Gene CDC2-S1_f (S.moellendorffii)

CDC2-S1_f

Species: S.moellendorffii
Alias: CDC2-S1_f
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDC2-smoe1

Sequence

Name Sequence Type Origin Length Description Download
CDC2-S1_f.AA Protein None 289 None Fasta, JSON
CDC2-S1_f.NA RNA None 870 None Fasta, JSON
CDC2-S1_f.kin_dom Protein Kinase Domain None 260 None Fasta, JSON

Protein domain

Protein domains of CDC2-S1_f.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase CDC2-S1_f.AA Pkinase 5-264 25 2.7e-62 218.09 Pfam 1-293 (293) Show / Hide 
Range on Protein: 5-264
Range on HMM: 1-293/293
Sequence Identity: 25% (75 aa)

IDYSTRLGRGTGGTVRGGINLDTMEKVAIKEMVEHLNLHEETKLV-----YGLLQECQHENIVKLLDVGSIGGKTYMVFEHMFGDLYKFKKRLGMLM---
.    ..|.|. |.|. ... .| ..||.|..  . . ... .         ......|.|||.|.|.   ... |||.|.. |.||       ...   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLY-VMDLFDYISTWR

KRTL--NREEIKTIIEQILQALAYMHEHGIVHQDIKTANVLINKEGTK---VKLCDFDHARRV-TTPPRDPETI-GTLAYNAPEIILGDTQELGSGVDVW
....    .|.| .. |||..|.|.|..||.| |.| .|.||...|.    ||.|||  |. . . . . . |. ||. | |||.|. . |. |. ||.|
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-GGQYYGPKVDMW

SAGVILAELVLGYNPFS--VVRESHAARELYRVVEEIKERLHREIG----------------------DEDILELLDNMLVWEPEERWSAERALSSTFF
|.|.||.|...|. ||.  .  . . .........  . .||...                       .|. .......| . |..|..|| .| . .|
SCGCILYEMLCGRPPFPGHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
S_TKc CDC2-S1_f.AA S_TKc 5-264 27 1.3e-59 205.23 SMART 1-231 (231) Show / Hide 
Range on Protein: 5-264
Range on HMM: 1-231/231
Sequence Identity: 27% (74 aa)

IDYSTRLGRGTGGTVRGGINLDTMEKVAIKEMVEHLNLHEETKLVYGLLQECQHENIVKLLDVGSIGGKTYMVFEHMFG---DLYKFKKRLGM-LMKRTL
 .    .|.|. |.|. ... .| ..||||..       | ..    .|.. .|.|||||.||    .. |||.|.. |   ||... |. |    .. .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

NREEIKTIIEQILQALAYMHEHGIVHQDIKTANVLINKEGTKVKLCDFDHARRVTTPPRDPETIGTLAYNAPEIILGDTQELGS-GVDVWSAGVILAELV
.  ... .. ||..||.|.|.|||.| |.| .|.|...    .|.|||  ||..         .||. | |||..       |   .|.|| |.||.|..
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL-----GYGKCKCDWWSCGCILYEML

LGYNPFSVVRESHAARELYRVVEEIKERLHREIGDEDILELLDNMLVWEPEERWSAERALS-------STFF
 || ||.         ......            ... .......|...||.|..|  ||          .|
CGYPPFP------QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CDC2-S1_f.AA CAMK 10-264 18 1.1e-47 151.33 In-house 1-425 (425) Show / Hide 
Range on Protein: 10-264
Range on HMM: 1-425/425
Sequence Identity: 18% (77 aa)

RLGRGTGGTVRGGINLDTM------------EKVAIKEM------------------VEHL---------NLHEETKLV--YGLLQECQ-------HENI
 ||||. |.|. .|.  |             .||||| .                  ...          . . . ..   . ... .|       |.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKLLDVGS------------IGGK--------TYMVF---EHMFGD------LYKFKKRLG----------MLMKRTLNREEIKTIIEQILQALAYMHEH
.||..|                 |         |||.   |.. |       . . ... .            ... .. .| .... ||..|..|.|.|
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHSH

GIVHQDIKTANVLINKEG----------------TKVKLCDFDHARRVTTPPRDP------------------------ETIGTLAYNA-PEIILGD---
.||| |.|  |.|... .                 ..|..||  |....    .                         .  ||..| | ||...|    
NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

---------TQELGSGVDVWSAGVILAELVLGYNPFSVVRESHAA---------RELYRVVEEIKER-LHRE---------------IGDE-------DI
          .  |  .|.||.||||  .. || ||    ..            .||.. . . | .  . .               | ||       . 
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQEC

LELLDNMLVWEPEERWSAERALSSTFF
  |. .||. .||.|...| .|.  ..
KDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase CDC2-S1_f.AA CMGC 5-201 21 1e-46 150.97 In-house 1-331 (513) Show / Hide 
Range on Protein: 5-201
Range on HMM: 1-331/513
Sequence Identity: 21% (70 aa)

IDYSTRLGRGTGGTVRGGIN--------------LDTMEKVAIKEMVEHLNLHEETK-------------LVYGLLQECQ-----------------HEN
 .   ..|.|| |.|  ...               .| |.|||| . .    .|. |                 .|.. .                 |.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IVKLLDVGSIGG-----------------KTYMVFEHMFGDLYKFKKRLGMLMKR----TLNREE------------IKTII------EQILQALA--YM
||||.|.    .                 . |.|||.|  |||.. |.   ....     |.  .            || ..       |||..|.  |.
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HEHG--IVHQDIKTANVLINKEGTK-------------------VKLCDFDHARRVTTPPRD----------------------PETIGTLAYNAPEIIL
| |.  |.| |.| .|.|||....                    .|.|||  || . .....                       . . |. | ||||.|
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

GDT--------QELGSGVDVWSAGVILAELVLG
|..        .. ....|.||.| |.||...|
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTG
Kinase CDC2-S1_f.AA STE 5-264 19 9.5e-42 145.02 In-house 1-359 (359) Show / Hide 
Range on Protein: 5-264
Range on HMM: 1-359/359
Sequence Identity: 19% (72 aa)

IDYSTRLGRGTGGTVRGGINL------DTMEK---------VAIKEMVEHLN------------------LHEETKLVYGLLQECQ--HENIVKLLDVGS
 .   ..|.|..|||  ..|       .| |.         .|||.|    .                   ... .    ....|.  |.|||| ..   
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

IGG-------KTYMVFEHMFG----DLYKFKKRLGMLMK------RTLNREEIKTIIEQILQA-LAYMHEHGIVHQDIKTANVLINKEGTKVKLCDFDHA
 .|       . ... |.| |    |..| |.  |. ..       ... ..|..|. |||.. |.| |.|.|.| ||| ||.|.      |||||| ..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL------VKLCDFGVC

RRVTT--------------PPRDPET---IGTLAYNAPEIILGDT----QELGSGVDVWSAGVILAELVLGYNPFSVVRES----HAARE---------L
 ..|                 .. ..   .||  . |||.|....    .. .  .|.|| |  . |.. |  |..         .....         |
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

YRVVEEIKERLHREIGD------------------EDILELLDNMLVWEPEERWSAERALS--STFF
  .|..   .|  .. .                  ..  . ... |. .|..|..|.  |.    |.
-CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase CDC2-S1_f.AA CDK 52-205 34 2.9e-40 126.4 In-house 61-225 (284) Show / Hide 
Range on Protein: 52-205
Range on HMM: 61-225/284
Sequence Identity: 34% (62 aa)

LLQECQHENIVKLLDVGSIG-----------GKTYMVFEHMFGDLYKFKKRLGMLMKRTLNREEIKTIIEQILQALAYMHEHGIVHQDIKTANVLINKEG
||.|. |.|||||.||                | |||||.|  ||.|. .              ||... |.|..|.|.|...|.| |.|..| |||. |
LLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEYMDHDLKKYMD--------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNG

T----KVKLCDFDHARRVTTP-----PRDPET--IGTLAYNAPEIILGDTQEL-GSGVDVWSAGVILAELVL---GYNPF
.    ..|. ||  ||    |     |. . |  . || | |||. ||...   | ..|.||.| |.||...   .   |
EVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLF
Kinase CDC2-S1_f.AA Ciliate-E2 5-264 19 6.4e-37 124.26 In-house 1-365 (365) Show / Hide 
Range on Protein: 5-264
Range on HMM: 1-365/365
Sequence Identity: 19% (74 aa)

IDYSTRLGRGTGGTVRGGINLDTMEKVAIK-----------------EMVEHLNLH----EETKLVYGLLQ----------------ECQHENIVKLLDV
..    .|.|. |.|. . .  . ...|||                  ...  ...    |..| .  ...                . .| ||.|. ..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

GS--IGGKTYMVFEHMFG-DLYK-----FKKRLGMLM-KRTLNREEIKTIIEQILQ---------------ALAYMHEHG-IVHQDIKTANVLINKEGTK
       . |.|.|   | ||..      |||.  .  .  .. .|||.|..||||               || |.|. . |.| |||  |.|.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

VKLCDFDHARRVTTPPRDPE--------------------------------TIGTLAYNAPEIILGDT-------QELGSGVDVWSAGVILAELVLGYN
.|..||  .......  .                                  ..||. | ||||. |         .. .  .|.||.|||| |.. |. 
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFSVVRESHAARELYRVVEEIKE-RLH-------------------REIGDEDILELLDN----MLVWEPEERWS-AERALSSTFF
||                ..||.  .                     .  ...   |. .    ||. .||.| . .| .|   .|
PF---------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase CDC2-S1_f.AA CDC2 52-199 38 1.1e-36 109.86 In-house 53-203 (301) Show / Hide 
Range on Protein: 52-199
Range on HMM: 53-203/301
Sequence Identity: 38% (60 aa)

LLQECQ-HENIVKLLDVGSIGGKTYMVFEHMFGDLYKFKKRLGMLMKRTLNREEIKTIIEQILQALAYMHEHGIVHQDIKTANVLINKEGTKVKLCDFDH
.|.| . |.||||| ||  .  | ||||| .  || |. ...   .   .  . .| .. ||||.... | ..|.| |.|  | ||.|.|. .|. ||  
CLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKN-KHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGN-IKIADFGL

ARRVTTPPRDPET----IGTLAYNAPEIILGDTQELGSGVDVWSAGVILAEL---V
|| ...| | ..|    . || | |||| ||. .    .||.|| | |.||.   |
ARAFGIPIR-TYTTEHEVVTLWYRAPEILLGCKR-YSTPVDMWSIGCIFAEMFMDV
Kinase CDC2-S1_f.AA CAMKL 11-264 24 1.4e-36 114.14 In-house 7-297 (297) Show / Hide 
Range on Protein: 11-264
Range on HMM: 7-297/297
Sequence Identity: 24% (74 aa)

LGRGTGGTVRGGIN-LDTMEKVAIKEMV-EHLNLHEETKLV---------------YGLLQECQ---HENIVKLLDVGSIGGK------TYMVFEHMFGD
||.|. |.|. ... . | |||||| .  . ... . .|                 . ...  .   |.||.||..|     .       |.| |.  | 
LGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGG

---LYKFKKRLGMLMKRT-----LNREEIKTIIEQILQALAYMHEHGIVHQDIKTANVLINKEGT-KVKLCDFDHARRVT---TPPRD--PETIGTLAYN
   |. .      . |.      .  .| . .  ||. |..|.|.||||| |||  |.|. . |  ..|..||  .   .    .| .   .  |...| 
EMDLFDY------IVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEIILG-DTQELGSGVDVWSAGVILAELVLGYNPFSVV---RESHAARELYRVVEEIKERLHREIG-----DEDILELLDNMLVWEPEERWSAERALSS
||||..|  ..  |  ||.||.||||  .| || ||      .   .  . .   .... ..  ..      . |   |.  ||.  ||.| ...  .. 
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNK---QGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNH

TFF
 ..
PWM
Kinase CDC2-S1_f.AA Ciliate-E2-Unclassified 5-264 20 1.4e-33 113.9 In-house 1-352 (352) Show / Hide 
Range on Protein: 5-264
Range on HMM: 1-352/352
Sequence Identity: 20% (72 aa)

IDYSTRLGRGTGGTVRGGINLDTMEKVAIKEMV--------------EHLNLHEETKLVY--------GLLQE----CQHENIVKLLDVGSIGGKTYMVF
      .|.|  |.|.  .. .. .. |.|.|               |..|  .| .            ..|.    ..|..|||....     . |.| 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EHMFG-------DLYKF----KKRLGMLMKR--TLNREEIK-----TIIEQILQALAYMHEHG-IVHQDIKTANVLINKEGT--KVKLCDFDHARRVTT-
| . |         .|.    .. |.. ||.   .  ...|     ... ||||.| |.|. . |.| |||  |.|....|   ..|..||  ...  . 
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

---------------PPRDPETIGTLAYN----APEIILGDTQELG--SGVDVWSAGVILAELVLGYNPFSVVRESH----------------AARELYR
               . .   ..||. |     |||.. |  ..      .|.|| |||| |.. || ||.   .                    .. . 
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

VVEEIKERL------HREIGDEDILE-LLDNMLVWEPEERWSAERALSSTFF
   ....        |     .|... ||  ||.. |..| ..| .|   .|
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase CDC2-S1_f.AA ULK 5-206 26 3.9e-32 109.51 In-house 1-257 (329) Show / Hide 
Range on Protein: 5-206
Range on HMM: 1-257/329
Sequence Identity: 26% (67 aa)

IDYSTRLGRGTGGTVRGGINLDT----MEKVAIKEMV---EHLNLHE-----ETKLVY---GLLQEC--------QHENIVKLLDVGSIG--GKTYMVFE
.  . .|| |. |.|  |.| .|     ||||.| .    .  ...|       .|.     ....         .|.|||||.|.        .|...|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

HMFG-DLYKFKKRLGMLM-----KRTLNREEIKTIIEQILQALAYMHEHGIVHQDIKTANVLINKEGTK-----------VKLCDFDHARRVTTP----P
   | || .. |. . |.     |..|. .|.. .. |||... ..|.|.|.| ||| .|.||..  .|           .|..||  |. |. .     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

RDPETI------GTLAYNAPEIILGD--TQELG-SGVDVWSAGVILAELVLGYNPFS
    .       ||  | ||.|. |    .. . . .|.|| |.|. |.. |. ||.
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFY
Kinase CDC2-S1_f.AA STE20 5-206 27 8.7e-27 95.1 In-house 1-228 (288) Show / Hide 
Range on Protein: 5-206
Range on HMM: 1-228/288
Sequence Identity: 27% (62 aa)

IDYSTRLGRGTGGTVRGGINLDTMEK----VAIKEM-VEHL----NLHEETKLVYGLLQECQHENIVKLLDVGSIG----GKTYMVFEHMFG----DLYK
 .   ..|.|. |.|  ... .| |.    |||| | .|.     .  |. .  .  ...|.|.|||| ..    .     . ..| |.. |    |..|
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

FKKRLGMLMKR-TLNREEIKTIIEQILQALAYMHEHGIVHQDIKTANVLINKEGTKVKLCDFDHARRVTT----P--PRDPETIGTLAYNAPEIILGDT-
.. ..|   |  ..| |.| .|  ..||.|.| |...|.| ||| .|.|....| .|||.||  .  .|.       ..    .||  . |||.|.... 
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDG-EVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEG

--QELGSGVDVWSAGVILAELVLGYNPFS
  .. .. .|.|| |  . |.. |  |..
PDKGYDYKCDIWSLGITAIEMAEGEPPYF
Kinase CDC2-S1_f.AA TyrKc 5-263 19 2.7e-13 -7.79 SMART 1-280 (280) Show / Hide 
Range on Protein: 5-263
Range on HMM: 1-280/280
Sequence Identity: 19% (57 aa)

IDYSTRLGRGTGGTVRGGINLDTMEKVAIKEMVEHLNLHEETKLVY---GLLQEC--QHENIVKLLDVGSIG-------GKTYMVFEHM-FGDLYKFKKR
|     ||.|  |.|. |.     ..||.| . |.       .  .    .. .   .|.|||.|. | . .       .  ..|.|.|  ||| .. ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

LGMLMKRTLNREEIKTIIEQILQALAYMHEHGIVHQDIKTANVLINKEGTKVKLCDF----DHARR-------VTTPPR---DPETIGTLAYNAPEIILG
 .      |. ..   .  || .  .| |.....| |. . |.|.....  || .||    |.           .  ..   .  |   .   ||| |  
HRPK----LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--

DTQELGSGVDVWSAGVILAELV-LGYNPFSVV--RESHAARELYRVVEEIKERLHREI--------GDEDILELLDNMLVWEPEERWSAERALSSTF
.. .  .  |||| || . |.  .|  | . .  .    ..|... |.. . .   .           ... ..       .||.| . .    . |
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase CDC2-S1_f.AA CMGC 234-264 38 2.9e-11 32.33 In-house 483-513 (513) Show / Hide 
Range on Protein: 234-264
Range on HMM: 483-513/513
Sequence Identity: 38% (12 aa)

DEDILELLDNMLVWEPEERWSAERALSSTFF
|.. ..||..||...|..|..|| ||.  .|
DPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase CDC2-S1_f.AA CDK 239-264 46 2.4e-08 22.66 In-house 259-284 (284) Show / Hide 
Range on Protein: 239-264
Range on HMM: 259-284/284
Sequence Identity: 46% (12 aa)

ELLDNMLVWEPEERWSAERALSSTFF
.||..||. .|. |.||| ||.. .|
DLLNKMLCYDPKKRISAEQALQHPYF
Kinase CDC2-S1_f.AA CDC2 217-264 27 1.1e-07 19.09 In-house 254-301 (301) Show / Hide 
Range on Protein: 217-264
Range on HMM: 254-301/301
Sequence Identity: 27% (13 aa)

LYRVVEEIKERLHREIGDEDILELLDNMLVWEPEERWSAERALSSTFF
| .... ... .. .. |.. ..||..||. .|. | ||..||.  .|
LSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQHPYF
Kinase CDC2-S1_f.AA Pkinase_Tyr 5-148 25 4.1e-07 24.73 Pfam 1-155 (270) Show / Hide 
Range on Protein: 5-148
Range on HMM: 1-155/270
Sequence Identity: 25% (41 aa)

IDYSTRLGRGTGGTVRGGINL----DTMEKVAIKEM------VE--HLNLHEETKLVYGLLQECQHENIVKLLDVGS-IGGK--TYMVFEHMFG-DLYKF
|     ||.|  |.|. |.      .|  .||.| .       .  .  . .| |.   |   ..|.|||.|. | .  |.    |.|.|.| . ||...
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQL---GHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

KKRLGMLMKRTLNREEIKTIIEQILQALAYMHEHGIVHQDIKTANVLINKEGTKVKLCDF
 ..     |. |. ...  .  || ....| ......| |. . |.|..... .|| |||
LRKHR-EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENN-VVKICDF
Kinase CDC2-S1_f.AA STE20 239-264 30 5.1e-05 14.61 In-house 263-288 (288) Show / Hide 
Range on Protein: 239-264
Range on HMM: 263-288/288
Sequence Identity: 30% (8 aa)

ELLDNMLVWEPEERWSAERALSSTFF
...|..|. .||.|..|.  |.  |.
DFVDKCLQKDPEKRPTASQLLKHPFI