Gene CAMK1c-S5_ab (S.moellendorffii)

CAMK1c-S5_ab

Species: S.moellendorffii
Alias: CAMK1c-S5_ab
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK1
Subfamily: CAMK1c

Sequence

Name Sequence Type Origin Length Description Download
CAMK1c-S5_ab.AA Protein None 237 None Fasta, JSON
CAMK1c-S5_ab.NA RNA None 714 None Fasta, JSON
CAMK1c-S5_ab.kin_dom Protein Kinase Domain None 174 None Fasta, JSON

Protein domain

Protein domains of CAMK1c-S5_ab.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CAMK1c-S5_ab.AA AGC 45-200 23 5.9e-48 120.94 In-house 140-393 (395) Show / Hide 
Range on Protein: 45-200
Range on HMM: 140-393/395
Sequence Identity: 23% (63 aa)

SGRMSEEEAAQIVKQ-------LAETLKEMHS-RGIIHRD-LKPGNILFKLDARDKVVISDFGIATDDP-------------------------------
.||..||.|  .  .       ..  |  .|| .|||||| ||| |||  ||..  . ..||| ..  .                               
EGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENIL--LDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNK

----------------------EEMLQYCG--TAKYMAPEVAENKDGSFYTAAIDVWG--LGAILYEMLGKGGYQP----S------------EAFDCVR
                      .     ||  |. |||||.        |. | | |.  ||...||||   || |    .            | |. ..
CNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-------YGKACDWWSFGLGCLMYEML--TGYPPFYGDNPQENRHPFRNPMEMFQKIM

QG-----ASPVGP------------FSFVAEDLLDKMLAVDPKQRLT----------VDQVLQHP
 |       .  |            ||  | ||. |.| .||..||.          .... .||
NGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHP
Kinase CAMK1c-S5_ab.AA Ciliate-E2a 29-144 40 1.4e-40 117.14 In-house 76-207 (275) Show / Hide 
Range on Protein: 29-144
Range on HMM: 76-207/275
Sequence Identity: 40% (54 aa)

IIMELC-GSSLADCLRVSGRMSEE--EAAQIVKQLA-ETLKEMHSRGIIHRDLKPGNILFK-LDAR----DKVVISDFGIATDD--PEE--MLQYCGTAK
..||.| | .| | .. ..|. ||  |...| .||  . |  ||.|.|.|||||| ||||| ...      ...|.||| ||.    |.  | | |||. 
LVMEYCEGGELYDKIKQCKRFFEEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPG

YMAPEVAENKD---GSFYTAAIDVWGLGAILY
|.||||. ||.   . .|.   |.| .|.|.|
YVAPEVLNNKEVLKHKQYDTKCDMWSCGVIFY
Kinase CAMK1c-S5_ab.AA CAMK 29-147 25 4.5e-39 123.07 In-house 134-328 (425) Show / Hide 
Range on Protein: 29-147
Range on HMM: 134-328/425
Sequence Identity: 25% (49 aa)

IIM---ELCGS-----SLADCLRVS---------------GRMSEEEAAQIVKQLAETLKEMHSRGIIHRDLKPGNILFKLDARD---------------
..|   |.|        | | ..                 ||..|.||.....|... .. .||..|.|||||| |||.  . .|               
MVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNN

KVVISDFGIATDDPE--------------------------EMLQYCGTAKYMA-PEVAENKD-----------GSFYTAAIDVWGLGAILYEML
.. |.||| |.  ..                           |  .|||  ||| ||| . |               |. ..|.| .| ||| ||
NIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIML
Kinase CAMK1c-S5_ab.AA RSK 29-200 31 1.6e-38 134.3 In-house 78-276 (278) Show / Hide 
Range on Protein: 29-200
Range on HMM: 78-276/278
Sequence Identity: 31% (63 aa)

IIMELC-GSSLADCLRVSGR---MSEEEAAQIVKQLAETLKEMHSRGIIHRDLKPGNILFKLDA-RDKVVISDFGIATD-DPE--EMLQ-YCGTAKYMAP
.|||.| |  | . |.  ..   .||.||...  ... ... .|..||||||||| |||.  .  .  ....||| .   ...  .... .|.|. ||||
LIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAP

EVAE--NKDGSFYTAAIDVWGLGAILYEML-------GKGGY-QPSEAFDCVRQGA-SPVGP----FSFVAEDLLDKMLAVDPKQRLT-----VDQVLQH
|.    |  .. ...| |.| ||...||||       | ..  ...| .. ...|  |. .|     |  | ||. ||| .||..||.     .....||
EMLKRAN-QQGGHDKACDWWSLGVLMYEMLTGCPPFQG-PNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQH

P
|
P
Pkinase CAMK1c-S5_ab.AA Pkinase 1-147 35 1.6e-37 133.73 Pfam 54-206 (293) Show / Hide 
Range on Protein: 1-147
Range on HMM: 54-206/293
Sequence Identity: 35% (58 aa)

MAKLRGCPGVVSFRDFIKERDGGQCFGSIIMELC-GS----SLADCLR--VSGRM--SEEEAAQIVKQLAETLKEMHSRGIIHRDLKPGNILFK--LDAR
|..| ..| .| ..|.  .  .. .   ..||.| |     .|.| ..   .|..  ||.|.  ...|... |. .||.||||||||| |||..   .  
MKRL-NHPNIVRLYDWFED--KDHIY--MVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHID

DKVVISDFGIA----TDDPEEMLQYCGTAKYMAPEVAENKDGSFYTAAIDVWGLGAILYEML
..| |.|||.|    .   . |  .|||  ||||||   ..|. |. ..|.|..| ||||||
ACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEV--IRGGQYYGPKVDMWSCGCILYEML
Kinase CAMK1c-S5_ab.AA CAMKL 29-202 30 1.9e-37 116.94 In-house 98-297 (297) Show / Hide 
Range on Protein: 29-202
Range on HMM: 98-297/297
Sequence Identity: 30% (63 aa)

IIMELCGSS---LADCLRVS----GRMSEEEAAQIVKQLAETLKEMHSRGIIHRDLKPGNILFKLDARD--KVVISDFGIATD-DP-----EEMLQ-YCG
..||.|..    | | ..      |||.|.|| .. .|. . .. .||.||.|||.|| |||  || ..  .. |.||| ..  .|     ...|   ||
LVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENIL--LDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCG

TAKYMAPEVAENKDGSFYTAAIDVWGLGAILYEMLGKGGYQP-SEA------------FDCVRQGASPVGPFSFV--AEDLLDKMLAVDPKQRLTVDQVL
.  |||||. .    ...  ..|.| .| ||| |.   || |  ..            .  ...|     ....|  ..||. ||| |.|..| |..|..
SPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMV--CGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIM

QHPCR
.||  
NHPWM
Kinase CAMK1c-S5_ab.AA Ciliate-E2 29-147 26 5e-37 124.64 In-house 111-290 (365) Show / Hide 
Range on Protein: 29-147
Range on HMM: 111-290/365
Sequence Identity: 26% (50 aa)

IIMELCGS-SLADCLRVS-----------GRMSEEEAAQIVKQLAE---------------TLKEMHSRG-IIHRDLKPGNILFKLDARDKVVISDFGIA
..||.|   .| |... .           ....|.|...| ||...                |...||.. |||||.|| ||||       . |.|||..
LVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-------IKIIDFGLS

T---DDPEEMLQ-------------------------------YCGTAKYMAPEVAENKD------GSFYTAAIDVWGLGAILYEML
.   || .. ..                               .|||. |||||. ..|.      .  |. ..|.| || ||||||
KKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEML
Kinase CAMK1c-S5_ab.AA MSK 29-147 38 2.7e-33 109.92 In-house 78-204 (277) Show / Hide 
Range on Protein: 29-147
Range on HMM: 78-204/277
Sequence Identity: 38% (49 aa)

IIMELC-GSSLADCLRVSGRMSEEEAAQIVKQLAETLKEMHSRGIIHRDLKPGNILFKLDAR-DKVVISDFGIATDDPEEMLQ----YCGTAKYMAPEVA
..||.| |  |   .| .....|.|...|. .|   .. ||..||||||||| ||||  .    .|...||| |   |... .    .|.|  |||||. 
LVMEYCNGGELFTHIRKREHFDESECRMIMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDNGHVKLIDFGFARLFPQDEEWRMKSPCFTLHYMAPEML

EN-KDGSF-YTAAIDVWGLGAILYEML
.    .   | .|.|.|.||.|||.||
RRGYAQDGGYDEACDWWSLGVILYTML
Kinase CAMK1c-S5_ab.AA CAMK1 49-144 43 1e-32 92.35 In-house 106-207 (276) Show / Hide 
Range on Protein: 49-144
Range on HMM: 106-207/276
Sequence Identity: 43% (44 aa)

SEEEAAQIVKQLAETLKEMHSRGIIHRDLKPGNILFKLDARD-KVV--ISDFGIA--TDDPE-EMLQYCGTAKYMAPEVAENKDGSFYTAAIDVWGLGAI
.|..|. |.||... .. |||.|| |||||| |.|..    | |..  |.|||..  .|. |  | . |||  |.|||| |.|   .|  |.|.|. | |
TEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMWSIGVI

LY
.|
TY
S_TKc CAMK1c-S5_ab.AA S_TKc 1-202 27 4.1e-32 113.93 SMART 17-231 (231) Show / Hide 
Range on Protein: 1-202
Range on HMM: 17-231/231
Sequence Identity: 27% (67 aa)

MAKLRG------------------------CPGVVSFRDFIKERDGGQCFGSIIMELCGS---SLADCLRVSGR------MSEEEAAQIVKQLAETLKEM
 .. ..                        .| .| . |.. .      .  ..||.|.    .| | ..  ||      ..| .|. ...|... |. .
KCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYC

HSRGIIHRDLKPGNILFKLDARDKVVISDFGIATDDPEEMLQYCGTAKYMAPEVAENKDGSFYTA-AIDVWGLGAILYEMLG-----KGGYQPSEAFDCV
||.||||||||| |||.       . |.|||.|.        .|||  ||||||        |.  ..|.| .| ||||||          |. . |. .
HSHGIIHRDLKPENILLDE----HIKICDFGLARQL----TTFCGTPWYMAPEVL------GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKI

RQGASPVGPFSFVAEDLLDKMLAVDPKQRLTVDQVLQ-------HPCR
.         |  | |...|.| .||..|.|. ..||       ||  
G---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CAMK1c-S5_ab.AA Ciliate-E2-Unclassified 29-147 27 1.3e-31 106.91 In-house 98-264 (352) Show / Hide 
Range on Protein: 29-147
Range on HMM: 98-264/352
Sequence Identity: 27% (47 aa)

IIMELC-GSSLADCLRVS-----------------GRMSEEEAA-----QIVKQLAETLKEMHSRG-IIHRDLKPGNILFKLDAR-DKVVISDFGIAT--
|.||.| | .| .... .                  . .|..|.     .. .|. . |. .|. . |||||.|| ||||. . .  .. |.||||.   
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKY

-DD---------------PEEMLQYCGTAKYM----APEVAEN-KDG--SFYTAAIDVWGLGAILYEML
 ..               ...| . |||  ||    |||| .. . .  ..   ..|.|.|| ||||||
QQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA--YKCDIWSLGVILYEML
Kinase CAMK1c-S5_ab.AA ULK 29-147 31 9.2e-27 90.51 In-house 97-250 (329) Show / Hide 
Range on Protein: 29-147
Range on HMM: 97-250/329
Sequence Identity: 31% (49 aa)

IIMELCGS-SLADCLRVSGR----------MSEEEAAQIVKQLAETLKEMHSRGIIHRDLKPGNILFKLDARDK----------VVISDFGIATD-DPE-
||||.|    | . .   ..           ||.|| |. ||... .||.|...|||||.|| ||| . .   .          . |.||| |   | . 
IIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDN

----EMLQYC------GTAKYMAPEVAENK--DGSFYTAAIDVWGLGAILYEML
     |. .       ||  ||||.. ...     .|..  |.| || |.||||
MEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEML
Kinase CAMK1c-S5_ab.AA CAMK 169-202 25 2.2e-10 28.93 In-house 362-425 (425) Show / Hide 
Range on Protein: 169-202
Range on HMM: 362-425/425
Sequence Identity: 25% (16 aa)

GPFSFV------------------------------AEDLLDKMLAVDPKQRLTVDQVLQHPCR
| ..|                               . ||. ||| |||..|.|..|.|.||  
GKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase CAMK1c-S5_ab.AA CAMK1 177-200 54 6.6e-10 24.91 In-house 251-274 (276) Show / Hide 
Range on Protein: 177-200
Range on HMM: 251-274/276
Sequence Identity: 54% (13 aa)

DLLDKMLAVDPKQRLTVDQVLQHP
|.. .|| ||||.|.|..|.|.||
DFIKHMLEVDPKKRYTCEQCLNHP
Kinase CAMK1c-S5_ab.AA Ciliate-E2 175-202 39 6.4e-08 23.26 In-house 333-365 (365) Show / Hide 
Range on Protein: 175-202
Range on HMM: 333-365/365
Sequence Identity: 39% (13 aa)

AEDLLDK----MLAVDPKQRLT-VDQVLQHPCR
. ||. |    || .||..|.|  .|.|.||  
CKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase CAMK1c-S5_ab.AA Ciliate-E2a 177-200 58 8.8e-08 19.01 In-house 250-273 (275) Show / Hide 
Range on Protein: 177-200
Range on HMM: 250-273/275
Sequence Identity: 58% (14 aa)

DLLDKMLAVDPKQRLTVDQVLQHP
||. ||| .|||.|.|  | |.||
DLMKKMLEKDPKKRITAQQALNHP
Kinase CAMK1c-S5_ab.AA ULK 170-202 30 1.4e-07 22.66 In-house 297-329 (329) Show / Hide 
Range on Protein: 170-202
Range on HMM: 297-329/329
Sequence Identity: 30% (10 aa)

PFSFVAEDLLDKMLAVDPKQRLTVDQVLQHPCR
..|   .||. .|| .|.|.| . .....||. 
QISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase CAMK1c-S5_ab.AA Ciliate-E2-Unclassified 172-200 39 3.4e-07 21.03 In-house 318-350 (352) Show / Hide 
Range on Protein: 172-200
Range on HMM: 318-350/352
Sequence Identity: 39% (13 aa)

SFVAEDLLD----KMLAVDPKQRLTVDQVLQHP
|. |.|..     ||| ..|..|.| .|.|.||
SPEAKDFINDLLQKMLKKNPNKRITFEQILNHP
TyrKc CAMK1c-S5_ab.AA TyrKc 1-200 18 7.4e-07 -111.74 SMART 1-280 (280) Show / Hide 
Range on Protein: 1-200
Range on HMM: 1-280/280
Sequence Identity: 18% (55 aa)

MA-------------------------KLRGCPGVVSFRDFIKERD-----G----------GQCFGS-----------IIMELCGS-SLADCLRVSGR-
                           .|. .      .||..|       |          | |  .           |.||..   .| | || ... 
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

MSEEEAAQIVKQLAETLKEMHSRGIIHRDLKPGNILFKLDARDKVVISDFGIATDDPEE------MLQY------CGT----AKYMAPEVAENKDGSFYT
 . ..  ..  | |.     ||...|||||   |.|  ....  | ||||| . |  ..         |      .|      . ||||.   ..| | |
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCL--VGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NYGKFTT

AAIDVWGLGAILYEMLGKGGYQPSE----------AFDCVRQG---ASPVG--------PFSFVAEDLLDKMLAVDPKQRLTVDQVLQHP
.  |||  |  ..|..  |.  ...          .. .|.||     |            . . . .  .  . ||..| |  .. .  
KS-DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF
Kinase CAMK1c-S5_ab.AA Pkinase 175-200 46 2e-06 23.7 Pfam 266-291 (293) Show / Hide 
Range on Protein: 175-200
Range on HMM: 266-291/293
Sequence Identity: 46% (12 aa)

AEDLLDKMLAVDPKQRLTVDQVLQHP
. |.....|..|||.|.| .|.||||
CKDFIKWCLCKDPKKRPTAEQILQHP
Kinase CAMK1c-S5_ab.AA MSK 171-202 34 5e-06 16.41 In-house 246-277 (277) Show / Hide 
Range on Protein: 171-202
Range on HMM: 246-277/277
Sequence Identity: 34% (11 aa)

FSFVAEDLLDKMLAVDPKQRLTVDQVLQHPCR
.| .| ||. ..| .||| ||...  ..|  .
MSPDAKDLIQWLLTKDPKKRLGMNDLRAHEWK