Gene DYRKP-2 (S.moellendorffii)

DYRKP-2

Species: S.moellendorffii
Alias: DYRKP-2
External Links:
Annotation:

Classification

Group: CMGC
Family: DYRK
Subfamily: DYRKP

Sequence

Name Sequence Type Origin Length Description Download
DYRKP-2.AA Protein None 288 None Fasta, JSON
DYRKP-2.NA RNA None 867 None Fasta, JSON
DYRKP-2.kin_dom Protein Kinase Domain None 275 None Fasta, JSON

Protein domain

Protein domains of DYRKP-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DYRKP-2.AA DyrkP 3-222 65 1.3e-124 412.64 In-house 27-246 (323) Show / Hide 
Range on Protein: 3-222
Range on HMM: 27-246/323
Sequence Identity: 65% (143 aa)

VCMKIIKNNKDFFDQSLDEIKLLKYINKHDPADKYHILRLYDYFYHREHLFIVCELLRANLYEFHKYNRDSGGEVYFTMPRLQSITRQCLEALEFLHGLG
.||||| ||||.||||.||||||.|||     |   .|| ||||||.|||||. |||. ||||| |.||.     |||. ||| || | | ||...| | 
MCMKIIENNKDYFDQSIDEIKLLRYINYNGDVDEKNVLRYYDYFYHKEHLFIITELLKDNLYEFYKFNRENEQQRYFTVGRLQKITQQILIALDYIHSLR

LIHCDLKPENILVKSYSRCEVKVIDLGSSCFQSDHLCSYVQSRSYRAPEVILGLPYDQKIDIWSLGCILAELCSGNVLFQNDSLATLLARVVGIIGPLDP
||||||||||||.|||..|.||.|| |||||  ||| ||||||||||||||.|  || .||.||||||||||  |||||||| .  |||||.|||||.  
LIHCDLKPENILMKSYPKCQVKIIDFGSSCFIHDHLSSYVQSRSYRAPEVIIGCKYDYRIDMWSLGCILAELWTGNVLFQNDNIQGLLARVIGIIGPFPE

EMVARGRESYKFLTKNSKLY
 |.  ||    | |..  ||
WMMQEGRLVQNFFTRKRLLY
Kinase DYRKP-2.AA DYRK 2-279 41 4.1e-118 398.69 In-house 26-320 (320) Show / Hide 
Range on Protein: 2-279
Range on HMM: 26-320/320
Sequence Identity: 41% (124 aa)

DVCMKIIKNNKDFFDQSLDEIKLLKYINKHDPADKYHILRLYDYFYHREHLFIVCELLRANLYEFHKYNRDSGGEVYFTMPRLQSITRQCLEALEFLHGL
.|..|||.|||.|..|...|||.|.|.|..|| ||||....|||||||.||.|| |||  ||||| | |.  |.   |.. . .....| |..| ||| .
MVAIKIIRNNKRFHRQAQIEIKILEYLNQQDPDDKYHCVHMYDYFYHRNHLCIVFELLSMNLYEFLKNNHFQGF---FSLNLVRKFAQQILTCLKFLHKN

-GLIHCDLKPENILVKSY-SRCEVKVIDLGSSCFQSDHLCSYVQSRSYRAPEVILGLPYDQKIDIWSLGCILAELCSGNVLFQNDSLATLLARVVGIIGP
  .||||||||||..|.  .....|||| ||||| .... .|.||| |||||||||.||. .||.||||||||||  |..||....   .||... ..|.
ENIIHCDLKPENIMLKQPRNKSTIKVIDFGSSCFEHQRIYTYIQSRFYRAPEVILGCPYCYAIDMWSLGCILAELFTGWPLFPGENEYDQLACIMEVLGM

LDPEMVARG--RESYKFLTK----------NSKL------YERNQETSRMEYLIPKKTTLAHRLPMGDQGFLEFVAFLLQINPKNRPSAAEALKHPWL
  ..|.  |  |   || ..          ...       . ....|.| ....|... . .|.   |. |. |.  .||..|..|.....||.|||.
PPKWMIDKGRCRRKHKFFDCFMYCECDEWTKQNKITDHYMTPKCHPTKRGQRRPPGRRNWDPRHQCDDHQFKDFIKKCLQWDPHKRITPSQALQHPWF
Kinase DYRKP-2.AA CMGC 3-279 19 1.5e-83 274.26 In-house 41-513 (513) Show / Hide 
Range on Protein: 3-279
Range on HMM: 41-513/513
Sequence Identity: 19% (92 aa)

VCMKIIKNNKDFFDQSL-------------DEIKLLKYIN-KHDPAD-----------KYHILRLYDYFYHRE-----------------HLFIVCELLR
| .|.|||.. . .| .             .|||.||..| .||| .           . .|..|||.|||..                 ||..| |.. 
VAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDP-NWQRRDDPDNKHHNNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMD

ANLYEFHKYNR--DSG-GEVYFTMPR------------LQSIT------RQCLEALE--FLHGLG--LIHCDLKPENILVKS------------------
 .||.. | |.  . | . ....                ....      .| |..|.  ..|  .   ||.||||||||. .                  
HDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPC

YSRCEVKVIDLGSSCFQSDH------------------------LCSYVQSRSYRAPEVILGLP----------YDQKIDIWSLGCILAELCSG------
... ..|..| |.... ..|                        . .||..| |||||..|| .          |...||.||.|||.||.  |      
QKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIF

--NVLFQNDSL-----------ATLLARVVGIIGPLDPEMVARGRES-------YKFLTKNSKLYERNQETS------------------------RMEY
    ||. .|               |.. . ..|. . .|  .|. .        .   . .||...|.  .                          ..
RGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPT-WMIQKGK-RHFNFCKHEEEWPNMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWW

LIPKKTTLAHRLP--------------------------------MGDQGFLEFVAFLLQINPKNRPSAAEALKHPWL
  .. . |  ..|                                . |. .....  .||..|..|..|..||.||..
PPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase DYRKP-2.AA DYRK2 3-181 46 1.6e-70 228.5 In-house 27-202 (318) Show / Hide 
Range on Protein: 3-181
Range on HMM: 27-202/318
Sequence Identity: 46% (84 aa)

VCMKIIKNNKDFFDQSLDEIKLLKYINKHDPADKYHILRLYDYFYHREHLFIVCELLRANLYEFHKYNRDSGGEVYFTMPRLQSITRQCLEALEFLHGLG
|. |.| | | |  | . ||. |..| ..|.   . . .. |||| | |..|. |||  ||||. | |   |    |..      ... |..|.|||   
VAIKMIRNKKRFHNQAYEEIRILHHIRRQDKDNTMNCVHMLDYFYFRNHHCITFELLSMNLYEYIKKNHFQG----FSLQLVRRFAHSILQCLRFLHKNN

LIHCDLKPENILVKSYSRCEVKVIDLGSSCFQSD-HLCSYVQSRSYRAPEVILGLPYDQKIDIWSLGCILAELCSGNVLF
.||||||||||| |.  |  .|||| |||||    ..  |.||| |||||||||..|.  ||.||.|||.||| .|  ||
IIHCDLKPENILLKQWNRSGIKVIDFGSSCFEHQYRIYTYIQSRFYRAPEVILGGKYGMAIDMWSFGCIMAELYTGYPLF
Kinase DYRKP-2.AA DYRK1 3-241 38 2.6e-57 196.72 In-house 27-265 (321) Show / Hide 
Range on Protein: 3-241
Range on HMM: 27-265/321
Sequence Identity: 38% (93 aa)

VCMKIIKNNKDFFDQSLDEIKLLKYINKHDPADKYHILRLYDYFYHREHLFIVCELLRANLYEFHKYNRDSGGEVYFTMPRLQSITRQCLEALEFLHG--
| .||||| | |..| . ||.||  .||||. .||.|..|   | .|.|| .| |||  |||.  .     |  .  |    . . .| . || |.    
VAIKIIKNKKPFYNQAQIEIRLLELMNKHDKEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLT----RKFAQQMCTALLFMSTPE

LGLIHCDLKPENILVKSYSRCEVKVIDLGSSCFQSDHLCSYVQSRSYRAPEVILGLPYDQKIDIWSLGCILAELCSGNVLFQNDSLATLLARVVGIIGPL
| .|||||||||||.    |  .|.|| ||||   . .  |.||| ||.|||.||..|| .||.||||||| |.  |  ||   .    . ..| ..|  
LDIIHCDLKPENILLCNPKRSAIKIIDFGSSCQLGQRIYQYIQSRFYRSPEVLLGIEYDMAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNKIVEVLGMP

DPEMVARGRESYKFLTK--NSKLYERNQETSRMEYLIPKKTTL
  .|. ..  . |. .|  .   | . ..  . .|  | .  |
PKHMIDQAPKAHKYFEKDPDNTWYCKKTRDKKKHYKEPCTRKL
Kinase DYRKP-2.AA YAK 6-174 43 6e-56 188.4 In-house 30-198 (347) Show / Hide 
Range on Protein: 6-174
Range on HMM: 30-198/347
Sequence Identity: 43% (76 aa)

KIIKNNKDFFDQSLDEIKLLKYIN-KHDPADKY---HILRLYDYFYHREHLFIVCELLRANLYEFHKYNRDSGGEVYFTMPRLQSITRQCLEALEFLHGL
|.|||   .| |.  ||..|.  | .||| .|    ||||.||.| |. |. .| |.|  ||||. | |.  |    | .   .  | | |...  |   
KVIKNRQAYFQQAKNEIQILRVLNQQHDPNNKNYQKHILRMYDFFVHKNHFCLVFEMLSNNLYEYLKQNKFCG----FSFQLIRQWTKQILDGMCVLENK

GLIHCDLKPENILVKSYSRCEVKVIDLGSSCFQSDHLCSYVQSRSYRAPEVILGLPYDQKIDIWSLGCILAEL
 .||||||||||. .   . |.|.|| ||||     .  |.|.| ||.||.|.. .|   || ||||||.|||
QIIHCDLKPENIMLCKPNKPEIKIIDFGSSCQEKKMVYTYIQQRHYRSPEIIVWMIYCTSIDMWSLGCIVAEL
Kinase DYRKP-2.AA Pkinase 3-279 25 5.6e-53 187.11 Pfam 27-293 (293) Show / Hide 
Range on Protein: 3-279
Range on HMM: 27-293/293
Sequence Identity: 25% (76 aa)

VCMKIIKNNKDFFDQ---SLD--EIKLLKYINKHDPADKYHILRLYDYFYHREHLFIVCELLRANLYEFHKYN----RDSGGEVYFTMPRLQSITRQCLE
|..||||  ..  ..    .   ||...| . .|.     .|.||||.|. . |. .| |...  ||          ....| .||..  .... .| |.
VAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHP-----NIVRLYDWFEDKDHIYMVMEYCEGGLY-VMDLFDYISTWRHGCFYFSEWECKFYMYQILR

ALEFLHGLGLIHCDLKPENILVKSYSRCEV----KVIDLGSSC---FQSDHLCSYVQSRSYRAPEVIL-GLPYDQKIDIWSLGCILAELCSGNVLFQND-
.||..|  | ||.||||||||..  .....    |..| |...     .... ... .. |.|||||. | .|..|.|.||.||||.|...|. .|... 
GLEYCHSMGIIHRDLKPENILID--NNGHIDACVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHC

---SLATLLARVVGIIGPLDPEMVARGRESYKFLTKNSKLYERNQETSRMEYLIPKKTTLAHRLPMGDQGFLEFVAFLLQINPKNRPSAAEALKHPWL
   . .. ..... | ||  ..     .. . |   .    .               . .  . .  .. ...|.  .|. .|| ||.|...|.|||.
WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H---------------F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
S_TKc DYRKP-2.AA S_TKc 1-279 23 2.5e-52 181.06 SMART 19-231 (231) Show / Hide 
Range on Protein: 1-279
Range on HMM: 19-231/231
Sequence Identity: 23% (71 aa)

MD------VCMKIIKNNKDFFDQSLDEIKLLKYINKHDPADKYHILRLYDYFYHREHLFIVCELLRA---NLYEFHKYNRDSGGEVYFTMPRLQSITRQC
 .      | .||||      .. . ||..||        .  .| .|||.|.. .||..| |..     .|... | ..  |. ..|.  . .....| 
RHKKTGRIVAIKIIK------EHIRREIQILKK-------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQI

LEALEFLHGLGLIHCDLKPENILVKSYSRCEVKVIDLGSSCFQSDHLCSYVQSRSYRAPEVILGLPYDQ-KIDIWSLGCILAELCSGNVLFQNDSLATLL
..|||..| .| ||.||||||||. .    ..|..| |....      ... .. |.||||.   .|.  |.|.||.||||.|...|  .|.   .....
CCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMF

ARVVGIIGPLDPEMVARGRESYKFLTKNSKLYERNQETSRMEYLIPKKTTLAHRLPMGDQGFLEFVAFLLQINPKNRPSAAEALK-------HPWL
 ...                                                      .. ...|.  .|| .|..||.| |||.       |||.
KKIG------------------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase DYRKP-2.AA HIPK 3-185 43 4.5e-50 155.62 In-house 27-207 (329) Show / Hide 
Range on Protein: 3-185
Range on HMM: 27-207/329
Sequence Identity: 43% (80 aa)

VCMKIIKNNKDFFDQSLDEIKLLKYINKHDPADKYHILRLYDYFYHREHLFIVCELLRANLYEFHKYNRDSGGEVYFTMPRLQSITRQCLEALEFLHGLG
| .||.||.  .  |   |...|. . . . || ||..| |..| |..| ..| |.|  |||.| | |. .       .  .  |. | | ||  |  ||
VAIKILKNHPYYARQGQIEVSILHCLSQEN-ADEYHFVRAYECFHHKNHTCLVFEMLEQNLYDFQKQNKFMP----LPLKHIRPILQQVLTALMKLKELG

LIHCDLKPENILVKSYSRC--EVKVIDLGSSCFQSDHLCS-YVQSRSYRAPEVILGLPYDQKIDIWSLGCILAELCSGNVLFQNDS
||| |||||||.    .||   ||||| ||    |.  |. |.||| |||||.|||||. ...|.|||||..|||  |  |. . .
LIHADLKPENIMLVDPTRCPYRVKVIDFGSASHVSKVVCNTYLQSRYYRAPEIILGLPFCENHDMWSLGCVIAELFLGWPLYPGAD
Kinase DYRKP-2.AA PRP4 2-181 38 1.5e-35 124.45 In-house 27-205 (320) Show / Hide 
Range on Protein: 2-181
Range on HMM: 27-205/320
Sequence Identity: 38% (71 aa)

DVCMKIIKNNKDFFDQSLDEIKLLKYINKH--DPADKYHILRLYDYFYHREHLFIVCELLRANLYE-FHKYNRDSGGEVYFTMPRLQSITRQCLEALEFL
.|  ||| ||    .  | |.  |. .|    |. ||.|..|... |.|| |. .| | .  || |   || .| |    . .    | ..| . ||  |
MVAIKIIRNNEIMHKTGLRELEILQKLNDAPTDKNDKFHCVRMFRHFNHRQHMCLVFECMSMNLREVLKKYGKDVG----LHLKAVRSYAQQLFLALKHL

HGLGLIHCDLKPENILVKSYSRCEVKVIDLGS-SCFQSDHLCSYVQSRSYRAPEVILGLPYDQKIDIWSLGCILAELCSGNVLF
  .. .| |.|| |||| . |.   | .| || |  .   .  | .|| |||||.|.| |||  ||.|| || |.||  | ..|
KKCNILHADIKPDNILV-NESKNTLKMCDFGSASHIHENEITPYLVSRFYRAPEIIIGHPYDYQIDMWSVGCTLYELYTGKIMF
Kinase DYRKP-2.AA Ciliate-E2 38-181 25 5.4e-30 100.13 In-house 93-296 (365) Show / Hide 
Range on Protein: 38-181
Range on HMM: 93-296/365
Sequence Identity: 25% (53 aa)

HILRLYDYFY--HREHLFIVCELLRA-NLYEFHKYNRDSGGEV-----YFTMPRLQSITRQCLE---------------ALEFLHGLG-LIHCDLKPENI
.|...|..|.   ......| |..   .|... | |. . ..      |||.   . |..| |.               |||.||  .  || |.|||||
NIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENI

LVKSYSRCEVKVIDLGSSCFQSDH-----------LCSYVQ------------------------SRSYRAPEVILGLP---------YDQKIDIWSLGC
|.       .|.||.| | ...|            .. . .                        .  | |||.. | .         || |.||||||.
LF-------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGV

ILAELCSGNVLF
|| |...|.  |
ILYEMLFGKPPF
Kinase DYRKP-2.AA CLK 3-114 33 1.5e-27 79.04 In-house 28-146 (350) Show / Hide 
Range on Protein: 3-114
Range on HMM: 28-146/350
Sequence Identity: 33% (40 aa)

VCMKIIKNNKDFFDQSLDEIK-LLKYINKH-DPADKYH--ILRLYDYFYH-REHLFIVCELLRANLYEFHKYNR---DSGGEVYFTMPRLQSITRQCLEA
|  |||.| . . ...  ||.  .| ||.  ||  ||   .....|.| .   |  || ||.  ..|.| | |.       .  . .   .....| .||
VALKIIRNVEKYREAAWVEINQIMKKINEKHDPNNKYWEHCWKMNDWFDYGHGHICIVFELYGLSIYDFMKSNNSKMPN-KYIPYPIDHIRHMAYQLCEA

LEFLHGLGLIHCDLKPENIL
..||| ..|.| |||||||.
VKFLHDMKLTHTDLKPENIC
Kinase DYRKP-2.AA CLK 121-182 50 2.9e-25 72.1 In-house 184-248 (350) Show / Hide 
Range on Protein: 121-182
Range on HMM: 184-248/350
Sequence Identity: 50% (33 aa)

CEVKVIDLGSSC---FQSDHLCSYVQSRSYRAPEVILGLPYDQKIDIWSLGCILAELCSGNVLFQ
....||| ||     |   |    |..| ||||||||||.. |. |.|| |||| || .|  |||
THICVIDFGSATKIRFDHEHHSTIVSTRHYRAPEVILGLGWSQPCDVWSIGCILFELYTGFTLFQ
Kinase DYRKP-2.AA DyrkP 224-279 42 2e-16 49.97 In-house 268-323 (323) Show / Hide 
Range on Protein: 224-279
Range on HMM: 268-323/323
Sequence Identity: 42% (24 aa)

RNQETSRMEYLIPKKTTLAHRLPMGDQGFLEFVAFLLQINPKNRPSAAEALKHPWL
. | | ..  |.||.  |  ||   |  |..||  .|||    ||.| |||.|||.
QRQKTGKIQILVPKHSNLRARLRTDDHMFIDFVRQCLQIDFTRRPTAKEALQHPWF
Kinase DYRKP-2.AA Ciliate-E2 259-279 36 5.7e-09 26.92 In-house 344-365 (365) Show / Hide 
Range on Protein: 259-279
Range on HMM: 344-365/365
Sequence Identity: 36% (8 aa)

LLQINPKNRPS-AAEALKHPWL
.|| .|..|.. . ..|.|||.
MLQKDPEKRITGWEQILNHPWF
Kinase DYRKP-2.AA DYRK2 235-279 28 2.8e-08 22.68 In-house 273-318 (318) Show / Hide 
Range on Protein: 235-279
Range on HMM: 273-318/318
Sequence Identity: 28% (13 aa)

IPKKTTLAHRLP-MGDQGFLEFVAFLLQINPKNRPSAAEALKHPWL
.|  . ... |. ..|. |..|.   ..  |. | ....||||||.
PPGSKSWKSVLKGCEDENFIDFIKRCFEWDPSERMTPSQALKHPWI
Kinase DYRKP-2.AA TyrKc 3-279 17 1.9e-07 -102.08 SMART 1-280 (280) Show / Hide 
Range on Protein: 3-279
Range on HMM: 1-280/280
Sequence Identity: 17% (58 aa)

VCM-----------------------KIIKNNKDFFDQSLDEIKLLKYI-NKHDPADKYHILRLYDYFYHR-------EHLFIVCELLRANLYEFHKYNR
. .                       | .|...      ..|..... .  .|.     .|.||| .  .        | |.|| |.  . .   ..| |
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA--REDFMREARIMCKLGGHHP-----NIVRLYGVCTQQGRNFMYIEPLMIVMEY--MPHGDLKDYLR

DSGGEVYFTMPRLQSITRQCLEALEFLHGLGLIHCDLKPENILVKSYSRCEVKVIDLGSSCFQSDH-LC----SYVQSR---SYR--------APEVILG
.....  ..|. | |.  |  .  |.||  ..|| ||   |.||.  ..  ||. | | | .  |.  .    .|  ..   . .        |||.|  
KHRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVG--ENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINY

LPYDQKIDIWSLGCILAELCS-GNVLFQN-----DSLATLLARVVGIIGPLDPEM----VARGRESYKFLTKNSKLYERNQETSRMEYLIPKKTTLAHRL
  .  | |.|| |  . |... |     .      | . ....|     .  |.                                              
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS----------------------------------------

PMGDQGFLEFVAFLLQI-------NPKNRPSAAEALKHPWL
      | .  . . ||       .|..||. .|   |  .
------FVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase DYRKP-2.AA YAK 252-279 39 7e-06 15.44 In-house 320-347 (347) Show / Hide 
Range on Protein: 252-279
Range on HMM: 320-347/347
Sequence Identity: 39% (11 aa)

FLEFVAFLLQINPKNRPSAAEALKHPWL
|. |.  ||| ||. | ..  | .|| .
FIDFINQLLQLNPRERWKPMQAMQHPFI
Kinase DYRKP-2.AA CLK 259-279 33 1.2e-05 12.07 In-house 330-350 (350) Show / Hide 
Range on Protein: 259-279
Range on HMM: 330-350/350
Sequence Identity: 33% (7 aa)

LLQINPKNRPSAAEALKHPWL
.| . |  |.....||.||. 
MLEYDPSKRITCKDALQHPFF
Kinase DYRKP-2.AA PRP4 259-279 47 0.000332 11.39 In-house 300-320 (320) Show / Hide 
Range on Protein: 259-279
Range on HMM: 300-320/320
Sequence Identity: 47% (10 aa)

LLQINPKNRPSAAEALKHPWL
.|.  ||.| .  |||||| .
CLMLDPKKRITCNEALKHPFI
Kinase DYRKP-2.AA DYRK1 252-279 32 0.01019 4.8 In-house 294-321 (321) Show / Hide 
Range on Protein: 252-279
Range on HMM: 294-321/321
Sequence Identity: 32% (9 aa)

FLEFVAFLLQINPKNRPSAAEALKHPWL
| . .  .|| .||.| .  .||.|...
FKDLIKRMLQYDPKQRITPYYALQHSFF
Kinase DYRKP-2.AA HIPK 259-279 28 0.070983 1.13 In-house 309-329 (329) Show / Hide 
Range on Protein: 259-279
Range on HMM: 309-329/329
Sequence Identity: 28% (6 aa)

LLQINPKNRPSAAEALKHPWL
.. .....| . .|||.||. 
MCTWDAHKRITPCEALNHPFV