Gene CAMK1c-S3_e (S.moellendorffii)

CAMK1c-S3_e

Species: S.moellendorffii
Alias: CAMK1c-S3_e
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK1
Subfamily: CAMK1c

Sequence

Name Sequence Type Origin Length Description Download
CAMK1c-S3_e.AA Protein None 572 None Fasta, JSON
CAMK1c-S3_e.NA RNA None 1719 None Fasta, JSON
CAMK1c-S3_e.kin_dom Protein Kinase Domain None 257 None Fasta, JSON

Protein domain

Protein domains of CAMK1c-S3_e.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc CAMK1c-S3_e.AA S_TKc 154-410 27 4.8e-64 220.0 SMART 1-231 (231) Show / Hide 
Range on Protein: 154-410
Range on HMM: 1-231/231
Sequence Identity: 27% (75 aa)

YDVGFELGKGGQGTVHLVSFRMGGKLLAAKSFERSGEREKEIMLKLNGCHGTLEIYDMVEEERKGRWWGSLILELCSC---TLRDRLKMVGR------LA
|... ..|||. |.|...  .  |.. | |   .. .|| .|. |  ..     .||. ..   .. .  ...|.|.    .|.|..|  ||      . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKK--HHPNIVKLYDVFQD---DHLY--MVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

DDEAAFVTKSLAETLREMHNLGVVHRDMKLENVLLTHPAQPYEVKLSDFGVATDRADEMHHLCGTPGYMSPDVLRAGEGGWPKYYTQ-AVDVWGLGLILY
  .|.|... ... |  .|..|..||| | ||.||..     ..|..|||.|.      ...|||| ||.| ||          |.  ..|.| .| |||
E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL----TTFCGTPWYMAPEVL---------GYGKCKCDWWSCGCILY

ELVSGRVAFPEYHSDYVELLLKSVDNVEFALDWSDLSSEAKDLIMGMLEVYPSRRLTVEQVLG-------HPWI
|...|.  ||    .. ... | .            |.||||.|...|.. |..|.|. ..|        |||.
EMLCGYPPFP----QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CAMK1c-S3_e.AA CAMK 159-410 19 1.6e-62 200.03 In-house 1-425 (425) Show / Hide 
Range on Protein: 159-410
Range on HMM: 1-425/425
Sequence Identity: 19% (84 aa)

ELGKGGQGTVHLVSFRMGG------------KLLAAKSFERSG-----------------------------------EREKEIMLKLNG------CHGT
.||.|. |.|.|.  .  .            .  |.|  ...                                    .|| ||| ||.|          
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LEIYDMVEEERKGRWW----------------GSLIL---ELCSCT-----LRDRLKMV---------------GRLADDEAAFVTKSLAETLREMHNLG
. .|.. | ....                     ...   |.||       | |...                 ||.  .||... . ... .. .|...
IKLYEVYEDPHYFK-NTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VVHRDMKLENVLLTHPA--QP------------YEVKLSDFGVATDRAD--------------------------EMHHLCGTPGYMS-PDVLRA-GEGG
.|||| |.||.||..    ..            . .|..||| |.   .                           |.  ||||.||. | ||.  | . 
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

W-------PKYYTQAVDVWGLGLILYELVSGRVAFPEYHSD----------YVELLLKSVDNVEFALD---------------WSDLSSE--------AK
.        .||....|.| .| ||| ...|.  | . . .            . |.. . . ..  .               |.| | |        .|
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLIMGMLEVYPSRRLTVEQVLGHPWI
||| .||.| |..|.|.||.| |||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Pkinase CAMK1c-S3_e.AA Pkinase 154-410 27 5.4e-52 183.85 Pfam 1-293 (293) Show / Hide 
Range on Protein: 154-410
Range on HMM: 1-293/293
Sequence Identity: 27% (84 aa)

YDVGFELGKGGQGTVHLVSFRMGGKLLAAKSFERSGEREKE-----------IMLKLNGCHGTLEIYDMVEEERKGRWWGSLILELCSC-----TLRDRL
| .|  .|.|. |.| .   .  ||. | | .....|....           ||..|| ..  ...||..|.  |.. .  ...|.| .      | |..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNI-VRLYDWFED--KDHIY--MVMEYCEGGLYVMDLFDYI

K--MVGRL--ADDEAAFVTKSLAETLREMHNLGVVHRDMKLENVLLTHPAQP-YEVKLSDFGVA----TDRADEMHHLCGTPGYMSPDVLRAGEGGWPKY
.  . |..   ..|. |. . ... |  .|. |..|||.|.||.|. .  ..   ||..|||.|    . .   |...||||.||.| |.|       .|
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-----GGQY

YTQAVDVWGLGLILYELVSGRVAFP------EYHSDYVELLLKSVDNVEFALDWSDL------------------SSEAKDLIMGMLEVYPSRRLTVEQV
|...||.|..|.||||...||  ||      . |.... . ..    ..|  .|..                   |.|.||.| ..|.. |..|.| ||.
YGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI

LGHPWI
| |||.
LQHPWF
Kinase CAMK1c-S3_e.AA AGC 262-410 20 1.9e-46 116.94 In-house 169-395 (395) Show / Hide 
Range on Protein: 262-410
Range on HMM: 169-395/395
Sequence Identity: 20% (50 aa)

MHN-LGVVHRD-MKLENVLLTHPAQPYEVKLSDFGVATD-----------------------------------------------------RADEMHHL
.|. .|..||| .|.||.||..      .||.||| ..                                                        |  . .
LHSHMGIIHRDYLKPENILLDED---GHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTF

CG--TPGYMSPDVLRAGEGGWPKYYTQAVDVWG--LGLILYELVSGRVAFPEYHSD-------YVELLLKSVD------NVEFALDW---------SDLS
||  || ||.| .|          |..|.| |.  || ..||...|.  |     .         . . ...       | .  ...         . .|
CGPCTPEYMAPEIL----------YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFS

SEAKDLIMGMLEVYPSRRLT----------VEQVLGHPWI
.|||||| ..|.. |..||.          .|..  ||| 
PEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase CAMK1c-S3_e.AA Ciliate-E2 224-410 22 2.7e-44 149.97 In-house 111-365 (365) Show / Hide 
Range on Protein: 224-410
Range on HMM: 111-365/365
Sequence Identity: 22% (62 aa)

LILELCSC-TLRDRLK------------MVGRLADDEAAFVTKSLAE---------------TLREMHNLG-VVHRDMKLENVLLTHPAQPYEVKLSDFG
|..|.|.  .|.|..|              ... . |.....| ...                |...|. . ..||| |.||.|.        .|..|||
LVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF--------IKIIDFG

VATDRADE----------------------------------MHHLCGTPGYMSPDVLRAGE-----GGWPKYYTQAVDVWGLGLILYELVSGRVAFPEY
 ...  |.                                   . .|||||||.| .|. ..     ..  |.|. ..|.| || ||||...|.  |   
LSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQ--KGYDYKCDIWSLGVILYEMLFGKPPF---

HSDYVELLLKSVDNVEFALD---------------WSDLSSEAKDLIMG----MLEVYPSRRLT-VEQVLGHPWI
      .  .   ...|                  | ..| |.||||      ||.. |. |.|  ||.| |||.
------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase CAMK1c-S3_e.AA CAMKL 224-410 28 4.7e-42 131.9 In-house 98-297 (297) Show / Hide 
Range on Protein: 224-410
Range on HMM: 98-297/297
Sequence Identity: 28% (60 aa)

LILELCSCT---LRDRLKMV----GRLADDEAAFVTKSLAETLREMHNLGVVHRDMKLENVLLTHPA-QPYEVKLSDFGVATD-RA-----DE-MHHLCG
|..|.||     | |...      ||.  .|| .  . . . .  .|..|.|||| |.||.||..   .   .|..||| ..  |      .. ..  ||
LVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN--NIKIIDFGFSNMYRPCIFGPGQKLKTFCG

TPGYMSPDVLRAGEGGWPKYYTQAVDVWGLGLILYELVSGRVAFPEYH------SDYVELLLKSVDNVEFALDWSDLSSEAKDLIMGMLEVYPSRRLTVE
.| ||.| ..  .     .|. ..||.| .| ||| .| |.. | . .      ... .|..|     ..   |...| ...||| .||.| |..| |..
SPPYMAPEIFQGN---NKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIH

QVLGHPWI
|.. ||| 
QIMNHPWM
Kinase CAMK1c-S3_e.AA RSK 235-410 29 5.8e-41 142.4 In-house 90-278 (278) Show / Hide 
Range on Protein: 235-410
Range on HMM: 90-278/278
Sequence Identity: 29% (56 aa)

DRLKMVGR---LADDEAAFVTKSLAETLREMHNLGVVHRDMKLENVLLTH-PAQPYEVKLSDFGVATD-RAD---EMHHLCGTPGYMSPDVLRAGEGGWP
..|.  ..   .  |||.|.   .. ... .| .|..||| |.||.|...   .. ..||.||| .   |.|    ..  |.|  || | .|. ..   .
THLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRAN--QQ

KYYTQAVDVWGLGLILYELVSGRVAFPEYHSD-YVELLLKSVDNVE--FALD-WSDLSSEAKDLIMGMLEVYPSRRLT-----VEQVLGHPWI
. ...|.|.| || ..||. .|.. |     |   . ..| . . .  . .. |. || |||||| .||.. |..||.     .|... |||.
GGHDKACDWWSLGVLMYEMLTGCPPFQG-PNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase CAMK1c-S3_e.AA MSK 236-410 30 1.8e-39 131.06 In-house 91-277 (277) Show / Hide 
Range on Protein: 236-410
Range on HMM: 91-277/277
Sequence Identity: 30% (58 aa)

RLKMVGRLADDEAAFVTKSLAETLREMHNLGVVHRDMKLENVLLTHPAQPYEVKLSDFGVATDRADE----MHHLCGTPGYMSPDVLRA---GEGGWPKY
...  ..   .|....  .|   .. || .|..|||.|.||.|..      .|||.||| |  .  .    |.  |.|  ||.|..||    ..||    
HIRKREHFDESECRMIMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDNGHVKLIDFGFARLFPQDEEWRMKSPCFTLHYMAPEMLRRGYAQDGG----

YTQAVDVWGLGLILYELVSGRVAFPEYHSDYV------ELLLKSVDNVEFALD---WSDLSSEAKDLIMGMLEVYPSRRLTVEQVLGHPWI
| .|.|.|.|| |||.. .|.| |    .|          . | .   || ..   |.  | .||||| ..|.. |..||...  . | |.
YDEACDWWSLGVILYTMLTGQVPFQQNEDDRQHSCNSHHEIMKRICKGEFSFPGMAWQNMSPDAKDLIQWLLTKDPKKRLGMNDLRAHEWK
Kinase CAMK1c-S3_e.AA DCAMKL 235-410 34 3.9e-38 115.85 In-house 104-279 (279) Show / Hide 
Range on Protein: 235-410
Range on HMM: 104-279/279
Sequence Identity: 34% (63 aa)

DRLKMVGRLADDEAAFVTKSLAETLREMHNLGVVHRDMKLENVLLTH-PAQPYEVKLSDFGVATDRAD---EMHHLCGTPGYMSPDVLRAGEGGWPKYYT
| .  ...    .||  .  |.. |. .| ...|||| |.|| |.   .    ..|| ||| |.   .    .   |||| |  | .|.  | |    | 
DAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILM--ETG----YG

QAVDVWGLGLILYELVSGRVAFPEYHSD--YVELLLKSVDNVEFALD---WSDLSSEAKDLIMGMLEVYPSRRLTVEQVLGHPWI
  ||.| .| ||| |  |   ||   |     | | . .   .| ..   |.. |. |||||  ||.| | .| | ||.. |||.
CKVDIWAAGVILYILLCG---FPPFRSPDNDQEELFDQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV
Kinase CAMK1c-S3_e.AA STE 224-410 21 9.6e-33 112.99 In-house 114-359 (359) Show / Hide 
Range on Protein: 224-410
Range on HMM: 114-359/359
Sequence Identity: 21% (54 aa)

LILELCSC-TLRDRLKMV--------------GRLADDEAAFVTKSLAET-LREMHNLGVVHRDMKLENVLLTHPAQPYEVKLSDFGVATDRAD------
...|...  .|.| .| .              .|.  .. |...... .  |   |.....||| |  |.||        |||.||||..  .|      
ICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL--------VKLCDFGVCGQLTDSMANIQ

-------------EMHHLCGTPGYMSPDVLRAGEGGWP-KYYTQAVDVWGLGLILYELVSGRVAFPEYHSDYVELLLKSV---------------DNVEF
             .  ...||| .|.| |.. ...|   | |.  .|.| ||. . |.. |.. . ..|  .. ..                   .   .
SNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-RDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPL

ALDWS----------------DLSSEAKDLIMGMLEVYPSRRLTVEQVLG--HPWI
  . |                 .|.| || |   |.  |. | |..| |   ||.|
PDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase CAMK1c-S3_e.AA Ciliate-E2a 224-353 32 1.5e-28 81.19 In-house 76-217 (275) Show / Hide 
Range on Protein: 224-353
Range on HMM: 76-217/275
Sequence Identity: 32% (47 aa)

LILELCSC-TLRDRLKMVGRLADD--EAAFVTKSLA-ETLREMHNLGVVHRDMKLENVLLT--HPA--QPYEVKLSDFGVATDR--ADE--MHHLCGTPG
|..|.|.  .| |..|  .|.     |.. . . |  . |  ||.....||| |.||.|..   .   |. ..|..||| ||.    ..  |.  |||||
LVMEYCEGGELYDKIKQCKRFFEEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPG

YMSPDVLRAGE--GGWPKYYTQAVDVWGLGLILYELVSGRVAFP
|. | ||   |   .  | |.. .|.| .|.|.| |..|.  |.
YVAPEVLNNKEVLKH--KQYDTKCDMWSCGVIFYILLCGKPPFK
Kinase CAMK1c-S3_e.AA CAMK1 262-343 39 8.6e-25 68.95 In-house 124-207 (276) Show / Hide 
Range on Protein: 262-343
Range on HMM: 124-207/276
Sequence Identity: 39% (34 aa)

MHNLGVVHRDMKLENVLLTHPAQPYEVK--LSDFGVATDRA-D--EMHHLCGTPGYMSPDVLRAGEGGWPKYYTQAVDVWGLGLILY
|| .|.|||| | || |.  .    ..|  ..||| ..    |   |   ||||||. |.||   .   .| | .|.|.|. | |.|
MHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKK---DKPYDKACDMWSIGVITY
Kinase CAMK1c-S3_e.AA CAMK1 376-410 55 2.6e-17 46.83 In-house 241-276 (276) Show / Hide 
Range on Protein: 376-410
Range on HMM: 241-276/276
Sequence Identity: 55% (20 aa)

WSDLSSE-AKDLIMGMLEVYPSRRLTVEQVLGHPWI
| . |.. |||.| .|||| |. |.|.||.| ||||
WDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase CAMK1c-S3_e.AA Ciliate-E2a 375-410 45 4.3e-14 37.89 In-house 239-275 (275) Show / Hide 
Range on Protein: 375-410
Range on HMM: 239-275/275
Sequence Identity: 45% (17 aa)

D-WSDLSSEAKDLIMGMLEVYPSRRLTVEQVLGHPWI
. |...|.|.|||. .|||..|. |.| .| | ||| 
ECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase CAMK1c-S3_e.AA TyrKc 154-410 17 5.4e-05 -141.88 SMART 1-280 (280) Show / Hide 
Range on Protein: 154-410
Range on HMM: 1-280/280
Sequence Identity: 17% (52 aa)

YDVGFELGKGGQGTVHLVSFRMGGKLLAAKSFERSG----EREKEIMLKL-NGCHGTLEIYDMVEEER------KGRWWGSLILELCSC-TLRDRLKMVG
   | .|| |  |.|..   .      | |.   .      || .|| ||       . .|  . ..       .  .   ...|...   |.|.|.  .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLM---IVMEYMPHGDLKDYLRKHR

R-LADDEAAFVTKSLAETLREMHNLGVVHRDMKLENVLLTHPAQPYEVKLSDFGVATDRADE--------MHHLC---GTPG-----YMSPDVLRAGEGG
. |  ..        |.  .  |  ...|||    |.|....     || |||| . |  |.        . .     |. .      |.| ... |.  
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK--

WPKYYTQAVDVWGLGLILYELVSGRVAFPEYHS-----DYVELLLKSVDNVEFALDWSD--------LSSEAKDLIMGMLEVYPSRRLTVEQVLGHPWI
    .| . |||  |  ..|. .     . |          . ... |.. .      .         ..|  ...    .  |. | | ...  |  .
----FTTKSDVWSFGVCMWEIFTY--GQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase CAMK1c-S3_e.AA CAMKL 154-170 52 0.001067 7.51 In-house 1-17 (297) Show / Hide 
Range on Protein: 154-170
Range on HMM: 1-17/297
Sequence Identity: 52% (9 aa)

YDVGFELGKGGQGTVHL
|..| .||||. |.| |
YRIGKTLGKGSFGKVKL
Kinase CAMK1c-S3_e.AA Ciliate-E2 154-172 26 0.006192 5.89 In-house 1-19 (365) Show / Hide 
Range on Protein: 154-172
Range on HMM: 1-19/365
Sequence Identity: 26% (5 aa)

YDVGFELGKGGQGTVHLVS
|..   .|.|..|.| ...
YKFIKKIGQGNFGSVYKCK