM: 1-232/291
Sequence Identity: 24% (62 aa)

PEFMKIIGHGRFARVYHARMGTRD-----VAIKIFNGTLQAKGS-----WTQEKDIYATERLEHEN----ILKFLYHDHRFHEGQDTLWLIFDYHSNGSL
 .| ..||.| |  |. .|.  .|     ||.|... .  .|..     |  |....   .| |.|    | .|..     .. .  . ..  | ..|||
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGV---CLQPPCHFCIVMEYCEGGSL

YDYLQLHR---------------LTFDELFSLCLSGAAGLEHLHSVDNCPETYKPAIAHRDLKSKNILVK------KDMTCCISDFGLAIKFDGV-D-MI
|..|   |                ..| ... .|  | |.. ||| .      ...| ||||||.|||.       ...|. |.|||.. ..    . | 
YNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMA------PKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMM

LSEAKGQVGTSRYMAPEILE--GAVRFNQEAFLKIDIYAFGLILWEMLSC
     .. || ..||||...   . ...  .    |.. .|..|||||..
-----SNAGTYAWMAPEVIQQFRCEKYSEKC----DVWSWGVVLWEMLTR
Kinase AqueK684.AA TK 478-768 14 2.2e-22 71.15 In-house 1-486 (486) Show / Hide 
Range on Protein: 478-768
Range on HMM: 1-486/486
Sequence Identity: 14% (73 aa)

PEFMKIIGHGRFA---RVYHA---------------------------RMGTRDVAIKIFNGTLQAKGSWTQ------------------EKDIYATERL
 .. | .|.| |    .|| .                           ..|. .||.|.   .  .     .                  |  .   . .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

EHENILKFLY--HDHR-------FHEGQDTLWLIFDYHSNGS----LYDYLQLHR---------------------------------------------
.|.||....   ....       .  .|  ....  | ..|.    | |||. .|                                             
HHPNIVRLYGVCTQGEPKPCFEVV-VHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQD

------------LTFDELFS-------------------LCLSGAAGLEHLHSV--DNCPETYKPAI---AHRDLKSKNILVKKDMT-----------CC
            ||. .| .                    |.  |.|.|.|||             |    ||||   |.|| ....           | 
YDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCE-F-------IQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCK

ISDFG--------LAIKFD--GVDMILSEAKGQVGTSR----------------------YMAPEILEGAV--------RFNQEAFLKIDIYAFGLILWE
|.|||        || . .  .     |. .. ..  .                      .|||| |.. |        .|  .     |...||  .||
IADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPM-WPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKS----DVWSFGVLMWE

MLSCCD------LNN---ITSNPSYYPPFDGWVSANPSIDEMKRIVVEE-----------KKRPPIPQKFQTNLKY-----------SFIADIIVECWDD
... ..      ..|   ...              . . .|. . ....             | . ||  .   .             ...|.. .||. 
IFTYGQEPYYGGMSNQDVWKD--------------G-DNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHY

DADGRPAASLISRRL
|.. ||  | . ..|
DPEDRPTFSQLHEQL
Kinase AqueK684.AA Ciliate-E2 478-687 23 5.5e-21 68.75 In-house 1-291 (365) Show / Hide 
Range on Protein: 478-687
Range on HMM: 1-291/365
Sequence Identity: 23% (74 aa)

PEFMKIIGHGRFARVYHA-RMGT-RDVAIKIFNGTL----------------------QAKGSWTQEKDIY--------------ATERLEHENILKFLY
 .| |.|| | |. || . .  . ...||||.. ..                      . . .. ||..|.                |.| | ||.|. .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

HDHRFHE-GQDTLWLIFDYHSNGSLYDYLQLH------------RLTFDELFSLCLSGAA---------------GLEHLHSVDNCPETYKPAIAHRDLK
.   | |  .... |...| . |.|.||.. .            ..|  |   .    .                .||.|||        |  | |||.|
C---FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHS--------KNNIIHRDIK

SKNILVKKDMTCCISDFGLAIKFDGV---------DMILSEAKG--------------------QVGTSRYMAPEILEGAVRFNQEAF----LKIDIYAF
  |||.     ..|.||||. |.|             .. . |.                    ..||  |||||||.|    ||...     |.||...
PENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSL

GLILWEMLS
| || |||.
GVILYEMLF
Kinase AqueK684.AA LRRK 585-687 36 2.3e-20 68.71 In-house 174-277 (351) Show / Hide 
Range on Protein: 585-687
Range on HMM: 174-277/351
Sequence Identity: 36% (43 aa)

AAGLEHLHSVDNCPETYKPAIAHRDLKSKNILV---K---------KDMTCCISDFGLAIKFDGVDMILSE-AKGQVGTSRYMAPEILE--GAVRFNQEA
| |.|.||| .       | | |||||| |||.   .          .... |.|||.   |     .... ||| ||. ..|||||.   | . ...  
AKGMEYLHSHN-------PPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMF---QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTE--

FLKIDIYAFGLILWEMLS
  |.|.|.||.|||| |.
--KVDCYSFGMILWELLT
Kinase AqueK684.AA Dicty4 580-686 33 2.1e-17 54.74 In-house 117-211 (277) Show / Hide 
Range on Protein: 580-686
Range on HMM: 117-211/277
Sequence Identity: 33% (36 aa)

LCLSGAAGLEHLHSVDNCPETYKPAIAHRDLKSKNILVKKDMTCCISDFGLAIKFDGVDMILSEAKGQVGTSRYMAPEILEGAVRFNQEAFLKIDIYAFG
.... | |. .||. .       | | |||||| |.|| |...  ..||||.  .  . .    .....||  .||||.. .  ..|. |    | | ||
MAFDAARGMNWLHCCN-------PVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQ-PYNEKA----DVYSFG

LILWEML
..|||.|
IVLWEIL
Kinase AqueK684.AA TyrKc 478-768 23 1.2e-16 46.45 SMART 1-280 (280) Show / Hide 
Range on Protein: 478-768
Range on HMM: 1-280/280
Sequence Identity: 23% (76 aa)

PEFMKIIGHGRFARVYHARMGTRDVAIKIFNGTLQAKGSWTQEKDIYATERL--EHENILKFLYHDHRFHEGQ-------DTLWLIFDYHSNGSLYDYLQ
 .. |..|.| | .||....  ..||.|  .     .    .|  .    .|  .|.||....         |       . |.... | ..|.| |||.
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA--REDFMRE--ARIMCKLGGHHPNIVRLYG----VCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

LHR--LTFDELFSLCLSGAAGLEHLHSVDNCPETYKPAIAHRDLKSKNILVKKDMTCCISDFGLAIKFDGV-------DMILSEA--KGQ-VGTSRYMAP
 ||  |. ..| | |.  |.| |.|||           . ||||   |.||... |. ||||||. . .         |.. .     |  .   | |||
KHRPKLCMKDLLSFCWQIACGMEYLHSK---------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAP

EILEGAVRFNQEAFL----KIDIYAFGLILWEMLSCCDLNNITSNPSYYPPFDGWVSANPSIDEMKRIVVEEKKRPPIPQKFQTNL----KYSFIADIIV
| .          .     | |...||  .||... ..           .|  | .    | .|. . | . . .|. |      .      . . .|. 
ECI---------NYGKFTTKSDVWSFGVCMWEIFTYGQ-----------QPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MSFVCCPDEMYQIMK

ECWDDDADGRPAASLISRRL
.||. |.. ||  | | ...
QCWHEDPEDRPTFSEIHECF
Kinase AqueK684.AA Pkinase_Tyr 479-631 26 4e-15 51.85 Pfam 2-158 (270) Show / Hide 
Range on Protein: 479-631
Range on HMM: 2-158/270
Sequence Identity: 26% (45 aa)

EFMKIIGHGRFARVYHARMG------TRDVAIKIF--NGTLQA--KGSWTQEKDIYATERL-EHENILKFLYHDHRFHE-GQDT--LWLIFDYHSNGSLY
.|.| .|.| | .||....       . .||.|.   . . ..  . .  .|  |  .  |  |.||....          ..   ..... |  .|.|.
TFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQ--LGHHPNIVRLYG----VCTDQGEPNQIYIVMEYMPHGDLL

DYLQLH-----RLTFDELFSLCLSGAAGLEHLHSVDNCPETYKPAIAHRDLKSKNILVKKDMTCCISDFGLA
|||. |     .||  .| . |.  |.|.|.|.|           . ||||  .|.||...... |.|||||
DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---------CIHRDLAARNCLVTENNVVKICDFGLA
Kinase AqueK684.AA LRRK 722-770 36 4.4e-05 13.91 In-house 302-351 (351) Show / Hide 
Range on Protein: 722-770
Range on HMM: 302-351/351
Sequence Identity: 36% (18 aa)

VEEKKRPPIPQKFQTN-LKYSFIADIIVECWDDDADGRPAASLISRRLSE
. |. ||.||| ...  .      | |..||. | . || .| |  |||.
IIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase AqueK684.AA Dicty4 721-770 34 0.000103 11.84 In-house 231-277 (277) Show / Hide 
Range on Protein: 721-770
Range on HMM: 231-277/277
Sequence Identity: 34% (18 aa)

VVEEKKRPPIPQKFQTNLKYSFIADIIVECWDDDADGRPAASLISRR--LSE
|...| |||||. . ...|     . |..||| |   ||  . |. |  | .
VCNKKLRPPIPDWCPPSWK-----HLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase AqueK684.AA TKL-Unique 722-768 36 0.000131 12.38 In-house 249-290 (290) Show / Hide 
Range on Protein: 722-768
Range on HMM: 249-290/290
Sequence Identity: 36% (17 aa)

VEEKKRPPIPQKFQTNLKYSFIADIIVECWDDDADGRPAASLISRRL
.||..|||||.    ...     |.| .||..| . ||  . |  ||
MEENYRPPIPNHCPKEYR-----DLIQQCWHHDPSQRPSFDEIIHRL
Kinase AqueK684.AA MLK 721-768 27 0.001567 8.27 In-house 249-291 (291) Show / Hide 
Range on Protein: 721-768
Range on HMM: 249-291/291
Sequence Identity: 27% (13 aa)

VVEEKKRPPIPQKFQTNLKYSFIADIIVECWDDDADGRPAASLISRRL
|.....|||||. .        ..  . .||..|.  ||  . |   |
VAYNGLRPPIPSTCPEH-----WKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase AqueK684.AA Dicty4 479-508 33 0.006677 5.71 In-house 2-31 (277) Show / Hide 
Range on Protein: 479-508
Range on HMM: 2-31/277
Sequence Identity: 33% (10 aa)

EFMKIIGHGRFARVYHARMGTRDVAIKIFN
 . ..|| | |. || ..    .||.|..|
NIEQRIGKGSFGEVYKGTWRGKEVAVKKLN
Kinase AqueK684.AA LRRK 478-508 20 0.012879 5.06 In-house 1-60 (351) Show / Hide 
Range on Protein: 478-508
Range on HMM: 1-60/351
Sequence Identity: 20% (12 aa)

PEFMKIIGHGRFA-RVYHARMGT----------------------------RDVAIKIFN
 .. . || | |. .|| |..                               .||||..|
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWN
Kinase AqueK684.AA Pkinase_Tyr 743-768 38 0.05575 7.33 Pfam 245-270 (270) Show / Hide 
Range on Protein: 743-768
Range on HMM: 245-270/270
Sequence Identity: 38% (10 aa)

IADIIVECWDDDADGRPAASLISRRL
| |.. .||. |.. ||  | | ..|
IYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK684.AA Pkinase_Tyr 674-690 29 7.917708 0.04 Pfam 196-212 (270) Show / Hide 
Range on Protein: 674-690
Range on HMM: 196-212/270
Sequence Identity: 29% (5 aa)

DIYAFGLILWEMLSCCD
|...||  .||... ..
DVWSFGVLMWEIFTYGE