Gene CDC2-S1_a (S.moellendorffii)

CDC2-S1_a

Species: S.moellendorffii
Alias: CDC2-S1_a
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDC2-smoe1

Sequence

Name Sequence Type Origin Length Description Download
CDC2-S1_a.AA Protein None 312 None Fasta, JSON
CDC2-S1_a.NA RNA None 939 None Fasta, JSON
CDC2-S1_a.kin_dom Protein Kinase Domain None 244 None Fasta, JSON

Protein domain

Protein domains of CDC2-S1_a.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc CDC2-S1_a.AA S_TKc 8-276 25 8.1e-39 136.19 SMART 1-231 (231) Show / Hide 
Range on Protein: 8-276
Range on HMM: 1-231/231
Sequence Identity: 25% (72 aa)

SFREERVPRYGYGGIDRGIPRVGYNGSNEKVVIKSMNQDPRVFDMDRIEEEFDLMIECEHKNVLKALDVGTDEHYYTYMVLEYIDC---DLMDFFGQDKV
    . . . ..|   ... .     ....| || ..        ..|. | ... .  |.|. | .||  |   . |||.||.|    ||.|.  . . 
YEILRKIGKGAFGKVYKCRHKK----TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGR

--YYSISKADKIREILRQILLGLACMHGRGVAH-----QNVGYYSLLVKRNYNEFVVKLADFSCARRITTPANPEIAGSPEYSAPEVLRMEAERMGA-KA
  ...      .| ...||...|. .| .|. |     .|.    || .      ..|..||  ||..       . |.|.| |||||       |  |.
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENI----LLDE------HIKICDFGLARQL-----TTFCGTPWYMAPEVL-----GYGKCKC

DIWSAGVVFLQMLMGYNPFYPGISHQQEREKVVGEIHRFLDEDMFKLIEDKAAVELLKGMLAWDPEKRFTAQEALD-------SPYL
|.|| |...  || || ||.    ..|.  |..|               .. | ......| .||||| || |||         |..
DWWSCGCILYEMLCGYPPFP----QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CDC2-S1_a.AA Ciliate-E2 67-276 19 2.5e-29 97.83 In-house 91-365 (365) Show / Hide 
Range on Protein: 67-276
Range on HMM: 91-365/365
Sequence Identity: 19% (58 aa)

HKNVLKALDVGTD-EHYYTYMVLEYIDC-DLMD--------FFGQ---DKVYYSISKADKI-REILR-----------QILLGLACMHGRG-VAHQNVGY
|.|..|  ..  .    . |.|.||..  ||.|        .. .   |  |... .. .| ..||.           .|.|.|  .| .. . | .   
HPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKP

YSLLVKRNYNEFVVKLADFSCARRITTP-------ANPE--------------------------IAGSPEYSAPEVLRMEA-------ERMGAKADIWS
  .|.        .|..||  .......          .                          |.|.|.| |||.|...        .. . |.||||
ENILF--------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWS

AGVVFLQMLMGYNPFYPGISHQQEREKVVGEIHRFLDEDM-----------FKLIEDKAAVELLKG----MLAWDPEKRFT-AQEALDSPYL
.||.. .||.|. ||        ....  ..|  .  |              ..  .. .  |.|     ||  |||||.| ....|. |..
LGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase CDC2-S1_a.AA CAMK 29-276 19 5.7e-28 86.64 In-house 27-425 (425) Show / Hide 
Range on Protein: 29-276
Range on HMM: 27-425/425
Sequence Identity: 19% (78 aa)

VGYNGSNEKVVIKSMNQDP---------------------------RVFDMDRIEEEFDLMIECE-------HKNVLKALDVGTDEHY------------
. |.  ..|| || .. .                            | .|..... | ..|  .        |.|..| ..|  |.||            
I-YTN-GQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYETSKQ

------YTYMVL---EYIDC-----DLMDFFGQDKVYY-----------SISKADKIREILRQILLGLACMHGRGVAHQ-----NVGYYSLLVKRNYNE-
      . |||.   ||..      || |.  . . |.              . .  | . |||. ... .| ....|      |.    ||...| .. 
VFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENI----LLDDNNDDSD

------------FVVKLADFSCARRITTPANPE-------------------------IAGSPEYSA-PEVLRME------------AERMGAKADIWSA
            . .|..||  |....   |                             |.||| | ||||. .             .  | |.|.||.
PVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSC

GVVFLQMLMGYNPFY-PGIS----------HQQEREKVVGEIHRFLDEDMFKL------------IEDK-------AAVELLKGMLAWDPEKRFTAQEAL
||.   || || ||| .  .          ...|  . . .     ....|.             | |         .  |...||  |||||.|....|
GVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCL

DSPYL
. | .
NHPWM
Kinase CDC2-S1_a.AA Pkinase 150-276 23 7.3e-27 96.06 Pfam 143-293 (293) Show / Hide 
Range on Protein: 150-276
Range on HMM: 143-293/293
Sequence Identity: 23% (37 aa)

NEFVV----KLADFSCAR---RITTPANPEIAGSPEYSAPEVLRMEAERMGAKADIWSAGVVFLQMLMGYNPFYPGI----SHQQEREKVVGEIHRFLDE
|. ..    |..|| .|.       . .  ..|.|.| ||||.| ...  | |.|.||.|... .|| |. ||. |     .   ......   .. |..
NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-GGQYYGPKVDMWSCGCILYEMLCGRPPFP-GHCWHDN-HDQMQMICRIMGPPLHF

DMFKLIED------------------KAAVELLKGMLAWDPEKRFTAQEALDSPYL
| .....                   ... ...|..|..||.|| ||...| .|..
DWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase CDC2-S1_a.AA ULK 40-276 19 1.9e-24 83.71 In-house 38-324 (324) Show / Hide 
Range on Protein: 40-276
Range on HMM: 38-324/324
Sequence Identity: 19% (58 aa)

IKSMNQDPRVFD----MDRIEEEFDLMIECE---HKN--VLKALDVGTDEHY-YTYMVLEYIDC-DLMDFFGQDKV-----YYSISKADKIREILRQILL
.|.||...   .    .. .. |  .| .     |.|  . | .|.  . .. ..|...|| .. || ..  ..|      .  .   ........||. 
KKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICN

GLACMHGRGVAH-----QNVGYYSLLVKRNYNEF---------VVKLADFSCARRITTP-ANPEIA----------GSPEYSAPEVLRME--AERMG-AK
|. ..| ... |     ||     .|.. .   .         |.|.|||  |. .  .  .  .           |.| | ||..|  .   .  . .|
GFKELHKHNIIHRDIKPQN-----ILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYK

ADIWSAGVVFLQMLMGYNPFYPGISHQQE--REKVVG-----EIHRFLDEDMFK---LIED--KAAVELLKGMLAWDPEKRFTAQEALDSPYL
.|||| |..| .|| |. ||.     .|.   .| .      .|        |.    .    .   .|...||  |...|.. .| .. | .
CDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase CDC2-S1_a.AA Ciliate-E2-Unclassified 83-276 21 6.7e-24 79.79 In-house 95-352 (352) Show / Hide 
Range on Protein: 83-276
Range on HMM: 95-352/352
Sequence Identity: 21% (56 aa)

YTYMVLEYI-DCDLMDFFGQDKV------------YY-SISKADKIR-----EILRQILLGLACMHGRG-VAHQNVGYYSLLVKRNYNEFVVKLADFSCA
. |.|.||. . ||...  . |             ..  |    ...      ...|||.||  .|  . . | .     .|.. | . . .|..||. .
NIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGIS

RRITTPAN-----------------PEIAGSPEYS----APEVLRM-EAERMGA-KADIWSAGVVFLQMLMGYNPFY---PGI----------------S
... .. |                   ..|.|.|     |||||.  . . . | |.|||| ||.. .||.|| |||     .                 
KKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQL

HQQE-REKVVGEIHRF------LDEDMFKLIEDKAAVELLKGMLAWDPEKRFTAQEALDSPYL
.|.    ..    . .      ...    .|.     .||. || ..|.|| |....|  |..
YQNIKQKNIQFPKFPWQQIPKHWSPEAKDFIN-----DLLQKMLKKNPNKRITFEQILNHPWF
Kinase CDC2-S1_a.AA ULK 34-276 20 2.3e-23 78.47 In-house 27-329 (329) Show / Hide 
Range on Protein: 34-276
Range on HMM: 27-329/329
Sequence Identity: 20% (64 aa)

SNEKVVIKS-----MNQDPRVFD----MDRIEEEFDLMIECE----HKN----VLKALDVGTDEHY-YTYMVLEYIDC-DLMDFFGQDKV------YYSI
.||||..|      |||..   .    .. .. | ..| .      |||    . | .|.  . .. ..|...|| .  ||...  ..|       .  .
VNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKR

SKADKIREILRQILLGLACMHGRGVAH-----QNVGYYSLLVKRN----------YNEFVVKLADFSCARRITTP-----ANPEIA------GSPEYSAP
   ........||| |. ..| ... |     ||.     |.. .          . . |.|.|||  |. .. .      .          |.| | ||
LSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNI-----LIHNGQPKTDSKKVHP-NGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAP

EVLRME--AERMG-AKADIWSAGVVFLQMLMGYNPFYPGISHQQE-----REKVVG-----EIHRFLDEDM---FKLIEDKAAVELLKGMLAWDPEKRFT
..|  .   .  . .|.|||| |..| .|| |. |||     .|      ...  .     .|  .  .      . .  .   .|...||  |...|..
QILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRIS

AQEALDSPYL
 .| .. | .
WEELFNHPWF
Kinase CDC2-S1_a.AA CAMK-Unique 56-276 19 3.9e-19 59.63 In-house 64-363 (363) Show / Hide 
Range on Protein: 56-276
Range on HMM: 64-363/363
Sequence Identity: 19% (58 aa)

EEEFDLMIECEHKNVLKALDV----GTDEHY--------------YTYMVLEYIDCD-LMDFFGQ-DKVY---------------YSISKA--DKIREIL
..| ....   | | .| .|.      |. |              | |.|.||...  | | . . |. |                 .  .    .. | 
KREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLIIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIM

RQILLGLACMHGRGVAHQNVGYYSLLVKRNYN-------------EFVVKLADFSCARRITTPANP----EIAGSPEYSAP--------------EVLRM
...|  .| ||  .. | .     ..|. . .                .||.||  .. . .   .    .. |.|.| ||              ||. |
QCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHHRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINM

EAERMGAKA----DIWSAGVVFLQMLMGYNPFYPGISHQ-------QEREKVVGEIHRF--LDEDMFKL---IEDKAAVELLKGMLAWDPEKRFTAQEAL
   . . .     |||| ||.   || |. ||..  .          ..|.    ....  .|..|. .   | . .|  ..|. .  || .| .| |.|
--QCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDRDYENHDKEIFECIC--KGDYCNFDWKMWHGPDYISQ-EAKDFVKCCMTVDPDHRWSAKELL

DSPYL
.....
EHQWI
Kinase CDC2-S1_a.AA STE 34-276 18 8.1e-19 63.17 In-house 29-359 (359) Show / Hide 
Range on Protein: 34-276
Range on HMM: 29-359/359
Sequence Identity: 18% (63 aa)

SNEK---------VVIKSMN----------------QDPRVFDMDRIEEEFDLMIECE--HKNVLKALDVGTDE------HYYTYMVLEYIDC----DLM
..|.         . || ||                ..    .|..|..| ..| .|   |.|. | ..   .|      . . ....||.|     |..
TGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDII

D-FFGQDKVYYSISK------ADKIREILRQILLG-LACMHGRGVAHQNVGYYSLLVKRNYNEFVVKLADFSCARRITT---------------PANPE-
.  .|  |   . ..       . |. |.|||| | |.  |  .. |  .     |.        |||.|| .. ..|                    . 
KHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL--------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKR

--IAGSPEYSAPEVLRMEAER----MGAKADIWSAGVVFLQMLMGYNPF---YPG-ISHQQEREKVVGE----IHRFLDEDMFKLIED------------
  ..|.| . ||||.. . .      ..|.|||| | . . |. |  |.   .|     .  .......    .   ....  .| ..            
NTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL-CIVNGPPPPLPDHLSQNEMISYGGS

---------KAAVELLKGMLAWDPEKRFTAQEALD--SPYL
         .   . ..  |  ||.|| ||.. |    | .
GTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase CDC2-S1_a.AA CMGC 241-276 47 9.7e-15 43.95 In-house 478-513 (513) Show / Hide 
Range on Protein: 241-276
Range on HMM: 478-513/513
Sequence Identity: 47% (17 aa)

FKLIEDKAAVELLKGMLAWDPEKRFTAQEALDSPYL
... .|. |..|||.|| .||.|| ||..||. ||.
KRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase CDC2-S1_a.AA Ciliate-E2a 246-276 48 2.4e-12 32.7 In-house 245-275 (275) Show / Hide 
Range on Protein: 246-276
Range on HMM: 245-275/275
Sequence Identity: 48% (15 aa)

DKAAVELLKGMLAWDPEKRFTAQEALDSPYL
.|..  |.|.||  ||.||.|||.||..|. 
SKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase CDC2-S1_a.AA CMGC 34-218 16 2.7e-11 32.44 In-house 37-345 (513) Show / Hide 
Range on Protein: 34-218
Range on HMM: 37-345/513
Sequence Identity: 16% (51 aa)

SNEKVVIKSMNQDPRVF-DMD----------RIEEEFDLMIECE-----------------HKNVLKALDVGTDEH----------------YYTYMVLE
.||.| || . ...    ..           |.  |  .. .                   |.|..| .|. ....                .. |.| |
TNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFE

YIDCDLMDFFGQDK--------VYYSISK-----------------ADKIREILRQILLGLA--CMHGRG--VAHQNVGYYSLLVKRNYNE---------
|.|.|| ..  . .        .. |  .                    || . .||| ||.   .| ..  . |       .|.  |            
YMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSE

--------FVVKLADFSCARRITTP-----------------------ANPEIAGSPEYSAPEVLRMEA--------ERMGAKADIWSAGVVFLQMLMGY
        ...|..||  || . ..                       .. .   .  | |||.|               . . |.||.| .|  |..||
DWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGY

-------NPFYPG
        |. ||
QSLIFRGKPLFPG
Kinase CDC2-S1_a.AA CDK 251-276 50 4.8e-11 31.41 In-house 259-284 (284) Show / Hide 
Range on Protein: 251-276
Range on HMM: 259-284/284
Sequence Identity: 50% (13 aa)

ELLKGMLAWDPEKRFTAQEALDSPYL
.|| .||. ||.||..|..||..||.
DLLNKMLCYDPKKRISAEQALQHPYF
Kinase CDC2-S1_a.AA Pkinase 33-135 23 8.2e-11 39.31 Pfam 22-131 (293) Show / Hide 
Range on Protein: 33-135
Range on HMM: 22-131/293
Sequence Identity: 23% (26 aa)

GSNEKVVIKSMNQDPRVFDMDRIEE---EFDLMIECEHKNVLKALDVGTDEHYYTYMVLEYIDCD--LMDFF----GQDKVYYSISKADKIREILRQILL
|....|..| .. . .  ..|..     |  .| .. |.|... .|. .| . . |||.|| ...  .|| |    ....  ..    . .. ...||| 
GTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFY-FSEWECKFYMYQILR

GLACMHGRGVAH
||. .| .|. |
GLEYCHSMGIIH
Kinase CDC2-S1_a.AA CDK 58-135 26 1.4e-09 26.68 In-house 58-131 (284) Show / Hide 
Range on Protein: 58-135
Range on HMM: 58-131/284
Sequence Identity: 26% (23 aa)

EFDLMIECEHKNVLKALDVGTDEH----------YYTYMVLEYIDCDLMDFFGQDKVYYSISKADKIREILRQILLGLACMHGRGVAH
|  |. |. |.|. | .|| ....             ||| ||.| ||. .               |. ...|.| ||. .| ... |
EISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEYMDHDLKKYMD-------------IKCYMWQLLRGLHYCHSNWIMH
Kinase CDC2-S1_a.AA Ciliate-E2a 173-216 39 5.8e-07 16.57 In-house 170-217 (275) Show / Hide 
Range on Protein: 173-216
Range on HMM: 170-217/275
Sequence Identity: 39% (19 aa)

IAGSPEYSAPEVLRMEAE----RMGAKADIWSAGVVFLQMLMGYNPFY
. |.| | ||||| .. .    . . | |.||.||.|  .|.|. ||.
KCGTPGYVAPEVLNNKEVLKHKQYDTKCDMWSCGVIFYILLCGKPPFK
TyrKc CDC2-S1_a.AA TyrKc 19-276 18 1e-06 -115.15 SMART 12-280 (280) Show / Hide 
Range on Protein: 19-276
Range on HMM: 12-280/280
Sequence Identity: 18% (55 aa)

YGGIDRGIPRVGYNGSNEKVVIKSMNQDPRVFDMDRIEEEFDLMIEC--EHKNVLKALDVGTDEH------YYTYMVLEYIDC-DLMDFFGQDKVYYSIS
.| . .|. .       ..| .|... |     .  . .|  .| .   .|.|... . | |..          ..|.|| .  || |.    .    ..
FGEVYKGTWK-------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK--LC

KADKIREILRQILLGLACMHGRGVAH-----QNVGYYSLLVKRNYNEFVVKLADFSCARRITTP-----ANPEIAG----SPE------YSAPEVLRMEA
 .|.. ..  ||  | .  | ... |      |.     ||..|.   .|| .||  .| |.       .   .      .          |||..    
MKDLL-SFCWQIACGMEYLHSKNCIHRDLAARNC-----LVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NY

ERMGAKADIWSAGVVFLQMLMGYNPFYPGISHQQEREKVVGEIHRFLDEDMFKLIEDK--------AAVELLKGML---AWDPEKRFTAQEALDSPYL
 .   | |.|| ||.   ..    . |||.  |    .   |....... .   . .         .  |. . |.   . |||.| | .|     ..
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ---MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase CDC2-S1_a.AA Ciliate-E2a 67-135 34 0.000371 8.16 In-house 58-125 (275) Show / Hide 
Range on Protein: 67-135
Range on HMM: 58-125/275
Sequence Identity: 34% (25 aa)

HKNVLKALDVGTDEHYYTYMVLEYIDC-DLMDFFGQDKVYYSISKA-DKIREILRQIL-LGLACMHGRGVAH
|.|..|  .|  ||..| |.|.||..  .|.| . |.|   .. .   .|..|..|.|  ||. || |.. |
HPNIIKLYEVYEDENNY-YLVMEYCEGGELYDKIKQCK---RFFEEIQEICDIMQQLLWQGLHYMHQRNIMH
Kinase CDC2-S1_a.AA CDK 197-215 31 0.112223 0.95 In-house 204-225 (284) Show / Hide 
Range on Protein: 197-215
Range on HMM: 204-225/284
Sequence Identity: 31% (7 aa)

DIWSAGVVFLQMLM---GYNPF
|.||.| .|  |..   .   |
DMWSVGCIFAEMFTDVTRKPLF