Gene NME7a (Human)

NME7a

Species: Human
Alias: NME7a
External Links:
Annotation:

Classification

Group: NDK
Family: NDK

Sequence

Name Sequence Type Origin Length Description Download
NME7a.AA Protein None 376 None Fasta, JSON
NME7a.NA RNA None 1646 None Fasta, JSON
NME7a.kin_dom Protein Kinase Domain None 133 None Fasta, JSON

Protein domain

Protein domains of NME7a.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
NDK NME7a.AA NDK 91-229 41 9.7e-68 232.28 SMART 1-142 (142) Show / Hide 
Range on Protein: 91-229
Range on HMM: 1-142/142
Sequence Identity: 41% (59 aa)

KEKTLALIKPDAI--SKAGEIIEIINKAGFTITKLKMMMLSRKEALDFHV-DHQSRPFFNELIQFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTD
.|.|...|||||.   . ||||... ..||.|...||| |....|  ... .|...||||.|..|.| ||..||.. ...||..|....|| |..|..  
MERTFIMIKPDAVQRGLIGEIISRFERKGFKIVAMKMMQLTKEQAEEHYAVEHKGKPFFNDLVEFMTSGPVVAMVWEGENAIKTWRTMMGPTNPEVPKEA

ASESIRALFGTDGIRNAAHGPDSFASAAREMELFFPSSGGCG
| ..||. ||||  ||. || ||..||.||....||.|  |.
APGTIRGDFGTDIGRNIVHGSDSPESAEREIAYWFPESEICE
NDK NME7a.AA NDK 92-227 37 6.5e-54 190.22 Pfam 1-140 (140) Show / Hide 
Range on Protein: 92-227
Range on HMM: 1-140/140
Sequence Identity: 37% (53 aa)

EKTLALIKPDAI--SKAGEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNELIQFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDAS
|.|...|||||.   . ||||. . ..||.|  .|||.|.| .|  .  .|. .|||..|..|.| ||..|| . ...|| .|  ..|. |   |.  | 
ERTFIMIKPDAVQRGLIGEIISRFERKGFKIVAMKMMHLTREQAEEHYAEHKGKPFFPDLVEFMTSGPVVAMVWEGENAIKKWREMMGATNPAEAK-EAP

ESIRALFGTDG--IR-NAAHGPDSFASAAREMELFFPSSGG
 .||. |...    | |. || || .||.||. ..|| .  
GTIRGDFAVSIYPGRRNVVHGSDSPESAEREIAFWFPPEEI
DM10 NME7a.AA DM10 3-91 21 7.1e-41 143.03 SMART 1-126 (126) Show / Hide 
Range on Protein: 3-91
Range on HMM: 1-126/126
Sequence Identity: 21% (27 aa)

HSERFVFIAEWYDPNA------SLLRRYELLFYPGDGSVEMH--DVKNH-----RTFLKRTKYDN------------------------LHLEDLFIGNK
..... |.|.|.|...      ...||.....|..|...|..  .|.|.     ..||.|... .                        .| .|...|..
DKQVLCFDAYWDDDVCMKYHEYYRIRRFKIHYYLEDDTIEIFEPHVRNSGIDQFGCFLRRQRVPKPCRENQKYFYCCDQEMYPNDDPEYYHWKDFNVGTT

VNVFSRQLVLIDYGDQYTARQLGSRK
.|||.||....|.|||.|.... ...
INVFGRQFHIYDCGDQFTRNYMEQCY
NDK NME7a.AA NDK 237-375 36 1.1e-58 202.15 SMART 1-142 (142) Show / Hide 
Range on Protein: 237-375
Range on HMM: 1-142/142
Sequence Identity: 36% (52 aa)

TNCTCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDMVTEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHL
...|....||.||. || |.|.. . ..||.| ||.|. ... ..||.|.|..     ..|.|. | |||.|||...  || ||.|...|| .||.... 
MERTFIMIKPDAVQRGLIGEIISRFERKGFKIVAMKMMQLTKEQAEEHYAVEHKGKPFFNDLVEFMTSGPVVAMVWEGENAIKTWRTMMGPTNPEVPKEA

RPGTLRAIFGKTKIQNAVHCTDLPEDGLLEVQYFFKIL---D
 |||.|. ||... .|.||. | ||.   |..|.|.     .
APGTIRGDFGTDIGRNIVHGSDSPESAEREIAYWFPESEICE
NDK NME7a.AA NDK 238-373 36 5.5e-40 143.97 Pfam 1-140 (140) Show / Hide 
Range on Protein: 238-373
Range on HMM: 1-140/140
Sequence Identity: 36% (52 aa)

NCTCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDMVTEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHLR
  |  ..||.||  || |.|.  . ..|| | || | ...|  .||.|.. ||    ..|.|. | |||.||| .. .|| |..||..|. .|. |.   
ERTFIMIKPDAVQRGLIGEIISRFERKGFKIVAMKMMHLTREQAEEHYAEHKG-KPFFPDLVEFMTSGPVVAMVWEGENAIKKWREMMGATNPAEAK-EA

PGTLRAIFGKTK--IQ-NAVHCTDLPEDGLLEVQYFFK---I
|||.|. |...      |.||. | ||.   |  ..|.   |
PGTIRGDFAVSIYPGRRNVVHGSDSPESAEREIAFWFPPEEI