Gene CDC2-S2_m (S.moellendorffii)

CDC2-S2_m

Species: S.moellendorffii
Alias: CDC2-S2_m
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDC2-smoe2

Sequence

Name Sequence Type Origin Length Description Download
CDC2-S2_m.AA Protein None 360 None Fasta, JSON
CDC2-S2_m.NA RNA None 1083 None Fasta, JSON
CDC2-S2_m.kin_dom Protein Kinase Domain None 284 None Fasta, JSON

Protein domain

Protein domains of CDC2-S2_m.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc CDC2-S2_m.AA S_TKc 31-318 26 4.7e-66 226.69 SMART 1-231 (231) Show / Hide 
Range on Protein: 31-318
Range on HMM: 1-231/231
Sequence Identity: 26% (80 aa)

ASDARLLGAGADGEVRVGFHRKTGDKVAMKKMYEHEYLYDTIINESEILEEVAHDNVVNLLGLTCNNQGTFMVMELMDG---SLRDVVSSRK-------L
    |..| || |.|. . |.||| .||.|..       ..|..| .||..  |.|.|.|..   . .  .||||..||   .|.|.  .|.       .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

GEHDIKAVMRQILEGLAWIHAHRIVHQDIKTSNVLVKRDGEKNKLVVKLADFTTARRLQTRPWSNEVGTLTFNAPELLKGATSFGT-AIDVWGAGCIFAE
 | ... .|.||...|. .| |.|.| |.| .|.|. .       ..|..||  ||.|     .  .||. . |||.|    ..|. ..|.|  |||..|
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL-----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYE

MLLGSNPFDVPDEEDGDSLNYFVADFAKKLDIDGCGMGYQDRRRERARERILEKMAWWKAEDVRSGIKDPNAVELLKRMLAIDPARRISAQNALK-----
|| |  ||.             ..   ||.                                      .| | ......|  ||..|..|  ||.     
MLCGYPPFP------------QMQMMFKKIG-------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDI

--MPYF
  .|.|
KCHPWF
Pkinase CDC2-S2_m.AA Pkinase 31-318 24 2.8e-62 218.01 Pfam 1-293 (293) Show / Hide 
Range on Protein: 31-318
Range on HMM: 1-293/293
Sequence Identity: 24% (76 aa)

ASDARLLGAGADGEVRVGFHRKTGDKVAMKKMYEHEYLYDTIIN-----ESEILEEVAHDNVVNLLGLTCNNQGTFMVMELMDG-----SLRDVVS---S
    | .|.|. |.|. . |..||..||.|..  ..   .  ..     | .|. .. |.|.| |..   ...   ||||...|     .| |..|   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RKL--GEHDIKAVMRQILEGLAWIHAHRIVHQDIKTSNVLVKRDGEKNKLVVKLADFTTAR---RLQTRPWSNEVGTLTFNAPELLKGATSFGTAIDVWG
...   |...| .|.|||.||. .|...|.| |.| .|.|....|. .   ||..||  |.       .  .  .||. . |||...|..  |...|.|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA-CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

AGCIFAEMLLGSNPFDVP----DEEDGDSLNYFVADFAKKLDID--GCGMGYQDRRRERARERILEKMAWWKAEDVRSGIKDPNAVELLKRMLAIDPARR
.|||..|||.|  ||.      .  | . . . . .   . |..   ... .  .|. . .          . . ..    .... ...|..|. ||..|
CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H----------F-HWTF-HNWSEECKDFIKWCLCKDPKKR

ISAQNALKMPYF
..|. .|. |.|
PTAEQILQHPWF
Kinase CDC2-S2_m.AA CMGC 31-227 19 1.6e-45 147.02 In-house 1-342 (513) Show / Hide 
Range on Protein: 31-227
Range on HMM: 1-342/513
Sequence Identity: 19% (67 aa)

ASDARLLGAGADGEVRVGFH--------------RKTGDKVAMKKMYEHEYLYD------------TIINESEILEEVA-----------------HDNV
    . .| |. |.|  ...              ..|. .||.||. . .|  .            ... | .||...                  | |.
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VNLLGLTCNNQ-----------------GTFMVMELMDGSLRDVVSSRK----------LGEHD------------IKAVM------RQILEGLA--WIH
|.|.     ..                   ..|.|.|| .| ..  . .          | |              ||  |      .|||.||.   .|
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

AHR--IVHQDIKTSNVLVKRDGEK---------------NKLVVKLADFTTARRLQTR-----------------------PWSNEVGTLTFNAPELLKG
 |.  |.| |.| .|.|.  ..|                 . ..|..||  || . ..                       | ...| |.   |||.| |
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

A---------TSFGTAIDVWGAGCIFAEMLLG-------SNPF
.         . ..|.||.|..|||||||..|         |.
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPL
Kinase CDC2-S2_m.AA CDK 78-227 33 4.3e-39 122.6 In-house 61-225 (284) Show / Hide 
Range on Protein: 78-227
Range on HMM: 61-225/284
Sequence Identity: 33% (58 aa)

ILEEVAHDNVVNLLGLTCNN-----------QGTFMVMELMDGSLRDVVSSRKLGEHDIKAVMRQILEGLAWIHAHRIVHQDIKTSNVLVKRDGE-KNKL
.| |  |.|.|.|.     .              .||.| ||  |  . .        ||  |.|.|.||. .| ..|.| |.|..| |. ..|| |   
LLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEYMDHDLKKYMD--------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVK-CG

VVKLADFTTARRLQ--------TRPWSNEVGTLTFNAPELLKGATSFG--TAIDVWGAGCIFAEMLL---GSNPF
..|.|||  ||  .        .|. ..|| ||   ||||| |..  .  |.||.|..|||||||..   .   |
RLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLF
Kinase CDC2-S2_m.AA STE 31-227 22 2.5e-38 132.99 In-house 1-268 (359) Show / Hide 
Range on Protein: 31-227
Range on HMM: 1-268/359
Sequence Identity: 22% (64 aa)

ASDARLLGAGADGEVRVGFHRK---------------TGDKVAMKKMYEHEY------------------LYDTIINESEILEEVA--HDNVVNLLGLTC
  . . .| || |.|  . ..|               ||. .|.|.|   .                     . |..| .|. .    |.|.|. .|   
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

NN-------QGTFMVMELMD-GSLRDVVS---SRKLG------------EHDIKAVMRQILEG-LAWIHAHRIVHQDIKTSNVLVKRDGEKNKLVVKLAD
..       .  ...||.|| |||.|..    ... .            |. |... ||||.| |. .| |.|.| ||| .|.|.          |||.|
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----------VKLCD

FTTARRLQT-----------------RPWS-NEVGTLTFNAPELLKG-----ATSFGTAIDVWGAGCIFAEMLLGSNPF
| .. .|.                     .   |||  . ||| ...         .|  |.|  ||   ||. |  |.
FGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPW
Kinase CDC2-S2_m.AA CAMK 36-234 16 2.9e-38 120.42 In-house 1-341 (425) Show / Hide 
Range on Protein: 36-234
Range on HMM: 1-341/425
Sequence Identity: 16% (58 aa)

LLGAGADGEVRVGFHRKTG------------DKVAMKKMY-----------------------------EHEYLYDTIINESEILEEVA-------HDNV
 || |. |.|. ..|..|.             |||.| .                              . ..  . . .| ||.  .        | |.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VNLLGLTC------------NNQG--------TFMVM---ELMDG-----SLRDVVSSR----------------KLGEHDIKAVMRQILEGLAWIHAHR
..|.                . .          .|||   |...|      | | . ..                .. |.. . ..|||..... .| | 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IVHQDIKTSNVLVKRDGEKNK------------LVVKLADFTTARRLQT-------------------------RPWSNEVGTLTFNA-PELLKG-----
||| |.|  |.|.  ... .               .|..||  |....                           . .  .||. . | ||.|.|     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------ATSFGTAIDVWGAGCIFAEMLLGSNPFDVPDEED
         .  | ..|.| .|.|   || |  ||. .....
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNE
Kinase CDC2-S2_m.AA CDK7 32-222 34 1.1e-36 94.91 In-house 2-198 (288) Show / Hide 
Range on Protein: 32-222
Range on HMM: 2-198/288
Sequence Identity: 34% (69 aa)

SDARLLGAGADGEVRVGFHRKTGDKVAMKKMY---EHEYLYDTI----INESEILEEVAHDNVVNLLGLTCNNQGTFMVMELMDGSLRDVVSSRK--LGE
   ...|.|  . |  .   .|| .|| ||       .   | |    | |  || |  ||||..|.          .|...||  |  |.   .  |  
EKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKSNIQLVFDFMDWDLEVVIKDKSIILTP

HDIKAVMRQILEGLAWIHAHRIVHQDIKTSNVLVKRDGEKNKLVVKLADFTTARRLQT--RPWSNEVGTLTFNAPELLKGATSFGTAIDVWGAGCIFAEM
 .||| | ..| || . |.. | | |.|  | |.  .|     ..|.|||  ||      | ..  | |  . ||||| || ..||..|.|  |||||| 
AHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENG-----QLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAEL

LL
.|
ML
Kinase CDC2-S2_m.AA Ciliate-E2 35-318 16 2e-36 122.54 In-house 5-365 (365) Show / Hide 
Range on Protein: 35-318
Range on HMM: 5-365/365
Sequence Identity: 16% (70 aa)

RLLGAGADGEVRVGFHRKTGD---------------------------KVAMKKMYEHEYLYDTII----------NESEILEEVAHDNVVNLLGLTC--
...| |. | |. . ..|..                            |. .|.. |.    . |.          || .|||.. |.|....       
KKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEK

NNQGTFMVMELMDG-SLRDVVSSR------------KLGEHDIKAVMRQILE---------------GLAWIHAHR-IVHQDIKTSNVLVKRDGEKNKLV
...  ..|||. .| .|.|   ..            .. |  || .|.|||.               .|  .|    |.| ||| .|.|.          
DDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----------

VKLADFTTARRLQTR-----------PWSNEV-----------------------GTLTFNAPELLKGATS--------FGTAIDVWGAGCIFAEMLLGS
.|..|| .......             . .                         ||. . ||| |.|            ....|.| .|.|. ||| | 
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

NPFDVPDEEDGDSLNYFVADFAKKLDIDGCGMGYQDRRRERARERILEKMAWWKAEDVRSGIKD-------------------PNAVELLKR----MLAI
 ||                                              .   |  ...   ..                   ...  |.|.    ||  
PPF----------------------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQK

DPARRIS-AQNALKMPYF
||  ||. .. .|. |.|
DPEKRITGWEQILNHPWF
Kinase CDC2-S2_m.AA TKL 37-234 17 5.8e-34 119.15 In-house 1-296 (364) Show / Hide 
Range on Protein: 37-234
Range on HMM: 1-296/364
Sequence Identity: 17% (54 aa)

LGAGADGEVRVGFHRK--------TGDKVAMKKMYEHE----------------------------YLYDTIINESEILEEVAHDNVVNLLGLTCNNQG-
.| |. |||  | .|         ||  ||.||. .|.                             . .....|  ..    |.|.| ..|  |.... 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------TFMVMELM-DGSLRDVVSSRKLGEHDIKAVMRQILEGLAWIHAHR--------IVHQDIKTSNVLVKRDGE---------KNKLVVKL
             ..|||..  |||....       | .   ...|  |... |...        |.| |.|..|.||.....         ..  ..|.
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKI

ADFTTARRLQTRP---------------------WSNEVGTLTFNAPELLKGAT---------------SFGTAIDVWGAGCIFAEMLLGSNPFDVPDEE
.|| ..|.....                       ....||. . |||.|.|..               .. ...||.  | .. |.| .  |.. ....
CDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYM

D
.
P
Kinase CDC2-S2_m.AA CDC2 32-220 32 8.1e-33 97.8 In-house 2-199 (301) Show / Hide 
Range on Protein: 32-220
Range on HMM: 2-199/301
Sequence Identity: 32% (66 aa)

SDARLLGAGADGEVRVGFHRKTGDKVAMKKM-YEHEYLY----DTIINESEILEEVA-HDNVVNLLGLTCNNQGTFMVMELMDGSLRDVVS----S-RKL
   . .| |  |.|  . ...|.. ||.||   |.|        |.| |  .| |   |.|.| |     . .  .|| | .|  |.        .  ..
QKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKHM

GEHDIKAVMRQILEGLAWIHAHRIVHQDIKTSNVLVKRDGEKNKLVVKLADFTTARRLQT--RPWS--NEVGTLTFNAPELLKGATSFGTAIDVWGAGCI
 .. .|  | |||.|..  |..||.| |.| .| |. ..|.     .|.|||  ||  ..  |.     || ||   |||.| |.    |..|.|  |||
PPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGN-----IKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCI

FAEM
||||
FAEM
Kinase CDC2-S2_m.AA CDK5 32-220 35 1.1e-28 87.41 In-house 2-192 (287) Show / Hide 
Range on Protein: 32-220
Range on HMM: 2-192/287
Sequence Identity: 35% (69 aa)

SDARLLGAGADGEVRVGFHRKTGDKVAMKKM---YEHEYLYDTIINESEILEEVAHDNVVNLLGLTCNNQGTFMVMELMDGSLRDVVSSRK--LGEHDIK
.    .| |  | |  .  ..|.  ||.|.     | |    | | |  .| |  | |.| |      ..   .| | .|  |.    |..  .  | ||
EKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNGEMDMHIIK

AVMRQILEGLAWIHAHRIVHQDIKTSNVLVKRDGEKNKLVVKLADFTTARR--LQTRPWSNEVGTLTFNAPELLKGATSFGTAIDVWGAGCIFAEM
  | | | |||  |.|.. | | |  | |. . ||      |||||  ||      | .| || || . .|  | |.  . | ||.| .|||||||
SFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGE-----LKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEM
Kinase CDC2-S2_m.AA MAPK 31-223 26 7.7e-24 79.15 In-house 1-231 (328) Show / Hide 
Range on Protein: 31-223
Range on HMM: 1-231/328
Sequence Identity: 26% (63 aa)

ASDARLLGAGADGEVRVGFHRK------TGDKVAMKKMY---EHEYLYDTIINESEILEEV-AHDNVVNLLGLTCNN----QGT-------FMVMELMDG
  . . .| || | |   ....      .|.||| ||.    ... .   .. |  .| .   |.|...||          |..        .|||||. 
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

SLRDVVSSRK-LGEHDIKAVMRQILEG--LAWIHAHRIVHQDIKTSNVLVKRDGEKNKLVVKLADFTTARRLQTRP----------------WSNEVGTL
 |. .  |.. | .. |.  | ||| |  |  ||  ...| |.| ||.||  ...     .|..||  || . .                   .  | | 
DLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCD-----LKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATR

TFNAPELLKG--ATSFGTAIDVWGAGCIFAEMLL-G
   |||.. .  ..   .|.|.| .||||||||  .
WYRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDR
Kinase CDC2-S2_m.AA CDC2 288-318 54 4.2e-15 42.36 In-house 271-301 (301) Show / Hide 
Range on Protein: 288-318
Range on HMM: 271-301/301
Sequence Identity: 54% (17 aa)

DPNAVELLKRMLAIDPARRISAQNALKMPYF
||....||..||..||..||||. ||. |||
DPEGIDLLMQMLQYDPQKRISAKEALQHPYF
Kinase CDC2-S2_m.AA CDK7 291-318 35 8.5e-15 35.41 In-house 261-288 (288) Show / Hide 
Range on Protein: 291-318
Range on HMM: 261-288/288
Sequence Identity: 35% (10 aa)

AVELLKRMLAIDPARRISAQNALKMPYF
...|...|.. .| .|...  .||||||
LLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase CDC2-S2_m.AA CMGC 288-318 58 1.8e-13 39.75 In-house 483-513 (513) Show / Hide 
Range on Protein: 288-318
Range on HMM: 483-513/513
Sequence Identity: 58% (18 aa)

DPNAVELLKRMLAIDPARRISAQNALKMPYF
|| |..|||.|| .||..||.|. ||..|||
DPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase CDC2-S2_m.AA CDK 271-318 33 2.5e-13 38.83 In-house 252-284 (284) Show / Hide 
Range on Protein: 271-318
Range on HMM: 252-284/284
Sequence Identity: 33% (16 aa)

LEKMAWWKAEDVRSGIKDPNAVELLKRMLAIDPARRISAQNALKMPYF
..|. ..               .|| .||. ||..||||. ||..|||
VTKLPDY---------------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase CDC2-S2_m.AA TyrKc 31-318 19 4.2e-12 -26.98 SMART 1-280 (280) Show / Hide 
Range on Protein: 31-318
Range on HMM: 1-280/280
Sequence Identity: 19% (63 aa)

ASDARLLGAGADGEVRVGFHRKTGDKVAMKKMYEHEYLYDTIINESEILEEV--AHDNVVNLLGLTCNN-------QGTFMVMELMD-GSLRDVVSSRK-
 .  . || || |||. |  .    .|| |.. |.      ...| .|. ..   |.|.|.|.|            .  ..|||.|. |.|.|   ... 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

-LGEHDIKAVMRQILEGLAWIHAHRIVHQDIKTSNVLVKRDGEKNKLVVKLADFTTARRL-----------QTRP----WSNEVGTLTFNAPELLKGATS
 |   |    . || .| . .| ....| |. . |.||....     .|| .||  .| .             |.     .. .  .   ||| .   ..
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NYG

-FGTAIDVWGAGCIFAEML-LGSNPFDVPDEEDGDSLNYFVADFAKKLDIDGCGMG----YQDRRRERARERILEKMAWWKAEDVRSGIKDPNAVELLKR
 | |. |||  |    |.. .|  |   . ..  .  |. |  . |. .   .                                 . .  .   .. |.
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ--MMSNQEVIEYVKQGYRMPQPPNDYPMS-------------------------FVCCPDEMYQIMKQ

MLAIDPARRISAQNALKMPYF
  . ||. | . ..     .|
CWHEDPEDRPTFSEI--HECF
Kinase CDC2-S2_m.AA MAPK 286-318 45 4.2e-11 34.42 In-house 296-328 (328) Show / Hide 
Range on Protein: 286-318
Range on HMM: 296-328/328
Sequence Identity: 45% (15 aa)

IKDPNAVELLKRMLAIDPARRISAQNALKMPYF
...| |. ||..||..|| .||... ||  |||
NANPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase CDC2-S2_m.AA Pkinase_Tyr 35-172 26 4.4e-11 38.16 Pfam 5-155 (270) Show / Hide 
Range on Protein: 35-172
Range on HMM: 5-155/270
Sequence Identity: 26% (42 aa)

RLLGAGADGEVRVGFHR----KTGDKVAMKKM---YEHEY-LYDTIINESEILEEV-AHDNVVNLLGLTC-NNQG--TFMVMELMDG-SLRDVVSSR---
. ||.|| |||. |  .    .|. .|| |..   . ||  . .  ..| .|. .   |.|.|.|.|      .    ..|||.| . .|.|   ..   
KKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHRED

--KLGEHDIKAVMRQILEGLAWIHAHRIVHQDIKTSNVLVKRDGEKNKLVVKLADF
  .|  .|.    .|| .|... ......| |. . |.||..     ..||| .||
KQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE-----NNVVKICDF
Kinase CDC2-S2_m.AA CDK5 288-318 48 2.8e-10 28.2 In-house 257-287 (287) Show / Hide 
Range on Protein: 288-318
Range on HMM: 257-287/287
Sequence Identity: 48% (15 aa)

DPNAVELLKRMLAIDPARRISAQNALKMPYF
| .  .||..|| ..|. ||||..||. |||
DEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase CDC2-S2_m.AA CAMK 288-318 25 6.4e-07 17.57 In-house 395-425 (425) Show / Hide 
Range on Protein: 288-318
Range on HMM: 395-425/425
Sequence Identity: 25% (8 aa)

DPNAVELLKRMLAIDPARRISAQNALKMPYF
.. .  |...||  || .|.... .|. | .
SQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase CDC2-S2_m.AA STE 286-318 17 0.001443 8.61 In-house 303-359 (359) Show / Hide 
Range on Protein: 286-318
Range on HMM: 303-359/359
Sequence Identity: 17% (10 aa)

IKD----------------------PNAVELLKRMLAIDPARRISAQNALK--MPYF
..|                      |.  . ... | .||  | .|.  ||   | .
LPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI