Gene RSK-p3_e-1 (S.moellendorffii)

RSK-p3_e-1

Species: S.moellendorffii
Alias: RSK-p3_e-1
External Links:
Annotation:

Classification

Group: AGC
Family: RSK
Subfamily: RSK-p3

Sequence

Name Sequence Type Origin Length Description Download
RSK-p3_e-1.AA Protein None 567 None Fasta, JSON
RSK-p3_e-1.NA RNA None 1704 None Fasta, JSON
RSK-p3_e-1.kin_dom Protein Kinase Domain None 322 None Fasta, JSON

Protein domain

Protein domains of RSK-p3_e-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase RSK-p3_e-1.AA AGC 47-368 25 3.7e-132 343.71 In-house 1-395 (395) Show / Hide 
Range on Protein: 47-368
Range on HMM: 1-395/395
Sequence Identity: 25% (112 aa)

FRIIKSIGHGDMGTVFLVALR------GDNSPYAMKVMKKEV-LAARE--NFHRAQTE------------KEILKALD----------HPFLPR-LLAHF
|...| || |  |.|.||  .      . .  |||||.||..    ..    ....||            ..||. ..          |||. . |   |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

ETDKH--TFLVTDYCC--------GGDLNVLRQKQ---PDKRFSESATRFYAAE-------VLLALEYLHE-HGIIYRD-LKPENILIKENGHVMLTDFD
....|   ..| .|..        ||..  . ..|     .||.|...||||||       ..|||||||. .|||.|| |||||||. |.||..|||| 
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSLNLA--------------TKKKTSSSSSSPLFTDKKKKPSKPRRLSCGLHFELPRIITQRRKNTSKSCKKAVARIFPRSCGSSSDCRSN---------
|.  .               ... ...   . .  ... . .                                     . |. ..  | |         
LCKEGMNDGEKGQQSQSNMKFHW-HNKKY-Q-KS-NMD-T-N-------------------------------------K-CNPNNWQRNNMSQEDDTTR

-------SFVG--TEEYVAPEVVWGSGHGLPVDWWT--FGVFLYELVYAKTPFKGSR----------RKDTFYNIL------CKEVELPGP---------
       .|.|  | ||.|||..    .| ..|||.  .|...||... ..|| |            ....| .|.       ..|..| |         
KKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDR

--PTPLKDLIAGLLVKDPEQRLGSRQ------GALEVRNHAFF
     .|||| .||.||||.|||...      || |..|| .|
WFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase RSK-p3_e-1.AA AktR 47-368 34 8.1e-98 331.28 In-house 1-268 (268) Show / Hide 
Range on Protein: 47-368
Range on HMM: 1-268/268
Sequence Identity: 34% (115 aa)

FRIIKSIGHGDMGTVFLVALR-GDNSPYAMKVMKKEVLAARENFHRAQTEKEILK-ALDHPFLPRLLAHFETDKHTFLVTDYCCGGDL-NVLRQKQPDKR
|...| .| |  |.|.||  .  ..  ||||. ||. .  |. .|...||. |..   .|||. .|   |.|... |.. .||.||.| ..|..|   |.
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKK---KK

FSESATRFYAAEVLLALEYLHEH-GIIYRDLKPENILIKENGHVMLTDFDLSLNLATKKKTSSSSSSPLFTDKKKKPSKPRRLSCGLHFELPRIITQRRK
|||. .|||.|..||||||||.|  ||||||||||||. |.||| .||| ||                                                
FSEEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK-----------------------------------------------

NTSKSCKKAVARIFPRSCGSSSDCRSNSFVGTEEYVAPEVVWG-SGHGLPVDWWTFGVFLYELVYAKTPFKGSRRKDTFYNILCKE-VELPGPPTP---L
                    . | . .||.|| ||.|||..    ||. .||||.||.|.||.|.  .||  . ... | .|. |. .. | |. .   .
---------------LQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQC

KDLIA-GLLVKDPEQRLG-SRQGALEVRNHAFF
||||  .|| |.|..||| .. |. |...| .|
KDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase RSK-p3_e-1.AA RSK 50-368 30 9.2e-86 291.23 In-house 1-278 (278) Show / Hide 
Range on Protein: 50-368
Range on HMM: 1-278/278
Sequence Identity: 30% (103 aa)

IKSIGHGDMGTVFLVALR---GDNSPYAMKVMKKEVLAAREN-FHRAQTEKEILKALD-HPFLPRLLAHFETDKHTFLVTDYCCGGDLNVLRQKQPDK-R
.|  | |. | |||.        .  ||||| || ....|.    .. || .||..   |||. .|   |.|.....|...|| ||.|    ||.  .  
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FSESATRFYAAEVLLALEYLHEHGIIYRDLKPENILIKE---NGHVMLTDFDLSLN-LAT-KKKTSSSSSSPLFTDKKKKPSKPRRLSCGLHFELPRIIT
|||.  .||.||. ||.|.||..|||.|||||||||  .   .||..||||...    .  ...| .                                 
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMT---------------------------------

QRRKNTSKSCKKAVARIFPRSCGSSSDCRSNSFVGTEEYVAPEVVW----GSGHGLPVDWWTFGVFLYELVYAKTPFKG---SRRKDTFYNILCKEVELP
                                |..| ||.|||..     ..||.  .|||..|| .||.   ..||.|   . ||... .|. ..  |.
--------------------------------FCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLT

GP-----PTPLKDLIAGLLVKDPEQRLGS-RQGALEVRNHAFF
.|      .. |||| ..| .||..|||. .|.| |...|..|
MPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase RSK-p3_e-1.AA S_TKc 47-368 25 1.5e-85 291.42 SMART 1-231 (231) Show / Hide 
Range on Protein: 47-368
Range on HMM: 1-231/231
Sequence Identity: 25% (85 aa)

FRIIKSIGHGDMGTVFLVALRGDNSPYAMKVMKKEVLAARENFHRAQTEKEILKALDHPFLPRLLAHFETDKHTFLVTDYCCG--GDLNVLRQKQPDKR-
..|.. ||.| .|.|...  ....  .|.|..|           ... | .|||  .||.. .|. .|.. .| ..|..|| |  |||  . .|.. .. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FSESATRFYAAEVLLALEYLHEHGIIYRDLKPENILIKENGHVMLTDFDLSLNLATKKKTSSSSSSPLFTDKKKKPSKPRRLSCGLHFELPRIITQR
   |.|  .|||......||||.|.||||.|||||||||. |  |....|| |.  |                                           
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------------------------------------------

RKNTSKSCKKAVARIFPRSCGSSSDCRSNSFVGTEEYVAPEVVWGSGHGL-PVDWWTFGVFLYELVYAKTPFKGSRRKDTFYNILCKEVELPGPPTPLKD
                            ..|.|| .|.||||.   |.|  ..||| .|. |||... ..||      .. .....        . ..||
----------------------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG--------SPEAKD

LIAGLLVKDPEQRLGSRQGAL---EVRNHAFF
.| ..|.||||.|..  .      ....| .|
FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase RSK-p3_e-1.AA Ciliate-E2-Unclassified 47-368 20 3.1e-66 226.38 In-house 1-352 (352) Show / Hide 
Range on Protein: 47-368
Range on HMM: 1-352/352
Sequence Identity: 20% (84 aa)

FRIIKSIGHGDMGTVFLVALRGDNSPY-----AMKVMKKEVLAARENFHRAQTEKEILKA-------------------LDHPFLPRLLAHFETDKHTFL
..||| ||.|  |.|...  . ..  |     ..|.... ..  ...  .   |.....                    ..|||. ... .|..... ..
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VTDYCCGGDLNVLRQKQPD---------------KRFSESATR-----FYAAEVLLALEYLHEHG-IIYRDLKPENILIKENG---HVMLTDFDLSLNLA
|..|| ||||    .|..                |.|.| ...     ||.|..|..|||||. . ||.||.||||||...||   .. ..|| .| .. 
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

TK---KKTSSSSSSPLFTDKKKKPSKPRRLSCGLHFELPRIITQRRKNTSKSCKKAVARIFPRSCGSSSDCRSNSFVGTEEYV----APEVVWGSGHGLP
.    . |..                                            .          .  .......|.|| .|     ||||  | ... .
QNNNCD-TNQ--------------------------------------------Q-------QKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHS

----VDWWTFGVFLYELVYAKTPFKGSRRKD----------------TFYNILCKEVELPGPPT---------PLKDLIAGLLVKDPEQRLGSRQGALEV
    .|.|..|| |||... . ||..  ...                 . ||. |... |  |            ||.|  || |... ....| .. ..
KAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQI

RNHAFF
 || .|
LNHPWF
Kinase RSK-p3_e-1.AA RSK-Unclassified 47-194 44 1.2e-62 195.4 In-house 1-148 (283) Show / Hide 
Range on Protein: 47-194
Range on HMM: 1-148/283
Sequence Identity: 44% (66 aa)

FRIIKSIGHGDMGTVFLVALRGDNSPYAMKVMKKEVLAARENFHRAQTEKEILKALDHPFLPRLLAHFETDKHTFLVTDYCCGGDLNVLRQKQPDKRFSE
|  .. || ||.| |.||  .. .  |||||..|. .  .    .. ||..|.   .|||  .|   | |    .|. .|| |||.    |   .|.|.|
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

SATRFYAAEVLLALEYLHEHGIIYRDLKPENILIKENGHVMLTDFDLS
   ||||.|| .||||||  ..|||||||.||.    |||||||||||
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLS
Kinase RSK-p3_e-1.AA Akt 47-191 44 7.3e-52 164.03 In-house 1-145 (264) Show / Hide 
Range on Protein: 47-191
Range on HMM: 1-145/264
Sequence Identity: 44% (66 aa)

FRIIKSIGHGDMGTVFLVALRGDNSPY-AMKVMKKEVLAARENFHRAQTEKEILKALDHPFLPRLLAHFETDKHTFLVTDYCCGGDLNVLRQKQPDKRFS
|...| .| |  | ||||    ..  | |||| ||... ..  .  ..||. ||.  .|||.  |   | | .. ..|.||| ||.|  . |.  ..|||
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQR--KRRFS

ESATRFYAAEVLLALEYLHEHGIIYRD-LKPENILIKENGHVMLTDF
|. .|||.||. ||.|.||...||||| |||||||. ..||. ||||
EDRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDF
Kinase RSK-p3_e-1.AA SGK 47-205 36 1.3e-51 157.43 In-house 1-184 (283) Show / Hide 
Range on Protein: 47-205
Range on HMM: 1-184/283
Sequence Identity: 36% (67 aa)

FRIIKSIGHGDMGTVFLVALRGD------------------NSPYAMKVMKKEVLA-------ARENFHRAQTEK-EILKALDHPFLPRLLAHFETDKHT
|...| || |  | |..|   .|                     ||||| .|.          ...     ..|.  ||| . |||.  |   | |..  
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

FLVTDYCCGGDLNVLRQKQPDKRFSESATRFYAAEVLLALEYLHEHGIIYRDLKPENILIKENGHVMLTDFDLSL-NLATKKKTSS
..| ||  ||..    |.   |.|.|.  ||||||. .||||||.  ||||||||||||    ||. |||| |.  . .|...|..
YFVMDYVNGGEMFYHLQRE--KHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFT
Kinase RSK-p3_e-1.AA PKA 47-191 41 2.5e-49 170.18 In-house 1-145 (263) Show / Hide 
Range on Protein: 47-191
Range on HMM: 1-145/263
Sequence Identity: 41% (61 aa)

FRIIKSIGHGDMGTVFLVALRGDNSPYAMKVMKKEVLAARENFHRAQTEKEILKALDHPFLPR-LLAHFETDKHTFLVTDYCCGGDLNVLRQKQPDKRFS
| ||...| |  |.| |.  ...   ||||..||.    .   ..  .|| ||....|||. . . ..| .|.. ..| .|..||..    .|   .|||
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKS--GRFS

ESATRFYAA-EVLLALEYLHEHGIIYRDLKPENILIKENGHVMLTDF
.. ..|||| .. ||||||| . ||||||||||||| .|||. .|||
NPHAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDF
Kinase RSK-p3_e-1.AA PKC 47-191 43 1.7e-47 151.92 In-house 1-144 (262) Show / Hide 
Range on Protein: 47-191
Range on HMM: 1-144/262
Sequence Identity: 43% (63 aa)

FRIIKSIGHGDMGTVFLVALRGDNSPYAMKVMKKEVLAARENFHRAQTEKEILK-ALDHPFLPRLLAHFETDKHTFLVTDYCCGGDLNVLRQKQPDKRFS
|. .| .| |  | |.|. ..| .  ||.||.||.|    .    ..||| .|  |  ||||  |   | |  . | |  |. ||||    . |  .||.
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDL--MFHIQQQRRFK

ESATRFYAAEVLLALEYLHEHGIIYRDLKPENILIKENGHVMLTDF
|. .||||||...|| .|||.|||||||| .|.|. . ||. ..||
EEHARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADF
Kinase RSK-p3_e-1.AA Pkinase 47-194 35 1.6e-42 151.39 Pfam 1-159 (293) Show / Hide 
Range on Protein: 47-194
Range on HMM: 1-159/293
Sequence Identity: 35% (58 aa)

FRIIKSIGHGDMGTVFLVALRGDNSPYAMKVMKKEVLAARENFHRAQT---EKEILKALDHPFLPRLLAHFETDKHTFLVTDYCCGG----DLN----VL
..|.. || | .|.|..   .|..  .|.|..||.   ........ .   | .|.| |.||.  ||.  ||...|  .|..|| ||    ||     . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR--HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST-

RQKQPDKRF--SESATRFYAAEVLLALEYLHEHGIIYRDLKPENILIKENGHV----MLTDFDLS
   . ...|  ||   .||. ..| .|||.|..|||.||||||||||..|||.     ..|| |.
---WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLA
Kinase RSK-p3_e-1.AA RSK-Unclassified 267-368 42 4.8e-42 129.53 In-house 178-283 (283) Show / Hide 
Range on Protein: 267-368
Range on HMM: 178-283/283
Sequence Identity: 42% (45 aa)

RSNSFVGTEEYVAPEVVWGSGHGLPVDWWTFGVFLYELVYAKTPFKGSRRKDTFYNILCKEVELP---GPPTPLKDLIAGLLVKDPEQRLGSRQG-ALEV
| |||.|||||.|||.. . ||.  ||||| |. .||.    .|..|  .  |||||. ..| .|         .|||  || . |  |||. .| | ..
RTNSFCGTEEYLAPEMIRRCGHTKAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDI

RNHAFF
. | ||
KRHPFF
Kinase RSK-p3_e-1.AA MAST 47-194 41 3.7e-40 126.93 In-house 1-146 (334) Show / Hide 
Range on Protein: 47-194
Range on HMM: 1-146/334
Sequence Identity: 41% (61 aa)

FRIIKSIGHGDMGTVFLVALRGDNSPYAMKVMKKEVLAARENFHRAQTEKEILKALDHPFLPRLLAHFETDKHTFLVTDYCCGGDLNVLRQKQPDKRFSE
| .|| |. |  | |.||  .  |  .||||.||  .. .   .  |.|. ||. .. ||   .   |.|... ..| .|  |||.. | .     .| |
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYG--YFDE

SATRFYAAEVLLALEYLHEHGIIYRDLKPENILIKENGHVMLTDFDLS
. ...| ||. |.|||||.|||. |||||.|.||  |||. |||| ||
WMAKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLS
Kinase RSK-p3_e-1.AA SGK 270-368 44 8.7e-32 95.08 In-house 184-283 (283) Show / Hide 
Range on Protein: 270-368
Range on HMM: 184-283/283
Sequence Identity: 44% (45 aa)

SFVGTEEYVAPEVVWGSGHGLPVDWWTFGVFLYELVYAKTPFKGSRRKDTFY-NILCKEVELPGPPTPL-KDLIAGLLVKDPEQRLGSRQGALEVRNHAF
.| || || ||||  . .|.  ||||  | .|||. | . ||  || | . | ||. ..  .|   ..  .||| ||| |||..|||......|..|| |
TFCGTPEYLAPEVLRKQPHDRTVDWWCLGCVLYEMMYGLPPFY-SRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPF

F
|
F
Kinase RSK-p3_e-1.AA MAST 272-368 40 7.8e-31 96.37 In-house 225-334 (334) Show / Hide 
Range on Protein: 272-368
Range on HMM: 225-334/334
Sequence Identity: 40% (45 aa)

VGTEEYVAPEVVWGSG-HGLPVDWWTFGVFLYELVYAKTPFKGSRRKDTFYNILCKE---VELP-G--------PPTPLKDLIAGLLVKDPEQRLGSRQG
.|| .| ||||  | | || |||||  |. .||.    .|| .. .  .| ||| ..   .|.| |        .. . .|||  ||  ||..|||.. |
CGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGANNG

ALEVRNHAFF
| || .| ||
ADEVKQHPFF
Kinase RSK-p3_e-1.AA Akt 269-368 39 7.4e-30 92.56 In-house 160-264 (264) Show / Hide 
Range on Protein: 269-368
Range on HMM: 160-264/264
Sequence Identity: 39% (41 aa)

NSFVGTEEYVAPEVVWGSGHGLPVDWWT-FGVFLYELVYAKTPFKGSRRKDTFYNILCKEVELPGP---PTPLKDLIAGLLVKDPEQRLG-SRQGALEVR
..| || || |||.  | ||. .||||. .|...||. .   ||    ..  | .|. ..|. |         |||| ||| |||..|||   ..| |..
KTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIK

NHAFF
.| .|
RHPWF
Kinase RSK-p3_e-1.AA Pkinase 269-368 25 1.1e-26 95.49 Pfam 169-293 (293) Show / Hide 
Range on Protein: 269-368
Range on HMM: 169-293/293
Sequence Identity: 25% (33 aa)

NSFVGTEEYVAPEVVW-GSGHGLPVDWWTFGVFLYELVYAKTPFKGS------RRKDTFYNILCKEVELPGP----------------------PTPLKD
..|.|| .|.||||.  |...| .||.| .|. |||..  ..||.|.      . .  ...|...... . |                      . ..||
TTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKD

LIAGLLVKDPEQRLGSRQGALEVRNHAFF
.| ..| |||..|..    | .. .| .|
FIKWCLCKDPKKRPT----AEQILQHPWF
Kinase RSK-p3_e-1.AA PKC 267-368 32 3.1e-23 72.03 In-house 156-262 (262) Show / Hide 
Range on Protein: 267-368
Range on HMM: 156-262/262
Sequence Identity: 32% (35 aa)

RSNSFVGTEEYVAPEVVWGSGHGLPVDWWTFGVFLYELVYAKTPFKGSRRKDTFYNILCKEVELPGP-PTPLKDLIAGLLVKDPEQRLGS----RQGALE
. ..| || .|.|||.. .   |  |||| ||| .||.   . || |    . | .|. ...  |       .... |.. |.||.|||.    ..|. .
TTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPFHGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQD

VRNHAFF
.| |.||
IREHPFF
Kinase RSK-p3_e-1.AA PKA 273-368 32 5.9e-22 79.26 In-house 160-263 (263) Show / Hide 
Range on Protein: 273-368
Range on HMM: 160-263/263
Sequence Identity: 32% (34 aa)

GTEEYVAPEVVWGS-GHGLPVDWWTFGVFLYELVYAKTPFKGS--RRKDTFYNILCKEVELPGPPTP-L---KDLIAGLLVKDPEQRLGSRQ-GALEVRN
|| || |||.. .. ||| .||||..|.  ||..  ..||  .     ...  |.  ... |   .. .   ||||  ||..|...|.|. . |.  ..|
GTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKN

HAFF
| .|
HKWF
Kinase RSK-p3_e-1.AA TyrKc 47-362 13 1.2e-09 -66.96 SMART 1-280 (280) Show / Hide 
Range on Protein: 47-362
Range on HMM: 1-280/280
Sequence Identity: 13% (52 aa)

FRIIKSIGHGDMGTVFLVALRGDNSPYAMKVMKKEVLAARENFHRAQTEKEILKAL--DHPFLPRLLAHFETD-------KHTFLVTDYCCGGDLNVLRQ
 . .| .|.|  |.|..  ..    . | |..|..    || |.|   | .|.. |  .|| . ||..   ..       .  ..|. |...|||.   .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMR---EARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KQPDKRFSESATRFYAAEVLLALEYLHEHGIIYRDLKPENILIKENGHVMLTDFDLSLNLATK-------KKTSSSS--SSP------------------
|  .| .. .    ..  .    ||||....| |||   |.|..||..|  .|| || ..  .       .  ....  ..                   
KHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

---------------LFTDKKKKPSK-----------------PRRLSCGLHFELPRIITQRRKNTSKSCKKAVARIFPRSCGSSSDCRSNSFVGTEEYV
               .||. .. ..                   .|. .  . . | .                                          
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MS-----------------------------------------

APEVVWGSGHGLPVDWWTFGVFLYELVYAKTPFKGSRRKDTFYNILCKEVELPGPPTPLKDLIAGLLVKDPEQRLGSRQGALEV
                                                    .. |. . ...      |||.|   ..   . 
---------------------------------------------------FVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase RSK-p3_e-1.AA Pkinase_Tyr 47-191 26 2e-06 22.43 Pfam 1-155 (270) Show / Hide 
Range on Protein: 47-191
Range on HMM: 1-155/270
Sequence Identity: 26% (42 aa)

FRIIKSIGHGDMGTVFLVALR----GDNSPYAMKVMKKEVLAA---RENFHRAQTEKEILKAL-DHPFLPRLLAHFE-TDKH--TFLVTDYCCGGDL-NV
 ...| .|.|  |.|..  ..    ... | | |..|         || | |   | .|.| | .|| . ||..     ...   ..|. |...||| . 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR---EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

LRQK-QPDKRFSESATRFYAAEVLLALEYLHEHGIIYRDLKPENILIKENGHVMLTDF
||..  ...... .    .....  ..|||.....| |||   |.|..||..|  .||
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDF
Kinase RSK-p3_e-1.AA Pkinase_Tyr 295-313 33 5.090112 0.69 Pfam 198-218 (270) Show / Hide 
Range on Protein: 295-313
Range on HMM: 198-218/270
Sequence Identity: 33% (7 aa)

WTFGVFLYELVY-AKTP-FKG
| ||| ..|..   ..| ..|
WSFGVLMWEIFTYGEQPTYPG