CAMK1c-S2_a

Species: S.moellendorffii
Alias: CAMK1c-S2_a
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK1
Subfamily: CAMK1c

Sequence

Name Sequence Type Origin Length Description Download
CAMK1c-S2_a.AA Protein None 289 None Fasta, JSON
CAMK1c-S2_a.NA RNA None 870 None Fasta, JSON
CAMK1c-S2_a.kin_dom Protein Kinase Domain None 187 None Fasta, JSON

Protein domain

Protein domains of CAMK1c-S2_a.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc CAMK1c-S2_a.AA S_TKc 31-283 24 2.6e-34 121.2 SMART 1-231 (231) Show / Hide
Range on Protein: 31-283
Range on HMM: 1-231/231
Sequence Identity: 24% (67 aa)

GGEDNRIRIGGQASVFKVLRRKDGQAFAVKTILDSGDGYFDREDRTLATLGYSNTDRLPDRKQVRD-----LVLELCDY---NLYERISLKGV------L
    . |  |. ..|.|.  .|.|. .|.| |       . || . |      . . .   . | .     .|.|.||    .|...|  .|       .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK----HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

GEHEAAKIIAPLAKTLGQVHEEGFIHCDVKPENVLLADRESNHDCCVPKLCDFGLACCMTNPWRVSGIGTWVYMAPEAMLGDGCYTP-AVDVWGLGMVLY
 | .|..... ... |   |. |.||.|.||||.|| .        . |.||||||. .      . .||  ||||| .     |.. ..|.| .| .||
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--------HIKICDFGLARQL-----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILY

HCLTARTPFLKLRREETRRISESVISSGSGVHHGVFCWDGISDGARDLIRGMTA----NRLVIKEILN-------HEWI
 .|. ..||      .  .. . .                 |. |.|.||..      .|. . |.|.       |.|.
EMLCGYPPFP-----QMQMMFKKIG----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase CAMK1c-S2_a.AA CAMK 97-283 21 7.7e-34 105.89 In-house 134-425 (425) Show / Hide
Range on Protein: 97-283
Range on HMM: 134-425/425
Sequence Identity: 21% (62 aa)

LVL---ELCDYN-----LYERISLK---------------GVLGEHEAAKIIAPLAKTLGQVHEEGFIHCDVKPENVLLADRESNHDC-----------C
.|.   |.|.       |...|  .               | . |.||....  ..  .   |. . .|.| ||||.|| |.... |            .
MVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNN

VPKLCDFGLACCMTN--------------------------PWRVSGIGTWVYMA-PEAMLG-------------DGCYTPAVDVWGLGMVLYHCLTART
  |..|||.|. ..                           . . .  ||  ||| ||  .|                |.|..|.| .| .|| .|. . 
NIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTF-CGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYP

PFLKLRREETR-------RISESVISSGSGVHHGVFC-------------WDGISDG--------ARDLIRGMTA----NRLVIKEILNHEWI
||    ..|..        ..|      .|  .                 ||.|||         ..||||.|      .|. |...|||.|.
PFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM

Kinase CAMK1c-S2_a.AA RSK 106-283 29 8.3e-32 112.0 In-house 88-278 (278) Show / Hide
Range on Protein: 106-283
Range on HMM: 88-278/278
Sequence Identity: 29% (59 aa)

LYERISLKGV---LGEHEAAKIIAPLAKTLGQVHEEGFIHCDVKPENVLLADRESNHDCCVPKLCDFGLACCMTNP---WRVSGIGTWVYMAPEAML---
|..... ..    . |.||. ..| .....   |. |.|| | ||||.|..|.. |.     ||.|||... . .    |  . ..|  |||||      
LFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHI--KLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRAN

GDGCYTPAVDVWGLGMVLYHCLTARTPFLK---LRREET-RRISESVISSGSGVHHGVFCWDGISDGARDLIRGM----TANRLV-----IKEILNHEWI
..| .. |.|.| || ..|  || ..||       |.|. .|| .  .| ...       |. .|. |.||||.|     ..||      ..||..|.|.
QQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPN------WQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF





Kinase CAMK1c-S2_a.AA Pkinase 97-283 27 3.2e-29 104.38 Pfam 77-293 (293) Show / Hide
Range on Protein: 97-283
Range on HMM: 77-293/293
Sequence Identity: 27% (60 aa)

LVLELCDY-----NLYERIS--LKGVL--GEHEAAKIIAPLAKTLGQVHEEGFIHCDVKPENVLLADRESNHDCCVPKLCDFGLACCM--TNPWRVSGIG
.|.|.|.       |...||   .|..   |.|. ...  ... |   |..|.||.|.||||.|. ..  . . || |.||||||...   |.   .  |
MVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA-CV-KICDFGLAKQFDYNNS-MTTFCG

TWVYMAPEAMLGDGCYTPAVDVWGLGMVLYHCLTARTPFL-KLRREETRRISESVISSGSGVHHGVFCWDGIS-------------------DGARDLIR
|  |||||  .|.  |.|.||.|..| .||  |. |.||  .   ... .    .|    |      ..  .|                   . ..|.|.
TPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIK

GM----TANRLVIKEILNHEWI
..     . |. ...||.|.|.
WCLCKDPKKRPTAEQILQHPWF

Kinase CAMK1c-S2_a.AA MSK 97-224 37 1.8e-26 86.46 In-house 78-210 (277) Show / Hide
Range on Protein: 97-224
Range on HMM: 78-210/277
Sequence Identity: 37% (51 aa)

LVLELCDYN-LYERISLKGVLGEHEAAKIIAPLAKTLGQVHEEGFIHCDVKPENVLLADRESNHDCCVPKLCDFGLACCMTNP--WRVSG-IGTWVYMAP
||.|.|  . | ..|. ..   |.|.. |.. |   . . |..|.|| | ||||.|..|.|.|      || |||.|.  ..   ||     .|  ||||
LVMEYCNGGELFTHIRKREHFDESECRMIMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDNGHV---KLIDFGFARLFPQDEEWRMKSPCFTLHYMAP

EAML----GDGCYTPAVDVWGLGMVLYHCLTARTPF
|       .|| | .|.|.|.|| .||  || . ||
EMLRRGYAQDGGYDEACDWWSLGVILYTMLTGQVPF

Kinase CAMK1c-S2_a.AA RSK 106-283 32 1.4e-24 84.73 In-house 88-271 (271) Show / Hide
Range on Protein: 106-283
Range on HMM: 88-271/271
Sequence Identity: 32% (62 aa)

LYERISLKGVLGEHEAAKIIAPLAKTLGQVHEEGFIHCDVKPENVLLADRESNHDCCVPKLCDFGLA--CCMTNPWRVSGIGTWVYMAPEAMLGDGCYTP
|  |.. .... | |.. . | .|...   |. | .| | ||||.|..| . | ..   |.||||.|      |    .  .|  ||||| .| .  .. 
LFDRLLKQKMFSEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHI--KICDFGFAKQLRDENGMLMTFCYTANYMAPE-VLKRQGHDQ

AVDVWGLGMVLYHCLTARTPFLKLRREETRRISESVISSGSGV---HHGVFCWDGISDGARDLIRGM----TANRLVI-----KEILNHEWI
|.|.| .| ..|  || .|||    |...  |       ..|     ||.  || ||| | ||.|.|     .|||       ..|..| |.
ACDWWSFGVLMYEMLTGCTPFQNKPRDTPMNI---IQRIKLGMFSMTHGN--WDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF

Kinase CAMK1c-S2_a.AA Ciliate-E2 97-283 19 1.3e-23 77.92 In-house 111-365 (365) Show / Hide
Range on Protein: 97-283
Range on HMM: 111-365/365
Sequence Identity: 19% (54 aa)

LVLELCDY-NLYERISLK-----------GVLGEHEAAKIIAPLAK---------------TLGQVHEEG-FIHCDVKPENVLLADRESNHDCCVPKLCD
||.|.|.. .|...|  .           . . | |...|.. ...                |   |...  || | ||||.|.           .|..|
LVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----------IKIID

FGLA------------CCMTNPWRVSG----------------------IGTWVYMAPEAMLGDGC--------YTPAVDVWGLGMVLYHCLTARTPFLK
|||.            . . . .   .                      .||  |||||   | .         |. ..|.| ||..|| .|. ..||  
FGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--

LRREETRRISESVISSGSGVH-------HGVFC----WDGISDGARDLIRG--------MTANRLV-IKEILNHEWI
       .. .    . .  .         . |    |. .|. . |||.            .|.  ...||||.|.
------QQQIKQCKIDFPCPEWQKDTQCI-Q-CKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase CAMK1c-S2_a.AA CMGC 97-211 20 4.1e-21 65.29 In-house 132-322 (513) Show / Hide
Range on Protein: 97-211
Range on HMM: 132-322/513
Sequence Identity: 20% (41 aa)

LVLELCDYNLYERISLKG---------VLGEHE------------AAKII------APLAKTLG--QVHEEG--FIHCDVKPENVLLADRESNHDCCVP-
|| |..|..||. |  .           | | .              ...        . . |     |  .  .||.| ||||.|.     ||.| .. 
LVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILI-----NHNCELIT

------------------KLCDFGLACCMTNP-----------------------WRVSGIGTWVYMAPEAMLGDGCYT---------PAVDVWGLG
                  |.||||||.   ..                          . . |  | ||| .||.. ||         ...|.|..|
RMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVG

Kinase CAMK1c-S2_a.AA CAMKL 97-224 29 1.4e-20 62.31 In-house 98-236 (297) Show / Hide
Range on Protein: 97-224
Range on HMM: 98-236/297
Sequence Identity: 29% (42 aa)

LVLELCDYN---LYERISLK----GVLGEHEAAKIIAPLAKTLGQVHEEGFIHCDVKPENVLLADRESNHDCCVPKLCDFGLACCMT------NPWRVSG
||.|.|.     |...|  .    | . |||| ..   .   .   |. | .| | ||||.|| .. .|    . |..|||..  ..      .      
LVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN----NIKIIDFGFSNMYRPCIFGPGQKLKTF

IGTWVYMAPEAMLG--DGCYTPAVDVWGLGMVLYHCLTARTPF
 |.  |||||  .|  .  . |.||.| .| .||  .. . ||
CGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPF

Kinase CAMK1c-S2_a.AA Ciliate-E2-Unclassified 97-283 19 1.8e-20 67.77 In-house 98-352 (352) Show / Hide
Range on Protein: 97-283
Range on HMM: 98-352/352
Sequence Identity: 19% (52 aa)

LVLELCDY-NLYERISLKGV-----------------LGEHEAA-----KIIAPLAKTLGQVHEEG-FIHCDVKPENVLLADRESNHDCCVPKLCDFGLA
.|.|.|.. .| . |. ..                  . | .|.     ...| . . | . |... .|| | ||||.|. .  .      .|..|||..
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK---NYYIKIIDFGIS

C---------------------CMTNPWRVSGIGTWVYM----APEAMLGDGCYTP---AVDVWGLGMVLYHCLTARTPFL-------------------
                      .|..    . .||  ||    ||| . | . ...   ..|.|.||..|| .|. . ||                    
KKYQQNNNCDTNQQQKMQIWKQQMMW----TFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAY

--KLRREE-TRRISESVISSGSGVHHGVFCWDGISDGARDLIR----GMTANRLV----IKEILNHEWI
   |...   . |. .  . ..         ...|. | |.|.     |  ...     ...|||| |.
RKQLYQNIKQKNIQFPKFPWQQ-------IPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase CAMK1c-S2_a.AA TKL 136-224 22 3.8e-20 69.25 In-house 149-289 (364) Show / Hide
Range on Protein: 136-224
Range on HMM: 149-289/364
Sequence Identity: 22% (32 aa)

HEEG--------FIHCDVKPENVLLADRESNH--------DCCVPKLCDFGLACCMT-----NPW----------------RVSGIGTWVYMAPEAMLGD
| ..         ||.| |..|.|. .   |.        . ...|.|||||. .|.     | .                . . .||  .||||.. |.
HSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQ

---------------GCYTPAVDVWGLGMVLYHCLTARTPF
               . |....||.  |.||. .|| ..|.
MNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPY

Kinase CAMK1c-S2_a.AA DCAMKL 97-215 36 4.4e-20 58.67 In-house 92-210 (279) Show / Hide
Range on Protein: 97-215
Range on HMM: 92-210/279
Sequence Identity: 36% (45 aa)

LVLELCDY-NLYERISLKGVLGEHEAAKIIAPLAKTLGQVHEEGFIHCDVKPENVLLADRESNHDCCVPKLCDFGLACCMTN---PWRVSGI-GTWVYMA
||.|.  .  |.. |.  .   | .|| ..  |.| |   || . .| |.|||| |. . |.     . ||||||||| ..    |   . . ||  | |
LVMEYVQGGDLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDG-EKSL-KLCDFGLACHVNGDFGP--LYTVCGTPTYVA

PEAMLGDGCYTPAVDVWGLGMVLY
|| .   | |   ||.| .| .||
PEILMETG-YGCKVDIWAAGVILY

Kinase CAMK1c-S2_a.AA DCAMKL 253-283 40 9e-08 19.68 In-house 245-279 (279) Show / Hide
Range on Protein: 253-283
Range on HMM: 245-279/279
Sequence Identity: 40% (14 aa)

WDGISDGARDLIRGM----TANRLVIKEILNHEWI
||.|||.|.|||. |       |   ..|. | |.
WDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV

TyrKc CAMK1c-S2_a.AA TyrKc 33-283 16 3e-06 -120.8 SMART 1-280 (280) Show / Hide
Range on Protein: 33-283
Range on HMM: 1-280/280
Sequence Identity: 16% (51 aa)

EDNRIRIGGQA--SVFK-VLRRKDGQAFAVKTILDSGDGYFDREDRTLATL-----------GYSNTD--RLPDRK---QVRDLVLELCDY-NLYERI-S
      .|  |   |.| ...    .  |||.. ..    | || | .  |           |.  ..  .        .   .|.|.... .| ... .
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN----FMYIEPLMIVMEYMPHGDLKDYLRK

LKGVLGEHEAAKIIAPLAKTLGQVHEEGFIHCDVKPENVLLADRESNHDCCVPKLCDFGLACCMTNP---------WRVSG-IGTW--V---YMAPEAML
 .. |   .  ..    |.     |. ..|| |    |.|....       . | .||||.   ..           |...  |.   .    ||||.. 
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-

GDGCYTPAVDVWG----------LGMVLYHC-----LTARTPFLKLRREETRRISESV--ISSGSGVHHGVFCWDGISDGARDLIRGMTANRLVIKEILN
 .|..|.. |||           .|.  |       ....  . .... . ... ...  .|.       | | | . .  ..  .   ..|   .||  
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF-------VCCPDEMYQIMKQCWHEDPEDRPTFSEI--

HEWI
|| .
HECF

Kinase CAMK1c-S2_a.AA CAMKL 253-283 40 3.2e-05 12.43 In-house 264-297 (297) Show / Hide
Range on Protein: 253-283
Range on HMM: 264-297/297
Sequence Identity: 40% (14 aa)

WDGISDGARDLIRGM----TANRLVIKEILNHEWI
|  .|  .|||||.|       |  |..|.||.| 
WYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM

Kinase CAMK1c-S2_a.AA MSK 253-283 31 0.000428 9.73 In-house 243-277 (277) Show / Hide
Range on Protein: 253-283
Range on HMM: 243-277/277
Sequence Identity: 31% (11 aa)

WDGISDGARDLIRGM----TANRLVIKEILNHEWI
| ..|  |.|||...     . ||   ... |||.
WQNMSPDAKDLIQWLLTKDPKKRLGMNDLRAHEWK

Kinase CAMK1c-S2_a.AA CAMK 36-62 15 0.061567 1.22 In-house 1-39 (425) Show / Hide
Range on Protein: 36-62
Range on HMM: 1-39/425
Sequence Identity: 15% (6 aa)

RIRIGGQASVFKVLRRKDG------------QAFAVKTI
 .  |. . |... .....            | .|.| |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKII

Kinase CAMK1c-S2_a.AA Ciliate-E2-Unclassified 40-65 30 0.06631 2.42 In-house 10-35 (352) Show / Hide
Range on Protein: 40-65
Range on HMM: 10-35/352
Sequence Identity: 30% (8 aa)

GGQASVFKVLRRKDGQAFAVKTILDS
||...|.|. ..|..|..| |.. ..
GGFGKVYKCQHKKQKQYYAMKYMKKI

Kinase CAMK1c-S2_a.AA DCAMKL 43-60 31 0.076201 0.9 In-house 13-31 (279) Show / Hide
Range on Protein: 43-60
Range on HMM: 13-31/279
Sequence Identity: 31% (6 aa)

ASVFKVLRRKDG-QAFAVK
|.|... .|..| ...| |
AVVHECRHRETGDHKYAMK

Kinase CAMK1c-S2_a.AA CMGC 269-283 20 0.088938 0.57 In-house 499-513 (513) Show / Hide
Range on Protein: 269-283
Range on HMM: 499-513/513
Sequence Identity: 20% (3 aa)

ANRLVIKEILNHEWI
..|. ....|.|...
DKRITAEQALQHPYF

Kinase CAMK1c-S2_a.AA Pkinase 40-62 34 7.099693 0.64 Pfam 10-32 (293) Show / Hide
Range on Protein: 40-62
Range on HMM: 10-32/293
Sequence Identity: 34% (8 aa)

GGQASVFKVLRRKDGQAFAVKTI
|. ..|.|  ....|. .|||.|
GSFGCVYKCHHKGTGKIVAVKII