Gene ERK7 (S.moellendorffii)

ERK7

Species: S.moellendorffii
Alias: ERK7
External Links:
Annotation:

Classification

Group: CMGC
Family: MAPK
Subfamily: ERK1

Sequence

Name Sequence Type Origin Length Description Download
ERK7.AA Protein None 380 None Fasta, JSON
ERK7.NA RNA None 1143 None Fasta, JSON
ERK7.kin_dom Protein Kinase Domain None 292 None Fasta, JSON

Protein domain

Protein domains of ERK7.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase ERK7.AA ERK7 13-304 65 2.4e-198 665.22 In-house 1-292 (292) Show / Hide 
Range on Protein: 13-304
Range on HMM: 1-292/292
Sequence Identity: 65% (191 aa)

YHVCQKLGKGAYGIVWKAFDRKTNDVVALKKIFDAFQNSTDAQRTFREVMFLQEINDHENVIKLTNVLKAENDRDLYLVFEYMETDLHAVIR-ANILEDV
| . ..||||||||||||.|..| .|||||||||||.|.|||||||||.|||||...|.|.|.| ||..|.||||.|||||.|||||||||| .|||.|.
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIRADNDRDIYLVFEFMETDLHAVIRKGNILKDI

HKQYIMYQLFKSLKYLHSAGLLHRDIKPSNLLLDSDCRCKLADFGLARSVAQLKDDMGQAQVLTDYVATRWYRAPEILLGSTNYTFGVDMWSSGCILGEL
|||||||||.. .||.||. ..|||.||||.||||.|. |..|||||||.||...   | ..||.||||||||||||||||..|| |||||| ||||||.
HKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCILGEM

LNGKPVFPGASTMNQIEKVLDLIGKPASEDIAAFESPFAAAMIENMAITGPSRSFRKAFPSATPEAADLLRKLLHFNPQKRLTAEQALQHPYV
| |||.||| ||||||||.|..|.||  |||.| .| .|. |.|.|  . . ... . .|.. ..| |||..|| |||.||||||||||||||
LRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMN-QQKRKTLDQMMPQCCDDAIDLLKRLLVFNPKKRLTAEQALQHPYV
Kinase ERK7.AA MAPK 13-304 41 2.3e-163 548.99 In-house 1-328 (328) Show / Hide 
Range on Protein: 13-304
Range on HMM: 1-328/328
Sequence Identity: 41% (137 aa)

YHVCQKLGKGAYGIVWKAFDRK------TNDVVALKKIFDAFQNSTDAQRTFREVMFLQEINDHENVIKLTNVLKAE-----ND----RDLYLVFEYMET
|   ...|.||||.|..|.|..      ... ||.|||...||| |...||.||...|.....|||.||| .....|     |.    .|.|.|.|.|||
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

DLHAVIR-ANILEDVHKQYIMYQLFKS--LKYLHSAGLLHRDIKPSNLLLDSDCRCKLADFGLARSVAQLKDDMGQ--------AQVLTDYVATRWYRAP
|||..|.  ..|.| |.||.|||. .   |||.|||. .|||.||||.|....|  |..|||||||... . . .|        .  .|.||||||||||
DLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAP

EILLG--STNYTFGVDMWSSGCILGELLN-GKPVFPGASTMNQIEKVLDLIGKPASEDIAAFE-SPFAAAMIENM--AITGPSRSFRKAFPS----ATPE
||.|.  ...|| .||||| |||..|.|. .|| ||| ....|........|.|  |.|   . |. |. .|...      | ....| ||     |.|.
EIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQ

AADLLRKLLHFNPQKRLTAEQALQHPYV
| ||| |.|.|.|.||.|.|.||||||.
AIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase ERK7.AA CMGC 13-304 25 3.7e-136 450.37 In-house 1-513 (513) Show / Hide 
Range on Protein: 13-304
Range on HMM: 1-513/513
Sequence Identity: 25% (133 aa)

YHVCQKLGKGAYGIVWKAFD--------------RKTNDVVALKKIFDAFQNSTDAQ----------RTFREVMFLQEIN----------------DHEN
|.. .|.|.|.||.|.|..|              ..|| .||.|||. .| . ..|.          |..||...|...|                .|.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

VIKLTNVLKAEN---------------DRDLYLVFEYMETDLHAVIRAN----------ILEDVH------------KQYIM------YQLFKSLK--YL
..|| .... .|               ...||||||||..||. .|. |           |.. |            ..|.|      ||....||  |.
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSAG--LLHRDIKPSNLLLDSDCRC--------------------KLADFGLARSVAQLKDDMGQAQV---------------LTDYVATRWYRAPEILL
||..   .|||.||.|.|....|..                    |..||||||.. . .|. .| |                .|.||.|||||||||||
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

GS---------TNYTFGVDMWSSGCILGELLNG--------KPVFP-----------GASTMNQIEKVLDLIGKP----------------ASEDIAAFE
|.         ..|| ..|||| |||..|...|        || ||           |.|. .|..|  ...|.|                  |..   .
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

--------------------SPFAAAMIEN--MAITGPSRSFRKAFPS-----------------------------------ATPEAADLLRKLLHFNP
                    |.||   |..     . | ..... ||                                    ..|.| ||| |.|...|
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

QKRLTAEQALQHPYV
.||.|||||||||| 
DKRITAEQALQHPYF
Kinase ERK7.AA ERK 13-304 42 2.5e-128 432.63 In-house 1-307 (307) Show / Hide 
Range on Protein: 13-304
Range on HMM: 1-307/307
Sequence Identity: 42% (131 aa)

YHVCQKLGKGAYGIVWKAFDRK-----TNDVVALKKIFDAFQNSTDAQRTFREVMFLQEINDHENVIKLTNVLKAE---NDRDLYLVFEYMETDLHAVIR
|.  ...|.||||.| .|.| .     |.. || |||..|| .  .. || ||  .|   . |||.|.| .... .   .  |.|.|.|.|||||| .|.
YQIIKQIGHGAYGVVCSAIDKEYCFDETGQKVAIKKIENAFDHPIYCKRTLREIKLLRHFKGHENIICLFDIMMPNSPEQYNDIYCVEELMETDLHQIIN

AN-ILEDVHKQYIMYQLFKSLKYLHSAGLLHRDIKPSNLLLDSDCRCKLADFGLAR----SVAQLKDDMGQAQVLTDYVATRWYRAPEILLGSTNYTFGV
    |.| | || |||.   |||.|||. .|||.||||.|. |.|  | .||||||    |..      .... .|.||||||||||||.|  ..||  .
SQQELSDDHCQYFMYQILCGLKYIHSANVIHRDLKPSNILVNSNCDLKICDFGLARCFDASYQENHE--CNQNFMTEYVATRWYRAPEIMLSWQKYTKAM

DMWSSGCILGELLNGKPVFPGASTMNQIEKVLDLIGKP-ASEDIAAFESPFAAAMIENMAI-TGPSRSFRKAFPSAT--PEAADLLRKLLHFNPQKRLTA
|.|| |||. |.|..||.|||.....||. ....||.|   ||.  ..|. |  .| |.     | ... . ||.|   |.| |||.|.|.|.|.||.|.
DIWSCGCIFAEMLGRKPLFPGKDYVHQINRIFQIIGTPHSEEDLQYICSENAWKYIKNLPNPVRPPKPWENIFPNANCNPQAIDLLEKMLVFDPDKRITV

EQALQHPYV
|..|.||| 
EECLEHPYF
Kinase ERK7.AA p38 13-304 41 1.7e-104 353.43 In-house 1-289 (289) Show / Hide 
Range on Protein: 13-304
Range on HMM: 1-289/289
Sequence Identity: 41% (125 aa)

YHVCQKLGKGAYGIVWKAFDRKTNDV---VALKKIFDAFQNSTDAQRTFREVMFLQEINDHENVIKLTNVLKA-----ENDRDLYLVFEYMETDLHAVIR
|   | .|.|||| | ||.||.|..    || ||..  ||   .| ||.||.  |. .. |||||.| .|        .. .| |.| . |..||. ...
YQNLQPVGSGAYGQVCKAEDRRTGQKRRYVAIKKLMRPFQSEIHAKRTYRELRLLKHMR-HENVICLLDVFTPPAHSMNDFQDVYMVTHFMGADLNNIMK

ANILEDVHKQYIMYQLFKSLKYLHSAGLLHRDIKPSNLLLDSDCRCKLADFGLARSVAQLKDDMGQAQVLTDYVATRWYRAPEILLGSTNYTFGVDMWSS
   | | | |.. ||. . ||| ||||  ||| ||||. .  ||  .  ||||||          ... .|.||||||||||||.|    ||  ||.|| 
CQRLSDDHIQFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDCELRILDFGLAR---------HCDDEMTGYVATRWYRAPEIMLNWMHYTQTVDIWSV

GCILGELLNGKPVFPGASTMNQIEKVLDLIGKPASEDIAAFESPFAAAMIENMAITGPSRSFRKAFPSATPEAADLLRKLLHFNPQKRLTAEQALQHPYV
|||. ||. |.. |||   ..|..... ..|.|. | ..  .|  | . |.... . | | |.. |. |.| |.||| |.|.  | ||.|||.|.|||| 
GCIMAELITGRTLFPGDDHIDQLQRIMKVCGTPDEEFWQKIQSEEARNYIQSYPQM-PRRDFHHVFMGANPQAIDLLEKMLELDPDKRITAEEAMQHPYF
Kinase ERK7.AA CDK 13-304 33 1.2e-99 319.44 In-house 1-284 (284) Show / Hide 
Range on Protein: 13-304
Range on HMM: 1-284/284
Sequence Identity: 33% (108 aa)

YHVCQKLGKGAYGIVWKAFDRKTN-----DVVALKKIF----------DAFQNSTDAQRTFREVMFLQEINDHENVIKLTNVLKAEN---------DRDL
|  ..|.| |.||.| || |..|.     ..||||||           . |  .     . ||.  |.|.  |.|..||  |   .|         .. |
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPIT-----AIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKL

YLVFEYMETDLHAVIRANILEDVHKQYIMYQLFKSLKYLHSAGLLHRDIKPSNLLLDSDCR-----CKLADFGLARSVAQLKD-DMGQAQVLTDYVATRW
|.|||||..||  ...         . .|.|| . | |.|| . .|||.||.|.|....        |.|||||||     .. . .  ...|  | |.|
YMVFEYMDHDLKKYMD--------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMS-EPNRTYTHEVVTLW

YRAPEILLGSTNYT--FGVDMWSSGCILGELLN---GKPVFPGASTMNQIEKVLDLIGKPASEDIAAFESPFAAAMIENMAITGPSRSFRKAFPSATPEA
|||||.||||..|.   ..|||| |||..|...   .|| ||| |  .|..|. ...| |  ..   ...                              
YRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY--------------------------

ADLLRKLLHFNPQKRLTAEQALQHPYV
 ||| |.| ..|.||..||||||||| 
-DLLNKMLCYDPKKRISAEQALQHPYF
Kinase ERK7.AA S_TKc 13-304 31 2.5e-99 337.22 SMART 1-231 (231) Show / Hide 
Range on Protein: 13-304
Range on HMM: 1-231/231
Sequence Identity: 31% (98 aa)

YHVCQKLGKGAYGIVWKAFDRKTNDVVALKKIFDAFQNSTDAQRTFREVMFLQEINDHENVIKLTNVLKAENDRDLYLVFEYMET---DLHAVIRANI--
|.. .|.||||.| |.|. ..||. .||.|.|          ... ||.  |..  .|.|..||  |       .||.|.||...   ||. .|. .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----LEDVHKQYIMYQLFKSLKYLHSAGLLHRDIKPSNLLLDSDCRCKLADFGLARSVAQLKDDMGQAQVLTDYVATRWYRAPEILLGSTNYTF-GVDM
     .   | ...|||... |.|.|| | .|||.||.|.|||.  . |..|||||| .             | .. |.||.|||.|     |..  .|.
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------------TTFCGTPWYMAPEVL----GYGKCKCDW

WSSGCILGELLNGKPVFPGASTMNQIEKVLDLIGKPASEDIAAFESPFAAAMIENMAITGPSRSFRKAFPSATPEAADLLRKLLHFNPQKRLTAEQALQ-
|| |||| |.| |.| ||      |.......||                                      .||| |..||.|...|.||.|| .||| 
WSCGCILYEMLCGYPPFP------QMQMMFKKIG--------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQD

------HPYV
      ||..
EWDIKCHPWF
Kinase ERK7.AA Pkinase 13-304 30 6.5e-96 329.74 Pfam 1-293 (293) Show / Hide 
Range on Protein: 13-304
Range on HMM: 1-293/293
Sequence Identity: 30% (95 aa)

YHVCQKLGKGAYGIVWKAFDRKTNDVVALKKIFDAFQNSTDAQRTFR--EVMFLQEINDHENVIKLTNVLKAENDRDLYLVFEYMET-----DLHAVIR-
||. .|.|.|..| |.|. ...|...||.|.|    ..|   |. .|  |.  .... .|.|...|  .     ....|.|.||.|      ||...|. 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST

--ANIL--EDVHKQYIMYQLFKSLKYLHSAGLLHRDIKPSNLLLDSDCRC----KLADFGLARSVAQLKDDMGQAQVLTDYVATRWYRAPEILLGSTNYT
   . .  .. . . .|||... |.|.|| | .|||.||.|.|.|... .    |..|||||. .          . .|... |.||.|||...|.. |.
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-----Y-NNS-MTTFCGTPWYMAPEVIRGGQYYG

FGVDMWSSGCILGELLNGKPVFPGA----STMNQIEKVLDLIGKPASEDIAAF--ESPFAAAMIENMAITGPSRSFRKAFPSATPEAADLLRKLLHFNPQ
  ||||| |||| |.|.|.| |||.    . ..|....    |.| ..|.     .|.|   ..   .     . ...  . ...|. |.....|...|.
PKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-----F-HWTF-HNWSEECKDFIKWCLCKDPK

KRLTAEQALQHPYV
||.||||.||||..
KRPTAEQILQHPWF
Kinase ERK7.AA ERK1 13-304 43 1.1e-90 307.54 In-house 1-289 (289) Show / Hide 
Range on Protein: 13-304
Range on HMM: 1-289/289
Sequence Identity: 43% (129 aa)

YHVCQKLGKGAYGIVWKAFDRKTNDVVALKKIFDAFQNSTDAQRTFREVMFLQEINDHENVIKLTNVLKA---ENDRDLYLVFEYMETDLHAVIRANILE
|   | .|.||||.|  | |. ... ||.|||   |   |  ||| ||.  |.  . |||.|.. ....|   |. ||.|.| . |||||  ....  | 
YTNLQYIGEGAYGMVCSAYDTVHKQRVAIKKI-SPFEHQTYCQRTLREIKILTRFK-HENIINIQDIIRADTIEQMRDVYIVQCLMETDLYKLLKTQHLS

DVHKQYIMYQLFKSLKYLHSAGLLHRDIKPSNLLLDSDCRCKLADFGLARSVAQLKDDMGQAQVLTDYVATRWYRAPEILLGSTNYTFGVDMWSSGCILG
  |  | .||. . |||.|||  ||||.|||||||   |  |. ||||||     .|  |    ||.||||||||||||.| |  ||  .|.|| |||| 
NDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARIADPEHDHTG---FLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILA

ELLNGKPVFPGASTMNQIEKVLDLIGKPASEDIAAFESPFAAAMIENMAITGPSRSFRKAFPSATPEAADLLRKLLHFNPQKRLTAEQALQHPYV
|.|  .|.|||   . |. ..| ..| |. .|.       | . .. .    |  .... || | . | ||| |.| |||.||.| |.|| |||.
EMLSNRPIFPGKHYLDQLNHILGVLGSPSQDDLNCIINEKARNYLQSLPHK-PKVPWARLFPKADSKALDLLDKMLTFNPHKRITVEEALAHPYL
Kinase ERK7.AA ERK5 13-304 39 1.4e-89 303.93 In-house 1-295 (295) Show / Hide 
Range on Protein: 13-304
Range on HMM: 1-295/295
Sequence Identity: 39% (118 aa)

YHVCQKLGKGAYGIVWKAFDRKTNDVVALKKIFDAFQNSTDAQRTFREVMFLQEINDHENVIKLTNVLKAEND----RDLYLVFEYMETDLHAVIRANI-
|..  |.| ||||.|  |  ||. . ||.|||  ||   | |.|||||.  |.    |.|.| . ..|. .      .| | ||. || ||| .| .|  
YKIIEKIGNGAYGVVCSARRRKNGQQVAIKKIPNAFDVVTNAKRTFRELKILRHFR-HDNIIAIRDILMPKVPYSEMKDVYVVFDLMESDLHQIIHSNQP

LEDVHKQYIMYQLFKSLKYLHSAGLLHRDIKPSNLLLDSDCRCKLADFGLARSVAQLKDDMGQAQVLTDYVATRWYRAPEILLGSTNYTFGVDMWSSGCI
.   |  | .||. . |||.|||  .|||.||||||    |  |. |||.|| .. .  |  |   .|.|||||||||||... | .||  .|.|| |||
FTLEHIRYFLYQILRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTFSPDKHQM-FMTEYVATRWYRAPELMFSSHDYTQAIDVWSVGCI

LGELLNGKPVFPGASTMNQIEKVLDLIGKPASEDIAAFESPFAAAMIEN-MAITGPSRSFRKAFPSATPEAADLLRKLLHFNPQKRLTAEQALQHPYV
.||..  . .|||   ..|.. ... .| |..  | |  .    . .   ..   | . . | .| | . | ||| ..| | | .|.|. .|||||..
FGEMIARRQMFPGKNYIHQLQLIMMVLGMPPPHMIQAVSADHVYNYFQKNFPNRQP-KDWEKVYPKADRQALDLLARMLRFEPSERITVNKALQHPFL
Kinase ERK7.AA CDC2 13-227 37 2.8e-76 233.83 In-house 1-218 (301) Show / Hide 
Range on Protein: 13-227
Range on HMM: 1-218/301
Sequence Identity: 37% (86 aa)

YHVCQKLGKGAYGIVWKAFDRKTNDVVALKKIFDAFQNSTDA----QRTFREVMFLQEINDHENVIKLTNVLKAENDRDLYLVFEYMETDLHAVIR----
|   .|.|.| ||.| |. |..||..||||||     . ..     . . ||   |.|..||.|..||  |..    . ||.||||.. ||    .    
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKI--RLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYLDMDLKKYMDMSIP

--ANILEDVHKQYIMYQLFKSLKYLHSAGLLHRDIKPSNLLLDSDCRCKLADFGLARSVAQLKDDMGQAQVLTD-YVATRWYRAPEILLGSTNYTFGVDM
   .. ... |.| |||. . . ..|. . .|||.||.|.|.|.. . |.||||||| .      .   . .|.  | |.||||||||||.  |...|||
KNKHMPPQLVKSY-MYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFG-----IPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDM

WSSGCILGEL---LNGKPVFPGASTMNQI
|| |||. |.    . || |.| |   |.
WSIGCIFAEMFMDVTKKPLFHGDSEIDQL
Kinase ERK7.AA MAPK-Unclassified 13-161 40 7.5e-62 211.8 In-house 1-159 (575) Show / Hide 
Range on Protein: 13-161
Range on HMM: 1-159/575
Sequence Identity: 40% (65 aa)

YHVCQKLGKGAYGIVWKAFDRKT-NDVVALKKIFDAFQNSTDAQRTFREVMFLQEINDHENVIKLTNVLKAENDRD-----LYLVFEYMET---DLHAVI
| . . .| ||||.| .| | |. |  || ||.  .|.| ||. |. ||.  | ..| |.|.|...... .. .       .|.| .||.|   ||| .|
YEYQKNIGSGAYGQVCRAMDKKNQNQQVAIKKVNHIFHNHTDCKRVLREIRILRYLN-HPNIIQIQDIFYNKELHNQEFDDIYIVMDYMQTSLFDLHQII

RANI--LEDVHKQYIMYQLFKSLKYLHSAGLLHRDIKPSNLLLDSDCRCKLADFGLARSV
. |.  ... | ||..||. . |||||||. .||| ||||||.. ||  . .|||..||.
KSNQDHWCHQHIQYFFYQILRGLKYLHSACIIHRDLKPSNLLINQDCSVRICDFGMSRSI
Kinase ERK7.AA MAPK-Unclassified 174-304 31 1.6e-43 150.91 In-house 405-575 (575) Show / Hide 
Range on Protein: 174-304
Range on HMM: 405-575/575
Sequence Identity: 31% (54 aa)

LTDYVATRWYRAPEILLGSTNYTFGVDMWSSGCILGELLNG-----------KPVFPGAS--------------------TMNQIEKVLDLIGKPASEDI
.| ||.|||||||||.| . .|.. ||.|| |||..|...            .| ||| .                       ||   .|  | |  ||.
MTQYVVTRWYRAPEIMLSMHEYDTQVDIWSIGCIFAEMMQMYDRHNPTFSDHRPLFPGQDCFPITPDRNNDVDQGGFPHSHQDQIKMIFDYLGMPPEEDC

AAFESPFAAAMIENMAITGPSRSFRKAFPSATP----------EAADLLRKLLHFNPQKRLTAEQALQHPYV
   ... |   |.  .   ..  |  ......|          |. |.. |.| |||.|| ||.|||.|||.
NFITCDSARKYIQSFK-CKTPVHFTDLMFCKAPGDDQIVRGNCECIDFVQKMLQFNPWKRITADQALEHPYF
Kinase ERK7.AA CDC2 266-304 39 8.2e-16 44.57 In-house 254-301 (301) Show / Hide 
Range on Protein: 266-304
Range on HMM: 254-301/301
Sequence Identity: 39% (19 aa)

FRKAFPS---------ATPEAADLLRKLLHFNPQKRLTAEQALQHPYV
..| .|.         ..||. |||...|. .||||..|..|||||| 
LSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQHPYF
Kinase ERK7.AA TyrKc 13-307 20 3.9e-15 22.02 SMART 1-280 (280) Show / Hide 
Range on Protein: 13-307
Range on HMM: 1-280/280
Sequence Identity: 20% (67 aa)

YHVCQKLGKGAYGIVWKAFDRKTNDVVALKKIF-DAFQNSTDAQRTFREVMFLQEI-NDHENVIKLTNVLKAE-----NDRDLYLVFEYMET-DLHAVIR
 .  .||| ||.|.|.|.  .     || |..  ||       .   ||   . ..  .|.|...|  |   .      .  |..|.|||.  ||.  .|
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

ANI--LEDVHKQYIMYQLFKSLKYLHSAGLLHRDIKPSNLLLDSDCRCKLADFGLARSVAQL------KDDMGQAQ-VLTDY-VATRWYRAPEILLGSTN
..   |   .. ....|  .   |||| .. |||.   | |.... ..| .||||.| .         ||   ...   ... .  ||. ||| .   ..
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECI--NYG

-YTFGVDMWSSGCILGELL-NGKPVFPGA----STMNQIEKVLDLIGKPASEDI----AAFESPFAAAMIENMAITGPSRSFRKAFPSATPEAADLLRKL
 .|.  | || |  . |.. .|..  ||      .  .. . ..  . .   .     .                          |. ...|  .. .. 
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS--------------------------FVCCPDEMYQIMKQC

LHFNPQKRLTAEQALQHPYVAQF
 |..| .| | ..      . .|
WHEDPEDRPTFSEI-----HECF
Kinase ERK7.AA Pkinase_Tyr 13-203 26 1.5e-13 46.5 Pfam 1-199 (270) Show / Hide 
Range on Protein: 13-203
Range on HMM: 1-199/270
Sequence Identity: 26% (54 aa)

YHVCQKLGKGAYGIVWKAFDR----KTNDVVALKKIFDAFQNSTD--AQRTFREVMFLQEINDHENVIKLTNVLKAENDR-DLYLVFEYMET-DLHAVIR
 .  .|||.||.| |.|.  .    .|.  || |..      . .   .  .||.  . .. .|.|...|  |   . .   .|.|.|||.  ||.   |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

AN-----ILEDVHKQYIMYQLFKSLKYLHSAGLLHRDIKPSNLLLDSDCRCKLADFGLARSVAQLKDDMG-QAQVLTDYVATRWYRAPEILLGSTNYTFG
..      |   ..  . .|  | . ||.| .. |||.   | |....  .| .|||||| .   .||   ...  .. .  .|. ||| .  .  .|  
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI--YNDDYYYRKRGGGK-LPIKWM-APECINYGK-FTTK

VDMWS
 | ||
SDVWS