Gene CDC2-S1_e (S.moellendorffii)

CDC2-S1_e

Species: S.moellendorffii
Alias: CDC2-S1_e
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDC2-smoe1

Sequence

Name Sequence Type Origin Length Description Download
CDC2-S1_e.AA Protein None 290 None Fasta, JSON
CDC2-S1_e.NA RNA None 873 None Fasta, JSON
CDC2-S1_e.kin_dom Protein Kinase Domain None 260 None Fasta, JSON

Protein domain

Protein domains of CDC2-S1_e.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase CDC2-S1_e.AA Pkinase 6-265 24 5.4e-62 217.08 Pfam 1-293 (293) Show / Hide 
Range on Protein: 6-265
Range on HMM: 1-293/293
Sequence Identity: 24% (74 aa)

IDYSTRLGRGTGGTVREGINLDTMEKVAIKEMVEHLNLHEETKLV-----YGLLQECQHGNIVKLLDVGSIGGKTYMVFEHMFGDLYKFKKRLGMLM---
.    ..|.|. |.|..... .| ..||.|..  . . ... .         ......| |||.|.|.   ... |||.|.. |.||       ...   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLY-VMDLFDYISTWR

KRTL--NREEIKTIIEQILQALAYMHEHGIVHQDIKTANVLINKEGTK---VKLCDFDHARRV-TTPPRDPETI-GTLAYNAPEIILGDTQELGSGVDVW
....    .|.| .. |||..|.|.|..||.| |.| .|.||...|.    ||.|||  |. . . . . . |. ||. | |||.|. . |. |. ||.|
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-GGQYYGPKVDMW

GAGVILAELVLGYNPFS--VVRESHAARELYRVVEEIKERLHREIG----------------------DEDILELLDNMLVWEPEERWSAERALSSSFF
..|.||.|...|. ||.  .  . . .........  . .||...                       .|. .......| . |..|..|| .| . .|
SCGCILYEMLCGRPPFPGHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
S_TKc CDC2-S1_e.AA S_TKc 6-265 26 2.9e-58 200.82 SMART 1-231 (231) Show / Hide 
Range on Protein: 6-265
Range on HMM: 1-231/231
Sequence Identity: 26% (73 aa)

IDYSTRLGRGTGGTVREGINLDTMEKVAIKEMVEHLNLHEETKLVYGLLQECQHGNIVKLLDVGSIGGKTYMVFEHMFG---DLYKFKKRLGM-LMKRTL
 .    .|.|. |.|. ... .| ..||||..       | ..    .|.. .| |||||.||    .. |||.|.. |   ||... |. |    .. .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

NREEIKTIIEQILQALAYMHEHGIVHQDIKTANVLINKEGTKVKLCDFDHARRVTTPPRDPETIGTLAYNAPEIILGDTQELGS-GVDVWGAGVILAELV
.  ... .. ||..||.|.|.|||.| |.| .|.|...    .|.|||  ||..         .||. | |||..       |   .|.|  |.||.|..
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL-----GYGKCKCDWWSCGCILYEML

LGYNPFSVVRESHAARELYRVVEEIKERLHREIGDEDILELLDNMLVWEPEERWSAERALS-------SSFF
 || ||.         ......            ... .......|...||.|..|  ||          .|
CGYPPFP------QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CDC2-S1_e.AA CAMK 11-265 17 1.1e-46 148.09 In-house 1-425 (425) Show / Hide 
Range on Protein: 11-265
Range on HMM: 1-425/425
Sequence Identity: 17% (76 aa)

RLGRGTGGTVREGINLDTM------------EKVAIKEM------------------VEHL---------NLHEETKLV--YGLLQECQ-------HGNI
 ||||. |.|...|.  |             .||||| .                  ...          . . . ..   . ... .|       | ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKLLDVGS------------IGGK--------TYMVF---EHMFGD------LYKFKKRLG----------MLMKRTLNREEIKTIIEQILQALAYMHEH
.||..|                 |         |||.   |.. |       . . ... .            ... .. .| .... ||..|..|.|.|
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHSH

GIVHQDIKTANVLINKEG----------------TKVKLCDFDHARRVTTPPRDP------------------------ETIGTLAYNA-PEIILGD---
.||| |.|  |.|... .                 ..|..||  |....    .                         .  ||..| | ||...|    
NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

---------TQELGSGVDVWGAGVILAELVLGYNPFSVVRESHAA---------RELYRVVEEIKER-LHRE---------------IGDE-------DI
          .  |  .|.| .||||  .. || ||    ..            .||.. . . | .  . .               | ||       . 
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQEC

LELLDNMLVWEPEERWSAERALSSSFF
  |. .||. .||.|...| .|.  ..
KDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase CDC2-S1_e.AA CMGC 6-202 20 1.8e-46 150.15 In-house 1-331 (513) Show / Hide 
Range on Protein: 6-202
Range on HMM: 1-331/513
Sequence Identity: 20% (69 aa)

IDYSTRLGRGTGGTVREGIN--------------LDTMEKVAIKEMVEHLNLHEETK-------------LVYGLLQECQ----------------HGN-
 .   ..|.|| |.| ....               .| |.|||| . .    .|. |                 .|.. .                | | 
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IVKLLDVGSIGG-----------------KTYMVFEHMFGDLYKFKKRLGMLMKR----TLNREE------------IKTII------EQILQALA--YM
||||.|.    .                 . |.|||.|  |||.. |.   ....     |.  .            || ..       |||..|.  |.
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HEHG--IVHQDIKTANVLINKEGTK-------------------VKLCDFDHARRVTTPPRD----------------------PETIGTLAYNAPEIIL
| |.  |.| |.| .|.|||....                    .|.|||  || . .....                       . . |. | ||||.|
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

GDT--------QELGSGVDVWGAGVILAELVLG
|..        .. ....|.|..| |.||...|
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTG
Kinase CDC2-S1_e.AA STE 6-265 19 1.3e-39 137.51 In-house 1-359 (359) Show / Hide 
Range on Protein: 6-265
Range on HMM: 1-359/359
Sequence Identity: 19% (71 aa)

IDYSTRLGRGTGGTVREGINL------DTMEK---------VAIKEMVEHLN------------------LHEETKLVYGLLQECQ--HGNIVKLLDVGS
 .   ..|.|..|||  ..|       .| |.         .|||.|    .                   ... .    ....|.  | |||| ..   
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

IGG-------KTYMVFEHMFG----DLYKFKKRLGMLMK------RTLNREEIKTIIEQILQA-LAYMHEHGIVHQDIKTANVLINKEGTKVKLCDFDHA
 .|       . ... |.| |    |..| |.  |. ..       ... ..|..|. |||.. |.| |.|.|.| ||| ||.|.      |||||| ..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL------VKLCDFGVC

RRVTT--------------PPRDPET---IGTLAYNAPEIILGDT----QELGSGVDVWGAGVILAELVLGYNPFSVVRES----HAARE---------L
 ..|                 .. ..   .||  . |||.|....    .. .  .|.|  |  . |.. |  |..         .....         |
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

YRVVEEIKERLHREIGD------------------EDILELLDNMLVWEPEERWSAERALS--SSFF
  .|..   .|  .. .                  ..  . ... |. .|..|..|.  |.   .|.
-CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase CDC2-S1_e.AA CDK 53-206 33 3.4e-38 119.69 In-house 61-225 (284) Show / Hide 
Range on Protein: 53-206
Range on HMM: 61-225/284
Sequence Identity: 33% (61 aa)

LLQECQHGNIVKLLDVGSIG-----------GKTYMVFEHMFGDLYKFKKRLGMLMKRTLNREEIKTIIEQILQALAYMHEHGIVHQDIKTANVLINKEG
||.|. | |||||.||                | |||||.|  ||.|. .              ||... |.|..|.|.|...|.| |.|..| |||. |
LLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEYMDHDLKKYMD--------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNG

T----KVKLCDFDHARRVTTP-----PRDPET--IGTLAYNAPEIILGDTQEL-GSGVDVWGAGVILAELVL---GYNPF
.    ..|. ||  ||    |     |. . |  . || | |||. ||...   | ..|.|..| |.||...   .   |
EVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLF
Kinase CDC2-S1_e.AA Ciliate-E2 6-265 18 2.9e-36 121.96 In-house 1-365 (365) Show / Hide 
Range on Protein: 6-265
Range on HMM: 1-365/365
Sequence Identity: 18% (73 aa)

IDYSTRLGRGTGGTVREGINLDTMEKVAIK-----------------EMVEHLNLH----EETKLVYGLLQ----------------ECQHGNIVKLLDV
..    .|.|. |.|... .  . ...|||                  ...  ...    |..| .  ...                . .| ||.|. ..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

GS--IGGKTYMVFEHMFG-DLYK-----FKKRLGMLM-KRTLNREEIKTIIEQILQ---------------ALAYMHEHG-IVHQDIKTANVLINKEGTK
       . |.|.|   | ||..      |||.  .  .  .. .|||.|..||||               || |.|. . |.| |||  |.|.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

VKLCDFDHARRVTTPPRDPE--------------------------------TIGTLAYNAPEIILGDT-------QELGSGVDVWGAGVILAELVLGYN
.|..||  .......  .                                  ..||. | ||||. |         .. .  .|.| .|||| |.. |. 
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFSVVRESHAARELYRVVEEIKE-RLH-------------------REIGDEDILELLDN----MLVWEPEERWS-AERALSSSFF
||                ..||.  .                     .  ...   |. .    ||. .||.| . .| .|   .|
PF---------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase CDC2-S1_e.AA CAMKL 12-265 24 1e-34 108.1 In-house 7-297 (297) Show / Hide 
Range on Protein: 12-265
Range on HMM: 7-297/297
Sequence Identity: 24% (73 aa)

LGRGTGGTVREGIN-LDTMEKVAIKEMV-EHLNLHEETKLV---------------YGLLQECQ---HGNIVKLLDVGSIGGK------TYMVFEHMFGD
||.|. |.|. ... . | |||||| .  . ... . .|                 . ...  .   | ||.||..|     .       |.| |.  | 
LGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGG

---LYKFKKRLGMLMKRT-----LNREEIKTIIEQILQALAYMHEHGIVHQDIKTANVLINKEGT-KVKLCDFDHARRVT---TPPRD--PETIGTLAYN
   |. .      . |.      .  .| . .  ||. |..|.|.||||| |||  |.|. . |  ..|..||  .   .    .| .   .  |...| 
EMDLFDY------IVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEIILG-DTQELGSGVDVWGAGVILAELVLGYNPFSVV---RESHAARELYRVVEEIKERLHREIG-----DEDILELLDNMLVWEPEERWSAERALSS
||||..|  ..  |  ||.| .||||  .| || ||      .   .  . .   .... ..  ..      . |   |.  ||.  ||.| ...  .. 
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNK---QGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNH

SFF
 ..
PWM
Kinase CDC2-S1_e.AA CDC2 53-200 37 8.9e-34 100.79 In-house 53-203 (301) Show / Hide 
Range on Protein: 53-200
Range on HMM: 53-203/301
Sequence Identity: 37% (59 aa)

LLQECQ-HGNIVKLLDVGSIGGKTYMVFEHMFGDLYKFKKRLGMLMKRTLNREEIKTIIEQILQALAYMHEHGIVHQDIKTANVLINKEGTKVKLCDFDH
.|.| . | ||||| ||  .  | ||||| .  || |. ...   .   .  . .| .. ||||.... | ..|.| |.|  | ||.|.|. .|. ||  
CLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKN-KHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGN-IKIADFGL

ARRVTTPPRDPET----IGTLAYNAPEIILGDTQELGSGVDVWGAGVILAEL---V
|| ...| | ..|    . || | |||| ||. .    .||.|  | |.||.   |
ARAFGIPIR-TYTTEHEVVTLWYRAPEILLGCKR-YSTPVDMWSIGCIFAEMFMDV
Kinase CDC2-S1_e.AA Ciliate-E2-Unclassified 6-265 20 1.7e-33 113.56 In-house 1-352 (352) Show / Hide 
Range on Protein: 6-265
Range on HMM: 1-352/352
Sequence Identity: 20% (71 aa)

IDYSTRLGRGTGGTVREGINLDTMEKVAIKEMV--------------EHLNLHEETKLVY--------GLLQE----CQHGNIVKLLDVGSIGGKTYMVF
      .|.|  |.|.. .. .. .. |.|.|               |..|  .| .            ..|.    ..| .|||....     . |.| 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EHMFG-------DLYKF----KKRLGMLMKR--TLNREEIK-----TIIEQILQALAYMHEHG-IVHQDIKTANVLINKEGT--KVKLCDFDHARRVTT-
| . |         .|.    .. |.. ||.   .  ...|     ... ||||.| |.|. . |.| |||  |.|....|   ..|..||  ...  . 
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

---------------PPRDPETIGTLAYN----APEIILGDTQELG--SGVDVWGAGVILAELVLGYNPFSVVRESH----------------AARELYR
               . .   ..||. |     |||.. |  ..      .|.|. |||| |.. || ||.   .                    .. . 
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

VVEEIKERL------HREIGDEDILE-LLDNMLVWEPEERWSAERALSSSFF
   ....        |     .|... ||  ||.. |..| ..| .|   .|
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase CDC2-S1_e.AA ULK 6-207 25 7.5e-31 104.97 In-house 1-257 (329) Show / Hide 
Range on Protein: 6-207
Range on HMM: 1-257/329
Sequence Identity: 25% (66 aa)

IDYSTRLGRGTGGTVREGINLDT----MEKVAIKEMV---EHLNLHE-----ETKLVY---GLLQEC--------QHGNIVKLLDVGSIG--GKTYMVFE
.  . .|| |. |.| .|.| .|     ||||.| .    .  ...|       .|.     ....         .| |||||.|.        .|...|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

HMFG-DLYKFKKRLGMLM-----KRTLNREEIKTIIEQILQALAYMHEHGIVHQDIKTANVLINKEGTK-----------VKLCDFDHARRVTTP----P
   | || .. |. . |.     |..|. .|.. .. |||... ..|.|.|.| ||| .|.||..  .|           .|..||  |. |. .     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

RDPETI------GTLAYNAPEIILGD--TQELG-SGVDVWGAGVILAELVLGYNPFS
    .       ||  | ||.|. |    .. . . .|.|  |.|. |.. |. ||.
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFY
Kinase CDC2-S1_e.AA ULK 6-265 21 2.8e-30 104.67 In-house 1-324 (324) Show / Hide 
Range on Protein: 6-265
Range on HMM: 1-324/324
Sequence Identity: 21% (72 aa)

IDYSTRLGRGTGG-TVREGINLDT---MEKVAIKEMV---EHLNLHE--------ETKLVYGLLQECQ---HGN--IVKLLDVGSIG--GKTYMVFEHMF
.  . .|| |. | .| .|.| .|    ..||.| .       . .|          | .  ....     | |  ||||.|.        .|...|   
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

G-DLYKFKKRLGMLM----KRTLNREEIKTIIEQILQALAYMHEHGIVHQDIKTANVLINKEGTK-----------VKLCDFDHARRVTTP----PRDPE
| || .. |. . |.    |..|. .|.. .. ||.... ..|.|.|.| ||| .| ||..  .|           .|..||  |. |  .        .
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

TI------GTLAYNAPEIILGD--TQELG-SGVDVWGAGVILAELVLGYNPFSVVRESHAARELY----RVVE--------EIKERLHREIGD------E
.       ||  | ||.|. |    .. . . .|.|  |.|. |.. |. ||    .|  ....|    . ..        . .. .   ...      .
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPF----FSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISP

DILELLDNMLVWEPEERWSAERALSSSFF
.. .|.  ||. ....| | |  ..  .|
ECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase CDC2-S1_e.AA TyrKc 6-265 18 7e-13 -14.38 SMART 1-280 (280) Show / Hide 
Range on Protein: 6-265
Range on HMM: 1-280/280
Sequence Identity: 18% (56 aa)

IDYSTRLGRGTGGTVREGINLDTMEKVAIKEMVEHLNLHEETKLVY---GLLQEC--QHGNIVKLLDVGSIG-------GKTYMVFEHM-FGDLYKFKKR
|     ||.|  |.|..|.     ..||.| . |.       .  .    .. .   .| |||.|. | . .       .  ..|.|.|  ||| .. ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

LGMLMKRTLNREEIKTIIEQILQALAYMHEHGIVHQDIKTANVLINKEGTKVKLCDF----DHARR-------VTTPPR---DPETIGTLAYNAPEIILG
 .      |. ..   .  || .  .| |.....| |. . |.|.....  || .||    |.           .  ..   .  |   .   ||| |  
HRPK----LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--

DTQELGSGVDVWGAGVILAELV-LGYNPFSVV--RESHAARELYRVVEEIKERLHREI--------GDEDILELLDNMLVWEPEERWSAERALSSSFF
.. .  .  |||  || . |.  .|  | . .  .    ..|... |.. . .   .           ... ..       .||.| . .     ..|
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase CDC2-S1_e.AA CMGC 235-265 38 1e-11 33.82 In-house 483-513 (513) Show / Hide 
Range on Protein: 235-265
Range on HMM: 483-513/513
Sequence Identity: 38% (12 aa)

DEDILELLDNMLVWEPEERWSAERALSSSFF
|.. ..||..||...|..|..|| ||.  .|
DPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase CDC2-S1_e.AA CDK 240-265 46 5.1e-09 24.82 In-house 259-284 (284) Show / Hide 
Range on Protein: 240-265
Range on HMM: 259-284/284
Sequence Identity: 46% (12 aa)

ELLDNMLVWEPEERWSAERALSSSFF
.||..||. .|. |.||| ||.. .|
DLLNKMLCYDPKKRISAEQALQHPYF
Kinase CDC2-S1_e.AA CDC2 218-265 27 1.2e-07 19.0 In-house 254-301 (301) Show / Hide 
Range on Protein: 218-265
Range on HMM: 254-301/301
Sequence Identity: 27% (13 aa)

LYRVVEEIKERLHREIGDEDILELLDNMLVWEPEERWSAERALSSSFF
| .... ... .. .. |.. ..||..||. .|. | ||..||.  .|
LSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQHPYF
Kinase CDC2-S1_e.AA Pkinase_Tyr 6-149 25 2.8e-07 25.29 Pfam 1-155 (270) Show / Hide 
Range on Protein: 6-149
Range on HMM: 1-155/270
Sequence Identity: 25% (41 aa)

IDYSTRLGRGTGGTVREGINL----DTMEKVAIKEM------VE--HLNLHEETKLVYGLLQECQHGNIVKLLDVGS-IGGK--TYMVFEHMFG-DLYKF
|     ||.|  |.|..|.      .|  .||.| .       .  .  . .| |.   |   ..| |||.|. | .  |.    |.|.|.| . ||...
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQL---GHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

KKRLGMLMKRTLNREEIKTIIEQILQALAYMHEHGIVHQDIKTANVLINKEGTKVKLCDF
 ..     |. |. ...  .  || ....| ......| |. . |.|..... .|| |||
LRKHR-EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENN-VVKICDF
Kinase CDC2-S1_e.AA CDK 11-36 29 0.117926 0.88 In-house 6-36 (284) Show / Hide 
Range on Protein: 11-36
Range on HMM: 6-36/284
Sequence Identity: 29% (9 aa)

RLGRGTGGTVREGINLDTM-----EKVAIKE
..|.|| |.|  .....|      . ||.|.
KIGEGTYGVVYKARDKQTGRKKTGQIVALKK