Gene FAM20C (Human)

FAM20C

Species: Human
Alias: FAM20C
External Links:
Annotation:

Classification

Group: PKL
Family: FJ

Sequence

Name Sequence Type Origin Length Description Download
FAM20C.AA Protein None 584 None Fasta, JSON
FAM20C.NA RNA None 2768 None Fasta, JSON
FAM20C.kin_dom Protein Kinase Domain None 296 None Fasta, JSON

Protein domain

Protein domains of FAM20C.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
FJ_kinase FAM20C.AA FJ_kinase 265-560 46 3.7e-186 624.74 In-house 1-351 (351) Show / Hide 
Range on Protein: 265-560
Range on HMM: 1-351/351
Sequence Identity: 46% (162 aa)

SGGTQLKLIMTFQNYGQALFKPMKQTREQETPPDFFYFSDYERHNAEIAAFHLDRILDFRR--VPPVAGRMVNMTKEIRDVTRDKKLWRTFFISPA-NNI
..|||||...||..  .|.||||...|.||.....||...|.|||.|||||||||||.||.  .|||.||.||||.|.. |..|..|..||||||| ||.
GCGTQLKRMFTFADGQRACFKPMWYPRDQEHVINHFYYQNYDRHNGEIAAFHLDRILNFRWNLAPPVVGRVVNMTTEWYPVATDQELQKTFFISPAKNNT

CFYGECSYYCSTEHALCGKP-DQIEGSLAAFLPDLSLAKRKTWRNPWRRSYHKR-KKAEWEVD-----------------PDYCEEVKQTPP-------Y
||||.|..||.|||. |... ...|||..|.||......|| ||.||.|.|||| ||||||.|                 ..||.||||.||       |
CFYGKCHWYCDTEHVVCTDWENLMEGSITAWLPQEPFWPRKKWRHPWQRTYHKRHKKAEWETDQIRVRHGLLKRLGAAHQMNYCKEVKQKPPSPSPEEVY

DSSHRILDVMDMTIFDFLMGNMDRHHYETFEKFGN----------------ETFIIHLDNGRGFGKY----SHDELSILVPLQQCCRIRKSTYLRLQLLA
|...|.||..|| .||.|.|||||||||||....|                |....||||..|||..    .|.||..| ||.|||..|.||. ||| ..
DHGRRLLDWIDMIVFDYLIGNMDRHHYETFNFQWNARIMERPTHNLHRQPDEGMLVHLDNEKGFGHPYRVLFHWELYHLAPLYQCCMFRRSTWQRLQEFH

KEE------YKLSLLMAESLRGDQVAPVLYQPHLEALDRRLRVVLKAVRDC
...      ..|. || ||.. |...|||...|..||.||...|.|.|..|
NGPDVGRRLRRLFELMRESMPRDPLHPVLWDKHYKALQRRIDRVYKHVHHC
DUF1193 FAM20C.AA DUF1193 353-573 64 9.1e-165 558.48 Pfam 1-234 (234) Show / Hide 
Range on Protein: 353-573
Range on HMM: 1-234/234
Sequence Identity: 64% (151 aa)

FFISPANNICFYGECSYYCSTEHALCG--KPDQIEGSLAAFLPDLSLAKRKTWRNPWRRSYHKRKKAEWEVDPDYCEE-VKQTPPYDSSHRILDVMDMTI
||.|||||.||||.|||||.||||.||  .||..||||.|.||||||..||.||.||.|.||||||||||.||.||.. |||.||||. .|.||..||.|
FFCSPANNTCFYGKCSYYCKTEHAVCGDQNPDMMEGSLTAWLPDLSLWPRKKWRHPWQRTYHKRKKAEWETDPNYCDTYVKQMPPYDHGTRLLDIIDMAI

FDFLMG-------NMDRHHYETFEKFGNETFIIHLDNGRGFGKYSHDELSILVPLQQCCRIRKSTYLRLQLLAKEEYKLSLLMAESLRGD---QVAPVLY
||||.|       ||||||||||||||||||.||||||||||..|||||||| ||.|||.||.||.|||||.....|.|| .|.|||. |   .|.|||.
FDFLIGRFFSVGHNMDRHHYETFEKFGNETFLIHLDNGRGFGNHSHDELSILAPLYQCCMIRRSTWLRLQLFSNPGYRLSEVMRESLSHDPLHPVHPVLT

QPHLEALDRRLRVVLKAVRDCVERNGLHSVVDDD
.||.||.||||..|. .|..|.|..|. .|. .|
EPHYEAMDRRLQIVMQTVEQCIEQHGRDDVIVED