Gene CAMK1c-S1_d (S.moellendorffii)

CAMK1c-S1_d

Species: S.moellendorffii
Alias: CAMK1c-S1_d
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK1
Subfamily: CAMK1c

Sequence

Name Sequence Type Origin Length Description Download
CAMK1c-S1_d.AA Protein None 340 None Fasta, JSON
CAMK1c-S1_d.NA RNA None 1023 None Fasta, JSON
CAMK1c-S1_d.kin_dom Protein Kinase Domain None 206 None Fasta, JSON

Protein domain

Protein domains of CAMK1c-S1_d.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc CAMK1c-S1_d.AA S_TKc 1-267 26 1.2e-57 198.73 SMART 18-231 (231) Show / Hide 
Range on Protein: 1-267
Range on HMM: 18-231/231
Sequence Identity: 26% (75 aa)

MKRKVDGKFFACKTIRVSDYTIEDSITDDMLPDGGLREEAEAEIEALVHLSKMHSPSGGAMVPELVEVFRDEDYYHLVMELCQC---SLRDVLLRKKR--
 . | .|. .|.| |.                     | .. ||. | .        .   .  | .||.| |....|||.|     .|.|.. ...|  
CRHKKTGRIVAIKIIK---------------------EHIRREIQILKK--------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LSEHEAAIVIKQVAKAVHKMHRRGVTHRDIKPGNILLGFGESLFGNVKLADFGTSSRFSKKGSPPGMIMRGMVGTERYRAPEMSSPGRVYDE-RVD
    ..| .|. ...|...|.  .|..|. |||.|| ||||        ..|..||| . ..           . ..||  |.|||.      |.  ..|
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL-----------TTFCGTPWYMAPEVL----GYGKCKCD

VWSVGIVLYEMLFGKCAFPRLASQEIEKRLGCLEDLPMNSLDWIGISDKAKKLILHLLNIDPEKRLSLRKVKK-------HPWV
.||.|..||||| |.  ||    |.. |..|               |. || .| ..|. |||||..  .. .       |||.
WWSCGCILYEMLCGYPPFP--QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase CAMK1c-S1_d.AA Pkinase 2-267 26 8.9e-55 193.09 Pfam 19-293 (293) Show / Hide 
Range on Protein: 2-267
Range on HMM: 19-293/293
Sequence Identity: 26% (81 aa)

KRKVDGKFFACKTIRVSDYTIEDSITDDMLPDGGLREEAEAEIEALVHLSKMHSPSGGAMVPELVEVFRDEDYYHLVMELCQC-----SLRDVLL--RKK
..| .|| .|.|.|....   .  .|.  |          .||. . .|.          . .| ..|.|.|....|||.|..     .| |..   |..
HHKGTGKIVAVKIIKKRHEKSWKDQTHRRL----------SEIQIMKRLN-------HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHG

RL--SEHEAAIVIKQVAKAVHKMHRRGVTHRDIKPGNILLGFGESLFGNV----KLADFGTSSRFSKKGSPPGMIMRGMVGTERYRAPEMSSPGRVYDER
..  ||.|.  ...|.....  .|..|. |||.|| |||.   .   |..    |..||| .  |.     ..  | . .|| .|.|||    |. |. .
CFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NN---GHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK

VDVWSVGIVLYEMLFGKCAFPRL-------ASQEIEKRLGCLEDLPMNSLDWIGIS-----------------DKAKKLILHLLNIDPEKRLSLRKVKKH
||.||.|..|||||.|.  ||           | |....|.  .|. ..  |. ||                 . .|..|  .|. ||.||.. . ...|
VDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGP--PLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQH

PWV
||.
PWF
Kinase CAMK1c-S1_d.AA AGC 65-267 21 3.8e-53 134.67 In-house 96-395 (395) Show / Hide 
Range on Protein: 65-267
Range on HMM: 96-395/395
Sequence Identity: 21% (67 aa)

LVEVFRDEDY--YHLVMELCQ-----------CSLRDVLL---RKKRLSEHEAAIVIKQ-------VAKAVHKMHR-RGVTHRD-IKPGNILLGFGESLF
|   | |.|.   ..|||...           | |   |    ...|..| .| . . .       .. |.. .|. .|. ||| .|| ||||       
LHYSFQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDED----

GNVKLADFGTSSRFSKKGSPP----------------------------------------------GMIMRGMVG--TERYRAPEMSSPGRVYDERVDV
|..||.||| . .. ..|...                                              .     ..|  |  | |||.      |.  .| 
GHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDW

WS--VGIVLYEMLFGKCAFPRLASQ-------EIEKRLGCLE--------DLPMN------SLDWIGISDKAKKLILHLLNIDPEKRLS----------L
||  .|...||||.|.  |     |         ..     .        .....      . ..  .|. || || .||. ||||||            
WSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGA

RKVKKHPWV
  .|.||| 
EEIKNHPWF
Kinase CAMK1c-S1_d.AA Ciliate-E2 62-267 25 1.3e-52 178.91 In-house 94-365 (365) Show / Hide 
Range on Protein: 62-267
Range on HMM: 94-365/365
Sequence Identity: 25% (73 aa)

VPELVEVFR--DEDYYHLVMELCQC-SLRDVLL--RKKR---------LSEHEAAIVIKQVAK---------------AVHKMHRRG-VTHRDIKPGNIL
. ...|.|   |.... ||||.||  .|.| .   .|||         ..| |.. ..||...               |.. .| .. . |||||| |||
IIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENIL

LGFGESLFGNVKLADFGTSSRFSKK------GSPPGMIMRGM----------------------VGTERYRAPEMSS--P------GRVYDERVDVWSVG
.         .|..|||.| .....      ..  ...|                         .||  | |||. .  .      .  ||. .|.||.|
F---------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLG

IVLYEMLFGKCAFPRLASQEIEKRLGCLEDLPMNSL------------DWIGISDKAKKLILH----LLNIDPEKRLS-LRKVKKHPWV
..||||||||  |       ... . |  |.| .              .|  .|...| ||      .|. |||||..   ....||| 
VILYEMLFGKPPF-------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase CAMK1c-S1_d.AA CAMKL 65-267 30 6.8e-49 154.09 In-house 80-297 (297) Show / Hide 
Range on Protein: 65-267
Range on HMM: 80-297/297
Sequence Identity: 30% (70 aa)

LVEVFRDEDY------YHLVMELCQCS---LRDVLLRK----KRLSEHEAAIVIKQVAKAVHKMHRRGVTHRDIKPGNILLG-FGESLFGNVKLADFGTS
| ||. ....      ..||||.|.     | | . ..    .|..||||    .|.  ||. .|..|. |||||| ||||   | .   |.|..||| |
LYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN---NIKIIDFGFS

SRFSKKGSPPGMIMRGMVGTERYRAPEMSSPG-RVYD-ERVDVWSVGIVLYEMLFGKCAFP---------RLASQEIEKRLGCLEDLPMNSLDWIGISDK
  . ..  .||  ..   |.  | |||. . . . ||   ||.|| |..|| |..|.  |               . .|  .. .  |     |. .|  
NMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPI----WYHVS-D

AKKLILHLLNIDPEKRLSLRKVKKHPWV
.. || ..|. .|||| ..  ...|||.
CRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase CAMK1c-S1_d.AA CAMK-Unique 64-267 21 5.1e-43 139.72 In-house 80-363 (363) Show / Hide 
Range on Protein: 64-267
Range on HMM: 80-363/363
Sequence Identity: 21% (63 aa)

ELVEV----FRDED---------------YYHLVMELCQCS-LRDVLLR--------------------KKRLSE--HEAAIVIKQVAKAVHKMHRRGVT
.|...    | |..               |...|||.||.  | |....                    . ..||   ... .. ... ||  ||  .. 
KLYDWNNPIFCDRKYPLCDLIIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIV

HRDIKPGNILLGFGES------------LFGNVKLADFGTSSRFSKKGSPPGMIMRGMVGTERYRAP--------------EMSSPGRVYDERV----DV
|||.|. ||..   .             .. ..||.||| .  .. . ...  .|  |.||. | ||              |.   .. ||. .    | 
HRDLKLENIMVCYSFKDNNHHRDFPYDWSNWHIKLCDFGLCCHYNHNKMCH--MMQTMCGTPCYMAPEIVFCKNYQEMTRDEVIN-MQCYDQQCSPASDI

WSVGIVLYEMLFGKCAFPRLASQ--------EIEKRLGCLEDL-PMNSLDWIG---ISDKAKKLILHLLNIDPEKRLSLRKVKKHPWV
|| | ..|.||.|.  |    .         ||...  |  |.    .  | |   ||. || ..  ....|| .|.|.   ..|.|.
WSLGVIMYYMLCGCPPFDCECEDRDYENHDKEIFECI-CKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase CAMK1c-S1_d.AA RSK 64-267 32 6.9e-43 148.8 In-house 65-278 (278) Show / Hide 
Range on Protein: 64-267
Range on HMM: 65-278/278
Sequence Identity: 32% (71 aa)

ELVEVFRDEDYYHLVMELCQ-CSLRDVLLRKKR---LSEHEAAIVIKQVAKAVHKMHRRGVTHRDIKPGNILLGFGESLFGNVKLADFGTSSRFSKKGSP
.| ..|..|.. .|.||.|    | . |...|.   .||.||.... ....||  .| .|. |||.|| |||.   .   | .|| |||    |.|....
TLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFG----FCKQFRC

P-GMIMRGMVGTERYRAPEMSS---PGRVYDERVDVWSVGIVLYEMLFGKCAFPR---LASQEIEKRLGCLEDLPMNSLDWIGISDKAKKLILHLLNIDP
  .  .   ..|  | ||||     ... .|. .|.|| |...||||.|.  |       ..|| || .  . . ...  |  .|. || || ..|  ||
DHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGK-FSLTMPNWQYLSQEAKDLIRKMLHRDP

EKRLS-----LRKVKKHPWV
.|||.     .  .|.||| 
HKRLGCGPQDAEEIKQHPWF
Kinase CAMK1c-S1_d.AA CAMK 65-205 22 5.3e-41 129.37 In-house 103-331 (425) Show / Hide 
Range on Protein: 65-205
Range on HMM: 103-331/425
Sequence Identity: 22% (52 aa)

LVEVFRD-------------------EDYYHLVM---ELCQC-----SLRDVLLRK---------------KRLSEHEAAIVIKQVAKAVHKMHRRGVTH
| ||. |                   ......||   |.|.       | | . ..               .|..|.||. ...|.. ||| .| ... |
LYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVH

RDIKPGNILLGFGESLF-------------GNVKLADFGTSSRFSKKGS-------------------PPGMIMRGMVGTERYRA-PEMSSP--------
||.|| ||||   .. .             .|.|..||| . .| .. .                    .|  |. ..||  | | ||. .         
RDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQN

-----GRVYDERVDVWSVGIVLYEMLFGK
      . |.. .|.||.|..|| || |.
ATDEEKPYYGPKCDMWSCGVILYIMLCGY
Kinase CAMK1c-S1_d.AA Ciliate-E2-Unclassified 62-267 22 1.2e-40 138.74 In-house 83-352 (352) Show / Hide 
Range on Protein: 62-267
Range on HMM: 83-352/352
Sequence Identity: 22% (61 aa)

VPELVEVFRDEDYYHLVMELCQCSLRDVLLRK------------------KRLSEHEAA-----IVIKQVAKAVHKMHRRG-VTHRDIKPGNILLGFGES
.  ....|.|...  .|||.|.       ..|                  |...| .|.       ..|. ..  ..|. . . |||||| |||.  . .
IVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK

LFGNVKLADFGTSSRFS-----------KKGSPPGMIMRGMVGTERYR----APEMSSPGRVYDER----VDVWSVGIVLYEMLFGKCAFPRLASQE---
  ...|..||| |..             |.. .. ..|  ..|| .|     |||.   |  ||..    .|.||.|..|||||||.. |.   . .   
-NYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQ-GQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQ

------------IEKRLGCLEDLPMNSLDW----IGISDKAKKLIL----HLLNIDPEKRLSLRKVKKHPWV
            . ..  .  ..  .. .|     ..|..|| .|      .|. .|.||... ....||| 
LITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase CAMK1c-S1_d.AA STE 71-267 23 1.7e-40 140.74 In-house 108-359 (359) Show / Hide 
Range on Protein: 71-267
Range on HMM: 108-359/359
Sequence Identity: 23% (61 aa)

DEDYYHLVMELCQC-SLRDVLLRK--------------KRLSEHEAAIVIKQVAKA-VHKMHRRGVTHRDIKPGNILLGFGESLFGNVKLADFGTSSRFS
..|. ...||..   ||.|.. .|              .|..|.. |....|. |.  .  |. .. ||||||.||||         |||.|||......
NDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL---------VKLCDFGVCGQLT

KKGS-----------PPGMIMR-GMVGTERYRAPEMSSPG-----RVYDERVDVWSVGIVLYEMLFGKCAF---PRL-ASQEIEKRLGCLE---------
....             .  .|  .|||  . |||. ...       ||...|.||.|... ||. ||  .   . . |  .| .  .. .         
DSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVN

-DLP--MNSLD--------------WIGISDKAKKLILHLLNIDPEKRLSLRKVKK--HPWV
 . |   . |.                  |.. |  | . |..||.|| .  .  |  ||..
GPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase CAMK1c-S1_d.AA ULK 64-267 26 1.5e-37 128.69 In-house 82-329 (329) Show / Hide 
Range on Protein: 64-267
Range on HMM: 82-329/329
Sequence Identity: 26% (67 aa)

ELVEVFRDE--DYYHLVMELCQC-SLRDVLLRK----------KRLSEHEAAIVIKQVAKAVHKMHRRGVTHRDIKPGNILLGFGESLF--------GNV
.| ..|..   ... ..||.|.   |.. . ..          ||||| || ...|| . .   .| ... |||||| |||.  |   .        | .
KLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVL

KLADFGTSSRFSKK-GSP--PGMIMRGMV------GTERYRAPEMSS---PGRVYDER-VDVWSVGIVLYEMLFGKCA-FPRLASQEIEKRLGCLEDLPM
|.||||    |.|.  ..     .|  .|      ||  | ||.  .    .  |..  .|.||.|...||||.||.  .   ....... .  | ..| 
KIADFG----FAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPP

NS--------LDWIG------ISDKAKKLILHLLNIDPEKRLSLRKVKKHPWV
..        |..        ||.. | ||  .| .|...| |   . .|||.
PWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase CAMK1c-S1_d.AA CAMK1 65-204 32 2e-32 91.49 In-house 73-212 (276) Show / Hide 
Range on Protein: 65-204
Range on HMM: 73-212/276
Sequence Identity: 32% (48 aa)

LVEVFRDEDYYHLVMELCQC-SLRDVLLRKKRLSEHEAAIVIKQVAKAVHKMHRRGVTHRDIKPGNILLGFGESLFGNVK--LADFGTSSRFSKK-GSPP
. |.. ......|||||..   | |  . |.  .| .|. ..||...||. || .|. |||.|| |.|.  ...    .|  .|||| | .|. . .   
FYEWYESDNHFYLVMELVTGGELFDRIVEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLY-YDKDEDSKIKRSIADFGLSKIFDHDEN---

GMIMRGMVGTERYRAPEMSSP--GRVYDERVDVWSVGIVLYEMLFG
  .|  ..||  | |||.        ||  .|.||.|...| .|.|
--LMKTACGTPGYVAPEVLECKKDKPYDKACDMWSIGVITYILLCG
Kinase CAMK1c-S1_d.AA CAMK 233-267 37 5e-14 40.88 In-house 383-425 (425) Show / Hide 
Range on Protein: 233-267
Range on HMM: 383-425/425
Sequence Identity: 37% (16 aa)

WIGISDK--------AKKLILHLLNIDPEKRLSLRKVKKHPWV
| .|||         .| || ..|. |||||...  ...|||.
WDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase CAMK1c-S1_d.AA CAMK1 233-267 44 5.6e-14 36.97 In-house 241-276 (276) Show / Hide 
Range on Protein: 233-267
Range on HMM: 241-276/276
Sequence Identity: 44% (16 aa)

WIGISDK-AKKLILHLLNIDPEKRLSLRKVKKHPWV
|  |||. || .| |.|. ||.||..  .. .|||.
WDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
TyrKc CAMK1c-S1_d.AA TyrKc 3-271 17 8.4e-08 -96.5 SMART 1-280 (280) Show / Hide 
Range on Protein: 3-271
Range on HMM: 1-280/280
Sequence Identity: 17% (56 aa)

RKVDGKFF----------------ACKTIRVSDYTIEDSITDDMLPDGGLREEAEAEIEALVHL--SKMHSPSGGAMVPELVEVFRDE-------DYYHL
 . . |                  | |... .                  ||.   |.. . .|  .  .       .  |. | ...       . . .
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA-----------------REDFMREARIMCKLGGHHPN-------IVRLYGVCTQQGRNFMYIEPLMI

VMELCQC-SLRDVLLRKKR-LSEHEAAIVIKQVAKAVHKMHRRGVTHRDIKPGNILLGFGESLFGNVKLADFGTSSRFSKKG-----SPPGMIMRGMVGT
|||..   .|.| | .... |.  .      |.|.     |.... |||.   |.|.| .      || .|||  ||. . .     |     ...  |.
VMEYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGL-SRDIYDDDQQGESKDYYRKKEHKGG

E-----RYRAPEMSSPGRVYDERVDVWSVGIVLYEML-FGKCAFPR-----LASQEIEKRL--GCLEDLPMN-----SLDWIGISDKAKKLILHLLNIDP
      |  |||     ... .  |||| |....|.. .|.   |      .  ||. ...  |   . | |     .    . .|.  ....   . ||
KTMLPIRWMAPECI-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF---VCCPDEMYQIMKQCWHEDP

EKRLSLRKVKKHPWVVRNL
|.| . . .      .. .
EDRPTFSEI------HECF