Gene CDC2-S2_b (S.moellendorffii)

CDC2-S2_b

Species: S.moellendorffii
Alias: CDC2-S2_b
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDC2-smoe2

Sequence

Name Sequence Type Origin Length Description Download
CDC2-S2_b.AA Protein None 333 None Fasta, JSON
CDC2-S2_b.NA RNA None 1002 None Fasta, JSON
CDC2-S2_b.kin_dom Protein Kinase Domain None 284 None Fasta, JSON

Protein domain

Protein domains of CDC2-S2_b.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc CDC2-S2_b.AA S_TKc 7-294 25 1.7e-65 224.82 SMART 1-231 (231) Show / Hide 
Range on Protein: 7-294
Range on HMM: 1-231/231
Sequence Identity: 25% (78 aa)

ASDARLLGAGGDGEVRVGFHRETGDKVAMKKMYEHEYLYDAIINESEILEEVAHDNVVNLLGLTCNNQGTFMVMELMDG---SLSDVILSRK-------L
    |..| |. |.|. . |..|| .||.|..       . |..| .||..  |.|.|.|..   . .  .||||..||   .| |.| .|.       .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

GEHDIRAVMRQILEGLAWIHAHRIVHQDVKTSNVLVKRDGEKNKLVVKLADFAAARRLRTRPWSNKVGTLTFNAPELLKGATSFGT-AIDVWGAGCIFAE
 | ..| .|.||...|. .| |.|.| |.| .|.|. .       ..|..||  ||.|     .  .||. . |||.|    ..|. ..|.|  |||..|
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL-----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYE

MLLGSNPFDVTDEEDWDSLDYFVADFAKKLDIDGCGMGYQDRRRERARKRILEKMARWKAEDARSGIKDPDAVELLKRMLAIDPARRISAQDALK-----
|| |  ||.    ..   ..  .                                             .|.| ......|  ||..|..| .||.     
MLCGYPPFP----QMQMMFKKIG---------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDI

--MPYF
  .|.|
KCHPWF
Pkinase CDC2-S2_b.AA Pkinase 7-294 23 2e-60 211.83 Pfam 1-293 (293) Show / Hide 
Range on Protein: 7-294
Range on HMM: 1-293/293
Sequence Identity: 23% (75 aa)

ASDARLLGAGGDGEVRVGFHRETGDKVAMKKMYEHEYLYDAIIN-----ESEILEEVAHDNVVNLLGLTCNNQGTFMVMELMDG-----SLSDVIL---S
    | .|.|. |.|. . |. ||..||.|..  ..   .  ..     | .|. .. |.|.| |..   ...   ||||...|     .|.|.|    .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RKL--GEHDIRAVMRQILEGLAWIHAHRIVHQDVKTSNVLVKRDGEKNKLVVKLADFAAAR---RLRTRPWSNKVGTLTFNAPELLKGATSFGTAIDVWG
...   |.... .|.|||.||. .|...|.| |.| .|.|....|. .   ||..||  |.     . .  .  .||. . |||...|..  |...|.|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA-CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

AGCIFAEMLLGSNPFD--VTDEEDWDSLDYFVADFAK-KLDIDG----CGMGYQDRRRERARKRILEKMARWKAEDARSGIKDPDAVELLKRMLAIDPAR
.|||..|||.|  ||.  . .... .. .. ..   . .|. |     ... .  .|. . .          . .  .    .... ...|..|. ||..
CGCILYEMLCGRPPFPGHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H----------F-HWTF-HNWSEECKDFIKWCLCKDPKK

RISAQDALKMPYF
|..|...|. |.|
RPTAEQILQHPWF
Kinase CDC2-S2_b.AA CMGC 7-203 20 2.5e-42 136.3 In-house 1-342 (513) Show / Hide 
Range on Protein: 7-203
Range on HMM: 1-342/513
Sequence Identity: 20% (69 aa)

ASDARLLGAGGDGEVRVGFH--------------RETGDKVAMKKMYEHEYLYDAI------------INESEILEEVA-----------------HDNV
    . .| |  |.|  ...              .||. .||.||. . .|  .|             . | .||...                  | |.
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VNLLGLTCNNQ-----------------GTFMVMELMDGSLSDVILSRK----------LGEHD------------IRAVM------RQILEGLA--WIH
|.|.     ..                   ..|.|.|| .| ..| . .          | |              |.  |      .|||.||.   .|
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

AHR--IVHQDVKTSNVLVKRDGEK---------------NKLVVKLADFAAARRLRTR-----------------------PWSNKVGTLTFNAPELLKG
 |.  |.| | | .|.|.  ..|                 . ..|..||  || . ..                       | .. | |.   |||.| |
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

A---------TSFGTAIDVWGAGCIFAEMLLG-------SNPF
.         . ..|.||.|..|||||||..|         |.
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPL
Kinase CDC2-S2_b.AA CAMK 12-210 17 7.2e-41 128.95 In-house 1-341 (425) Show / Hide 
Range on Protein: 12-210
Range on HMM: 1-341/425
Sequence Identity: 17% (60 aa)

LLGAGGDGEVRVGFHRETG------------DKVAMKKMY-----------------------------EHEYLYDAIINESEILEEVA-------HDNV
 || |. |.|. ..|..|.             |||.| .                              . ..  . . .| ||.  .        | |.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VNLLGLTC------------NNQG--------TFMVM---ELMDG-----SLSDVILSR----------------KLGEHDIRAVMRQILEGLAWIHAHR
..|.                . .          .|||   |...|      | | | ..                .. |.. | ..|||..... .| | 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IVHQDVKTSNVLVKRDGEKNK------------LVVKLADFAAARRLRT-------------------------RPWSNKVGTLTFNA-PELLKG-----
||| | |  |.|.  ... .               .|..||  |....                           . .  .||. . | ||.|.|     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------ATSFGTAIDVWGAGCIFAEMLLGSNPFDVTDEED
         .  | ..|.| .|.|   || |  ||.  ....
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNE
Kinase CDC2-S2_b.AA CDK 54-203 32 3.4e-36 113.19 In-house 61-225 (284) Show / Hide 
Range on Protein: 54-203
Range on HMM: 61-225/284
Sequence Identity: 32% (56 aa)

ILEEVAHDNVVNLLGLTCNN-----------QGTFMVMELMDGSLSDVILSRKLGEHDIRAVMRQILEGLAWIHAHRIVHQDVKTSNVLVKRDGE-KNKL
.| |  |.|.|.|.     .              .||.| ||  |. ..         |.  |.|.|.||. .| ..|.| | |..| |. ..|| |   
LLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEYMDHDLKKYMD--------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVK-CG

VVKLADFAAARRL--------RTRPWSNKVGTLTFNAPELLKGATSFG--TAIDVWGAGCIFAEMLL---GSNPF
..|.|||  ||           .|. ...| ||   ||||| |..  .  |.||.|..|||||||..   .   |
RLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLF
Kinase CDC2-S2_b.AA STE 7-203 22 6e-36 124.46 In-house 1-268 (359) Show / Hide 
Range on Protein: 7-203
Range on HMM: 1-268/359
Sequence Identity: 22% (62 aa)

ASDARLLGAGGDGEVRVGFHRE---------------TGDKVAMKKMYEHEY------------------LYDAIINESEILEEVA--HDNVVNLLGLTC
  . . .| |. |.|  . ...               ||. .|.|.|   .                     . |..| .|. .    |.|.|. .|   
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

NN-------QGTFMVMELMD-GSLSDVIL---SRKLG------------EHDIRAVMRQILEG-LAWIHAHRIVHQDVKTSNVLVKRDGEKNKLVVKLAD
..       .  ...||.|| |||.|.|    ... .            |. |... ||||.| |. .| |.|.| |.| .|.|.          |||.|
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----------VKLCD

FAAARRLRT-----------------RPWS-NKVGTLTFNAPELLKG-----ATSFGTAIDVWGAGCIFAEMLLGSNPF
|  . .|                      .   |||  . ||| ...         .|  |.|  ||   ||. |  |.
FGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPW
Kinase CDC2-S2_b.AA CDK7 8-198 34 1.9e-35 91.52 In-house 2-198 (288) Show / Hide 
Range on Protein: 8-198
Range on HMM: 2-198/288
Sequence Identity: 34% (69 aa)

SDARLLGAGGDGEVRVGFHRETGDKVAMKKMY---EHEYLYDAI----INESEILEEVAHDNVVNLLGLTCNNQGTFMVMELMDGSLSDVILSRK--LGE
   ...|.|  . |  .   .|| .|| ||       .   | |    | |  || |  ||||..|.          .|...||  |  ||   .  |  
EKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKSNIQLVFDFMDWDLEVVIKDKSIILTP

HDIRAVMRQILEGLAWIHAHRIVHQDVKTSNVLVKRDGEKNKLVVKLADFAAARRLRT--RPWSNKVGTLTFNAPELLKGATSFGTAIDVWGAGCIFAEM
 .| | | ..| || . |.. | | | |  | |.  .|     ..|.|||  ||      | .. .| |  . ||||| || ..||..|.|  |||||| 
AHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENG-----QLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAEL

LL
.|
ML
Kinase CDC2-S2_b.AA Ciliate-E2 11-294 16 1.5e-33 112.53 In-house 5-365 (365) Show / Hide 
Range on Protein: 11-294
Range on HMM: 5-365/365
Sequence Identity: 16% (68 aa)

RLLGAGGDGEVRVGFHRETGDKVAMK-----------------KMYEHEYL----YDAIINESEILEEVA----------------HDNVVNLLGLTC--
...| |. | |. . ..... ..|.|                 |.|. ...      .| .|  |. |.                 |.|....       
KKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEK

NNQGTFMVMELMDG-SLSDVILSR------------KLGEHDIRAVMRQILE---------------GLAWIHAHR-IVHQDVKTSNVLVKRDGEKNKLV
...  ..|||. .| .| | | ..            .. |  |. .|.|||.               .|  .|    |.| | | .|.|.          
DDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----------

VKLADFAAARRLRTRPWSNK---------------------------------VGTLTFNAPELLKGATS--------FGTAIDVWGAGCIFAEMLLGSN
.|..||  .... .    .                                  .||. . ||| |.|            ....|.| .|.|. ||| |  
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFDVTDEEDWDSLDYFVADFAKKLDIDGCGMGYQDRRRERARKRILEKMA-RWKAEDAR-------------SGIKDPDA-VELLKR----MLAIDPARR
||                                          . ...   ..   .              |  | ..    |.|.    ||  ||  |
PF------------------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKR

IS-AQDALKMPYF
|. ....|. |.|
ITGWEQILNHPWF
Kinase CDC2-S2_b.AA TKL 13-204 18 8e-32 111.86 In-house 1-290 (364) Show / Hide 
Range on Protein: 13-204
Range on HMM: 1-290/364
Sequence Identity: 18% (55 aa)

LGAGGDGEVRVGFHRE--------TGDKVAMKKMYEHE----------------------------YLYDAIINESEILEEVAHDNVVNLLGLTCNNQG-
.| || |||  | .|         ||  ||.||. .|.                             . . ...|  ..    |.|.| ..|  |.... 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------TFMVMELM-DGSLSDVILSRKLGEHDIRAVMRQILEGLAWIHAHR--------IVHQDVKTSNVLVKRDGE---------KNKLVVKL
             ..|||..  ||| ....      | .   ...|  |... |...        |.| | |..|.||.....         ..  ..|.
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKI

ADFAAARRLRTRP---------------------WSNKVGTLTFNAPELLKGAT---------------SFGTAIDVWGAGCIFAEMLLGSNPFD
.||  .|.. ..                       ....||. . |||.|.|..               .. ...||.  | .. |.| .  |..
CDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYY
Kinase CDC2-S2_b.AA CRK7 54-197 27 1e-25 85.53 In-house 54-247 (343) Show / Hide 
Range on Protein: 54-197
Range on HMM: 54-247/343
Sequence Identity: 27% (54 aa)

ILEEVAHDNVVNLLGLTCN--------NQG--TFMVMELMDGSLSDVILSR--K-LGEHDIRAVMRQILEGLAWIHAHRIVHQDVKTSNVLVKRDGEKNK
|| .  |.|.|||              ..   ..|| | ||  |.   .|   .   .  ..  |.|.|||.. .|   . | |.| ||.|.   ||   
ILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMGLLESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGE---

LVVKLADFAAARRLRT----RPWSNKVGTLTFNAPELLKGATSF--------------------------------------GTAIDVWGAGCIFAEML
  ||.|||  || .      ||  |.| ||   .|||| |..                                        |..||.|. |||..| .
--VKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHILKELIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELF
Kinase CDC2-S2_b.AA CDC2 19-196 31 1.3e-25 75.22 In-house 13-199 (301) Show / Hide 
Range on Protein: 19-196
Range on HMM: 13-199/301
Sequence Identity: 31% (61 aa)

GEVRVGFHRETGDKVAMKKM-YEHEYLY----DAIINESEILEEVA-HDNVVNLLGLTCNNQGTFMVMELMDGSLSDVIL----S-RKLGEHDIRAVMRQ
|.|  . ...|.. ||.||   |.|         .| |  .| |   |.|.| |     . .  .|| | .|  |         .  .. .. ..  | |
GVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKHMPPQLVKSYMYQ

ILEGLAWIHAHRIVHQDVKTSNVLVKRDGEKNKLVVKLADFAAARRLRT--RPWS--NKVGTLTFNAPELLKGATSFGTAIDVWGAGCIFAEM
||.|..  |..||.| | | .| |. ..|.     .|.|||  ||   .  |.      | ||   |||.| |.    |..|.|  |||||||
ILQGVHFCHQRRIMHRDLKPQNILIDKKGN-----IKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEM
Kinase CDC2-S2_b.AA RCK 13-195 32 9.1e-23 68.81 In-house 7-206 (298) Show / Hide 
Range on Protein: 13-195
Range on HMM: 7-206/298
Sequence Identity: 32% (65 aa)

LGAGGDGEVRVGFHRETGDKVAMKKMYEHEYLYDAIINESEI--LEEVA-HDNVVNLLGLTCNNQ--GTFMVMELMDGSLSDVILS----RK-LGEHD--
||.|  |.|  .   |||..||.|||  . |  . ..|  ||  |  .  |.|...|.    .|     . |.|.||  |.  . .    || | |    
LGDGTYGCVMKAQNKETGEIVAIKKMKQKFYSWEECMNLREIKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFEYMDMNLYQMMKDFKERRKYLPENQRS

IRAVMRQILEGLAWIHAHRIVHQDVKTSNVLVKRD----GEKNKLVVKLADFAAARRLRTRP-WSNKVGTLTFNAPELLKGATSFGTAIDVWGAGCIFAE
|.  | ||| ||| .| | . | |.|  | ... .     ...  ..|.|||  .|  | .|     |.|    |||.|  .|   . .|.|. |||..|
IKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRSKPPYTDYVSTRWYRAPECLLRCTYYNSPMDIWAVGCIMYE
Kinase CDC2-S2_b.AA CDK7 266-294 37 1.6e-16 40.08 In-house 260-288 (288) Show / Hide 
Range on Protein: 266-294
Range on HMM: 260-288/288
Sequence Identity: 37% (11 aa)

DAVELLKRMLAIDPARRISAQDALKMPYF
|...|...|.. .| .|... ..||||||
DLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase CDC2-S2_b.AA CDC2 252-294 37 1.2e-15 44.03 In-house 248-301 (301) Show / Hide 
Range on Protein: 252-294
Range on HMM: 248-301/301
Sequence Identity: 37% (20 aa)

RWKAEDARSGIKD-----------PDAVELLKRMLAIDPARRISAQDALKMPYF
|||. | .. ...           |....||..||..||..||||..||. |||
RWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQHPYF
Kinase CDC2-S2_b.AA CMGC 264-294 58 4.2e-15 45.17 In-house 483-513 (513) Show / Hide 
Range on Protein: 264-294
Range on HMM: 483-513/513
Sequence Identity: 58% (18 aa)

DPDAVELLKRMLAIDPARRISAQDALKMPYF
||.|..|||.|| .||..||.|..||..|||
DPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase CDC2-S2_b.AA RCK 265-294 53 1.2e-14 42.65 In-house 269-298 (298) Show / Hide 
Range on Protein: 265-294
Range on HMM: 269-298/298
Sequence Identity: 53% (16 aa)

PDAVELLKRMLAIDPARRISAQDALKMPYF
.|..||.. ||..||  ||.|| ||..|||
QDCIELMEKMLQWDPQKRITAQQALQHPYF
Kinase CDC2-S2_b.AA CDK 247-294 33 1e-13 40.09 In-house 252-284 (284) Show / Hide 
Range on Protein: 247-294
Range on HMM: 252-284/284
Sequence Identity: 33% (16 aa)

LEKMARWKAEDARSGIKDPDAVELLKRMLAIDPARRISAQDALKMPYF
..|.  .               .|| .||. ||..||||..||..|||
VTKLPDY---------------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase CDC2-S2_b.AA TyrKc 7-294 18 5.3e-12 -28.66 SMART 1-280 (280) Show / Hide 
Range on Protein: 7-294
Range on HMM: 1-280/280
Sequence Identity: 18% (61 aa)

ASDARLLGAGGDGEVRVGFHRETGDKVAMKKMYEHEYLYDAIINESEILEEV--AHDNVVNLLGLTCNN-------QGTFMVMELMD-GSLSDVILSRK-
 .  . || |  |||. |  .    .|| |.. |.     ....| .|. ..   |.|.|.|.|            .  ..|||.|. |.| | . ... 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

-LGEHDIRAVMRQILEGLAWIHAHRIVHQDVKTSNVLVKRDGEKNKLVVKLADFAAARRLRTR------PWSNKV-----GT--LTFN--APELLKGATS
 |   |    . || .| . .| ....| |  . |.||....     .|| .||  .| .             ..     |   |     ||| .   ..
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NYG

-FGTAIDVWGAGCIFAEML-LGSNPFD------VTDEEDWDSLDYFVADFAKKL----DIDGCGMGYQDRRRERARKRILEKMARWKAEDARSGIKDPDA
 | |. |||  |    |.. .|  |        ....|    ..        .                                       . .  .. 
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS---------------------------------FVCCPDEM

VELLKRMLAIDPARRISAQDALKMPYF
 .. |.  . ||. | . ..     .|
YQIMKQCWHEDPEDRPTFSEI--HECF
Kinase CDC2-S2_b.AA CRK7 264-294 32 8.6e-10 29.74 In-house 313-343 (343) Show / Hide 
Range on Protein: 264-294
Range on HMM: 313-343/343
Sequence Identity: 32% (10 aa)

DPDAVELLKRMLAIDPARRISAQDALKMPYF
..... ||  ||. ||  |..|...|  ..|
PKECLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase CDC2-S2_b.AA Pkinase_Tyr 19-148 25 1.1e-09 33.36 Pfam 13-155 (270) Show / Hide 
Range on Protein: 19-148
Range on HMM: 13-155/270
Sequence Identity: 25% (38 aa)

GEVRVGFHR----ETGDKVAMKKM---YEHEY-LYDAIINESEILEEV-AHDNVVNLLGLTC-NNQG--TFMVMELMDG-SLSDVILSR-----KLGEHD
|||. |  .    .|. .|| |..   . ||  . .. ..| .|. .   |.|.|.|.|      .    ..|||.| . .| |   ..     .|  .|
GEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKD

IRAVMRQILEGLAWIHAHRIVHQDVKTSNVLVKRDGEKNKLVVKLADF
.    .|| .|... ......| |. . |.||..     ..||| .||
LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE-----NNVVKICDF
Kinase CDC2-S2_b.AA CAMK 264-294 25 4.3e-08 21.41 In-house 395-425 (425) Show / Hide 
Range on Protein: 264-294
Range on HMM: 395-425/425
Sequence Identity: 25% (8 aa)

DPDAVELLKRMLAIDPARRISAQDALKMPYF
....  |...||  || .|......|. | .
SQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase CDC2-S2_b.AA STE 262-294 17 0.000292 11.09 In-house 303-359 (359) Show / Hide 
Range on Protein: 262-294
Range on HMM: 303-359/359
Sequence Identity: 17% (10 aa)

IKD----------------------PDAVELLKRMLAIDPARRISAQDALK--MPYF
..|                      |.  . ... | .||  | .|.. ||   | .
LPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI