MAST_b-1

Species: S.moellendorffii
Alias: MAST_b-1
External Links:
Annotation:

Classification

Group: AGC
Family: MAST
Subfamily: MAST

Sequence

Name Sequence Type Origin Length Description Download
MAST_b-1.AA Protein None 756 None Fasta, JSON
MAST_b-1.NA RNA None 2271 None Fasta, JSON
MAST_b-1.kin_dom Protein Kinase Domain None 273 None Fasta, JSON

Protein domain

Protein domains of MAST_b-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MAST_b-1.AA AGC 408-680 32 4.7e-176 459.82 In-house 1-395 (395) Show / Hide
Range on Protein: 408-680
Range on HMM: 1-395/395
Sequence Identity: 32% (129 aa)

FEIIKPISRGAFGRVFLARKK------TTGDLFAVKVLRKSD---MIRKNAVRSVQAE------------RNILISAR----------NPFVVR-FFYSF
||..|.|..|.||.|.|.|||      .||...|.|||.|..   ...|| |. ...|            ||||  ..          .||.|.  .|||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

TCSEN--LYLVMEYLN--------GGDLYSLLMSMG-----CLEEDMARVYIAE-------LVLALEYLHS-LGVVHRD-LKPGNILIAHDGHIKLTDFG
   ..  ||.||||..        ||.. ..|. .|     ...|..|| |.||       .||||||||| .|..||| ||| |||. .||||||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSRMGLINS---------------------------TDDLAIAMNDDR----------EHNQLKSAVG--TPDYLAPEILLGTEHDHAADWWS--VGIIL
|. .|  .                            .   .  .....          .... .. .|  ||.|.|||||    ...|.||||  .|...
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNK-CNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLM

YEFLTGVPPFNAEHPQ----------IIFDNIL------NKKISWPRVP-------EDVSYDAYDLINRLLTDDPKRRLGYR-------GAGEVKAHPFF
||.||| |||... ||           .|..|.      |.|. .|.         . .| .| |||..||. ||..|||..       || |.|.||.|
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF





Kinase MAST_b-1.AA MAST 408-680 43 1.5e-167 516.5 In-house 1-337 (337) Show / Hide
Range on Protein: 408-680
Range on HMM: 1-337/337
Sequence Identity: 43% (147 aa)

FEIIKPISRGAFGRVFLARKKTTGDLFAVKVLRKSDMIRKNAVRSVQAERNILISARNPFVVRFFYSFTC--SENLYLVMEYLNGGDLYSLLMSMG-CLE
||.||.||.||.|.|.|...|.|.|.|| ||....|.|.|| | .|..|||||  . ||||| .||||     . |..||||..|||  ||| ..| |..
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

EDMARVYIAELVLALEYLHSLGVVHRDLKPGNILIAHDGHIKLTDFGLSRMGLINSTDDLAIA--------------MNDDREHNQL-------------
|.||. ||||.||.|||||| | ||||||| |.||  .||||||||||| .|... |  ...                . ... .|.             
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDKTTNHYEGYFNTNIFGKNHFNEYHIQKNYQQFQQDFGINGNTNKN

-------------------------KSAVGTPDYLAPEILLGTE-HDHAADWWSVGIILYEFLTGVPPFNAEHPQ-IIFDNILN--KKISWPRV-----P
                         |. .|||||.|||..||.  .  ..||||.|||.||||.|.||||.. |. .||.||.|  ..|.|| .      
QIQQQQEQPQCQQQNEMRPHNIHQNKQCCGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDD

EDVSYDAYDLINRLLTDDPKRRLGYRGAGEVKAHPFF
. .| .|.|||..||. .|| ||| .|| |.| ||||
DCMSPEAQDLIKKLLQPNPKKRLGANGADEIKQHPFF

Kinase MAST_b-1.AA MAST 408-680 47 4.1e-162 526.66 In-house 1-334 (334) Show / Hide
Range on Protein: 408-680
Range on HMM: 1-334/334
Sequence Identity: 47% (158 aa)

FEIIKPISRGAFGRVFLARKKTTGDLFAVKVLRKSDMIRKNAVRSVQAERNILISARNPFVVRFFYSFTCSENLYLVMEYLNGGDLYSLLMSMGCLEEDM
||.|||||.||.|.|.|...|.|.|.||.||..|||||.|| | .||.|||||  ..||||| .||||   ..|..||||..|||. ||| ..|...|.|
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

ARVYIAELVLALEYLHSLGVVHRDLKPGNILIAHDGHIKLTDFGLSRMGLIN-----------------STDDLAIAMNDDREHN---------------
|. ||||.||.|||||| | ||||||| |.||  .||||||||||| .|...                 |||. .  ..|...                 
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDDLNMMYEGYTPPNIFNNSTDPMNKNQQDYSQFPGDFGINGNTNKNQIQ

-------------------QLKSAVGTPDYLAPEILLGTE-HDHAADWWSVGIILYEFLTGVPPFNAEHPQIIFDNILNKK---ISWPRV-----PEDVS
                   | |. .|||||.|||..||.  |  . ||||.|||.||||.|.|||| . |..||.||||..   |.|| .      |  |
QQQEQPQCQQQNMRPHNIHQNKQCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMS

YDAYDLINRLLTDDPKRRLGYR-GAGEVKAHPFF
 .|.|||..||. ||. ||| . || ||| ||||
PEAQDLIEKLLQPDPRKRLGANNGADEVKQHPFF

Kinase MAST_b-1.AA NDR 408-680 39 1.1e-152 474.73 In-house 1-350 (350) Show / Hide
Range on Protein: 408-680
Range on HMM: 1-350/350
Sequence Identity: 39% (139 aa)

FEIIKPISRGAFGRVFLARKKTTGDLFAVKVLRKSDMIRKNAVRSVQAERNILISAR--NPFVVRFFYSFTCSENLYLVMEYLNGGDLYS---LLMSMGC
|||||.|..||||.|.|.||| ||...|.|..|||.|..|| | .|.||| |. .|.  ||.||. .|||  . .|||||||. |||. .   ||| |..
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI

LEEDMARVYIAELVLALEYLHSLGVVHRDLKPGNILIAHDGHIKLTDFGLSRMGLI--------------------------------NSTDDLAIAMND
..||.|| ||||.|.|.|..|..| .|||.|| |.||  |||||||||||...|.|                                . . .  .....
FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLCTGGMIRRHWKQNKQKKPMTTYSTFHWTHNSWYYQNMKEHRPQDFMDNWN

DREHNQLK-------------------------------SAVGTPDYLAPEILLG-TEHDHAADWWSVGIILYEFLTGVPPFNAEHPQIIFDNILNKKIS
.   ||..                               |.||||||.|||.... |..... ||||.| |.||.|.|.|||... || ....|.| |. 
SNPMNQKCKCHTQMKDQMKCNVKVLNNRSWKQNRRCLAYSTVGTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQT

WP----RVPEDV--SYDAYDLINRLLTDDPKRRLGY--RGAGEVKAHPFF
|.     .|...  | .| ||| ||.. ||..|||    |. |.|.||||
WDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGKGVDEIKSHPFF

Kinase MAST_b-1.AA S_TKc 408-680 33 5.4e-109 369.32 SMART 1-231 (231) Show / Hide
Range on Protein: 408-680
Range on HMM: 1-231/231
Sequence Identity: 33% (97 aa)

FEIIKPISRGAFGRVFLARKKTTGDLFAVKVLRKSDMIRKNAVRSVQAERNILISARNPFVVRFFYSFTCSENLYLVMEYLNG--GDLYSLLMSMGC---
.||...| .||||.|...|.| || ..|.|...          .... |..|| . . |..|.....|   ..||.||||..|  |||.... ..|.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LEEDMARVYIAELVLALEYLHSLGVVHRDLKPGNILIAHDGHIKLTDFGLSRMGLINSTDDLAIAMNDDREHNQLKSAVGTPDYLAPEILLGTEHDH
   . | .|| |......||||.||.|..|||||| |||. .  |||..||||.|                       .. .|||.|.|||.|    ...
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------------------TTFCGTPWYMAPEVL---GYGK

-AADWWSVGIILYEFLTGVPPFNAEHPQIIFDNILNKKISWPRVPEDVSYDAYDLINRLLTDDPKRRLGYRGAGE----VKAHPFF
 ..||||.|.||||.|.| |||   ..| .|..|.             | .| |.|...|. ||..|..   | .    .|.||.|
CKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase MAST_b-1.AA RSK 411-680 39 4.5e-106 358.69 In-house 1-278 (278) Show / Hide
Range on Protein: 411-680
Range on HMM: 1-278/278
Sequence Identity: 39% (116 aa)

IKPISRGAFGRVFLARKK---TTGDLFAVKVLRKSDMIRKNA-VRSVQAERNILISAR-NPFVVRFFYSFTCSENLYLVMEYLNGGDLYSLLM---SMGC
.|   .|..| ||| ||.    || ..|.|||.|. .....  .| . .|||||   .  ||.|. .|.|   . |||.|||..||.|.  |    ..||
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LEEDMARVYIAELVLALEYLHSLGVVHRDLKPGNILIAH---DGHIKLTDFGLSRMGLINSTDDLAIAMNDDREHNQ-LKSAVGTPDYLAPEILL----G
. || |..|.||.|||.|.||..|..|||||| ||| ..   .|||||||||... .              . .||| ... ..| .|.|||.|     .
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF--------------RCDHNQWTMTFCYTIEYMAPEMLKRANQQ

TEHDHAADWWSVGIILYEFLTGVPPFNA---EHPQIIFDNILNKKISWPRVP--EDVSYDAYDLINRLLTDDPKRRLG--YRGAGEVKAHPFF
  ||.|.|||| |...|| ||| ||| .   .... |...|...|.| .. |  . .| .| |||...|. ||..|||   ..| |.|.||.|
GGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFS-LTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF

Kinase MAST_b-1.AA MASTL 408-680 40 1.8e-102 346.76 In-house 1-283 (283) Show / Hide
Range on Protein: 408-680
Range on HMM: 1-283/283
Sequence Identity: 40% (122 aa)

FEIIKPISRGAFGRVFLA-RKKTTGDLFAVKVLRKSDMIRKNAVRSVQAERNILISARNPFVVRFFYSFTCSENLYLVMEYLNGGDLYSLLMSMGCLEED
| |.|||||||||.|.|  . .  . |.||||..|.||| || .  |||||. |   . .|.|  .||     ..||||||. |||. |||   |   |.
FVIVKPISRGAFGKVYLGYKNQKGKKLYAVKVMKKADMINKNMTHQVQAERDALALSKSQFCVHLYYSLQSASYVYLVMEYMIGGDVKSLLHMYGYFDEE

MARVYIAELVLALEYLHSLGVVHRDLKPGNILIAHDGHIKLTDFGLSRMGLINSTDDLA--IAMNDDREHNQLKSAVGTPDYLAPEILLGTEHDHAADWW
||. ||.|.|.||.|||  |..|||.|| |.||  .|||||||||||.. .     |.   ..| |           ||||||.|| ..   |  . |||
MAIKYISEMVMALDYLHRHGIIHRDIKPDNMLISNEGHIKLTDFGLSKVTMNR---DINARVSMMD---------ILGTPDYLKPEQDYQQTHGQVVDWW

S-VGIILYEFLTGVPPFNAEHPQIIFDNILNKKISWPRVPEDVS---------------------YDAYDLINRLLTDDPKRRLGYRGAGEVKAHPFF
.  |. .|||..|.|||. | |.  |.|||.. ..||   | .|                       . .|| .||. .|. |     | .|. | | 
ASLGVCFYEFMKGIPPFCDESPCKVFQNILSRDLEWPMGDEQKSTTPYSSKLLKSCFETVASNPEVPVMCLIENLLQMRPRDR---PSATDVQQHTFI

Kinase MAST_b-1.AA AktR 408-680 38 1.5e-99 336.99 In-house 1-268 (268) Show / Hide
Range on Protein: 408-680
Range on HMM: 1-268/268
Sequence Identity: 38% (107 aa)

FEIIKPISRGAFGRVFLARKK-TTGDLFAVKVLRKSDMIRKNAVRSVQAERNILI-SARNPFVVRFFYSFTCSENLYLVMEYLNGGDLYSLLMSMGCLEE
|...|.. .||||.|.|..|| ......| |...|...|..|. . .. ||||..  ...|| |...|.|   |.|...|||  ||.|.. | . . ..|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

DMARVYIAELVLALEYLHSL-GVVHRDLKPGNILIAHDGHIKLTDFGLSRMGLINSTDDLAIAM-NDDREHNQLKSAVGTPDYLAPEILLG-TEHDHAAD
..|| |.|. .|||||||.   .. ||||| |||.  |||.|.||||||.         | . | .|....    | .||| |.|||...    |. ..|
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK---------LQFMMHYDEKAY----SFCGTPEYMAPEMITKKKGHNKSVD

WWSVGIILYEFLTGVPPFNAEHPQIIFDNILNKKISWPRVPEDVSYDAYDLIN-RLLTDDPKRRLG--YRGAGEVKAHPFF
||..|| .|| .|| |||...  ...|..|..| .  .  |...|  . |||. .|| ..|. |||    |. |.| ||.|
WWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF

Kinase MAST_b-1.AA Pkinase 408-680 28 5.2e-89 306.82 Pfam 1-293 (293) Show / Hide
Range on Protein: 408-680
Range on HMM: 1-293/293
Sequence Identity: 28% (90 aa)

FEIIKPISRGAFGRVFLARKKTTGDLFAVKVLRKSDMIRKNAVRSVQ-AERNILISARNPFVVRFFYSFTCSENLYLVMEYLNGG----DLYSLLM--SM
..|...| .|.||.|.....| ||...|||...|..   .  .. .  .|  |. . . |..||....|. . ..|.||||..||    ||.....  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GCL--EEDMARVYIAELVLALEYLHSLGVVHRDLKPGNILIAHDGHI----KLTDFGLSRMGLINSTDDLAIAMNDDREHNQLKSAVGTPDYLAPEILL-
||.  .|. .. |. ... .|||.|| |..|||||| |||| ..|||    |..||||..                      ... .|||.|.|||... 
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-------------Y-NNS-MTTFCGTPWYMAPEVIRG

GTEHDHAADWWSVGIILYEFLTGVPPFNAE------HPQIIFDNILNKKISWPRVPE-DVS-----------------YDAYDLINRLLTDDPKRRLGYR
|.......|.||.|.||||.|.| |||  .       .. ....|. .......  . ..|                  .. |.|...|. |||.|..  
GQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT--

GAGEVKAHPFF
 | ... ||.|
-AEQILQHPWF

Kinase MAST_b-1.AA Akt 408-558 47 2.6e-76 243.45 In-house 1-153 (264) Show / Hide
Range on Protein: 408-558
Range on HMM: 1-153/264
Sequence Identity: 47% (73 aa)

FEIIKPISRGAFGRVFLARKKTTGDLF-AVKVLRKSDMIRKNAVRSVQAERNILISARNPFVVRFFYSFTCSENLYLVMEYLNGGDLYSLLMSMGCLEED
|...| . .|.||.|||..|| |.... | |||.|.  | || |. ...|||||   ..||.|   |||  ...||.||.| |||.|...|   .   ||
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

MARVYIAELVLALEYLHSLGVVHRD-LKPGNILIAHDGHIKLTDFGLSRMGLI
 || |.||..||.|.||| ... || ||| |||. .||||.||||||.....|
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENII

Kinase MAST_b-1.AA SGK 408-553 38 2.9e-70 216.02 In-house 1-172 (283) Show / Hide
Range on Protein: 408-553
Range on HMM: 1-172/283
Sequence Identity: 38% (66 aa)

FEIIKPISRGAFGRVFLARKKTT------------------GDLFAVKVLRKSDMI-------RKNAVRSVQAER-NILISARNPFVVRFFYSFTCSENL
|...| |  | ||.|.....| .                  ....|.|||.|   |       .|. .. ..||| .||   . || |   |.|   . |
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YLVMEYLNGGDLYSLLMSMGCLEEDMARVYIAELVLALEYLHSLGVVHRDLKPGNILIAHDGHIKLTDFGLS
|.||.|.|||.. . |   ... || || | ||.|.|||||||. ...||||| |||  |.||..||||||.
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLC

Kinase MAST_b-1.AA PKA 408-551 46 7.1e-64 218.53 In-house 1-146 (263) Show / Hide
Range on Protein: 408-551
Range on HMM: 1-146/263
Sequence Identity: 46% (68 aa)

FEIIKPISRGAFGRVFLARKKTTGDLFAVKVLRKSDMIRKNAVRSVQAERNILISARNPFVVR-FFYSFTCSENLYLVMEYLNGGDLYSLLMSMGCLEED
||||. . .| |||| |.|.|..|. .| |.|.|.. .| . |  |  |.||| . ..||.|.   ..| .. .||.|||| .||.. | |.  |.. ..
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

MARVYIA-ELVLALEYLHSLGVVHRDLKPGNILIAHDGHIKLTDFG
.|. |.| . |||||||||.  ..||||| ||||  .||||.||||
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFG

Kinase MAST_b-1.AA SGK 582-680 48 4.3e-47 143.19 In-house 187-283 (283) Show / Hide
Range on Protein: 582-680
Range on HMM: 187-283/283
Sequence Identity: 48% (48 aa)

GTPDYLAPEILLGTEHDHAADWWSVGIILYEFLTGVPPFNAEHPQIIFDNILNKKISWPRVPEDVSYDAYDLINRLLTDDPKRRLGYR-GAGEVKAHPFF
||| |||||.|.. .|| . |||. |..|||...| |||     |. .|||.|...   . |  .| || |||. ||. ||| ||| . ...|.| ||||
GTPEYLAPEVLRKQPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPL---QIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF





Kinase MAST_b-1.AA Akt 578-680 43 4.8e-43 135.39 In-house 160-264 (264) Show / Hide
Range on Protein: 578-680
Range on HMM: 160-264/264
Sequence Identity: 43% (46 aa)

KSAVGTPDYLAPEILLGTEHDHAADWWS-VGIILYEFLTGVPPFNAEHPQIIFDNILNKKISWPRVPEDVSYDAYDLINRLLTDDPKRRLG--YRGAGEV
|.  ||| |||||||.|. |. |.|||. .|...||...| ||| ..  .  |..|.|...  |.  . .| .. |||..||. |||.|||  . .| |.
KTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYNQDHHQMFKKIKNQPVKFPDK-DWISPECKDLISGLLNKDPKKRLGGGPNDAQEI

KAHPFF
|.||.|
KRHPWF

Kinase MAST_b-1.AA PKA 582-680 41 1.4e-31 111.26 In-house 160-263 (263) Show / Hide
Range on Protein: 582-680
Range on HMM: 160-263/263
Sequence Identity: 41% (44 aa)

GTPDYLAPEILLGT-EHDHAADWWSVGIILYEFLTGVPPFNAE--HPQIIFDNILNKKISWPRVPEDVSYDA---YDLINRLLTDDPKRRLG--YRGAGE
|||.||||||....  |  . |||. ||. ||.|.|.|||...   |  |.. |.| || .||    .. ||    |||..||. |...|.|    |.  
GTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFYDHNRDPMQIYEKICNGKIKFPR---HFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVND

VKAHPFF
.| |..|
IKNHKWF

Kinase MAST_b-1.AA Pkinase_Tyr 408-554 29 8.3e-21 71.09 Pfam 1-159 (270) Show / Hide
Range on Protein: 408-554
Range on HMM: 1-159/270
Sequence Identity: 29% (47 aa)

FEIIKPISRGAFGRVFLARKK----TTGDLFAVKVLRKSDMIRKNAVRSVQAERNILISA-RNPFVVRFFYSFT-CSEN--LYLVMEYLNGGDLYSLLMS
 ...| . .||||.|.... |     |.   |||.|. . | . |  ..  .| .|. .  ..| .||.    |  .|   .|.||||  .|||.. | .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

M----GCLEEDMARVYIAELVLALEYLHSLGVVHRDLKPGNILIAHDGHIKLTDFGLSR
     . |   .   . ..   ..|||.| . .||||   |.|.......| .||||.|
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR

Kinase MAST_b-1.AA TyrKc 408-680 21 1.8e-15 27.4 SMART 1-280 (280) Show / Hide
Range on Protein: 408-680
Range on HMM: 1-280/280
Sequence Identity: 21% (66 aa)

FEIIKPISRGAFGRVFLARKKTTGDLFAVKVLRKSDMIRKNAVRSVQAERNILISA--RNPFVVRFFYSFTCS-------ENLYLVMEYLNGGDLYSLLM
 . .| . .||||.|.... |      |||.|...       ..    | .|. .   ..| .||..   | .       | |..||||  .||| . | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

SMGC-LEEDMARVYIAELVLALEYLHSLGVVHRDLKPGNILIAHDGHIKLTDFGLSRMGLIN-STDDLAIAMNDDREHNQLKSAV--GTPD-----YLAP
. .  |  .    .        ||||| ...||||   |.|.......| .|||||| .    ..           ..   ...   |. .      .||
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG---------ESKDYYRKKEHKGGKTMLPIRWMAP

EILLGTEHDHAADWWSVGIILYEFLT-GVPPFNA-----EHPQIIFDNILNKKISWPRVPED--------VSYDAYDLINRLLTDDPKRRLGYRGAGEVK
| .   .  .. | || |. ..| .| | .|          .| .. .. . .   .  |..         . . |... .    ||. |   .      
ECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQ--PPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI----

AHPFF
 | .|
-HECF