Gene AqueK705 (A.queenslandica)

AqueK705

Species: A.queenslandica
Alias: AqueK705
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Unique

Sequence

Name Sequence Type Origin Length Description Download
AqueK705.AA Protein None 335 None Fasta, JSON
AqueK705.kin_dom Protein Kinase Domain None 265 None Fasta, JSON

Protein domain

Protein domains of AqueK705.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK705.AA NKF1 18-277 40 1.4e-106 360.43 In-house 1-269 (269) Show / Hide 
Range on Protein: 18-277
Range on HMM: 1-269/269
Sequence Identity: 40% (108 aa)

FTFIRQAGKGTYGTTWIALDKETNSKVAIKAINKTTTNRTSFKKELKYSKHLSKHPHIIKTHDTAFETKT--CYVMVQDYATGGDLFDAIEP--EVGLDA
.. ||| |.|.||    . .. .. ..|.|...|  | .. | .|  |. .|| |.||..| | .|.|    .||..| ||  |||...|.|  ..||. 
YEIIRQLGEGCYGKILLCEHRQSGTRMALKFVPKPQTKLKDFHREFCYGCCLSHHHHIVTTYDVMFQTMDDTYYVFAQEYAPCGDLMEMIQPTNQRGLPE

SKARVYFGQIADALEFMHSKKLVHRDLKPENVVLGDS-EGSYIKLIDFGMTLRTGTHVSRVCGSIPYTPPEICNAKD-EVGFFVEPSCDVWSAGVLLFCM
  .   . | | ||.||||. |||||.||||| . |. . . .|| |||.| ..|. | || ...||..|| | .   . || ..|| |||  |||.|| 
NYCKRCVAQLASALDFMHSRNLVHRDIKPENVLVFDPNDCQRVKLCDFGHTRPRGCTVRRVKHTWPYCAPEVCQELPKNEGFPCDPSHDVWQFGVLIFCC

LTGSFPWEQATLS-DPNFADFVQWQTGK--GRVPHMWRSFSPQLLELFSKLLALDPKDRCKINAVHKYL
||| |||..|    || ...|. ||..|    .|  ||.|.| .. .| |||...|..|... ..|||.
LTGCFPWQKADWMCDPCYEWFMWWQRRKQPPMMPQPWRRFTPRAMRCFRKLLTPHPERRWPVKMMHKYM
Kinase AqueK705.AA S_TKc 18-282 27 2.9e-69 237.34 SMART 1-231 (231) Show / Hide 
Range on Protein: 18-282
Range on HMM: 1-231/231
Sequence Identity: 27% (77 aa)

FTFIRQAGKGTYGTTWIALDKETNSKVAIKAINKTTTNRTSFKKELKYSKHLSKHPHIIKTHDTAFETKTCYVMVQDYATG--GDLFDAIEPEVG-----
....|. |||..|. . . .|.|. .|||| |.       ....|..  |.  .||.|.| .|.  .  ... || .|. |  ||||| |.   .     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK--HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LDASKARVYFGQIADALEFMHSKKLVHRDLKPENVVLGDSEGSYIKLIDFGMTLRTGTHVSRVCGSIPYTPPEICNAKDEVGFFVEP-SCDVWSAGVLL
 ..   || |. ||..|||..||.. .||||||||. | .     ||..|||.  .     . .||.  | .||..           . .||.|| |..|
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL----TTFCGTPWYMAPEVL--------GYGKCKCDWWSCGCIL

FCMLTGSFPWEQATLSDPNFADFVQWQTGKGRVPHMWRSFSPQLLELFSKLLALDPKDRCKINAVHK----YLSEPWY
. ||.|  |..          ... ..  .          ||..... .|.|  ||..|  .  . .      . || 
YEMLCGYPPFP---------QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK705.AA CAMKL 18-282 29 1.6e-68 217.77 In-house 1-297 (297) Show / Hide 
Range on Protein: 18-282
Range on HMM: 1-297/297
Sequence Identity: 29% (91 aa)

FTFIRQAGKGTYGTTWIALD-KETNSKVAIKAINKTTTNRTSFKK----------------ELKYSKHLS--KHPHIIKTHDTAFETKTC------YVMV
...... |||..|.   |.. . |. ||||| |.|  ..   ..|                | .  |.|.  |||.||| ... .||...      ...|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEV-IETPEHDIETKKIYLV

QDYATGGD--LFDAI--EPEVG--LDASKARVYFGQIADALEFMHSKKLVHRDLKPENVVLGDSEGSYIKLIDFGMT-------LRTGTHVSRVCGSIPY
  |. ||.  ||| |  .....  .. . || || || .|....||.. ||||.||||. | ..  . ||.||||.          .|   .  ||| ||
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

TPPEICNA--KDEVGFFVEPSCDVWSAGVLLFCMLTGSFPWEQATLS--DPNFADFVQWQTGKGRVPH-MWRSFSPQLLELFSKLLALDPKDRCKINAVH
 .|||..   |.  |. |    |.||.||.|. |..| .|....|..    .      |.. .|      | . | ..  | .|.|  .|..| .|  . 
MAPEIFQGNNKPYDGPKV----DIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQI-

KYLSEPWY
  .. ||.
--MNHPWM
Kinase AqueK705.AA CAMK 23-282 21 1.9e-64 206.27 In-house 1-425 (425) Show / Hide 
Range on Protein: 23-282
Range on HMM: 1-425/425
Sequence Identity: 21% (94 aa)

QAGKGTYGTTWIALDKETN------------SKVAIKAINKT-----------------------------TTNRTSFKKELKYSKHLSK------HPHI
. |.|..|.   . .|.|.             ||||| |.|.                               .| ....|..  |.|..      ||.|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKTHD-------------------TAFETKTCYVMVQ---DYATGG----DLFDAI--EPE-------------VGLDASKARVYFGQIADALEFMHSKK
|| ..                   .  .......||    .|..||    |||| |   .                .. . || || ||..|....||..
IKLYEVYEDPHYFKNTNDYETSKQVF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

LVHRDLKPENVVLGDSEGS--------------Y-IKLIDFGMT--LRT------------------------GTHVSRVCGSIPYTP-PEICNAK----
 |||||||||. | |....              . ||.||||.   ..                         |   . .||. .| . ||. | |    
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

-----DEVGFFVEPSCDVWSAGVLLFCMLTGSFPWEQATLSDPN---------FADFVQWQTGKGR-VPHMWRS--------------------FSPQLL
     ||    . |.||.||.||.|. ||.| .|..  . ..              | . ..|| .  |...                      .|..  
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

ELFSKLLALDPKDRCKINAVHKYLSEPWY
 | .|.|  ||..| .|  .   |. ||.
DLIRKMLQVDPEKRMTIEQC---LNHPWM
Kinase AqueK705.AA Pkinase 18-268 25 4.5e-57 200.72 Pfam 1-282 (293) Show / Hide 
Range on Protein: 18-268
Range on HMM: 1-282/293
Sequence Identity: 25% (74 aa)

FTFIRQAGKGTYGTTWIALDKETNSKVAIKAINKTTTNRTSFKK-----ELKYSKHLSKHPHIIKTHDTAFETKTCYVMVQDYATGG----DLFDAIE--
....|. |.|..|. ... .| |. .||.| |.| ...    .      |... |.| .||.|....| .||.|. . ||..|. ||    |||| |.  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYD-WFEDKDHIYMVMEYCEGGLYVMDLFDYISTW

PEVGL--DASKARVYFGQIADALEFMHSKKLVHRDLKPENVVLGDSEGSY---IKLIDFGMT----LRTGTHVSRVCGSIPYTPPEICNAKDEVGFFVEP
 . ..  .   .. |. ||. .||..||.. .||||||||. .  ..|     .|..|||      .  ..  . .||...| .||...     |    |
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR----GGQYYGP

SCDVWSAGVLLFCMLTGSFPWEQA----TLSDPNFADFVQWQTGKGRVPHMWRSFS--------------------PQLLELFSKLLALDPKDRC
..|.||.|..|..||.| .|. ..    .  |...  .   ........  |   .                    . .... ...|..|||.|.
KVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMIC---RIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRP
Kinase AqueK705.AA Ciliate-E2 18-282 20 2.7e-51 174.3 In-house 1-365 (365) Show / Hide 
Range on Protein: 18-282
Range on HMM: 1-365/365
Sequence Identity: 20% (80 aa)

FTFIRQAGKGTYGTTWIALDKETNSKVAIKAINKTT----------------------TNRTSFKKELKYSK---------------HLSKHPHIIKTHD
. ||.. |.|..|. . . ..... ..||| |. .                        .  ..|.|..  .                . .||.||| ..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

TAFE--TKTCYVMVQDYATGGDLFDAIE------------PEVGLDASKARVYFGQIAD---------------ALEFMHSKK-LVHRDLKPENVVLGDS
 .|.  ..... .| .|. |||||| |.                ..  ... .. ||..               |||..|||.  .|||.||||...   
-CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---

EGSYIKLIDFGM-----------------TLRTGTH------------------VSRVCGSIPYTPPEICNAKDEV----GFFVEPSCDVWSAGVLLFCM
    ||.||||.                  . .  .                  . ..||. .| .||| | |..     .     .||.||.||.|..|
----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEM

LTGSFPWEQATLSDPNFADFVQWQTGKGRVPHM---------------WRSFSPQLLELFSK----LLALDPKDRCK-INAVHKYLSEPWY
|.| .|.            . | . .| . |                 | . |..   |..|    .|  ||. |   .. .   |  || 
LFGKPPF------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQI---LNHPWF
Kinase AqueK705.AA AGC 18-267 21 6.7e-51 128.73 In-house 1-373 (395) Show / Hide 
Range on Protein: 18-267
Range on HMM: 1-373/395
Sequence Identity: 21% (83 aa)

FTFIRQAGKGTYGTTWIALDK------ETNSKVAIKAINKTT---------TNRTS----------FKKELKYSKHLSK---------HPHIIK-THDTA
| |..  |||..|. . . .|       |.   |.| ..| .           .|           ...| .  .....         || |.|  |  .
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHY-S

FETKTC--YVMVQDYAT---------GG-DLFDAIE---PEVGLDASKARVYFGQ-------IADALEFMHS-KKLVHRD-LKPENVVLGDSEGSYIKLI
|..|.     .| .|.          || .||  .     |  .| . || |. .       |. |||..|| .. .||| |||||..| .    .||| 
FQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDED--GHIKLT

DFGMTLRTGTH-----------------------------------------------------VSRVCG--SIPYTPPEICNAKDEVGFFVEPSCDVWS
|||.  .  .                                                       .  ||  .  | .|||            ..|| ||
DFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL---------YGKACDWWS

--AGVLLFCMLTGSFPWEQATLSDPNF-----ADFVQWQTGKGRVPHMWR---------------SFSPQLLELFSKLLALDPKDR
   |.|.. ||||  |    .  . |       . .  .  .||. ..|.               .|||..  | .|||  ||..|
FGLGCLMYEMLTGYPPFYGDNPQE-NRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKR
Kinase AqueK705.AA MARK 18-277 31 3.3e-50 162.39 In-house 1-262 (262) Show / Hide 
Range on Protein: 18-277
Range on HMM: 1-262/262
Sequence Identity: 31% (87 aa)

FTFIRQAGKGTYGTTWIALDKETNSKVAIKAIN---KTT-TNRTSFKKELKYSKHLSKHPHIIKTHDTAFE--TKTC-YVMVQDYATGGDLFDAIEPE--
. .... |.|.|..   |..| |. ||||| ..   ..   .. ... |... |.| .||.||| ... .|  |...  ... .|| ||.|.| |.    
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKL-DHPNIIKLFHV-IEQDTEQHQIYLIMEYASGGELYDYIKAHPN

VGLDASKARVYFGQIADALEFMHSKKLVHRDLKPENVVLGDSEG-SYIKLIDFGMTLRT--GTHVSRVCGSIPYTPPEICNAKDEVGFFVEPSCDVWSAG
  |  . ||..| ||  |....|||  ||||.||||. . |..|   ||.||||.  .   |.  .. ||. || .||| . |.  |. |    |.|| |
GRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILI-DENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKV----DIWSLG

VLLFCMLTGSFPWEQATLSDPNFADFVQWQTGKGRVPHMWRSFSPQLLELFSKLLALDPKDRCKINAV--HKYL
|.|. |..|.||.. .| .. .    .  ..|| ..|..    |...  | ..|| ..|..| .|  .  |. .
VVLYFMVCGYFPFDGDTQDYKELYKKI--LRGKYDIPCH---VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase AqueK705.AA Ciliate-E2-Unclassified 18-267 20 2.9e-41 140.89 In-house 1-340 (352) Show / Hide 
Range on Protein: 18-267
Range on HMM: 1-340/352
Sequence Identity: 20% (70 aa)

FTFIRQAGKGTYGTTWIALDKETNSKV-----AIKAINKT-----TTNRTSFK-KELKYSK-------------HLSKHPHIIKTHDTAFE-TKTCYVMV
...|.| |.| .|. . . .|... ..     ..|....      . .. ... ||..  |              |. |||... ..   . .| .  .|
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

QDYATGGDLFDAIE--PE---------------VGLDASKAR-----VYFGQIADALEFMHSKK-LVHRDLKPENVVLGDSEG-SYIKLIDFGMTLRTGT
 .|. ||||.. |.  .                  ..  .|.      || || ..||..|.|.  .|||.||||... .. .  |||.||||   . ..
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

H------------------VSRVCGSIPYT----PPEICNA-KDE---VGFFVEPSCDVWSAGVLLFCMLTGSFPWEQATLSDPN-----------FADF
                    . .||.. |     .||.    . .          .||.|| ||.|..||.| .| .. .  . .           .  .
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA-----YKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQL

VQWQ-TGKGRVPHMW-----RSFSPQLL----ELFSKLLALDPKDR
 |..  ..  .|...        ||.      .|..|.|  .|. |
YQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKR
Kinase AqueK705.AA CAMK-Unique 18-217 22 1.9e-40 131.14 In-house 1-292 (363) Show / Hide 
Range on Protein: 18-217
Range on HMM: 1-292/363
Sequence Identity: 22% (67 aa)

FTFIRQAGKGTYGTTWIALDKETNSKVAIKAINK----TTTNRT-----------------SFKKELKYSKHLSKHPHIIKTHDT---AFETKT------
 ...|  |.|..|   ...|.||  | |.| ..|       . .                 ..|.|.   | . .||.|||  |.    |....      
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMV-DHPNIIKLYDWNNPIFCDRKYPLCDL

---------CYVMVQDYATGGDLFDAIEP--------------------EVGLDA--SKARVYFGQIADALEFMHSKKLVHRDLKPENVVLGDS--E---
          ...|..|..||||||.|                      .  . .  . .. .. ... |...|||.. ||||||.||...  |  .   
IIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNH

---------GSYIKLIDFGMTLRTGTHVSR-----VCGSIPYTPPEICNAKD-------EVGF---FVEPSC---DVWSAGVLLFCMLTGSFP
          . |||.|||.     .  ..     .||...|  |||   |        ||.     ....    | || ||... ||.|. |
HRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPP
Kinase AqueK705.AA MSK 21-277 26 2.1e-40 134.3 In-house 1-277 (277) Show / Hide 
Range on Protein: 21-277
Range on HMM: 1-277/277
Sequence Identity: 26% (76 aa)

IRQA---GKGTYGTTWIALDKETNSKVAIKAIN-------KTTTNRTSFKKELKYSKHLSKHPHIIKTHDTAFETKTCYVMVQDYATGGDLFDAIEPEVG
.. .   |.| ...     ...|.   |.| ..       . |.  |  ..|    ... .|| | . |. || ...   .| .|..|| ||  |     
LKVLGTGGYGKFFICRKCVHHDTGKLYAMKILSKATVVQKRKTAEHT--QTERQCLEMCQQHPNIVNLHY-AFQDQCHTYLVMEYCNGGELFTHIRKREH

LDASKARVYFGQIADALEFMHSKKLVHRDLKPENVVLGDS-EGSYIKLIDFGMTLRTGTH----VSRVCGSIPYTPPEICNA--KDEVGFFVEPSCDVWS
 | | .|......  |...||.|. .||||||||. . |  ..  .||||||    . .         |... | .||. .   . ..|.   ..||.||
FDESECRMIMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDNGHVKLIDFGFARLFPQDEEWRMKSPCFTLHYMAPEMLRRGYAQDGGY--DEACDWWS

AGVLLFCMLTGSFPWEQATLSDP---NFADFVQWQTGKGRVPHM---WRSFSPQLLELFSKLLALDPKDRCKIN--AVHKYL
 ||.|. ||||  |  | . .     | .  .     ||...     | ..||.  .| ..||  |||.| . |   .|  .
LGVILYTMLTGQVPFQQNEDDRQHSCNSHHEIMKRICKGEFSFPGMAWQNMSPDAKDLIQWLLTKDPKKRLGMNDLRAHEWK
Kinase AqueK705.AA CHK1 18-162 30 1.7e-28 97.06 In-house 1-158 (276) Show / Hide 
Range on Protein: 18-162
Range on HMM: 1-158/276
Sequence Identity: 30% (48 aa)

FTFIRQAGKGTYGTTWIALD-KETNSKVAIKAINKTTTN----RTS-FKKELKYSKHLS---KHPHIIKTHDTAFETKTCYVMVQDYATGGDLFDAIEPE
.....  |.|..|    .   . .. .|| | |. ..       ..  .|| .  | ||   ||...|.  .   ... .| ... ||.|||||| |||.
YEVVQTLGEGAFGQVKLCENQRNPEEAVAMKEIHIKGQHKMCFMDNDIRKEYCIQKMLSKIGKHENVIRMMGMRMDPEFYY-LFMEYADGGDLFDKIEPD

VGLDASKARVYFGQIADALEFMHSKK-LVHRDLKPENVVLGDSEGS-----YIKLIDFGM
.|.. . |  || |  ..|.. |..   .|||.||||  | |. .|       |. |||.
CGMPSDEAHRYFKQLISGLKYIHCCGGVTHRDIKPENLLL-DKHDSNDMPDNLKIADFGL
Kinase AqueK705.AA TyrKc 18-277 20 5.1e-14 3.95 SMART 1-280 (280) Show / Hide 
Range on Protein: 18-277
Range on HMM: 1-280/280
Sequence Identity: 20% (61 aa)

FTFIRQAGKGTYGTTWIALDKETNSKVAIKAINKTTTNRTSFKKELKYSKHL-SKHPHIIKTHDTAFETK------TCYVMVQDYATGGDLFDAIEPEVG
 |.... | | .|. . .  |    .||.| ... .  |  | .|..  ..|  .||.|.. .  . . .        . .|  |. .||| | .    .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

-LDASKARVYFGQIADALEFMHSKKLVHRDLKPENVVLGDSEGSYIKLIDFGMTLRTGTH--------VSRV----CGS--IPY--TPPEICNAKDEVGF
 |  ..   .  |||.  |. |||...||||   |. .|.     .|  |||..   . .        . |.    .|   .|.  ..||          
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-----NYG

FVEPSCDVWSAGVLLFCMLT-GSFPWEQ-AT--LSDPNFADFVQWQTGKGRVPHMWRS--------FSPQLLELFSKLLALDPKDRCKINAVHKYL
   .  |||| ||... ..| |  |..  .   .|.     .|.    .|. .    .         .. . .. ..  . ||.||.  ...|...
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVK----QGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK705.AA CHK1 174-282 30 1.6e-13 43.97 In-house 176-276 (276) Show / Hide 
Range on Protein: 174-282
Range on HMM: 176-276/276
Sequence Identity: 30% (34 aa)

CGSIPYTPPEICNAKDEVGFFVEPSCDVWSAGVLLFCMLTGSFPWEQAT-LSDPNFADFVQWQTGK-GRVPHMWRSFSPQLLELFSKLLALDPKDRCKIN
||..||  ||.|  |.    .  |  |.||.||.|. ||||  ||.|.. ...    ....|   |  .    |   . . . |  |.|. .|  |  | 
CGTPPYMAPEVCTGKQ----YRGPPVDIWSCGVVLMAMLTGELPWDQPSHMDC---QEYCWWMDNKHWMHWCPWSKIDCRAICLLRKILCENPNKRATIE

AVHKYLSEPWY
.     . |||
QI---EKDPWY
Kinase AqueK705.AA Pkinase_Tyr 122-140 52 0.000124 16.31 Pfam 119-137 (270) Show / Hide 
Range on Protein: 122-140
Range on HMM: 119-137/270
Sequence Identity: 52% (10 aa)

QIADALEFMHSKKLVHRDL
|||...|. .||...||||
QIAKGMEYLESKNCIHRDL
Kinase AqueK705.AA Pkinase_Tyr 18-77 26 0.001529 12.62 Pfam 1-68 (270) Show / Hide 
Range on Protein: 18-77
Range on HMM: 1-68/270
Sequence Identity: 26% (18 aa)

FTFIRQAGKGTYGTTWIALDK----ETNSKVAIKAINKTTTNR----TSFKKELKYSKHLSKHPHIIK
 ||... |.| .|. . .  |    .|. .||.| .. ... .     .| .|.|  |.| .||.|..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVR