Gene CDKB_c (S.moellendorffii)

CDKB_c

Species: S.moellendorffii
Alias: CDKB_c
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDKB

Sequence

Name Sequence Type Origin Length Description Download
CDKB_c.AA Protein None 328 None Fasta, JSON
CDKB_c.NA RNA None 987 None Fasta, JSON
CDKB_c.kin_dom Protein Kinase Domain None 317 None Fasta, JSON

Protein domain

Protein domains of CDKB_c.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CDKB_c.AA CDC2 4-320 50 4.5e-171 530.46 In-house 1-301 (301) Show / Hide 
Range on Protein: 4-320
Range on HMM: 1-301/301
Sequence Identity: 50% (169 aa)

YVKLEKVGEGTYGKVYKAREKNSGRLVALKKTRLEMEEEG--VPSTALREVSLLQMLSQSIYVVRLLCVEHVDKKGKPMLYLVFEFLDTDLKKYID-LFG
| |.||.||||||.|||.... ....||||| ||| |.||  |||||.|| |.|. | .   .|.|  | |        ||.|||.|| ||||| | ...
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-----NKLYMVFEYLDMDLKKYMDMSIP

RGNTGRPIPPKIIQVFVDSSGFVTGFLTSVICCQSFMYQLCKGVAHCHSHGVMHRDLKPQNLLVDKEKGILKIADLGLGRAFTVPLKSYT--HEIVTLWY
 .                          ...  .|.|||...||..||....|||||||||.|.|| || .|||| ||.|||..|.. ||  ||.|||||
KN-----------------------KHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDK-KGNIKIADFGLARAFGIPIRTYTTEHEVVTLWY

RAPEVLLGATHYSIPVDIWSVGCIFAEL---SRKVPLFPGDSELQQLLHIFRHEKKLLLGTPNDEIWPGVSKLRDWHE-FPQWKPQNISRAVPD------
||||.|||. .||.|||.||.||||||.     | |||.||||  ||  |||      |||||...||||..| |. . ||.||||..|. .|.      
RAPEILLGCKRYSTPVDMWSIGCIFAEMFMDVTKKPLFHGDSEIDQLFKIFR-----ILGTPNEQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKKKN

---LDPKGVDLLTKMLQYDPSKRISAKAAMQHPYF
   |||.|.||| .||||||.||||||.|.|||||
QSCLDPEGIDLLMQMLQYDPQKRISAKEALQHPYF
Kinase CDKB_c.AA CDK 4-320 44 2.6e-159 513.51 In-house 1-284 (284) Show / Hide 
Range on Protein: 4-320
Range on HMM: 1-284/284
Sequence Identity: 44% (155 aa)

YVKLEKVGEGTYGKVYKAREKNSG-----RLVALKKTRLEM-----EEEGVPSTALREVSLLQMLSQSIYVVRLLCVEHVDKKG-------KPMLYLVFE
| ||||.||||||.||||| |..|     ..||||| |.|      |.||.|.||.||.|||. |    ..|.|. | | ...        .  ||.|||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

FLDTDLKKYIDLFGRGNTGRPIPPKIIQVFVDSSGFVTGFLTSVICCQSFMYQLCKGVAHCHSHGVMHRDLKPQNLLVDKEKGI-----LKIADLGLGRA
..|.|||||.|                                   ....|.|| .|...|||...|||||||||.|... .|.     ||||| || ||
YMDHDLKKYMD-----------------------------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINN-NGEVKCGRLKIADFGLARA

FTV------PLKSYTHEIVTLWYRAPEVLLGATHYS--IPVDIWSVGCIFAELSR---KVPLFPGDSELQQLLHIFRHEKKLLLGTPNDEIWPGVSKLRD
| .      |.. ||||.|||||||||.|||..|||   |.|.|||||||||. .   . ||||||||. || .|||     ..|||....||||.|| |
FGIPHQMSEPNRTYTHEVVTLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFR-----ICGTPTEDNWPGVTKLPD

WHEFPQWKPQNISRAVPDLDPKGVDLLTKMLQYDPSKRISAKAAMQHPYF
.                       ||| |||.|||.|||||..|.|||||
Y-----------------------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase CDKB_c.AA CDK5 4-320 48 4.7e-148 471.2 In-house 1-287 (287) Show / Hide 
Range on Protein: 4-320
Range on HMM: 1-287/287
Sequence Identity: 48% (158 aa)

YVKLEKVGEGTYGKVYKAREKNSGRLVALKKTRLEMEEEGVPSTALREVSLLQMLSQSIYVVRLLCVEHVDKKGKPMLYLVFEFLDTDLKKYIDLFGRGN
| |.||.|||||| |||||.|... .||||. ||. | |||||||.||..||. | .   .|||  | | .||    | |||||.| |||||.| ..   
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKEL-KHKNIVRLHDVIHSEKK----LTLVFEFCDQDLKKYMDSCNG--

TGRPIPPKIIQVFVDSSGFVTGFLTSVICCQSFMYQLCKGVAHCHSHGVMHRDLKPQNLLVDKEKGILKIADLGLGRAFTVPLKSYTHEIVTLWYRAPEV
                         .   ..|||||| ||.| ||.| |.||||||||||. | .|.|| || || ||| .| . |.||.||||||.| |
-----------------------EMDMHIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINK-NGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDV

LLGATHYSIPVDIWSVGCIFAELS-RKVPLFPGDSELQQLLHIFRHEKKLLLGTPNDEIWPGVSKLRDWH----EFPQWKPQN-ISRAVPDLDPKGVDLL
|.|. ||| ..|.||.||||||..    ||||| ..  ||  ||.     ..|||. . ||...|| |.     ..| . ..   .  || || || |||
LMGSKHYSTSIDMWSCGCIFAEMANAGRPLFPGNDVEDQLKRIFK-----IMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLL

TKMLQYDPSKRISAKAAMQHPYF
 ||||..| .|||||||..||||
QKMLQCNPNQRISAKAALHHPYF
Kinase CDKB_c.AA CMGC 4-320 26 1.2e-133 441.97 In-house 1-513 (513) Show / Hide 
Range on Protein: 4-320
Range on HMM: 1-513/513
Sequence Identity: 26% (141 aa)

YVKLEKVGEGTYGKVYKARE--------------KNSGRLVALKKTRLE---------MEEEGVPSTALREVSLLQMLS----------------QSIYV
| ...|.||||||.|||.|               ......||.|| ...         .|..|.|..||||...|..|.                .  ..
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VRLLCVEHVDKKGKP-------------MLYLVFEFLDTDLKKYIDLFGRGNTG-RPIPPKIIQ--------VFVDSSGFVTGFLTSVICCQSFM-----
|.|. . . ..  ..              ||||||..|.||..||.   . . | ||.| .  .                    .     ...||     
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRP-----------P---HNIKYFMIHIRY

-YQLCKGVA--HCHSHG--VMHRDLKPQNLLVDKEK-------------------GILKIADLGLGRAFTVP---------------------LKSYTHE
 ||...|..  .||||.  ..||||||.|.|.....                   |.|||.| || |.. ..                     .. |||.
MYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHY

IVTLWYRAPEVLLGATHYS---------IPVDIWSVGCIFAELSRK--------VPLFPGDSE-----------LQQLLHIFRHEKKLLLGTPN------
.||.||||||.|||..||.          |.|.|||||||||. ..         |||||.||           . || .||.     .||||.      
VVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFK-----VLGTPTWMIQKG

---------DEIWPGVSKLRDWHE---------------------------FPQWKPQNISRAVPD----------------------------------
         .|.||...|| ...                            ||.|.|..... .|.                                  
KRHFNFCKHEEEWPNMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRK

-LDPKGVDLLTKMLQYDPSKRISAKAAMQHPYF
 .||...||| |||||||.|||.|. |.|||||
CCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase CDKB_c.AA Pkinase 4-320 29 3.5e-89 307.37 Pfam 1-293 (293) Show / Hide 
Range on Protein: 4-320
Range on HMM: 1-293/293
Sequence Identity: 29% (97 aa)

YVKLEKVGEGTYGKVYKAREKNSGRLVALKKTRLEMEEEGVPSTALR--EVSLLQMLSQSIYVVRLLCVEHVDKKGKPMLYLVFEFLDTDLKKYIDLF--
|....|.|.|..|.|||...|..|..||.|. ... |..... |..|  |......| .. ..|||... .     |. .|.|.|... .|.  .|||  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED----KDHIYMVMEYCEGGLY-VMDLFDY

--GRGNTGRPIPPKIIQVFVDSSGFVTGFLT--SVICCQSFMYQLCKGVAHCHSHGVMHRDLKPQNLLVDKEKGIL----KIADLGLGRAF-TVPLKSYT
  .                        .     |   |...|||...|...|||.|..||||||.|.|.| ..| .    ||.| || . | . .   .|
IST----------------------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MT

HEIVTLWYRAPEVLLGATHYSIPVDIWSVGCIFAELSRKVPLFPGD----SELQQLLHIFRHEKKLLLGTPNDEIWPGVSKLRDWHEFPQWKPQNISRAV
.  .|.||.||||..|...|. .||.||.|||..|.  . |.|||.    . . |.  |.|      .|.|... ||  .  .. . |..| ..  ..  
TFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICR-----IMGPPLHFDWPWWCSISYFF-FRHW-HF-HWTF-

PDLDPKGVDLLTKMLQYDPSKRISAKAAMQHPYF
. ... . |.....|..||.||..|. ..|||.|
HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase CDKB_c.AA CDK7 135-320 42 5.8e-89 237.0 In-house 106-288 (288) Show / Hide 
Range on Protein: 135-320
Range on HMM: 106-288/288
Sequence Identity: 42% (82 aa)

SFMYQLCKGVAHCHSHGVMHRDLKPQNLLVDKEKGILKIADLGLGRAFTVPLKSYTHEIVTLWYRAPEVLLGATHYSIPVDIWSVGCIFAELSRKVPLFP
..| .. .|. .|| . . |||||| |||.... |.||||| || |..  | . ||| .|| |||||| | || ||   ||.||||||||||   || .|
AYMMMTLQGLEYCHRNWILHRDLKPNNLLMNEN-GQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELMLRVPYLP

GDSELQQLLHIFRHEKKLLLGTPNDEIWPGVSKLRDWHEFPQWKP------QNISRAVPDLDPKGVDLLTKMLQYDPSKRISAKAAMQHPYF
|||.. ||  ||.      ||||..| ||..... |  .| .. .      ..|  | .|     .||. .|.  .|.||...  . ..|||
GDSDIDQLTRIFQ-----TLGTPTEEEWPNMCCMMDYIKFKDFPGYSRTPLRHIFTAASD---DLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase CDKB_c.AA S_TKc 4-320 29 1.3e-85 291.62 SMART 1-231 (231) Show / Hide 
Range on Protein: 4-320
Range on HMM: 1-231/231
Sequence Identity: 29% (96 aa)

YVKLEKVGEGTYGKVYKAREKNSGRLVALKKTRLEMEEEGVPSTALREVSLLQMLSQSIYVVRLLCVEHVDKKGKPMLYLVFEFLDT---DLKKYIDLFG
| .|.|.|.|..|||||.|.|..||.||.|. .          ...||...|..  .  ..|.|. | .        ||.|.|..|.   ||..||.  |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRG

RGNTGRPIPPKIIQVFVDSSGFVTGFLTSVICCQSFMYQLCKGVAHCHSHGVMHRDLKPQNLLVDKEKGILKIADLGLGRAFTVPLKSYTHEIVTLWYRA
|. ...|.|.  .                    ...|||.|.....|||||..||||||.|.|.|.    .||.| || | .       |. ..|.||.|
RHGLRFPFPE-HA--------------------RFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL-------TTFCGTPWYMA

PEVLLGATHYSI-PVDIWSVGCIFAELSRKVPLFPGDSELQQLLHIFRHEKKLLLGTPNDEIWPGVSKLRDWHEFPQWKPQNISRAVPDLDPKGVDLLTK
||||    .|.  ..|.||.|||..|.    |.||   ..|..... .                                          .| . |.. |
PEVL----GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG------------------------------------------SPEAKDFIRK

MLQYDPSKRISAKAAMQ-------HPYF
.||.||.||..|  |.|       ||.|
CLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CDKB_c.AA PITSLRE 135-320 47 2.3e-78 266.66 In-house 110-295 (295) Show / Hide 
Range on Protein: 135-320
Range on HMM: 110-295/295
Sequence Identity: 47% (91 aa)

SFMYQLCKGVAHCHSHGVMHRDLKPQNLLVDKEKGILKIADLGLGRAFTVPLKSYTHEIVTLWYRAPEVLLGATHYSIPVDIWSVGCIFAELSRKVPLFP
..| || .||.| |.. .||||||  |||    ||||||.| ||.| .  |.|.||  .|||||||||.|||.  || |||.|||||||||.  . |||.
CLMQQLLRGVEHMHDNWIMHRDLKTSNLLY-SHKGILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIFAEFITMKPLFQ

GDSELQQLLHIFRHEKKLLLGTPNDEIWPGVSKLRDWHEFP---QWKPQNISRAVP---DLDPKGVDLLTKMLQYDPSKRISAKAAMQHPYF
|.||. |.  ||      ..|||.  ||||...|  |  .    . .. |  . .|    .   | ||| .|| |.| .||.| .|..||.|
GKSEIDQINCIFK-----EMGTPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFPAENHISDTGFDLLNQMLTYNPKNRITASDALKHPWF
Kinase CDKB_c.AA PCTAIRE 136-320 47 1.6e-76 260.53 In-house 102-291 (291) Show / Hide 
Range on Protein: 136-320
Range on HMM: 102-291/291
Sequence Identity: 47% (94 aa)

FMYQLCKGVAHCHSHGVMHRDLKPQNLLVDKEKGILKIADLGLGRAFTVPLKSYTHEIVTLWYRAPEVLLGATHYSIPVDIWSVGCIFAELSRKVPLFPG
|..||  | | ||   ..||||||||||.. |.| || || || ||  || | | ||.|||||| |.||.| | || ..|.| |||||.|..   |||||
FLFQLLRGLAYCHRRKILHRDLKPQNLLIN-ERGELKLADFGLARAKSVPTKTYSHEVVTLWYRPPDVLMGSTDYSTQIDMWGVGCIFYEMCTGRPLFPG

DS------ELQQLLHIFRHEKKLLLGTPNDEIWPGVSKLRDWH--EFPQWKPQNISRAVPDLD---PKGVDLLTKMLQYDPSKRISAKAAMQHPYF
           ||  |||     .|||| .. ||||. . ..    ||....| .    | ||    .. ||||..||| . .|.|| .||.||||
STDSHYPGVKDQLHMIFR-----ILGTPDEKTWPGVKSNEEFRTYNFPRYREQPLINHAPRLDKILKQCQDLLTMLLQYESKNRVSAEKAMKHPYF
Kinase CDKB_c.AA PFTAIRE 136-320 48 2.6e-73 249.85 In-house 102-287 (287) Show / Hide 
Range on Protein: 136-320
Range on HMM: 102-287/287
Sequence Identity: 48% (93 aa)

FMYQLCKGVAHCHSHGVMHRDLKPQNLLVDKEKGILKIADLGLGRAFTVPLKSYTHEIVTLWYRAPEVLLGATHYSIPVDIWSVGCIFAELSRKVPLFPG
|..||  | . ||   |.||||||||||.  ..| || || || ||  || . | ||.|||||| | ||||.| ||  .|.| ||||| |.   .|.|||
FLFQLLRGLSYCHQRRVLHRDLKPQNLLI-SHCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTHLDMWGVGCIFVEMMWGQPAFPG

D-SELQQLLHIFRHEKKLLLGTPNDEIWPGVSKLRDW--HEFP--QWKPQNISRAVPDLD--PKGVDLLTKMLQYDPSKRISAKAAMQHPYF
    . ||  ||.     .||||... ||||..|  .  | |.    ||..  ...| ..  |.. ||..||||. | .|.||..|||||||
MKDITDQLEKIFK-----VLGTPTEDTWPGVCHLPNYKPHWFRGRFYKPKKLCHQWPRIYYIPHAEDLMMKMLQCEPRDRVSAQEAMQHPYF
Kinase CDKB_c.AA CDK4 134-320 47 7.3e-67 228.4 In-house 113-290 (290) Show / Hide 
Range on Protein: 134-320
Range on HMM: 113-290/290
Sequence Identity: 47% (89 aa)

QSFMYQLCKGVAHCHSHGVMHRDLKPQNLLVDKEKGILKIADLGLGRAFTVPLKSYTHEIVTLWYRAPEVLLGATHYSIPVDIWSVGCIFAELSRKVPLF
.  | ||  ||   ||| . ||||||||.||  . | .|.|| || | .    .  |  .|||||||||||| .. |  |||.|||||||||. .  |||
KHMMHQLLRGVDFLHSHRIIHRDLKPQNILVTSD-GHVKLADFGLARIYSFQMA-LTPVVVTLWYRAPEVLLQSY-YNTPVDMWSVGCIFAEMYCRRPLF

PGDSELQQLLHIFRHEKKLLLGTPNDEIWPGVSKLRDWHEFPQWKPQNISRAVPDLDPKGVDLLTKMLQYDPSKRISAKAAMQHPYF
.| ||  ||  ||      . |.|  . ||  . |  |  ||| .|...   .|...  | ||| ||| |...||.|| .. |||||
CGQSEKDQLHKIFD-----VMGLPPEDDWPRDVSL-PWDHFPQRHPRPFKDFCPHMCKQGDDLLQKMLCYNHHKRMSAYQCLQHPYF
Kinase CDKB_c.AA CRK7 133-320 32 1.7e-58 200.3 In-house 114-343 (343) Show / Hide 
Range on Protein: 133-320
Range on HMM: 114-343/343
Sequence Identity: 32% (77 aa)

CQSFMYQLCKGVAHCHSHGVMHRDLKPQNLLVDKEKGILKIADLGLGRAFTVPL--KSYTHEIVTLWYRAPEVLLGATHY--------------------
| .|| ||  |.. ||  ...|||.|  |.|..  .|..||||.|| | .      . ||  ..|||||.|| |||...|                    
CKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMN-NQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHILKELIRNIKSIQLSL

------------------SIPVDIWSVGCIFAELSRKVPLFPGDSELQQLLHIFRHEKKLLLGTPNDEIWPGVSKLRDWHEFPQWKPQN--ISRAVPDLD
                     .|.||.|||..||  | |.|.|  |..||  |..     . |.|| . || | ||  |. .   ||.    .| . .  
LISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYK-----ICGSPNPNNWPEVMKLPWWNTM---KPKRQYNRRLREEFY

---------PKGVDLLTKMLQYDPSKRISAKAAMQHPYF
         .. .||| ||| .||.||..|. . ||..|
HHKKPVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase CDKB_c.AA CDK4 4-97 38 3.6e-27 90.11 In-house 1-100 (290) Show / Hide 
Range on Protein: 4-97
Range on HMM: 1-100/290
Sequence Identity: 38% (38 aa)

YVKLEKVGEGTYGKVYKAREKNSGRLVALKKTRLEMEEE--GVPSTALREVSLLQMLSQSIY--VVRLLCVEHVDKKGK--PMLYLVFEFLDTDLKKYID
|...  .||| ||.||.||   .|. ||||. |  ..||  |.|   .||.|..  | |.    .|.|. | ||   .    .. .|||  | ||. |.|
YQCVAEIGEGAYGTVYRARDLHTGHFVALKQVRIPIGEEGGGMPMSTIREISVMRHLCQFEHPNIVKLMDVCHVMDTDRAEMKITMVFEHCDWDLHTYLD
Kinase CDKB_c.AA PCTAIRE 4-97 52 2.2e-26 90.18 In-house 1-88 (291) Show / Hide 
Range on Protein: 4-97
Range on HMM: 1-88/291
Sequence Identity: 52% (49 aa)

YVKLEKVGEGTYGKVYKAREKNSGRLVALKKTRLEMEEEGVPSTALREVSLLQMLSQSIYVVRLLCVEHVDKKGKPMLYLVFEFLDTDLKKYID
|.||.| |||||  ||| | |  . |||||  |||  ||| | || ||||||. | .   .| |  . | ..     | ||||..| |||.|.|
YIKLDKLGEGTYATVYKCRSKLTDNLVALKEIRLEH-EEGAPCTAIREVSLLKDL-KHANIVTLHDIIHTHH----QLTLVFEYMDMDLKQYMD
Kinase CDKB_c.AA PFTAIRE 4-97 44 2.9e-26 89.48 In-house 1-88 (287) Show / Hide 
Range on Protein: 4-97
Range on HMM: 1-88/287
Sequence Identity: 44% (42 aa)

YVKLEKVGEGTYGKVYKAREKNSGRLVALKKTRLEMEEEGVPSTALREVSLLQMLSQSIYVVRLLCVEHVDKKGKPMLYLVFEFLDTDLKKYID
|.|||| |||.| .|||.. .  ...||||  ||. .|||.| || ||.|||. |  .  .| |  . | ..     | .|||...|||..|.|
YEKLEKLGEGSYATVYKGISCINQQFVALKEIRLQ-QEEGTPFTAIREASLLKNLKHA-NIVCLHDIIHTKE----TLTFVFEYVHTDLCQYMD
Kinase CDKB_c.AA CRK7 4-92 40 2.9e-26 87.41 In-house 1-97 (343) Show / Hide 
Range on Protein: 4-92
Range on HMM: 1-97/343
Sequence Identity: 40% (39 aa)

YVKLEKVGEGTYGKVYKAREKNSGRLVALKKTRLEME---EEGVPSTALREVSLLQMLS-QSIYVVRLLCVE---HVDKKGKP-MLYLVFEFLDTDL
| ... .||||||.||||. |. | .||||| |.. |   .|| | || ||. .|. |  |.|   .   ..    ...| .    |.|||  | ||
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDL
Kinase CDKB_c.AA CDK7 4-96 36 3.7e-24 60.85 In-house 1-92 (288) Show / Hide 
Range on Protein: 4-96
Range on HMM: 1-92/288
Sequence Identity: 36% (35 aa)

YVKLEKVGEGTYGKVYKAREKNSGRLVALKKTR-LEMEEE---GVPSTALREVSLLQMLSQSIYVVRLLCVEHVDKKGKPMLYLVFEFLDTDLKKYI
| |....|||... ||||.....|. || || . |   .|   |.  ||.||. .|| . |   |. |. .       |  ..|||.|.|.||   |
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEM-QHDNVIGLIDIFMH----KSNIQLVFDFMDWDLEVVI
Kinase CDKB_c.AA PITSLRE 4-55 43 1.4e-19 68.06 In-house 1-55 (295) Show / Hide 
Range on Protein: 4-55
Range on HMM: 1-55/295
Sequence Identity: 43% (24 aa)

YVKLEKVGEGTYGKVYKAREKNSGRLVALKKTRLE--MEEEGVPSTALREVS-LL
...| ...||||| ||.|..|  .. ||||.. .|   | || | |.|||.. .|
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMIL
Kinase CDKB_c.AA TyrKc 4-320 18 2.7e-11 -40.05 SMART 1-280 (280) Show / Hide 
Range on Protein: 4-320
Range on HMM: 1-280/280
Sequence Identity: 18% (64 aa)

YVKLEKVGEGTYGKVYKAREKNSGRLVALKKTRLEMEEEGVPSTALREVSLLQML-SQSIYVVRLLCVEHVDKKGK---PMLYLVFEFLDT-DLKKYI-D
 ....| ||| .|.|||.. |   . || |. . .          .|| ... .|  .   .|||. |   ..      . |..|.|. .  |||.|. .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

LFGRGNTGRPIPPKIIQVFVDSSGFVTGFLTSVICCQSFMYQLCKGVAHCHSHGVMHRDLKPQNLLVDKEKGILKIADLGLGRAFTVP------LKSYT-
  ..                           ..    ||..| ..| .. ||... ||||   | ||.... . ||.| || |. .         . |. 
HRPK--------------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRK

----HEI--VTLWYRAPEVLLGATH-YSIPVDIWSVGCIFAEL-SRKVPLFPGD----SELQQLLHIFRHEKKLLLGTPNDEIWPGVSKLRDWHEFPQWK
    ..   . .   |||..   .. ...  |.|| |    |. ..  .  ||.     . |....  .. . .     .    | .|            
KEHKGGKTMLPIRWMAPECI--NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY---P-MS------------

PQNISRAVPDLDPKGVDLLTKMLQYDPSKRISAKAAMQHPYF
    .   .   ..  .. ..  ..||..| . ..   | .|
----F---VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase CDKB_c.AA Pkinase_Tyr 4-34 37 0.000245 15.31 Pfam 1-35 (270) Show / Hide 
Range on Protein: 4-34
Range on HMM: 1-35/270
Sequence Identity: 37% (13 aa)

YVKLEKVGEGTYGKVYKAREK----NSGRLVALKK
 ....| ||| .|.|||.. |    | .  || |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKM
Kinase CDKB_c.AA Pkinase_Tyr 135-178 36 0.001221 12.95 Pfam 115-157 (270) Show / Hide 
Range on Protein: 135-178
Range on HMM: 115-157/270
Sequence Identity: 36% (16 aa)

SFMYQLCKGVAHCHSHGVMHRDLKPQNLLVDKEKGILKIADLGL
.. .| .|| .. .|..  ||||   | ||.... . ||.| ||
QMCWQIAKGMEYLESKNCIHRDLAARNCLVTENN-VVKICDFGL