Gene CLK_b (S.moellendorffii)

CLK_b

Species: S.moellendorffii
Alias: CLK_b
External Links:
Annotation:

Classification

Group: CMGC
Family: CLK

Sequence

Name Sequence Type Origin Length Description Download
CLK_b.AA Protein None 342 None Fasta, JSON
CLK_b.NA RNA None 1029 None Fasta, JSON
CLK_b.kin_dom Protein Kinase Domain None 315 None Fasta, JSON

Protein domain

Protein domains of CLK_b.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CLK_b.AA CLK 23-338 42 6.00000000001e-150 453.21 In-house 27-350 (350) Show / Hide 
Range on Protein: 23-338
Range on HMM: 27-350/350
Sequence Identity: 42% (144 aa)

FVAIKVIRNVPKYREATLIEID-VLKALQKH-DKNGKRG--CLQMKEWFDY-RNHVCIVSEKLGPSLYDFLKKNS------YRPFSIEHV---GWQLLNS
.||.|.|||| |||||  .||. ..|....  |.|.|.   |..| .||||  .|.||| |..| |.|||.|.|.      |.|. |.|.   ..||...
YVALKIIRNVEKYREAAWVEINQIMKKINEKHDPNNKYWEHCWKMNDWFDYGHGHICIVFELYGLSIYDFMKSNNSKMPNKYIPYPIDHIRHMAYQLCEA

VAYLHELSLIHTDLKPENILLVSS---AYVKTLDYKVVHFVRSFLVILTLFPLQSARLDKHLTRTPTSAEIRLIDFGSAT---FENQHHSSIVSTRQYRA
|  ||...|.|||||||||..|.|       |. |...  .            .|    .   ... . .|..|||||||   |.. ||| |||||.|||
VKFLHDMKLTHTDLKPENICFVDSRFTHFDCTFKYNHKKKIN----------KKS-NNCVCHYWHVKNTHICVIDFGSATKIRFDHEHHSTIVSTRHYRA

PEIILGLGWSYACDLWSVGCILVELFSGDPLFQTHENLEHLAMMERILG-PIPRRIIDNVD--RKAQKYFKNGRELNWPDAASSLESIRTVKRLPRLKEL
||.|||||||. || ||.||||.|| .|. |||||.|.|||||||||.| ||| . |   .  .  ||||...|... .. ...  ... .| | .... 
PEVILGLGWSQPCDVWSIGCILFELYTGFTLFQTHDNREHLAMMERIMGMPIPQWMIQRTRRFKVKQKYFYHNRLDWDWHNSDGRYVMENCKPLKQYMD-

VQLHVEHSASSLTDLLEGLLRYGASDRLTAKEALRHPFF
 . . ||   .| ||.. .| |  | |.|.|.|| ||||
-CKDPEH--RQLFDLIRKMLEYDPSKRITCKDALQHPFF
Kinase CLK_b.AA CMGC 15-338 18 1.3e-86 284.57 In-house 24-513 (513) Show / Hide 
Range on Protein: 15-338
Range on HMM: 24-513/513
Sequence Identity: 18% (97 aa)

NQS--------RKYQEFVAIKVIRNVPKYREA-------------TLIEIDVLKALQ-KHDKNG---------KRG--CLQMKEWFDYRN----------
||         ....|.|||| |.|.. | |              .| ||  || |. .||. .         |    .......| ..|          
NQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDP-NWQRRDDPDNKHHNNIVKLYDIFYHKNSDGNEYEDKH

-------HVCIVSEKLGPSLYDFLKKNS--YRP-----FSIEH---------------VG------WQLLNSVA--YLHELS--LIHTDLKPENILLVSS
       |...| | .. .||...|.|.  |..     .|  |                       .|.|....  |.|      ||.||||||||. . 
IISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHN

AYV-------KTLDYKVVHFVRSFLVILTLFPLQSARLDKHLTRTPTSAE----------IRLIDFGSATFENQH------------------------H
  .       .                                      |          ....|||.|.....|                        .
CELITRMMWKS--------------------------------------EDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPY

SSIVSTRQYRAPEIILGLG----------WSYACDLWSVGCILVELFSG--------DPLFQTHEN-----------LEHLAMMERILGPIPRRIIDN--
.. |.|| ||||||.|| .          .....| ||||||. |.. |        .|||..| .           ...|... ..||... ..|..  
THYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPT-WMIQKGK

----VDRKAQKYFKNGRELNW----------------PDAASSLESI---RTVKRLPRLKELVQLHVE-------------------------------H
     ... .....    ...                .. |    ..      .. . .|.|.  | .                               .
RHFNFCKHEEEWPNMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKC

SASSLTDLLEGLLRYGASDRLTAKEALRHPFF
  . . |||...|.|  ..|.||..||.||.|
CDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase CLK_b.AA Pkinase 18-338 19 1.2e-56 199.29 Pfam 21-293 (293) Show / Hide 
Range on Protein: 18-338
Range on HMM: 21-293/293
Sequence Identity: 19% (68 aa)

RKYQEFVAIKVIRNVPKYREATLI------EIDVLKALQKHDKNGKRGCLQMKEWFDYRNHVCIVSEKLGP-----SLYDFLK---KNSY--RPFSIEHV
..... ||.|.|. . . ..  ..      || ..| | .|.       .....|| ...|...| | ..      .|.|...   ....   .  . ..
KGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRL-NHPN-----IVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFY

GWQLLNSVAYLHELSLIHTDLKPENILLVSSAYVKTLDYKVVHFVRSFLVILTLFPLQSARLDKHLTRTPTSAEIRLIDFGSA----TFENQHHSSIVST
 .|.|  ..|.|. . || ||||||||...  ....                                      ....|||.|    .  |.  .... |
MYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA-------------------------------------CVKICDFGLAKQFDY-NNS-MTTFCGT

RQYRAPEIIL-GLGWSYACDLWSVGCILVELFSGDPLFQTH----ENLEHLAMMERILGPIPRRIIDNVDRKA-----QKYFKNGRELNWPDAASSLESI
. |.|||.|. | ......| ||.|||| |...| |.|. |    . .....|..||.||.... ... ...      . . .                 
PWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRH-W-H-----------------

RTVKRLPRLKELVQLHVEHSASSLTDLLEGLLRYGASDRLTAKEALRHPFF
          .  ..      ... |.....|..  ..|.||...| ||.|
----------F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
S_TKc CLK_b.AA S_TKc 6-338 19 1.9e-47 164.88 SMART 1-231 (231) Show / Hide 
Range on Protein: 6-338
Range on HMM: 1-231/231
Sequence Identity: 19% (71 aa)

KSIESNL------VVNQSRKYQ--EFVAIKVIRNVPKYREATLIEIDVLKALQKHDKNGKRGCLQMKEWFDYRNHVCIVSEKLGP---SLYDFLKKNS--
  |   .      .| . |.    . ||||.|.      | .. ||..||        .     .....|.  .|...| | ..    .|.|..||.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----YRPFSIEHVGWQLLNSVAYLHELSLIHTDLKPENILLVSSAYVKTLDYKVVHFVRSFLVILTLFPLQSARLDKHLTRTPTSAEIRLIDFGSATFE
     . .  . .. .|... ..|.|..  || ||||||||| .                                           .| ..|||.|.. 
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------------------------------------------HIKICDFGLARQL

NQHHSSIVSTRQYRAPEIILGLGWSY-ACDLWSVGCILVELFSGDPLFQTHENLEHLAMMERILGPIPRRIIDNVDRKAQKYFKNGRELNWPDAASSLES
    .... |. |.|||..   |... .|| ||.|||| |...| |.|.     .. .|...|.                                    
----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP-----QMQMMFKKIG------------------------------------

IRTVKRLPRLKELVQLHVEHSASSLTDLLEGLLRYGASDRLTAKEALR-------HPFF
                      ... |.....|..  ..|.|| |||.       ||.|
---------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CLK_b.AA DYRK 171-338 30 3.5e-41 143.15 In-house 140-320 (320) Show / Hide 
Range on Protein: 171-338
Range on HMM: 140-320/320
Sequence Identity: 30% (57 aa)

P-TSAEIRLIDFGSATFENQHHSSIVSTRQYRAPEIILGLGWSYACDLWSVGCILVELFSGDPLFQTHENLEHLAMMERILGPIPRRIIDNV-DRKAQKY
|    .| .|||||..||.|. .. .  | |||||.|||.  .|| | ||.||||.||| | |||.   . . ||..  .||..|. .||.   |...|.
PRNKSTIKVIDFGSSCFEHQRIYTYIQSRFYRAPEVILGCPYCYAIDMWSLGCILAELFTGWPLFPGENEYDQLACIMEVLGMPPKWMIDKGRCRRKHKF

FKNGRELNWPDAASSLESIR------TVKRLPRLKELVQLHVEHS---------ASSLTDLLEGLLRYGASDRLTAKEALRHPFF
|..   . .    .. ....      |.|. | ..  . .  ...          . ..|.....| .  . |.|...||.||.|
FDC---FMYCECDEWTKQNKITDHYMTPKCHPTKR-GQRRPPGRRNWDPRHQCDDHQFKDFIKKCLQWDPHKRITPSQALQHPWF
Kinase CLK_b.AA DYRK 18-131 42 3.1e-38 133.36 In-house 21-139 (320) Show / Hide 
Range on Protein: 18-131
Range on HMM: 21-139/320
Sequence Identity: 42% (50 aa)

RKYQEFVAIKVIRNVPKYREATLIEIDVLKALQKHDKNGKRGCLQMKEWFDYRNHVCIVSEKLGPSLYDFLKKNSYRPF-SIEHV---GWQLLNSVAYLH
.| .| ||||.||| ...   ..|||  |. | ..|.. |  |..|.. | .|||.||| | |  .||.|||.|. ..| |...|   . |.|..  .||
HKTNEMVAIKIIRNNKRFHRQAQIEIKILEYLNQQDPDDKYHCVHMYDYFYHRNHLCIVFELLSMNLYEFLKNNHFQGFFSLNLVRKFAQQILTCLKFLH

EL-SLIHTDLKPENILLVS
.. ..|| |||||||.|..
KNENIIHCDLKPENIMLKQ
Kinase CLK_b.AA DYRK2 19-129 39 3.1e-38 121.73 In-house 22-135 (318) Show / Hide 
Range on Protein: 19-129
Range on HMM: 22-135/318
Sequence Identity: 39% (45 aa)

KYQEFVAIKVIRNVPKYREATLIEIDVLKALQKHDKNGKRGCLQMKEWFDYRNHVCIVSEKLGPSLYDFLKKNSYRPFSIEHV---GWQLLNSVAYLHEL
|....||||.|||  .. . ...|| .|... ..||..   |  |.. | .|||.||. | |. .||...|||..  || . |   . ..|..   ||. 
KTKQHVAIKMIRNKKRFHNQAYEEIRILHHIRRQDKDNTMNCVHMLDYFYFRNHHCITFELLSMNLYEYIKKNHFQGFSLQLVRRFAHSILQCLRFLHKN

SLIHTDLKPENILL
 .|| |||||||||
NIIHCDLKPENILL
Kinase CLK_b.AA DYRK2 169-338 26 7.9e-31 97.22 In-house 136-318 (318) Show / Hide 
Range on Protein: 169-338
Range on HMM: 136-318/318
Sequence Identity: 26% (50 aa)

RTPTSAEIRLIDFGSATFENQ-HHSSIVSTRQYRAPEIILGLGWSYACDLWSVGCILVELFSGDPLFQTHENLEHLAMMERILGPIPRRIIDNV----DR
. ..   | .||||| .||.| .    . .| |||||.|||.  . | |.|| |||..||..| |||      . .|.|  .||  |. ..|.      .
KQWNRSGIKVIDFGSSCFEHQYRIYTYIQSRFYRAPEVILGGKYGMAIDMWSFGCIMAELYTGYPLFPGENENDQFACMMEVLGMPPKKFFDTWFYIHCF

KAQKYFK-------NGRELNWPDAASSLESIRT----VKRLPRLKELVQLHVEHSASSLTDLLEGLLRYGASDRLTAKEALRHPFF
... .|.       .      .|    .. ...     .| |  |....   .    ...| .   .   .| |.|...||.||..
RRKYFFNSHCFEWYC---TFMTDHSMEIPKHYKNRHGKRRPPGSKSWKSVLKGCEDENFIDFIKRCFEWDPSERMTPSQALKHPWI
Kinase CLK_b.AA HIPK 18-130 39 1.1e-24 74.24 In-house 21-135 (329) Show / Hide 
Range on Protein: 18-130
Range on HMM: 21-135/329
Sequence Identity: 39% (46 aa)

RKYQEFVAIKVIRNVPKYREATLIEIDVLKALQKHDKNGKRGCLQMKEWFDYRNHVCIVSEKLGPSLYDFLKKNSYRPFSIEH---VGWQLLNSVAYLHE
|  .| ||||...| | |     ||. .|. |.. . .     . . | |. .||.|.| | |   ||||.|.| . |  . |   .  | |   . | |
RGTNEMVAIKILKNHPYYARQGQIEVSILHCLSQENADEYH-FVRAYECFHHKNHTCLVFEMLEQNLYDFQKQNKFMPLPLKHIRPILQQVLTALMKLKE

LSLIHTDLKPENILLV
|.||| |||||||.||
LGLIHADLKPENIMLV
Kinase CLK_b.AA DyrkP 174-254 46 1.9e-24 76.82 In-house 145-225 (323) Show / Hide 
Range on Protein: 174-254
Range on HMM: 145-225/323
Sequence Identity: 46% (38 aa)

AEIRLIDFGSATFENQHHSSIVSTRQYRAPEIILGLGWSYACDLWSVGCILVELFSGDPLFQTHENLEHLAMMERILGPIP
.....|||||. |   | || |  | |||||.|.|  . |  |.||.|||| ||. |  |||  .    || .  |.||.|
CQVKIIDFGSSCFIHDHLSSYVQSRSYRAPEVIIGCKYDYRIDMWSLGCILAELWTGNVLFQNDNIQGLLARVIGIIGPFP
Kinase CLK_b.AA DYRK1 21-130 40 2.5e-23 78.42 In-house 24-138 (321) Show / Hide 
Range on Protein: 21-130
Range on HMM: 24-138/321
Sequence Identity: 40% (46 aa)

QEFVAIKVIRNVPKYREATLIEIDVLKALQKHDKNGKRGCLQMKEWFDYRNHVCIVSEKLGPSLYDFLKKNSYRPFS---IEHVGWQLLNSVAYLH--EL
||.||||.|.|   . .  .||| .|  . ||||. |   ...|. | .|||.|.| | |   ||| |.  ..|  |   .     |.. .. ..   ||
QEYVAIKIIKNKKPFYNQAQIEIRLLELMNKHDKEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKFAQQMCTALLFMSTPEL

SLIHTDLKPENILLV
..|| |||||||||.
DIIHCDLKPENILLC
Kinase CLK_b.AA DYRK1 167-277 36 3.9e-22 74.14 In-house 136-245 (321) Show / Hide 
Range on Protein: 167-277
Range on HMM: 136-245/321
Sequence Identity: 36% (41 aa)

LTRTPTSAEIRLIDFGSATFENQHHSSIVSTRQYRAPEIILGLGWSYACDLWSVGCILVELFSGDPLFQTHENLEHLAMMERILGPIPRRIIDNVDRKAQ
| . |  . |..|||||.   .|     .  | ||.||..||. .. | |.||.||||||.  |.|||   . .. .  .  .||  |...||    ||.
LLCNPKRSAIKIIDFGSSCQLGQRIYQYIQSRFYRSPEVLLGIEYDMAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNKIVEVLGMPPKHMIDQAP-KAH

KYFKNGRELNW
|||.   .  |
KYFEKDPDNTW
Kinase CLK_b.AA YAK 22-129 40 4.4e-22 71.47 In-house 25-139 (347) Show / Hide 
Range on Protein: 22-129
Range on HMM: 25-139/347
Sequence Identity: 40% (46 aa)

EFVAIKVIRNVPKYREATLIEIDVLKAL-QKHDKNGKR---GCLQMKEWFDYRNHVCIVSEKLGPSLYDFLKKNSYRPFS---IEHVGWQLLNSVAYLHE
| .|.||| | . |      || .|. | |.|| |.|      | |   | ..|| |.| | |  .||..|| | .. ||   |     | | .   | .
ELFAVKVIKNRQAYFQQAKNEIQILRVLNQQHDPNNKNYQKHILRMYDFFVHKNHFCLVFEMLSNNLYEYLKQNKFCGFSFQLIRQWTKQILDGMCVLEN

LSLIHTDLKPENILL
  .|| |||||||.|
KQIIHCDLKPENIML
Kinase CLK_b.AA SRPK 19-143 28 4.5e-22 52.21 In-house 22-178 (554) Show / Hide 
Range on Protein: 19-143
Range on HMM: 22-178/554
Sequence Identity: 28% (45 aa)

KYQEFVAIKVIRNVPKYREATLIEIDVLKALQKHDKN-----------------------GKRGCLQMKEWFDYR----NHVCIVSEKLGPSLYDFLKKN
.|  .||.|. .  | | |. . ||  |... |||.|                       ..  ..|.   |  |    ||.| | | ||..|..  |..
QYDRYVAMKIVKSAPHYTETAVDEIKLLQCVRKHDPNPQWMHFLKEYYEDYKRDCKEFDPNRCHVVQLLDHFKHRGPNGNHYCMVFEVLGHNLLKWIKHY

SYRPFSIEHV---GWQLLNSVAYLHEL-SLIHTDLKPENILLVSS-AYVKTLDYKVV
 |.   .. |     |.|    |||.  . ||||.||||.||  . .|.| ......
NYQGMPMHCVKQIARQVLIGLDYLHRKCGIIHTDIKPENVLLCVNQDYIKRMAAEWT
Kinase CLK_b.AA SRPK 197-258 38 1.8e-19 45.34 In-house 415-482 (554) Show / Hide 
Range on Protein: 197-258
Range on HMM: 415-482/554
Sequence Identity: 38% (26 aa)

TRQYRAPEIILGLGWSYACDLWSVGCILVELFSGDPLFQTHE------NLEHLAMMERILGPIPRRII
|||||.|| |.| |...  | ||. | . ||  || || .|.      . .|.| ..  .| ||. ..
TRQYRSPEVIIGAGYNTPADIWSTACMAFELATGDYLFEPHSGEDYSRDDDHIAHIIELCGKIPWHFA
Kinase CLK_b.AA YAK 171-234 43 4e-17 54.35 In-house 142-205 (347) Show / Hide 
Range on Protein: 171-234
Range on HMM: 142-205/347
Sequence Identity: 43% (28 aa)

PTSAEIRLIDFGSATFENQHHSSIVSTRQYRAPEIILGLGWSYACDLWSVGCILVELFSGDPLF
| . ||..|||||.  | .     .  | ||.||||..   . . | || |||..||| | |.|
PNKPEIKIIDFGSSCQEKKMVYTYIQQRHYRSPEIIVWMIYCTSIDMWSLGCIVAELFLGLPIF
Kinase CLK_b.AA PRP4 15-128 32 1.6e-15 53.39 In-house 19-138 (320) Show / Hide 
Range on Protein: 15-128
Range on HMM: 19-138/320
Sequence Identity: 32% (40 aa)

NQSRKYQEFVAIKVIRNVPKYREATLIEIDVLKALQKH--DKNGKRGCLQMKEWFDYRNHVCIVSEKLGPSLYDFLKKNSY---RPFSIEHV---GWQLL
..  . .| ||||.||| .  .   | |. .|. |     ||| |  |..|.. | .|.| |.| | .  .| . |||  |     .... |     ||.
RDQTRGNEMVAIKIIRNNEIMHKTGLRELEILQKLNDAPTDKNDKFHCVRMFRHFNHRQHMCLVFECMSMNLREVLKK--YGKDVGLHLKAVRSYAQQLF

NSVAYLHELSLIHTDLKPENIL
     |  .  .| |.|| |||
LALKHLKKCNILHADIKPDNIL
Kinase CLK_b.AA PRP4 176-234 49 1.5e-12 42.34 In-house 146-205 (320) Show / Hide 
Range on Protein: 176-234
Range on HMM: 146-205/320
Sequence Identity: 49% (30 aa)

IRLIDFGSATF--ENQHHSSIVSTRQYRAPEIILGLGWSYACDLWSVGCILVELFSGDPLF
. ..|||||    ||      || | |||||||.|    |. |.||||| | ||. |  .|
LKMCDFGSASHIHENEITPYLVS-RFYRAPEIIIGHPYDYQIDMWSVGCTLYELYTGKIMF
Kinase CLK_b.AA HIPK 176-234 46 8.1e-12 33.0 In-house 144-203 (329) Show / Hide 
Range on Protein: 176-234
Range on HMM: 144-203/329
Sequence Identity: 46% (28 aa)

IRLIDFGSATFENQH-HSSIVSTRQYRAPEIILGLGWSYACDLWSVGCILVELFSGDPLF
.. ||||||    .   .  .  | ||||||||||    . | || ||.. ||| | ||.
VKVIDFGSASHVSKVVCNTYLQSRYYRAPEIILGLPFCENHDMWSLGCVIAELFLGWPLY
Kinase CLK_b.AA DyrkP 26-131 32 1.2e-09 27.24 In-house 29-141 (323) Show / Hide 
Range on Protein: 26-131
Range on HMM: 29-141/323
Sequence Identity: 32% (37 aa)

IKVIRNVPKYREATLIEIDVLKALQKHDKNGKRGCLQMKEWFDYRNHVCIVSEKLGPSLYDFLKKN----SYRPFSI---EHVGWQLLNSVAYLHELSLI
.|.| |   | .  . || .|. .        .  |.. ..|  . |. |. | |   ||.| | |      | | .     .  |.| .. |.| | ||
MKIIENNKDYFDQSIDEIKLLRYINYNGDVDEKNVLRYYDYFYHKEHLFIITELLKDNLYEFYKFNRENEQQRYFTVGRLQKITQQILIALDYIHSLRLI

HTDLKPENILLVS
| ||||||||. |
HCDLKPENILMKS
TyrKc CLK_b.AA TyrKc 8-338 14 1.7e-05 -133.97 SMART 1-280 (280) Show / Hide 
Range on Protein: 8-338
Range on HMM: 1-280/280
Sequence Identity: 14% (56 aa)

IESNLV--------VNQSRKYQEFVAIKVIRNVPKYREATLIEIDVLKAL-QKHDK--NGKRGCLQMKEWFDYRNHVCIVSE--KLGPSLYDFLKKNSYR
|. . .        | . . . . ||.|....    ||. . |. ... |  .|.   .    |.| .. | |   ..|| |  ..| .| |.|.|.  .
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHG-DLKDYLRKHRPK

PFSIE---HVGWQLLNSVAYLHELSLIHTDLKPENILLVSSAYVKTLDYKVVHFVRSFLVILTLFPLQSARLDKHLTRTPTSAEIRLIDFGSATFENQH-
 .. .   .  ||  .  .|||.  .|| ||   |.|. .                                            ..  ||| . .   . 
-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----------------------------------------TVKISDFGLSRDIYDDD

-----HSSIVSTR--QYR--------APEIILGLGWSYACDLWSVGCILVELFS-------G-----DPLFQTHENLEHLAMMERILG--PIPRRIIDNV
     .. ....   . .        ||| |     . . | || |  . |.|.       |      . .. .|....  .|..     |.        
QQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-------

DRKAQKYFKNGRELNWPDAASSLESIRTVKRLPRLKELVQLHVEHSASSLTDLLEGLLRYGASDRLTAKEALRHPFF
                                            .  . . .. .   .. ..|| | .|   | .|
------------------------------------------FVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase CLK_b.AA PRP4 311-338 42 1.7e-05 16.15 In-house 293-320 (320) Show / Hide 
Range on Protein: 311-338
Range on HMM: 293-320/320
Sequence Identity: 42% (12 aa)

LTDLLEGLLRYGASDRLTAKEALRHPFF
. |||...|    . | |  |||.|||.
FKDLLDKCLMLDPKKRITCNEALKHPFI
Kinase CLK_b.AA SRPK 324-338 53 0.0001 6.46 In-house 540-554 (554) Show / Hide 
Range on Protein: 324-338
Range on HMM: 540-554/554
Sequence Identity: 53% (8 aa)

SDRLTAKEALRHPFF
..| ||||.|.||. 
EKRATAKECLQHPWL
Kinase CLK_b.AA DYRK1 303-338 33 0.000161 11.23 In-house 286-321 (321) Show / Hide 
Range on Protein: 303-338
Range on HMM: 286-321/321
Sequence Identity: 33% (12 aa)

HVEHSASSLTDLLEGLLRYGASDRLTAKEALRHPFF
|  .  .   ||.. .|.|    |.|  .||.|.||
HSVEDYLKFKDLIKRMLQYDPKQRITPYYALQHSFF
Kinase CLK_b.AA DyrkP 313-338 46 0.000228 9.54 In-house 298-323 (323) Show / Hide 
Range on Protein: 313-338
Range on HMM: 298-323/323
Sequence Identity: 46% (12 aa)

DLLEGLLRYGASDRLTAKEALRHPFF
|    .|      | ||||||.||.|
DFVRQCLQIDFTRRPTAKEALQHPWF
Kinase CLK_b.AA YAK 311-338 28 0.000344 9.7 In-house 320-347 (347) Show / Hide 
Range on Protein: 311-338
Range on HMM: 320-347/347
Sequence Identity: 28% (8 aa)

LTDLLEGLLRYGASDRLTAKEALRHPFF
..|.. .||      | ..  |  ||| 
FIDFINQLLQLNPRERWKPMQAMQHPFI
Kinase CLK_b.AA HIPK 310-338 34 0.004099 5.1 In-house 301-329 (329) Show / Hide 
Range on Protein: 310-338
Range on HMM: 301-329/329
Sequence Identity: 34% (10 aa)

SLTDLLEGLLRYGASDRLTAKEALRHPFF
.  ..|  ..   |  |.|  |||.||| 
EFVHVLKKMCTWDAHKRITPCEALNHPFV