Gene CAMK1c-S5_q (S.moellendorffii)

CAMK1c-S5_q

Species: S.moellendorffii
Alias: CAMK1c-S5_q
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK1
Subfamily: CAMK1c

Sequence

Name Sequence Type Origin Length Description Download
CAMK1c-S5_q.AA Protein None 310 None Fasta, JSON
CAMK1c-S5_q.NA RNA None 933 None Fasta, JSON
CAMK1c-S5_q.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of CAMK1c-S5_q.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc CAMK1c-S5_q.AA S_TKc 17-269 27 2.4e-56 194.41 SMART 1-231 (231) Show / Hide 
Range on Protein: 17-269
Range on HMM: 1-231/231
Sequence Identity: 27% (75 aa)

YRRGEKLGSGGEGQVYLLSARRRAGKKYAGKLVESMRNGENEARLMSKLRVCPGVVAFEDFVREREGGRCYGTIVMELCGP---SLAERLIHGGA-----
|. ..|.|.|. |.||.   ..  |...| | .   .. ..| ....|   .| .| . |. ..   .. |  .|||.|.    .| ... . |      
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK--EHIRREIQILKK--HHPNIVKLYDVFQD---DHLY--MVMEYCDGDLGDLFDYIKKRGRHGLRF

-VTEEEAAKTIKTLAETLKWMHSRGVVHRDLKPHNIFERLNATAVDEVVIGDFGMATDKQWDMRQYCGTAKYMAPEVVAVKSDGARGPRASYTA-AVDVW
  .| .|.. .. ... |. .||.|..|||||| ||.  |.     .. |.|||.|.      . .|||  ||||||.            .|.  ..|.|
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENIL--LDE----HIKICDFGLARQL----TTFCGTPWYMAPEVL------------GYGKCKCDWW

GLGVIAYELLSGYR----SRVEFDFLRAGAFPSDLASCEAEDLIQGMLAVEQSKRVTLDAVLA-------HPWI
 .|.| ||.|.||       . |. ..         | || |.|...| .. .|| |   .|.       |||.
SCGCILYEMLCGYPPFPQMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase CAMK1c-S5_q.AA Pkinase 17-219 29 1.4e-42 151.63 Pfam 1-209 (293) Show / Hide 
Range on Protein: 17-219
Range on HMM: 1-209/293
Sequence Identity: 29% (67 aa)

YRRGEKLGSGGEGQVYLLSARRRAGKKYAGKLVESMRNGE---------NEARLMSKLRVCPGVVAFEDFVREREGGRCYGTIVMELCGP-----SLAER
|..|.|.|||. |.||.   ..  ||..| | ..  .. .         .|...| .|. .| .| . |....  ....|  .|||.|.      .|...
YHIGRKIGSGSFGCVYKCH-HKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN-HPNIVRLYDWFED--KDHIY--MVMEYCEGGLYVMDLFDY

LI--HGGAV--TEEEAAKTIKTLAETLKWMHSRGVVHRDLKPHNIFERLNATAV-DEVVIGDFGMA----TDKQWDMRQYCGTAKYMAPEVVAVKSDGAR
.    .|..  .|.|. . .. ... |. .||.|..|||||| ||.   |   . . | |.||| |    . ..  |  .|||  ||||||.        
ISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-------

GPRASYTAAVDVWGLGVIAYELLSGY
  .  |. .||.|..|.| ||.|.|.
-GGQYYGPKVDMWSCGCILYEMLCGR
Kinase CAMK1c-S5_q.AA CAMK 22-219 19 3.2e-36 113.7 In-house 1-331 (425) Show / Hide 
Range on Protein: 22-219
Range on HMM: 1-331/425
Sequence Identity: 19% (65 aa)

KLGSGGEGQVYLLSARRRAG-----------KKYAGKLVE---------------------------------SMRNGENEARLMSKLRV------CPGV
.||.|. |.|.|   ..  |           .|.| | ..                                 ...| ..| ..|.||.        | .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VAFEDFVRERE---------GGRC-------YGTIVM---ELCGP-----SLAERLIHG---------------GAVTEEEAAKTIKTLAETLKWMHSRG
. . ..   ..           ..       .  .||   |.|        | ....                 | .||.||.. .. ... .. .||..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VVHRDLKPHNIFERLNATAVD-------------EVVIGDFGMATDKQW--------------------------DMRQYCGTAKYMA-PEVVAVKSDGA
.||||||| ||    | .  |              . | |||.|. ..                            |. .|||  ||| |||.  |. ..
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

RGPRAS-------YTAAVDVWGLGVIAYELLSGY
 .   .       |. ..|.| .||| | .|.||
MQ-N-ATDEEKPYYGPKCDMWSCGVILYIMLCGY
Kinase CAMK1c-S5_q.AA Ciliate-E2 17-269 18 9.8e-34 113.17 In-house 1-365 (365) Show / Hide 
Range on Protein: 17-269
Range on HMM: 1-365/365
Sequence Identity: 18% (72 aa)

YRRGEKLGSGGEGQVYLLSARRRAGK-----------------KYAGKLVESMRNGENE-ARLMSKLRVC---------------------PGVVAFEDF
|   .|.|.|. |.||. . ..   .                 |...|...  .. .|.   ........                     | .. . ..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

VREREGGRCYGTIVMELC-GPSLAERLI------------HGGAVTEEEAAKTIKTLAE---------------TLKWMHSRG-VVHRDLKPHNIFERLN
  |     .|  .|||.| | .| ....              .  ||.|... .| ...                |. .||.. ..|||.|| ||.    
FQEKDDNNIY--LVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---

ATAVDEVVIGDFGMATDKQ-------------WDMRQY----------------------CGTAKYMAPEVVAVKSDGARGPRASYTAAVDVWGLGVIAY
      . | |||.... .             | |                         |||. |||||..  |...    .  |. ..|.| |||| |
------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILY

ELLSGYRSRVEFDFLRAGAFPSDLASC-------------------EAEDLIQG----MLAVEQSKRVT-LDAVLAHPWI
|.|.|..    ..    . .  . . .                   |. |||.     || ....|| |  . .| |||.
EMLFGKPPF--QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase CAMK1c-S5_q.AA PSK 90-269 31 7.8e-31 95.52 In-house 73-258 (258) Show / Hide 
Range on Protein: 90-269
Range on HMM: 73-258/258
Sequence Identity: 31% (62 aa)

IVMEL-CGPSLAERLIHGGAVTEEEAAKTIKTLAETLKWMHSRGVVHRDLKPHNIFERLNATAVDE--VVIGDFGMA----TDKQWDMRQYCGTAKYMAP
.|||.  |  .  |..  |  ||..| .  . ... ....|. .. |||||| |    | .   .|  ..| |||.|    .   | |.  |||  | ||
MVMEMATGGEMFDRIVAKGRFTERDATRVLQMVLDGMRYLHALRITHRDLKPENL---LYYHPGNESKIMITDFGLAYQRKKSNDWMMKTTCGTPEYIAP

EVVAVKSDGARGPRASYTAAVDVWGLGVIAYELLSG------------YRSRVEFDFLRAGAFPSDLASCEAEDLIQGMLAVEQSKRVTLDAVLAHPWI
||           |  || .|| | .||||| |.||            ||  .   .   | . ... |  | | |  .| ..|..| |  . . |||.
EVLL---------RKPYTQSVDMWAVGVIAYILMSGIMPFDDDCRTRLYRHILTGKYNYYGQPWPSV-SHLAKDFIDKLLEINQGERMTASQAMKHPWV
Kinase CAMK1c-S5_q.AA MSK 90-218 34 4.7e-29 95.36 In-house 78-206 (277) Show / Hide 
Range on Protein: 90-218
Range on HMM: 78-206/277
Sequence Identity: 34% (47 aa)

IVMELC-GPSLAERLIHGGAVTEEEAAKTIKTLAETLKWMHSRGVVHRDLKPHNI-FERLNATAVDEVVIGDFGMA----TDKQWDMRQYCGTAKYMAPE
.|||.| |. | ... . .  .|.|..  .  |   .. ||..|..|||||| || |.  .  .  .|.. ||| |    .|..| |  .|.|  |||||
LVMEYCNGGELFTHIRKREHFDESECRMIMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDNG--HVKLIDFGFARLFPQDEEWRMKSPCFTLHYMAPE

VVAVKSDGARGPRASYTAAVDVWGLGVIAYELLSG
....    .  .   | .|.|.|.|||| |..|.|
MLRR----GYAQDGGYDEACDWWSLGVILYTMLTG
Kinase CAMK1c-S5_q.AA CAMK1 110-219 37 4.7e-29 81.56 In-house 106-213 (276) Show / Hide 
Range on Protein: 110-219
Range on HMM: 106-213/276
Sequence Identity: 37% (44 aa)

TEEEAAKTIKTLAETLKWMHSRGVVHRDLKPHNIFERLNATAVDE--VV--IGDFGMA--TDKQWD-MRQYCGTAKYMAPEVVAVKSDGARGPRASYTAA
||..|....| ... .. |||.|.||||||| |.   | ..  ..  ..  | ||| .  .| . . | . |||  |.||||.. |.         |  |
TEKDARHIMKQILSAVEYMHSKGIVHRDLKPENL---LYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKK------DKPYDKA

VDVWGLGVIAYELLSGY
.|.|. ||| | || ||
CDMWSIGVITYILLCGY
Kinase CAMK1c-S5_q.AA STE 17-269 19 2.6e-27 93.58 In-house 1-359 (359) Show / Hide 
Range on Protein: 17-269
Range on HMM: 1-359/359
Sequence Identity: 19% (72 aa)

YRRGEKLGSGGEGQVYLLSARR-----RAGKK---------YAGKLVE----------------------SMRNGENEARLMSKLRV-CPGVVAFEDFVR
... ||.|.|. |.||.   .      . |..         .| | ..                       | . ..| ..|.|..  .| .| . .   
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

ER---EGGRCYGTIVMELCG-PSLAERLIHG--------------GAVTEEEAAKTIKTLAET-LKWMHSRGVVHRDLKPHNIFERLNATAVDEVVIGDF
     .. . .  |.||...  || . . |               . . |.. |. .. . .  |.  || ...|||.|| ||.          | . ||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL---------VKLCDF

GMATDKQWDMR-------------------QYCGTAKYMAPEVVAVKSDGARGPRASYTAAVDVWGLGVIAYELLSGYRSRVEFDFLRA-----------
| ..  . .|.                     .||  .|||||.   . | |  .  |.. .|.| ||  . |.. |     ..  .||           
GVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-R--DKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQ

----------GAFP--SD-------------------LASCEAEDLIQGMLAVEQSKRVTLDAVLA--HPWI
          |  |   |                     | |  | |.  |  . .|| | .  |   ||.|
QQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase CAMK1c-S5_q.AA RSK 90-269 29 2.3e-26 91.2 In-house 78-271 (271) Show / Hide 
Range on Protein: 90-269
Range on HMM: 78-271/271
Sequence Identity: 29% (60 aa)

IVMELC-GPSLAERLIHGGAVTEEEAAKTIKTLAETLKWMHSRGVVHRDLKPHNIFERLNATAVDEVVIGDFGMATDKQWDMRQY-----CGTAKYMAPE
..|... |  |  ||   .  .|.|..    ..| ..   || |.||||||| ||         . . | ||| |  ||   .       |.|| |||||
MIMDFMRGGDLFDRLLKQKMFSEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFA--KQLRDENGMLMTFCYTANYMAPE

VVAVKSDGARGPRASYTAAVDVWGLGVIAYELLSGY-------RSRVEFDFLRAGAFP-------SDLASCEAEDLIQGMLAVEQSKRVTL-----DAVL
|.       .|    ...|.|.| .||. || |.|.       | . .   .|..           |  | || ||. .|| .   .|..        ..
VLK-----RQG----HDQACDWWSFGVLMYEMLTGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIK

AHPWI
 |||.
QHPWF
Kinase CAMK1c-S5_q.AA RSK 90-220 30 3.1e-26 93.07 In-house 78-210 (278) Show / Hide 
Range on Protein: 90-220
Range on HMM: 78-210/278
Sequence Identity: 30% (42 aa)

IVMELC-GPSLAERLIHGGA---VTEEEAAKTIKTLAETLKWMHSRGVVHRDLKPHNIFERLNATAVDEVVIGDFGMATDKQWDMRQ----YCGTAKYMA
..||.| |. | ..| . .     .|.||.  . ... ... .|..|..|||||| ||          .... ||| .  .  |. |    .|.|. |||
LIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMA

PEVVAVKSDGARGPRASYTAAVDVWGLGVIAYELLSGYR
||....    |  ..  ...|.|.| |||. ||.|.|..
PEMLKR----AN-QQGGHDKACDWWSLGVLMYEMLTGCP
Kinase CAMK1c-S5_q.AA Aur 110-219 33 1.3e-24 61.44 In-house 99-198 (257) Show / Hide 
Range on Protein: 110-219
Range on HMM: 99-198/257
Sequence Identity: 33% (38 aa)

TEEEAAKTIKTLAETLKWMHSRGVVHRDLKPHNIFERLNATAVDEVVIGDFGMATDKQ-WDMRQ-YCGTAKYMAPEVVAVKSDGARGPRASYTAAVDVWG
.|..||| .. ... |. .||....|||.|| ||   |.    ... |.||| .. ..  ..|. .|||  ||.||.|          . ..   ||.| 
DEQRAAKYMYQICNALDYCHSKNIIHRDIKPENI---LLDQCNGNIKICDFGWSVHCPNNNRRMTFCGTLDYMPPEMVE---------GQMHDHKVDIWC

LGVIAYELLSGY
|||..|||..|.
LGVLCYELCHGC
Kinase CAMK1c-S5_q.AA MAPKAPK 17-219 28 1.4e-24 72.63 In-house 1-215 (292) Show / Hide 
Range on Protein: 17-219
Range on HMM: 1-215/292
Sequence Identity: 28% (64 aa)

YRRGEKLGSGGEGQVYLLSARRRAGKKYAGKLVESM-----RNGENEARLMSKLRVCPGVVAFEDFVRE--REGGRCYGTIVME-LCGPSLAERLIH--G
   .|.||.|  |.| .    .| |..|| |..|           .| .| ..   .| .|   |.  .   .  . |  .||| . | .| ..      
KLWKEVLGEGIYGKV-QTCVHKRTGQEYAVKILEDQPGHSRQKARREVELHWHCQGHPNIVQIIDWFENMYQFDKCFY--LVMECMEGGELFQHIQQRGH

GAVTEEEAAKTIKTLAETLKWMHSRGVVHRDLKPHNI-FERLNATAVDEVVIGDFGMATD-------KQW----DMRQYCGTAKYMAPEVVAVKSDGARG
.. ||.||.. .|  .. .. .||..  |||||| || ..  |  ..  | ..||| |          .     ..   |.|. ||||||| . .     
KHFTEREASQIMKDICSAVDFLHSMNIAHRDLKPENILCTDTNHNCP--VKLCDFGFAKEIHLNHDCTTPITTPELMTPCYTPYYMAPEVVGAFK-----

PRASYTAAVDVWGLGVIAYELLSGY
    |    | | |||| | .|.||
EAHTYDKSCDMWSLGVIMYIMLCGY
Kinase CAMK1c-S5_q.AA Aur 241-269 48 3.3e-13 30.68 In-house 229-257 (257) Show / Hide 
Range on Protein: 241-269
Range on HMM: 229-257/257
Sequence Identity: 48% (14 aa)

EAEDLIQGMLAVEQSKRVTLDAVLAHPWI
|| |||.. | .. ..|.||| ...||||
EAKDLISKILQHDPKQRMTLDQIMNHPWI
Kinase CAMK1c-S5_q.AA CAMK 235-269 43 8.3e-13 36.89 In-house 387-425 (425) Show / Hide 
Range on Protein: 235-269
Range on HMM: 387-425/425
Sequence Identity: 43% (17 aa)

SDL----ASCEAEDLIQGMLAVEQSKRVTLDAVLAHPWI
||      | |. |||..|| |. .|| |.. .|.|||.
SDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase CAMK1c-S5_q.AA MAPKAPK 239-269 45 2.9e-09 24.35 In-house 262-292 (292) Show / Hide 
Range on Protein: 239-269
Range on HMM: 262-292/292
Sequence Identity: 45% (14 aa)

SCEAEDLIQGMLAVEQSKRVTLDAVLAHPWI
|.|| |||  .| .. ..| |  .|..||||
SEEAKDLIRKLLRRDPTQRLTIEQVMNHPWI
Kinase CAMK1c-S5_q.AA CAMK1 241-269 51 5.2e-08 19.32 In-house 248-276 (276) Show / Hide 
Range on Protein: 241-269
Range on HMM: 248-276/276
Sequence Identity: 51% (15 aa)

EAEDLIQGMLAVEQSKRVTLDAVLAHPWI
|| |.| .|| |. .|| | . .|.||||
EAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase CAMK1c-S5_q.AA RSK 239-269 36 9.7e-08 24.76 In-house 243-278 (278) Show / Hide 
Range on Protein: 239-269
Range on HMM: 243-278/278
Sequence Identity: 36% (13 aa)

SCEAEDLIQGMLAVEQSKRVT-----LDAVLAHPWI
| || |||..|| .. .|| .     .. ...|||.
SQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase CAMK1c-S5_q.AA TyrKc 17-269 19 1.1e-07 -98.32 SMART 1-280 (280) Show / Hide 
Range on Protein: 17-269
Range on HMM: 1-280/280
Sequence Identity: 19% (61 aa)

YRRGEKLGSGGEGQVYLLSARRRAGKKYAGKLVESMRNGE----NEARLMSKL-RVCPGVVAFEDFVRERE------GGRCYGTIVMELCGP-SLAERL-
 . |.|||.|  |.||.  ..     . | | . .    .    .|||.|.||    | .|..   ... .      .  .   ||||..   .| ..| 
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLM---IVMEYMPHGDLKDYLR

IHGGAVTEEEAAKTIKTLAETLKWMHSRGVVHRDLKPHNIF--ERLNATAVDEVVIGDFGMATDKQWD------MRQY------CGT----AKYMAPEVV
 |.. .. ..  .     |.     ||....||||   |.   |..       | |.|||.. |   |         |      .|      . ||||. 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

AVKSDGARGPRASYTAAVDVWGLGVIAYELLS-GYRSRVE-----------FDFLRAGAFPSDLAS--------CEAE--DLIQGMLAVEQSKRVTLDAV
             .| . |||  ||  .|... |     .           . ....|  .   ..        | .|  ....   . . ..| |  ..
---------NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI

LAHPWI
  |  .
--HECF
Kinase CAMK1c-S5_q.AA MSK 238-269 37 3e-06 16.93 In-house 246-277 (277) Show / Hide 
Range on Protein: 238-269
Range on HMM: 246-277/277
Sequence Identity: 37% (12 aa)

ASCEAEDLIQGMLAVEQSKRVTLDAVLAHPWI
.| .| ||||..| .  .|| ...  .|| |.
MSPDAKDLIQWLLTKDPKKRLGMNDLRAHEWK
Kinase CAMK1c-S5_q.AA Pkinase 241-269 37 8e-06 21.69 Pfam 265-293 (293) Show / Hide 
Range on Protein: 241-269
Range on HMM: 265-293/293
Sequence Identity: 37% (11 aa)

EAEDLIQGMLAVEQSKRVTLDAVLAHPWI
|. |.| ..|..  .|| | . .| |||.
ECKDFIKWCLCKDPKKRPTAEQILQHPWF