Gene RSK-p1-S1-1 (S.moellendorffii)
RSK-p1-S1-1
Species: S.moellendorffii
Alias: RSK-p1-S1-1
External Links:
Annotation:
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
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RSK-p1-S1-1.AA | Protein | None | 176 | None | Fasta, JSON |
RSK-p1-S1-1.NA | RNA | None | 531 | None | Fasta, JSON |
RSK-p1-S1-1.kin_dom | Protein Kinase Domain | None | 123 | None | Fasta, JSON |
Protein domains of RSK-p1-S1-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | RSK-p1-S1-1.AA | AGC | 1-123 | 32 | 5.2e-87 | 224.25 | In-house | 192-395 (395) | Show / Hide |
Range on Protein: 1-123 Range on HMM: 192-395/395 Sequence Identity: 32% (68 aa) GHVKLTDFGLAKKAILDN--------------------------------------------------KSASTFCG--TPEYIAPEILCNSGHGRAADWW ||.|||||||.|. . |. . ..|||| ||||.||||| .|.|.||| GHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWW S--LGTLLYEMLCGLPPFYHKNVN----------IMYDRIL------NAKLTFP----------AFLTPVARDLLSKLLVRNPETRLGAGQRD-----YE | || |.||||.|.||||..|.. |...|. | |..|| ...| |.||..|||...|| |||.|..| .| SFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAE EIIEHQFF || .| .| EIKNHPWF |
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Kinase | RSK-p1-S1-1.AA | SGK | 1-123 | 52 | 2.5e-74 | 228.82 | In-house | 162-283 (283) | Show / Hide |
Range on Protein: 1-123 Range on HMM: 162-283/283 Sequence Identity: 52% (64 aa) GHVKLTDFGLAKKAILDNKSASTFCGTPEYIAPEILCNSGHGRAADWWSLGTLLYEMLCGLPPFYHKNVNIMYDRILNAKLTFPAFLTPVARDLLSKLLV ||..||||||.| | .|. .|||||||| |||.| .|.|. |||.||..||||. ||||||..|...||| |.| .| .| . .. |.||. || GHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQ RNPETRLGAGQRDYEEIIEHQFF ..|. |||. || .|| .|.|| KDPKKRLGT-KRDFMEIKNHPFF |
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Kinase | RSK-p1-S1-1.AA | Akt | 1-123 | 48 | 2.8e-74 | 236.82 | In-house | 138-264 (264) | Show / Hide |
Range on Protein: 1-123 Range on HMM: 138-264/264 Sequence Identity: 48% (62 aa) GHVKLTDFGLAKKA-ILDNKSASTFCGTPEYIAPEILCNSGHGRAADWWS-LGTLLYEMLCGLPPFYHKNVNIMYDRILNAKLTFP--AFLTPVARDLLS ||..||||||.|. | |. . ||||||||.||||| . ||..|.|||. || ..|||.||.||||.... |.. |.|... || .. | ..||.| GHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLIS KLLVRNPETRLGAGQRDYEEIIEHQFF .|| ..|. |||.| | .|| .| .| GLLNKDPKKRLGGGPNDAQEIKRHPWF |
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Kinase | RSK-p1-S1-1.AA | RSK | 1-123 | 47 | 1.1e-58 | 201.33 | In-house | 144-278 (278) | Show / Hide |
Range on Protein: 1-123 Range on HMM: 144-278/278 Sequence Identity: 47% (64 aa) GHVKLTDFGLAKKAILD-NKSASTFCGTPEYIAPEILC----NSGHGRAADWWSLGTLLYEMLCGLPPFYH---KNVNIMYDRILNAK--LTFP--AFLT ||.||||||..|.. .| |. . |||.| ||.|||.| ..||..|.|||||| |.|||| | |||.. .| . .||...| ||.| ..|. GHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLS PVARDLLSKLLVRNPETRLGAGQRDYEEIIEHQFF . |.||..|.| |.|. |||.| .| ||| .|..| QEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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Kinase | RSK-p1-S1-1.AA | p70 | 1-123 | 50 | 2.2e-55 | 190.34 | In-house | 165-299 (299) | Show / Hide |
Range on Protein: 1-123 Range on HMM: 165-299/299 Sequence Identity: 50% (68 aa) GHVKLTDFGLAKKAILDNKS----------ASTFCGTPEYIAPEILCNSGHGRAADWWSLGTLLYEMLCGLPPFYHKNVNIMYDRILNAK--LTFPAFLT |||.|||||| |. | | . |||||.|| ||||| .||..| |||||| |.| || | ||| | | || .| |. |. || GHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCGTIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLT PVARDLLSKLLVRNPETRLGAGQRDYEEIIEHQFF . .|||. ||| |.| .|.||| | ..| ||.|| HEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF |
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Kinase | RSK-p1-S1-1.AA | AktR | 1-123 | 43 | 2.3e-55 | 190.26 | In-house | 139-268 (268) | Show / Hide |
Range on Protein: 1-123 Range on HMM: 139-268/268 Sequence Identity: 43% (57 aa) GHVKLTDFGLAK--KAILDNKSASTFCGTPEYIAPEILCN-SGHGRAADWWSLGTLLYEMLCGLPPFYHKNVNIMYDRILNAK---LTFPAFLTPVARDL ||||.|||||.| . . .. | .|||||||.|||.. . ||....|||..|...|||. |.||||||| |.|...|.. ..|. ... ..|| GHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDL LS-KLLVRNPETRLGAGQRDYEEIIEHQFF . ||| .||. ||| . . ||| .| .| IQRKLLCKNPNKRLGYYCNGWEEIKSHPWF |
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Kinase | RSK-p1-S1-1.AA | PKC | 1-123 | 38 | 2.8e-55 | 177.55 | In-house | 137-262 (262) | Show / Hide |
Range on Protein: 1-123 Range on HMM: 137-262/262 Sequence Identity: 38% (48 aa) GHVKLTDFGLAKKAILDNKSASTFCGTPEYIAPEILCNSGHGRAADWWSLGTLLYEMLCGLPPFYHKNVNIMYDRILNAKLTFPAFLTPVARDLLSKLLV ||.|..|||..| ... . .|||||||.||||||| | . |||..| |.|||..| .|| .. . . |.. . .| |. | ....... GHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPFHGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMT RNPETRLGAGQRD---YEEIIEHQFF .|||.|||..... ..| ||.|| KNPEKRLGCHPQQEEGEQDIREHPFF |
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Kinase | RSK-p1-S1-1.AA | RSK | 1-123 | 42 | 1.8e-54 | 187.26 | In-house | 142-271 (271) | Show / Hide |
Range on Protein: 1-123 Range on HMM: 142-271/271 Sequence Identity: 42% (55 aa) GHVKLTDFGLAKKAILDNKSASTFCGTPEYIAPEILCNSGHGRAADWWSLGTLLYEMLCGLPPFYHKNVNIMYDRILNAKLTF-------PAFLTPVARD ||.|..|||.||... .|. . |||.| .|.|||.| ||..|.||||.|.|.|||| | .||..|. . . . |...|| ..|... | | GHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEMLTGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKD LLSKLLVRNPETRLGAGQRDYEEIIEHQFF ||...| |.|. ||||| . |.| .| .| LLRMMLHRDPHNRLGAGPNGVEQIKQHPWF |
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Kinase | RSK-p1-S1-1.AA | PKA | 1-123 | 44 | 9.4e-53 | 181.58 | In-house | 138-263 (263) | Show / Hide |
Range on Protein: 1-123 Range on HMM: 138-263/263 Sequence Identity: 44% (57 aa) GHVKLTDFGLAKKAILDNKSASTFCGTPEYIAPEILCNS-GHGRAADWWSLGTLLYEMLCGLPPFYHK--NVNIMYDRILNAKLTFPAFLTPVA---RDL ||.|.|||| ||| .|. .| ||||||.||||. .. |||.. |||.|| | |||| | |||| . ... .|..|.|.|. || .... | .|| GHIKITDFGFAKK--VDD-RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDL LSKLLVRNPETRLGAGQRDYEEIIEHQFF ..|||..... |.| . . . | .| .| IKKLLQVDLTKRYGNMKNGVNDIKNHKWF |
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Kinase | RSK-p1-S1-1.AA | RSK-Unclassified | 1-123 | 39 | 9.2e-50 | 154.21 | In-house | 138-283 (283) | Show / Hide |
Range on Protein: 1-123 Range on HMM: 138-283/283 Sequence Identity: 39% (58 aa) GHVKLTDFGLAKKA--------------------ILDNKS-ASTFCGTPEYIAPEILCNSGHGRAADWWSLGTLLYEMLCGLPPFYHKNVNIMYDRILNA |||.||||.| ..| |.| . . |||| ||.|||.. ||..| ||| || ..|||| |.||.| | | .. |. . GHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGHTKAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKN KLTFP--AFLTPVARDLLSKLLVRNPETRLGAGQRDYEEIIEHQFF .. || .. .|||. ||| ||| |||... | ..| |.|| HVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF |
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Kinase | RSK-p1-S1-1.AA | Pkinase | 1-123 | 30 | 2.7e-41 | 147.09 | Pfam | 145-293 (293) | Show / Hide |
Range on Protein: 1-123 Range on HMM: 145-293/293 Sequence Identity: 30% (48 aa) GHV----KLTDFGLAKKA-ILDNKSASTFCGTPEYIAPEILC-NSGHGRAADWWSLGTLLYEMLCGLPPFYHK------NVNIMYDRILNAKLTFPAFLT ||. |..||||||.. . | ..||||||.|.|||.. ....|...|.||.| .||||||| |||... . . |..||. ..| |. . . GHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWW ---------------------PVARDLLSKLLVRNPETRLGAGQRDYEEIIEHQFF . ..|.....| ..|. |.. |.| .| .| CSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQHPWF |
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Kinase | RSK-p1-S1-1.AA | S_TKc | 1-123 | 19 | 4.3e-10 | -28.96 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 1-123 Range on HMM: 1-231/231 Sequence Identity: 19% (49 aa) G--------------------------------------------------------------------------------------------------- YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPEHARFYM -----------------------------HVKLTDFGLAKKAILDNKSASTFCGTPEYIAPEILCNSGHGR-AADWWSLGTLLYEMLCGLPPFYHKNVNI |.|..|||||.. .||||||.|.|||.| |.|. ..||||.| .||||||| |||. ... YQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQM MYDRILNAKLTFPAFLTPVARDLLSKLLVRNPETRLGAGQRDY--EEIIEHQFF |...|. .| |.|...|.|...|| |..| . ..| |..| MFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | RSK-p1-S1-1.AA | S_TK_X | 124-176 | 20 | 2.7e-07 | 31.46 | SMART | 1-79 (79) | Show / Hide |
Range on Protein: 124-176 Range on HMM: 1-79/79 Sequence Identity: 20% (17 aa) ASVNWTSMLQ--KKIRPPFVPQVK----AADDVGNFDVVFTCEQITTTVWYADQ---------------------FIG---ER ....| .. |.| |||.|..| . |..||| || |... . .. |.| . RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM----LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF |
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Kinase | RSK-p1-S1-1.AA | Pkinase_C | 143-166 | 45 | 0.000329 | 18.15 | Pfam | 1-24 (46) | Show / Hide |
Range on Protein: 143-166 Range on HMM: 1-24/46 Sequence Identity: 45% (11 aa) QVKAADDVGNFDVVFTCEQITTTV ||| ..|. |||. ||.| . |. QVKSPTDTSNFDPEFTDEPPMDTP |