Gene CAMK1c-S4_g (S.moellendorffii)

CAMK1c-S4_g

Species: S.moellendorffii
Alias: CAMK1c-S4_g
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK1
Subfamily: CAMK1c

Sequence

Name Sequence Type Origin Length Description Download
CAMK1c-S4_g.AA Protein None 340 None Fasta, JSON
CAMK1c-S4_g.NA RNA None 1023 None Fasta, JSON
CAMK1c-S4_g.kin_dom Protein Kinase Domain None 247 None Fasta, JSON

Protein domain

Protein domains of CAMK1c-S4_g.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc CAMK1c-S4_g.AA S_TKc 20-266 28 5.6e-47 163.3 SMART 1-231 (231) Show / Hide 
Range on Protein: 20-266
Range on HMM: 1-231/231
Sequence Identity: 28% (76 aa)

YIRHEKLGHGGQGQVYLLSDAARNRHRYAGKMFKLESCAERETRILDKLRPIPGVVFLHGLRRERKVGGRCFGTMVMELCGP---SLRDLAMKGP-----
|  ..|.|.|. |.||.  .     ...| |. |    ..|| .|| |    | .| |..  ..       .  ||||.|.    .|.|.  | .     
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK--EHIRREIQILKK--HHPNIVKLYDVFQD------DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LREEEVAEIVKELAETLKGVHSSGVVHRDLKLENVFTKLQDESTIRPVIGDFGVATDDAREMSQSCGTEKYMAPELIFVERYGLSYTK-AVDV---GV
  . | ... ....... |.  || |..||||| ||..         .  |.|||.|.      .  |||  |||||..       .|.| ..|.   |.
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL----TTFCGTPWYMAPEVL-------GYGKCKCDWWSCGC

IAYELLKGYQ---RSNLEMHLLREGEFQWPANLSPEAKNLIMGMLDLDPRKRLTLDQVIN-------HPWI
| ||.| ||      .. .....          |||||..|...|. ||.||.|  .. .       |||.
ILYEMLCGYPPFPQMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase CAMK1c-S4_g.AA Pkinase 20-266 26 5.1e-39 139.06 Pfam 1-293 (293) Show / Hide 
Range on Protein: 20-266
Range on HMM: 1-293/293
Sequence Identity: 26% (81 aa)

YIRHEKLGHGGQGQVYLLSDAARNRHRYAGKMFKLESCAE---------RETRILDKLRPIPGVVFLHGLRRERKVGGRCFGTMVMELCGP-----SLRD
| ...|.| |. |.||.  .   .. ..| | .|...  .         .| .|. .|.  | .| |..  ..   ....   ||||.|.      .| |
YHIGRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN-HPNIVRLYDWFED---KDHIY--MVMEYCEGGLYVMDLFD

LAM---KGPL--REEEVAEIVKELAETLKGVHSSGVVHRDLKLENVFTKLQDEST---IRPVIGDFGVA----TDDAREMSQSCGTEKYMAPELIFVERY
. .   .|..   |.|.  ....... |.  || |..|||||.||.. . ..  .   ..  |.|||.|    .   . |.  |||  |||||.|     
YISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVK--ICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR---G

GLSYTKAVDV---GVIAYELLKG----YQR------SNLEMHLLREG---EFQWPANLS-------------------PEAKNLIMGMLDLDPRKRLTLD
|  |...||.   |.| ||.| |    ...      . ..|. .. |   .|.||   |                   .|.| .| ..|..|| ||.| .
GQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAE

QVINHPWI
|. .|||.
QILQHPWF
Kinase CAMK1c-S4_g.AA CAMK 25-266 18 2.2e-37 117.49 In-house 1-425 (425) Show / Hide 
Range on Protein: 25-266
Range on HMM: 1-425/425
Sequence Identity: 18% (78 aa)

KLGHGGQGQVYLLSDAARNR-----------HRYAGKMFK---------------------------------LESCAERETRILDKLRP------IPGV
.||.|. |.|.|  .   ..           ...| |. .                                  .   .|| .|. ||.        | .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VFLHGLRRERK---------VGGR-CFGT------MVM---ELCGPS------LRDLAMKGP---------------LREEEVAEIVKELAETLKGVHSS
. |.     ..            .  | |      |||   |.|         .  .  .|.               . |.|.. ... ... ..  || 
IKLYEVYEDPHYFKNTNDYET-SKQVF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSH

GVVHRDLKLENVFTKLQDESTI-------------RPVIGDFGVATDDAR--------------------------EMSQSCGTEKYMA-PELIFVERYG
..||||||.||.     ....                 | ||| |.   .                           |. .|||  ||| ||..  .. .
NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

LS----------YTKAVDV---GVIAYELLKG----YQR-------------SNLEMH-LLREGEFQWPAN------------------------LSPEA
 .          |....|.   ||| | .| |    |               .  |..   ..|....|                          .|.|.
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQEC

KNLIMGMLDLDPRKRLTLDQVINHPWI
|.|| .||  || ||.|..|. ||||.
KDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase CAMK1c-S4_g.AA Ciliate-E2 94-266 22 2.4e-30 101.36 In-house 111-365 (365) Show / Hide 
Range on Protein: 94-266
Range on HMM: 111-365/365
Sequence Identity: 22% (61 aa)

MVMELC-GPSLRD--------------LAMKGPLREEEVAEIVKELAE---------------TLKGVHSSG-VVHRDLKLENVFTKLQDESTIRPVIGD
.|||.| | .|.|                  ... |.|...| |....                |.  || . ..|||.|.||..          . | |
LVMEYCQGGDLFDYIKNNKKKRNHEIEK-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---------IKIID

FGVATDDARE------MSQS----------------------------CGTEKYMAPELIFVERY-----GLSYTKAVD---VGVIAYELLKG---YQRS
|| ...   .      ..|.                            |||  ||||| .  . |     .  |....|   .||| ||.| |   .   
FGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF---

NLEMHLLREGEFQWP------------------ANLSPEAKNLIMG----MLDLDPRKRLT-LDQVINHPWI
   .    ..... |                   ..|.|.|.||      ||. || ||.|  .|..||||.
---QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase CAMK1c-S4_g.AA Ciliate-E2-Unclassified 94-266 22 7.5e-30 100.74 In-house 98-352 (352) Show / Hide 
Range on Protein: 94-266
Range on HMM: 98-352/352
Sequence Identity: 22% (58 aa)

MVMELC-GPSLRDLAMK------------------GPLREEEVA-----EIVKELAETLKGVHSSG-VVHRDLKLENVFTKLQDESTIRPVIGDFGVAT-
.|||.| | .|..   |                    . |....      . ... . |.  |... ..|||.|.||.. . . .   .. | ||| .  
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK-NYYIKIIDFGISKK

--DD---------------AREMSQSCGTEKYM----APELIFVERYGLSYTKAVD---VGVIAYELLKGY----QRSNLE----------------MHL
  ..                 .|.. |||  ||    |||..  . |. |  ...|   .|||.||.| ||    ...  .                .. 
YQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQ

LR-EGEFQ----WP----ANLSPEAKNLIM----GMLDLDPRKRLTLDQVINHPWI
   ....|    ..     ..|||||..|      ||. .| ||.|..|..||||.
NIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase CAMK1c-S4_g.AA MSK 109-266 31 2.9e-29 96.06 In-house 95-277 (277) Show / Hide 
Range on Protein: 109-266
Range on HMM: 95-277/277
Sequence Identity: 31% (58 aa)

KGPLREEEVAEIVKELAETLKGVHSSGVVHRDLKLENV-FTKLQDESTIRPVIGDFGVATDDAREMSQ---S-CGTEKYMAPELIFVERYGLS-YTKAVD
..  .|.|...|. ||   ..  |. |..|||||.||. |.  .|. ..  .. ||| |    .....   | |.|  |||||.. .   . . | .|.|
REHFDESECRMIMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDNGHV--KLIDFGFARLFPQDEEWRMKSPCFTLHYMAPEMLRRGYAQDGGYDEACD

V---GVIAYELLKG---YQ--RSNLE---------MHLLREGEFQWP----ANLSPEAKNLIMGMLDLDPRKRLTLDQVINHPWI
.   ||| |..| |   .|   .  .         |   ..|||  |     | ||.||.|| ..|  || |||...    | |.
WWSLGVILYTMLTGQVPFQQNEDDRQHSCNSHHEIMKRICKGEFSFPGMAWQNMSPDAKDLIQWLLTKDPKKRLGMNDLRAHEWK
Kinase CAMK1c-S4_g.AA AGC 160-266 18 8.6e-29 70.23 In-house 196-395 (395) Show / Hide 
Range on Protein: 160-266
Range on HMM: 196-395/395
Sequence Identity: 18% (38 aa)

IGDFGVATDDARE-----------------------------------------------------MSQSCG--TEKYMAPELIFVERYGLSYTKAVD--
. ||| ..   ..                                                      .  ||  |  ||||| .        |.||.|  
LTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL--------YGKACDWW

---VGVIAYELLKG----------------YQRSNLEMHLLR-----EGEFQWP----------ANLSPEAKNLIMGMLDLDPRKRLT----------LD
   .|.. ||.| |                ...  .    .      . . ..|           ..|||||.|| ..|  ||.|||.           .
SFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAE

QVINHPWI
.. |||| 
EIKNHPWF
Kinase CAMK1c-S4_g.AA RSK 110-266 30 3.4e-26 92.93 In-house 99-278 (278) Show / Hide 
Range on Protein: 110-266
Range on HMM: 99-278/278
Sequence Identity: 30% (57 aa)

GPLREEEVAEIVKELAETLKGVHSSGVVHRDLKLENVFTKLQD---ESTIRPVIGDFGVATD-DAR--EMSQS-CGTEKYMAPELIFVERYGLS-YTKAV
| . |.|....  |.. ...  |. |..|||||.||.   . |   | .|  .. ||| .   ...  .. .. |.|  |||||.. .   . . ..||.
GCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENIL--YDDESNEGHI--KLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRAN-QQGGHDKAC

DV---GVIAYELLKG---YQR---SNLE--MHLLREGE--FQWP--ANLSPEAKNLIMGMLDLDPRKRLT-----LDQVINHPWI
|.   ||. ||.| |   .|    .| .  |   ..|.  .  |  ..||.|||.|| .||  || |||.     .... .|||.
DWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase CAMK1c-S4_g.AA ULK 109-266 23 6.1e-23 76.99 In-house 114-329 (329) Show / Hide 
Range on Protein: 109-266
Range on HMM: 114-329/329
Sequence Identity: 23% (50 aa)

KGP----------LREEEVAEIVKELAETLKGVHSSGVVHRDLKLENVFTKLQDEST--------IRPVIGDFGVATD-DAR------EMSQS-----CG
...          | |.|. .. | ... .|  |. ...|||.|..|.  .  ...|        ..  |.||| |   |        .|...     ||
NKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCG

TEKYMAPELIFVERYGLSYT-KAVDV---GVIAYELLKGY------QRSNLEMHLLRE-------------GEFQWP-----ANLSPEAKNLIMGMLDLD
|  ||||...  .  .  |. . .|.   |.| ||.| |.       ..  .... ..               .|.|      ..||| |.|| .||  |
TPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYD

PRKRLTLDQVINHPWI
...| . ....||||.
EKDRISWEELFNHPWF
Kinase CAMK1c-S4_g.AA CAMK-Unique 94-214 25 1.2e-17 54.66 In-house 112-290 (363) Show / Hide 
Range on Protein: 94-214
Range on HMM: 112-290/363
Sequence Identity: 25% (45 aa)

MVMELCGPS-LRDLAMK---------------------GPLRE--EEVAEIVKELAETLKGVHSSGVVHRDLKLENVFTKLQ------------DESTIR
.|||.|    | |. .|                     |.. |   ... |. .|.. ..  || ..|||||||||.  .              |.|  .
IVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHHRDFPYDWSNWH

PVIGDFGVATDDAREMSQS-----CGTEKYMAP--------------ELIFVERYGLSYTKAVDV---GVIAYELLKGY
 .. ||| ...     . .     |||. ||||              |.|   .|.     | |    |||.|..| |.
IKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGC
Kinase CAMK1c-S4_g.AA CAMK1 238-266 58 2.1e-16 44.13 In-house 248-276 (276) Show / Hide 
Range on Protein: 238-266
Range on HMM: 248-276/276
Sequence Identity: 58% (17 aa)

EAKNLIMGMLDLDPRKRLTLDQVINHPWI
|||..| .||..|| ||.| .|..|||||
EAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase CAMK1c-S4_g.AA CAMKL 94-188 27 3.9e-15 44.59 In-house 98-205 (297) Show / Hide 
Range on Protein: 94-188
Range on HMM: 98-205/297
Sequence Identity: 27% (30 aa)

MVMELCGPS---LRDLAMKGP-----LREEEVAEIVKELAETLKGVHSSGVVHRDLKLENVFTKLQDESTIRPVIGDFGVAT--DD-----AREMSQSCG
.|||.|.     | |   | .     . |.|   . . . . ..  || |.||||.|.||.    .. .     | ||| ..  ..      . .. .||
LVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN--NIKIIDFGFSNMYRPCIFGPGQKLKTFCG

TEKYMAPELI
.  |||||..
SPPYMAPEIF
Kinase CAMK1c-S4_g.AA CAMKL 219-266 32 2.5e-14 41.96 In-house 250-297 (297) Show / Hide 
Range on Protein: 219-266
Range on HMM: 250-297/297
Sequence Identity: 32% (16 aa)

LEMHLLREGEFQWPAN--LSPEAKNLIMGMLDLDPRKRLTLDQVINHPWI
....  ..| ...|    .| ....|| .||  .| || |..|. |||| 
YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase CAMK1c-S4_g.AA CAMK1 114-215 37 3.7e-14 37.48 In-house 107-214 (276) Show / Hide 
Range on Protein: 114-215
Range on HMM: 107-214/276
Sequence Identity: 37% (41 aa)

EEEVAEIVKELAETLKGVHSSGVVHRDLKLENV-FTKLQDESTIRPVIGDFGVA--TDDAR-EMSQSCGTEKYMAPELIFVERYGLSYTKAVD---VGVI
|.. ..|.|.... ..  || |.|||||| ||  .    ..|.|.. | ||| .  .|.    |.. |||  |.||| .        | ||.|   .|||
EKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKK-DKPYDKACDMWSIGVI

AYELLKGYQ
 | || ||.
TYILLCGYP
Kinase CAMK1c-S4_g.AA CAMK-Unique 236-266 32 1.5e-09 27.47 In-house 333-363 (363) Show / Hide 
Range on Protein: 236-266
Range on HMM: 333-363/363
Sequence Identity: 32% (10 aa)

SPEAKNLIMGMLDLDPRKRLTLDQVINHPWI
|.|||... . . .|| .|... . . |.||
SQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase CAMK1c-S4_g.AA TyrKc 20-266 21 6.2e-07 -110.5 SMART 1-280 (280) Show / Hide 
Range on Protein: 20-266
Range on HMM: 1-280/280
Sequence Identity: 21% (64 aa)

YIRHEKLGHGGQGQVYL--LSDAARNRHRYAGKMFKLESCAE--RETRILDKL-RPIPGVVFLHGLRRER-----KVGGRCFGTMVMELCGP-SLRDLAM
    .|||.|  |.||.  ..         | || | .. ..  || ||. ||    | .| |.|  ..       ..  .   .|||..   .|.|   
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLM---IVMEYMPHGDLKDYLR

KGP--LREEEVAEIVKELAETLKGVHSSGVVHRDLKLENVFTKLQDESTIRPVIGDFGVATDDARE-------MSQSC----GTE-----KYMAPELIFV
|    |  ..  ..    |.     || ...||||   |.  . .   |..  |.||| . |   .          .     |.      . |||| |  
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVK--ISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--

ERYGLSYTKAVDV---GVIAYELLKGYQRSNLE-----------MHLLREGEFQWPANL---------SPEAKNLIMGMLDLDPRKRLTLDQVINHPWI
 .||  .| . ||   ||  .|..   |    .           ......|.   .            ..|  ...    . || .| |  ..  |  .
-NYGK-FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase CAMK1c-S4_g.AA AGC 132-146 58 9.6e-07 11.91 In-house 170-186 (395) Show / Hide 
Range on Protein: 132-146
Range on HMM: 170-186/395
Sequence Identity: 58% (10 aa)

HS-SGVVHRD-LKLENV
||  |..||| ||.||.
HSHMGIIHRDYLKPENI
Kinase CAMK1c-S4_g.AA Ciliate-E2 20-39 35 0.000378 10.12 In-house 1-20 (365) Show / Hide 
Range on Protein: 20-39
Range on HMM: 1-20/365
Sequence Identity: 35% (7 aa)

YIRHEKLGHGGQGQVYLLSD
|. ..|.| |..|.||. ..
YKFIKKIGQGNFGSVYKCKV
Kinase CAMK1c-S4_g.AA Ciliate-E2-Unclassified 20-39 35 0.000562 9.71 In-house 1-20 (352) Show / Hide 
Range on Protein: 20-39
Range on HMM: 1-20/352
Sequence Identity: 35% (7 aa)

YIRHEKLGHGGQGQVYLLSD
|. ....|.||.|.||.. .
YKIIKQIGQGGFGKVYKCQH
Kinase CAMK1c-S4_g.AA ULK 20-35 43 0.003641 7.0 In-house 1-16 (329) Show / Hide 
Range on Protein: 20-35
Range on HMM: 1-16/329
Sequence Identity: 43% (7 aa)

YIRHEKLGHGGQGQVY
|. ...||.|  |.||
YCLNHCLGKGSFGKVY
Kinase CAMK1c-S4_g.AA CAMKL 20-36 41 0.101824 1.09 In-house 1-17 (297) Show / Hide 
Range on Protein: 20-36
Range on HMM: 1-17/297
Sequence Identity: 41% (7 aa)

YIRHEKLGHGGQGQVYL
|.  . ||.|. |.| |
YRIGKTLGKGSFGKVKL
Kinase CAMK1c-S4_g.AA RSK 23-36 50 0.33488 0.6 In-house 1-14 (278) Show / Hide 
Range on Protein: 23-36
Range on HMM: 1-14/278
Sequence Identity: 50% (7 aa)

HEKLGHGGQGQVYL
.. || ||.| |.|
LKVLGQGGYGKVFL