Gene CAMK1c-S5_h (S.moellendorffii)
CAMK1c-S5_h
Species: S.moellendorffii
Alias: CAMK1c-S5_h
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| CAMK1c-S5_h.AA | Protein | None | 398 | None | Fasta, JSON |
| CAMK1c-S5_h.NA | RNA | None | 1197 | None | Fasta, JSON |
| CAMK1c-S5_h.kin_dom | Protein Kinase Domain | None | 135 | None | Fasta, JSON |
Protein domains of CAMK1c-S5_h.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | CAMK1c-S5_h.AA | MSK | 264-349 | 40 | 1.4e-21 | 69.76 | In-house | 117-206 (277) | Show / Hide |
Range on Protein: 264-349 Range on HMM: 117-206/277 Sequence Identity: 40% (38 aa) MHSRGVVHSDLKPYNIFERLNASAVD--EVMIGDFGMA----TDKQWDMQQYCGTAKYMAPEVVAVKSDGAS-YTAAMDVWGLGVIAYELLRG ||..|..| |||| || | .. | .| . ||| | .|..| |. .|.| |||||.... . . | .| |.|.|||| |..| | MHQKGIIHRDLKPENI---LFDDEEDNGHVKLIDFGFARLFPQDEEWRMKSPCFTLHYMAPEMLRRGYAQDGGYDEACDWWSLGVILYTMLTG |
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| Kinase | CAMK1c-S5_h.AA | AGC | 291-350 | 19 | 2e-21 | 50.75 | In-house | 194-302 (395) | Show / Hide |
Range on Protein: 291-350 Range on HMM: 194-302/395 Sequence Identity: 19% (23 aa) VMIGDFGMATDKQWD-----------------------------------------------------MQQYCG--TAKYMAPEVVAVKSDGASYTAAMD ... |||... | . || |. |||||.. |. | | IKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL--------YGKACD VWG--LGVIAYELLRGY |. ||.. ||.| || WWSFGLGCLMYEMLTGY |
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| Kinase | CAMK1c-S5_h.AA | Pkinase | 264-350 | 38 | 5.5e-21 | 75.29 | Pfam | 124-209 (293) | Show / Hide |
Range on Protein: 264-350 Range on HMM: 124-209/293 Sequence Identity: 38% (36 aa) MHSRGVVHSDLKPYNIFERLNASAVDE---VMIGDFGMA----TDKQWDMQQYCGTAKYMAPEVVAVKSDGASYTAAMDVWGLGVIAYELLRGY .||.|..| |||| ||. .. . . | |.||| | . .. |. .||| ||||||. .| |. . |.|..|.| ||.| |. CHSMGIIHRDLKPENIL--ID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR---GGQYYGPKVDMWSCGCILYEMLCGR |
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| Kinase | CAMK1c-S5_h.AA | Ciliate-E2a | 264-351 | 39 | 5.3e-20 | 55.59 | In-house | 118-214 (275) | Show / Hide |
Range on Protein: 264-351 Range on HMM: 118-214/275 Sequence Identity: 39% (38 aa) MHSRGVVHSDLKPYNIFER-LNASAV--DEVMIGDFGMATDKQWD----MQQYCGTAKYMAPEVVAVKSD--GASYTAAMDVWGLGVIAYELLRGYQ ||.|...| |||| ||. . .... ...| |||.||. . | | | |||. |.|||| . | . . .|. |.| .||| | || |.. MHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDMWSCGVIFYILLCGKP |
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| Kinase | CAMK1c-S5_h.AA | Ciliate-E2 | 252-350 | 22 | 4.5e-19 | 62.11 | In-house | 147-293 (365) | Show / Hide |
Range on Protein: 252-350
Range on HMM: 147-293/365
Sequence Identity: 22% (36 aa)
MKQLFQQRHS-----------------SEMHSRG-VVHSDLKPYNIFERLNASAVDEVMIGDFGMATDKQ-------------WDMQQY-----------
.|....| . ..||.. ..| |.|| ||. . | |||.... . | |.
IKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMD
-----------CGTAKYMAPEVVAVKS-----DGASYTAAMDVWGLGVIAYELLRGY
|||. |||||.. |. .. |. . |.| |||| ||.| |.
QIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK
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| Kinase | CAMK1c-S5_h.AA | CAMK1 | 264-351 | 41 | 2.6e-18 | 49.77 | In-house | 124-214 (276) | Show / Hide |
Range on Protein: 264-351 Range on HMM: 124-214/276 Sequence Identity: 41% (39 aa) MHSRGVVHSDLKPYNIFERLNASAVDE--VM--IGDFGMA--TDKQWD-MQQYCGTAKYMAPEVVAVKSDGASYTAAMDVWGLGVIAYELLRGYQ |||.|.|| |||| |. | .. .. .. | ||| . .| . . |.. ||| |.||||.. |. | | |.|. ||| | || ||. MHSKGIVHRDLKPENL---LYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKK-DKPYDKACDMWSIGVITYILLCGYP |
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| Kinase | CAMK1c-S5_h.AA | RSK | 264-350 | 33 | 3.2e-18 | 63.48 | In-house | 120-209 (278) | Show / Hide |
Range on Protein: 264-350 Range on HMM: 120-209/278 Sequence Identity: 33% (31 aa) MHSRGVVHSDLKPYNIFERLNASAVDEVMIGDFGMATDKQWDMQQ----YCGTAKYMAPEVVAVKSDGAS-YTAAMDVWGLGVIAYELLRGY .|..|..| |||| || .... ||| . . |. | .|.|. |||||.... . . ...| |.| |||. ||.| |. LHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRAN-QQGGHDKACDWWSLGVLMYEMLTGC |
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| Kinase | CAMK1c-S5_h.AA | CAMK | 264-350 | 27 | 2.7e-17 | 51.61 | In-house | 195-331 (425) | Show / Hide |
Range on Protein: 264-350 Range on HMM: 195-331/425 Sequence Identity: 27% (38 aa) MHSRGVVHSDLKPYNIFERLNASAVD-------------EVMIGDFGMATDKQW--------------------------DMQQYCGTAKYMA-PEVVAV .||...|| |||| || | . | . | |||.|. .. |. .||| ||| |||. CHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNG KSDGAS----------YTAAMDVWGLGVIAYELLRGY |. ... |. . |.| .||| | .| || KGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGY |
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| Kinase | CAMK1c-S5_h.AA | CAMK-Unique | 264-350 | 28 | 8.7e-16 | 48.4 | In-house | 173-290 (363) | Show / Hide |
Range on Protein: 264-350 Range on HMM: 173-290/363 Sequence Identity: 28% (34 aa) MHSRGVVHSDLKPYNIFERLNASA------------VDEVMIGDFGMATDKQ---WD--MQQYCGTAKYMAP--------------EVVAVKSDGASYTA ||| ..|| |||. || . . . . |||...... . || .||| |||| ||.. . MHSQDIVHRDLKLENIMVCYSFKDNNHHRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSP AMDVWGLGVIAYELLRGY | | | ||||.|..| |. ASDIWSLGVIMYYMLCGC |
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| Kinase | CAMK1c-S5_h.AA | MAPKAPK | 264-350 | 35 | 4.5e-14 | 39.53 | In-house | 119-215 (292) | Show / Hide |
Range on Protein: 264-350 Range on HMM: 119-215/292 Sequence Identity: 35% (35 aa) MHSRGVVHSDLKPYNI-FERLNASAVDEVMIGDFGMATD-------KQW----DMQQYCGTAKYMAPEVVAVKSDGASYTAAMDVWGLGVIAYELLRGY .||.. | |||| || .. | .. | ..||| | . ... |.|. ||||||| . .. | | | |||| | .| || LHSMNIAHRDLKPENILCTDTNHNCP--VKLCDFGFAKEIHLNHDCTTPITTPELMTPCYTPYYMAPEVVGAFKEAHTYDKSCDMWSLGVIMYIMLCGY |
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| Kinase | CAMK1c-S5_h.AA | ULK | 263-347 | 28 | 4.5e-13 | 42.05 | In-house | 145-250 (329) | Show / Hide |
Range on Protein: 263-347 Range on HMM: 145-250/329 Sequence Identity: 28% (31 aa) EMHSRGVVHSDLKPYNIF-ERLNASAVDEVM--------IGDFGMATDKQWD------MQQYC------GTAKYMAPEVVAVKSDGASYT-AAMDVWGLG |.|.....| |.|| || ... |. |.||| | . | |. . || ||||... . . |. . |.| || ELHKHNIIHRDIKPQNILIHNGQPKT-DSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLG VIAYELL .| ||.| CIFYEML |
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| S_TKc | CAMK1c-S5_h.AA | S_TKc | 74-398 | 17 | 1.9e-12 | 5.49 | SMART | 1-229 (231) | Show / Hide |
Range on Protein: 74-398
Range on HMM: 1-229/231
Sequence Identity: 17% (61 aa)
WELLQ-----------KARQRNSQGPRVWNSKGPLQQKTGKMAEQTPGRGTETTNKEQNAKNHSKTSTTSSTRALVSAQRQEEPPPPIRNAVRPRSDIGR
.|.|. |.| .. .. |.
YEILRKIGKGAFGKVYKCRHKK-----------TGRIVAIKIIK--------------------------------------------------------
MSPTTNEEETRGVAMLVDTRDENAELTETNNRELRVLQCSAAIIIGVLRDGVKGLQGCLEGRKAGYSCILDRNNE--GNLVQSLSCGVL----LSMKQLF
|. ||...|. . . | .. . . ... . |.| . . .
---------------------------EHIRREIQILKK--------HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H
QQRHSSE-------MHSRGVVHSDLKPYNIFERLNASAVDEVMIGDFGMATDKQWDMQQYCGTAKYMAPEVVAVKSDGASYTA-AMDVWGLGVIAYELLR
.. . .||.|..| |||| ||. |. ...|.|||.|. .||| ||||||. .|. . |.| .|.| ||.|
ARFYMYQICCALEYCHSHGIIHRDLKPENIL--LDE----HIKICDFGLARQL----TTFCGTPWYMAPEVL-------GYGKCKCDWWSCGCILYEMLC
GYQSRVEFDFLRARAFLIGFASCEAKDLIQGMLVVEQSKRVSLDAVLA-------HP
|| . . .|| | ||||.|...|... .|| . .|. ||
GYPPFP---QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHP
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| Kinase | CAMK1c-S5_h.AA | CAMK | 368-398 | 48 | 3.6e-09 | 24.96 | In-house | 393-423 (425) | Show / Hide |
Range on Protein: 368-398 Range on HMM: 393-423/425 Sequence Identity: 48% (15 aa) FASCEAKDLIQGMLVVEQSKRVSLDAVLAHP | | |.||||..||.|. .|| ... .|.|| FVSQECKDLIRKMLQVDPEKRMTIEQCLNHP |
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| Kinase | CAMK1c-S5_h.AA | MAPKAPK | 370-398 | 41 | 6.3e-07 | 17.0 | In-house | 262-290 (292) | Show / Hide |
Range on Protein: 370-398 Range on HMM: 262-290/292 Sequence Identity: 41% (12 aa) SCEAKDLIQGMLVVEQSKRVSLDAVLAHP |.|||||| .|... ..| . .|..|| SEEAKDLIRKLLRRDPTQRLTIEQVMNHP |
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| Kinase | CAMK1c-S5_h.AA | ULK | 372-398 | 40 | 2e-06 | 18.45 | In-house | 301-327 (329) | Show / Hide |
Range on Protein: 372-398 Range on HMM: 301-327/329 Sequence Identity: 40% (11 aa) EAKDLIQGMLVVEQSKRVSLDAVLAHP | ||||..||......| | . ...|| ECKDLIRRMLQYDEKDRISWEELFNHP |
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| Kinase | CAMK1c-S5_h.AA | AGC | 372-398 | 29 | 9e-06 | 9.39 | In-house | 357-393 (395) | Show / Hide |
Range on Protein: 372-398 Range on HMM: 357-393/395 Sequence Identity: 29% (11 aa) EAKDLIQGMLVVEQSKRVS----------LDAVLAHP ||||||...|... .|| . . .|| EAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHP |
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| Kinase | CAMK1c-S5_h.AA | Ciliate-E2 | 372-398 | 37 | 2.7e-05 | 14.11 | In-house | 332-363 (365) | Show / Hide |
Range on Protein: 372-398 Range on HMM: 332-363/365 Sequence Identity: 37% (12 aa) EAKDLIQG----MLVVEQSKRVS-LDAVLAHP |.||||. ||.....|| . . .| || ECKDLIKKFGKRMLQKDPEKRITGWEQILNHP |
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| Kinase | CAMK1c-S5_h.AA | CAMK1 | 372-398 | 48 | 4.3e-05 | 10.69 | In-house | 248-274 (276) | Show / Hide |
Range on Protein: 372-398 Range on HMM: 248-274/276 Sequence Identity: 48% (13 aa) EAKDLIQGMLVVEQSKRVSLDAVLAHP ||||.| .||.|. .|| . . .|.|| EAKDFIKHMLEVDPKKRYTCEQCLNHP |
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| Kinase | CAMK1c-S5_h.AA | RSK | 368-398 | 36 | 6.6e-05 | 14.29 | In-house | 241-276 (278) | Show / Hide |
Range on Protein: 368-398 Range on HMM: 241-276/278 Sequence Identity: 36% (13 aa) FASCEAKDLIQGMLVVEQSKRVS-----LDAVLAHP . | ||||||..|| .. .|| . .. ...|| YLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHP |
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| Kinase | CAMK1c-S5_h.AA | MSK | 369-397 | 41 | 0.000998 | 8.47 | In-house | 246-274 (277) | Show / Hide |
Range on Protein: 369-397 Range on HMM: 246-274/277 Sequence Identity: 41% (12 aa) ASCEAKDLIQGMLVVEQSKRVSLDAVLAH .| .||||||..| . .|| ... .|| MSPDAKDLIQWLLTKDPKKRLGMNDLRAH |
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| Kinase | CAMK1c-S5_h.AA | CAMK-Unique | 370-398 | 34 | 0.001118 | 7.79 | In-house | 333-361 (363) | Show / Hide |
Range on Protein: 370-398 Range on HMM: 333-361/363 Sequence Identity: 34% (10 aa) SCEAKDLIQGMLVVEQSKRVSLDAVLAHP | ||||.... ..|....|.|. | |. SQEAKDFVKCCMTVDPDHRWSAKELLEHQ |
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| Kinase | CAMK1c-S5_h.AA | Ciliate-E2a | 372-398 | 40 | 0.006699 | 4.4 | In-house | 247-273 (275) | Show / Hide |
Range on Protein: 372-398 Range on HMM: 247-273/275 Sequence Identity: 40% (11 aa) EAKDLIQGMLVVEQSKRVSLDAVLAHP |.|||...||.. .|| . | || ECKDLMKKMLEKDPKKRITAQQALNHP |
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| Kinase | CAMK1c-S5_h.AA | AGC | 264-279 | 55 | 0.024267 | 0.26 | In-house | 169-186 (395) | Show / Hide |
Range on Protein: 264-279 Range on HMM: 169-186/395 Sequence Identity: 55% (10 aa) MHS-RGVVHSD-LKPYNI .|| .|..| | ||| || LHSHMGIIHRDYLKPENI |
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| Kinase | CAMK1c-S5_h.AA | Pkinase | 372-398 | 37 | 0.045361 | 8.4 | Pfam | 265-291 (293) | Show / Hide |
Range on Protein: 372-398 Range on HMM: 265-291/293 Sequence Identity: 37% (10 aa) EAKDLIQGMLVVEQSKRVSLDAVLAHP |.||.| ..| . .|| . . .| || ECKDFIKWCLCKDPKKRPTAEQILQHP |
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