Gene CAMK1c-S5_t (S.moellendorffii)
CAMK1c-S5_t
Species: S.moellendorffii
Alias: CAMK1c-S5_t
External Links:
Annotation:
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
---|---|---|---|---|---|
CAMK1c-S5_t.AA | Protein | None | 315 | None | Fasta, JSON |
CAMK1c-S5_t.NA | RNA | None | 948 | None | Fasta, JSON |
CAMK1c-S5_t.kin_dom | Protein Kinase Domain | None | 248 | None | Fasta, JSON |
Protein domains of CAMK1c-S5_t.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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S_TKc | CAMK1c-S5_t.AA | S_TKc | 20-267 | 27 | 1.6e-59 | 205.01 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 20-267 Range on HMM: 1-231/231 Sequence Identity: 27% (73 aa) YKRGKRLGCGGQGQVFALTHRGFGHKRYAGKMFRSSSEARREASIMDMLHACPGVAHLEGFVKERDGAQCYGSIVMELCGP---SLFDRLLKAGP----- |. .. .| |. |.|. .|.. ....| |. . .||| .|. . .| . .| .. . . .|||.|. .|||.. | |. YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK--EHIRREIQILKK--HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF -MCEEDAARTIKKLAETIKEIHSRGIVHRDLKPENVFLKLDAAAADDVVIGDFGMATDDPREMAQCCGTGKYLAPEVIAIKFGKSSYTE-AVDVWGLGLI . | .|.. .. ... .. .||.||.||||||||..| . |.|||.|. .||| |.||||. .|. ..|.| .| | PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL----TTFCGTPWYMAPEVL-------GYGKCKCDWWSCGCI AYELLRGCT----EWRVMDLLRAGRFPDGLFSDGAADLLRGMLAVEPRKRTTLDRVLA-------HPWI ||.| |.. . ....... |. | |..|..| ..|.|| | .|. |||. LYEMLCGYPPFPQMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | CAMK1c-S5_t.AA | CAMK | 25-267 | 19 | 6.7e-53 | 168.42 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 25-267 Range on HMM: 1-425/425 Sequence Identity: 19% (83 aa) RLGCGGQGQVFALTHRGFG-----------HKRYAGKMFRSS---------------------------------SEARREASIMDMLHA------CPGV || |. |.|. .|. . ....| |. . . ||| .|| .|.. | . TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI AHLEGFVKERDG----AQCY------------GSIVM---ELCGP-----SLFDRLLKAGP---------------MCEEDAARTIKKLAETIKEIHSRG .| . .. . | .|| |.| |||.. . |. ..|..|.| .. ... .. .||.. IKLYEVYEDPHYFKNTND-YETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN IVHRDLKPENVFLKLDAAAAD-------------DVVIGDFGMATDDPR--------------------------EMAQCCGTGKYLA-PEVIAIKFGKS ||||||||||. | . | .. | |||.|. .. | .||| | | |||. | ... IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN S----------YTEAVDVWGLGLIAYELLRGCTEWRVMD-------------------LLRAGRF--PDGLFSD-----------------------GAA . |....|.| .| | | .| |. .. . ..|.. |. ||. . MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK DLLRGMLAVEPRKRTTLDRVLAHPWI ||.|.|| |.| || |.. .|.|||. DLIRKMLQVDPEKRMTIEQCLNHPWM |
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Pkinase | CAMK1c-S5_t.AA | Pkinase | 20-267 | 25 | 8.7e-44 | 155.9 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 20-267 Range on HMM: 1-293/293 Sequence Identity: 25% (78 aa) YKRGKRLGCGGQGQVFALTHRGFGHKRYAGKMFRSSSEAR---------REASIMDMLHACPGVAHLEGFVKERDGAQCYGSIVMELCGP-----SLFDR |..|...| |. |.|. .|.| |. ..| | .. ..| .|..|| .|. .| . | ... . . .| .|||.|. .|||. YHIGRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN-HPNIVRLYDWFED--KDHIY--MVMEYCEGGLYVMDLFDY LL--KAGPM--CEEDAARTIKKLAETIKEIHSRGIVHRDLKPENVFLKLDAAAADDVVIGDFGMA----TDDPREMAQCCGTGKYLAPEVIAIKFGKSSY . . |.. |... . .. ... .. .||.||.||||||||.... . ...| |.||| | . . | ||| |.||||| | . | ISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR---GGQYY TEAVDVWGLGLIAYELLRGCTEWR------------VMDLLRAGRFPDGLF----------------------SDGAADLLRGMLAVEPRKRTTLDRVLA . .||.|..|.| ||.| | . .. .... . .... . |. . |.....|.. | || | . .| GPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQ HPWI |||. HPWF |
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Kinase | CAMK1c-S5_t.AA | AGC | 93-267 | 19 | 4.8e-39 | 97.37 | In-house | 110-395 (395) | Show / Hide |
Range on Protein: 93-267 Range on HMM: 110-395/395 Sequence Identity: 19% (59 aa) IVMELC-----------GPSLFDRLL---KAGPMCEEDAARTIKK-------LAETIKEIHS-RGIVHRD-LKPENVFLKLDAAAADDVVIGDFGMATDD .|||.. | || .| | | . || | . .. . .|| .||.||| |||||. | | . . |||... FVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDED----GHIKLTDFGLCKEG PRE-----------------------------------------------------MAQCCG--TGKYLAPEVIAIKFGKSSYTEAVDVWG--LGLIAYE ... || | |.|||.. |. |.| |. || . || MNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL--------YGKACDWWSFGLGCLMYE LLRG--------------------CTEWRVMDLLRAGRFPDGL-------------FSDGAADLLRGMLAVEPRKRTT----------LDRVLAHPWI .| | . ..|. .. .. . ||. | ||....| ..|.|| . . . .||| MLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
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Kinase | CAMK1c-S5_t.AA | Ciliate-E2a | 93-218 | 35 | 4.3e-37 | 106.73 | In-house | 76-214 (275) | Show / Hide |
Range on Protein: 93-218 Range on HMM: 76-214/275 Sequence Identity: 35% (49 aa) IVMELC-GPSLFDRLLKAGPMCEE--DAARTIKKLA-ETIKEIHSRGIVHRDLKPENVFLK-LDAAAA--DDVVIGDFGMATDD----PREMAQCCGTGK .|||.| | .|.|.. . . . || .... ...| . . .|.|.|.||||||||...| ... . |..| |||.||. .. | | ||| LVMEYCEGGELYDKIKQCKRFFEEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPG YLAPEVIAIKF--GKSSYTEAVDVWGLGLIAYELLRGCT |.||||...| . .|.. .|.| .|.| | || |.. YVAPEVLNNKEVLKHKQYDTKCDMWSCGVIFYILLCGKP |
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Kinase | CAMK1c-S5_t.AA | Ciliate-E2 | 93-267 | 21 | 1e-36 | 123.59 | In-house | 111-365 (365) | Show / Hide |
Range on Protein: 93-267 Range on HMM: 111-365/365 Sequence Identity: 21% (57 aa) IVMELC-GPSLFDRLL------------KAGPMCEEDAARTIKKLAE---------------TIKEIHSRG-IVHRDLKPENVFLKLDAAAADDVVIGDF .|||.| | .|||.. . ... |. ... .|.... ....||.. |.|||.||||... . | || LVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---------IKIIDF GMAT--DDPREMAQ--------------------------------CCGTGKYLAPEVIAIKF-----GKSSYTEAVDVWGLGLIAYELLRGCTEWRVMD |... ||.... . .||| |.|||.. | .. |....|.| || | ||.| | . . .. GLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--QQ LLRAGRFP-DGL------------------FSDGAADLLRG----MLAVEPRKRTT-LDRVLAHPWI . . . |. . ||.. || ..| || | . .| |||. QIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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Kinase | CAMK1c-S5_t.AA | CAMKL | 93-267 | 28 | 9.3e-34 | 104.99 | In-house | 98-297 (297) | Show / Hide |
Range on Protein: 93-267 Range on HMM: 98-297/297 Sequence Identity: 28% (60 aa) IVMELCGPS---LFDRLLKA----GPMCEEDAARTIKKLAETIKEIHSRGIVHRDLKPENVFLKLDAAAADDVVIGDFGMAT--DD-----PREMAQCCG .|||.|. |||.. | |.| |..| | . . . .. .||.||||||.||||. | . . | |||... .. . . .|| LVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN--NIKIIDFGFSNMYRPCIFGPGQKLKTFCG TGKYLAPEVIAIKFG--KSSYTEAVDVWGLGLIAYELLRGCTEWRV-------------MDLLRAGRFPDGLF---SDGAADLLRGMLAVEPRKRTTLDR . | |||... | |. . .||.| .| | | .. | .. . . | . . . | . ||.|.|| | | || |.. SPPYMAPEIFQ---GNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQ VLAHPWI .. ||| IMNHPWM |
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Kinase | CAMK1c-S5_t.AA | CAMK1 | 93-217 | 40 | 1.4e-30 | 86.09 | In-house | 85-213 (276) | Show / Hide |
Range on Protein: 93-217 Range on HMM: 85-213/276 Sequence Identity: 40% (53 aa) IVMELC-GPSLFDRLLKAGPMCEEDAARTIKKLAETIKEIHSRGIVHRDLKPENVFLKLDAAAADDVV--IGDFGMA--TDDPR-EMAQCCGTGKYLAPE .||||. | |||| .. | |.||....|.... .. .||.||||||||||| .. | ... | ||| . .|. | ..||| | ||| LVMELVTGGELFDRIVEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYY-DKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPE VIAIKFGKSSYTEAVDVWGLGLIAYELLRGC |.. | | |.|.|. | | | || |. VLECKK-DKPYDKACDMWSIGVITYILLCGY |
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Kinase | CAMK1c-S5_t.AA | MSK | 24-217 | 28 | 6.2e-29 | 94.93 | In-house | 2-207 (277) | Show / Hide |
Range on Protein: 24-217 Range on HMM: 2-207/277 Sequence Identity: 28% (61 aa) KRLGCGGQGQVFALTHRGFGHKR---YAGKMFR---------SSSEARREASIMDMLHACPGVAHLEGFVKERDGAQCYGSIVMELC-GPSLFDRLLKAG | || ||.| .| . .. .|. || | . .....|... |. .| . .| . .. || .|||.| |. || .. | . KVLGTGGYGKFF-ICRKCVHHDTGKLYAMKILSKATVVQKRKTAEHTQTERQCLEMCQQHPNIVNLHYAFQD----QCHTYLVMEYCNGGELFTHIRKRE PMCEEDAARTIKKLAETIKEIHSRGIVHRDLKPENVFLKLDAAAADDVVIGDFGMATDDPRE---MAQC-CGTGKYLAPEVIA-IKFGKSSYTEAVDVWG . |. .. . .| .. .|..||.||||||||. . . . |.. ||| | |.. .. |.| | |||... ... | ||.|.|. HFDESECRMIMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDNG-HVKLIDFGFARLFPQDEEWRMKSPCFTLHYMAPEMLRRGYAQDGGYDEACDWWS LGLIAYELLRGC || | |..| |. LGVILYTMLTGQ |
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Kinase | CAMK1c-S5_t.AA | RSK | 93-218 | 29 | 4.8e-28 | 99.5 | In-house | 78-210 (278) | Show / Hide |
Range on Protein: 93-218 Range on HMM: 78-210/278 Sequence Identity: 29% (40 aa) IVMELC-GPSLFDRLLKAGP---MCEEDAARTIKKLAETIKEIHSRGIVHRDLKPENVFLKLDAAAADDVVIGDFGMATD-DPR--EMAQC-CGTGKYLA ..||.| |. ||..|.| . ..|..|. . ... ... .|..||.||||||||. . . ... ||| . ... .... |.| |.| LIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMA PEVIA-IKFGKSSYTEAVDVWGLGLIAYELLRGCT ||... . ... ...|.|.| || . ||.| ||. PEMLKRAN-QQGGHDKACDWWSLGVLMYEMLTGCP |
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Kinase | CAMK1c-S5_t.AA | DCAMKL | 102-216 | 33 | 8.9e-24 | 70.37 | In-house | 102-215 (279) | Show / Hide |
Range on Protein: 102-216 Range on HMM: 102-215/279 Sequence Identity: 33% (40 aa) LFDRLLKAGPMCEEDAARTIKKLAETIKEIHSRGIVHRDLKPENVFLKLDAAAADDVVIGDFGMATDDPR---EMAQCCGTGKYLAPEVIAIKFGKSSYT ||| . . . | |||. . .|.. .| .|...|||||.|||| .. . . .||| |. .. . ||| | |||... . | LFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILM----ETGYG EAVDVWGLGLIAYELLRG ||.| .| | | || | CKVDIWAAGVILYILLCG |
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Kinase | CAMK1c-S5_t.AA | RSK | 93-218 | 36 | 9.4e-23 | 78.16 | In-house | 78-203 (271) | Show / Hide |
Range on Protein: 93-218 Range on HMM: 78-203/271 Sequence Identity: 36% (48 aa) IVMELC-GPSLFDRLLKAGPMCEEDAARTIKKLAETIKEIHSRGIVHRDLKPENVFLKLDAAAADDVVIGDFGMA--TDDPREMAQC-CGTGKYLAPEVI ..|... | ||||||| . ..|.... .| . || |||||||||||. . . . .. . | ||| | | .|. |.| |.||||. MIMDFMRGGDLFDRLLKQKMFSEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVL AIKFGKSSYTEAVDVWGLGLIAYELLRGCT . ...|.|.| .| . || | ||| K----RQGHDQACDWWSFGVLMYEMLTGCT |
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Kinase | CAMK1c-S5_t.AA | CAMK1 | 237-267 | 50 | 7.6e-11 | 27.69 | In-house | 245-276 (276) | Show / Hide |
Range on Protein: 237-267 Range on HMM: 245-276/276 Sequence Identity: 50% (16 aa) SDG-AADLLRGMLAVEPRKRTTLDRVLAHPWI ||. | |....|| |.| || | . .|.|||| SDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI |
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Kinase | CAMK1c-S5_t.AA | DCAMKL | 237-267 | 48 | 2.3e-10 | 27.88 | In-house | 249-279 (279) | Show / Hide |
Range on Protein: 237-267 Range on HMM: 249-279/279 Sequence Identity: 48% (15 aa) SDGAADLLRGMLAVEPRKRTTLDRVLAHPWI ||.| || . || |.| || | ...|||. SDSAKDLISHMLQVDPEKRYTAEQIMQHPWV |
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Kinase | CAMK1c-S5_t.AA | RSK | 237-267 | 38 | 7.6e-09 | 27.94 | In-house | 236-271 (271) | Show / Hide |
Range on Protein: 237-267 Range on HMM: 236-271/271 Sequence Identity: 38% (14 aa) SDGAADLLRGMLAVEPRKRTTL-----DRVLAHPWI || | ||||.|| . | .| . ... |||. SDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF |
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Kinase | CAMK1c-S5_t.AA | RSK | 237-267 | 36 | 7.8e-09 | 28.8 | In-house | 243-278 (278) | Show / Hide |
Range on Protein: 237-267 Range on HMM: 243-278/278 Sequence Identity: 36% (13 aa) SDGAADLLRGMLAVEPRKRTT-----LDRVLAHPWI |. | ||.|.|| ..| || . ......|||. SQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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Kinase | CAMK1c-S5_t.AA | TyrKc | 20-267 | 22 | 8.8e-09 | -80.67 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 20-267 Range on HMM: 1-280/280 Sequence Identity: 22% (68 aa) YKRGKRLGCGGQGQVFALTHRGFGHKRYAGKMFRSSSEAR----REASIMDML-HACPGVAHLEGFVKER------DGAQCYGSIVMELCGP-SLFDRLL . || ||.| |.|. | . | || .... | |||.|| .| | . | | . . .. . ||||.. .| |.| ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLM---IVMEYMPHGDLKDYLR KAGP-MCEEDAARTIKKLAETIKEIHSRGIVHRDLKPENVFLKLDAAAADDVVIGDFGMATDDPRE--------MAQC----CGTG----KYLAPEVIAI | .| | .| |. .||....|||| |. .. . | |.|||.. | . . .| . . .|||.| KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-- KFGKSSYTEAVDVWGLGLIAYELL-------RG-----CTEWRVMDLLRAG---RFPDGL-------FSDGAADLLRGMLAVEPRKRTTLDRVLAHPWI ..|| .|.. ||| | .|.. | .. .|. ....| . |. .| .. . . .| .| | . | . NYGK--FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF |
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Kinase | CAMK1c-S5_t.AA | Ciliate-E2a | 236-267 | 40 | 1.3e-07 | 18.51 | In-house | 244-275 (275) | Show / Hide |
Range on Protein: 236-267 Range on HMM: 244-275/275 Sequence Identity: 40% (13 aa) FSDGAADLLRGMLAVEPRKRTTLDRVLAHPWI .|. . ||...|| . | || | | ||| CSKECKDLMKKMLEKDPKKRITAQQALNHPWF |
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Kinase | CAMK1c-S5_t.AA | MSK | 236-267 | 34 | 5e-06 | 16.44 | In-house | 246-277 (277) | Show / Hide |
Range on Protein: 236-267 Range on HMM: 246-277/277 Sequence Identity: 34% (11 aa) FSDGAADLLRGMLAVEPRKRTTLDRVLAHPWI .| | ||....| . | || ... .|| |. MSPDAKDLIQWLLTKDPKKRLGMNDLRAHEWK |
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Kinase | CAMK1c-S5_t.AA | CAMKL | 20-69 | 27 | 0.037421 | 2.5 | In-house | 1-70 (297) | Show / Hide |
Range on Protein: 20-69 Range on HMM: 1-70/297 Sequence Identity: 27% (19 aa) YKRGKRLGCGGQGQVFALTHRGFGHKRYAGKMFRSSSEA--------------------RREASIMDMLH |. || ||.|. |.| ||. . ...| |. . |||..|| ||. YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLN |
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Kinase | CAMK1c-S5_t.AA | Ciliate-E2 | 20-40 | 33 | 0.068237 | 2.26 | In-house | 1-21 (365) | Show / Hide |
Range on Protein: 20-40 Range on HMM: 1-21/365 Sequence Identity: 33% (7 aa) YKRGKRLGCGGQGQVFALTHR || | .| |..|.|. ... YKFIKKIGQGNFGSVYKCKVW |