Gene PEK-S1_p (S.moellendorffii)

PEK-S1_p

Species: S.moellendorffii
Alias: PEK-S1_p
External Links:
Annotation:

Classification

Group: Other
Family: PEK
Subfamily: PEK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
PEK-S1_p.AA Protein None 220 None Fasta, JSON
PEK-S1_p.NA RNA None 660 None Fasta, JSON
PEK-S1_p.kin_dom Protein Kinase Domain None 96 None Fasta, JSON

Protein domain

Protein domains of PEK-S1_p.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase PEK-S1_p.AA Pkinase 106-201 34 2.5e-25 90.63 Pfam 1-89 (293) Show / Hide 
Range on Protein: 106-201
Range on HMM: 1-89/293
Sequence Identity: 34% (33 aa)

YEVLACVGQGASGKVYKCRSKEDEQIYAIKVIKVRTATKSRDQDVALVFKEGEMLQRCEHPNIVKYFDMWKEEGEPGKSKVYIVMEFCGRSLQSVL
|... ..|.|..|.||||. | ...|.|.|.||.|.. .. ||  ..   | ....|. |||||...|.. .     |...|.|||.|.  |  |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWFED-----KDHIYMVMEYCEGGLY-VM
Kinase PEK-S1_p.AA STE20 106-194 33 1.6e-24 86.72 In-house 1-91 (288) Show / Hide 
Range on Protein: 106-194
Range on HMM: 1-91/288
Sequence Identity: 33% (31 aa)

YEVLACVGQGASGKVYKCRSKEDEQI----YAIKVIKVRTATKSRDQDVALVFKEGEMLQRCEHPNIVKYFDMWKEEGEPGKSKVYIVMEFCG
|| | ..|||..|||||.. |.  ..    .|||.......   . ... ...||  ....| |||||||..    . ..  .. .||||.||
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQ-DEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTC-DDELWIVMEYCG
Kinase PEK-S1_p.AA STE 106-201 22 2.3e-24 83.02 In-house 1-128 (359) Show / Hide 
Range on Protein: 106-201
Range on HMM: 1-128/359
Sequence Identity: 22% (29 aa)

YEVLACVGQGASGKVYKCRSKE---------------DEQIYAIKVIKVRTATKSRDQ-------------DVALVFKEGEMLQRCE--HPNIVKYFDMW
.| . ..|.||.|.|||.. ..                 .|.|||...... ...  .             ..  . || .....|   |||||||... 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

KEEGEP--GKSKVYIVMEFCG-RSLQSVL
  ||..   .....|.||...  || ...
FKEGHNHKNDDELWICMEYMDGGSLDDII
Kinase PEK-S1_p.AA CAMK 111-193 18 1e-21 66.15 In-house 1-142 (425) Show / Hide 
Range on Protein: 111-193
Range on HMM: 1-142/425
Sequence Identity: 18% (27 aa)

CVGQGASGKVYKCRSKEDE------------QIYAIKVIKVRTATKS-----------------------RDQDVALVFKEGEMLQRCE-------HPNI
  |.|. |||..|. |..             | .|||.|. . ....                       |..| . |..| |.....        ||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKYFDMWKEEG------EPG---------KSKVYIVM---EFC
.| ....  .       . .         ....|.||   |.|
IKLYEVYEDPHYFKNTND-YETSKQVFTKDKHMYMVMEIMEYC
Kinase PEK-S1_p.AA NEK 106-193 35 2.3e-20 68.7 In-house 1-88 (286) Show / Hide 
Range on Protein: 106-193
Range on HMM: 1-88/286
Sequence Identity: 35% (34 aa)

YEVLACVGQGASGKVYKCRSKEDEQI-----YAIKVIKVRTATKSRDQD--VALVFKEGEMLQRCEHPNIVKYFDMWKEEGEPGKSKVYIVMEFC
||..  .|||. |||||.|.|.|...     |..| |..   .    |.       .|   |..  |||||||.| . ||.   ... .||||.|
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQN----NEVRILKQLKHPNIVKYYDSFIEEQ---NNCLCIVMEYC
Kinase PEK-S1_p.AA CMGC 106-201 21 8.6e-20 60.87 In-house 1-145 (513) Show / Hide 
Range on Protein: 106-201
Range on HMM: 1-145/513
Sequence Identity: 21% (31 aa)

YEVLACVGQGASGKVYKCRS--------------KEDEQIYAIKVIKVRTATKSR-----DQDVAL--VFKEGEMLQRCE-----------------HPN
||..  .|.|. |.|||||               .|...|.||| || .   .         |.     . | ..|..                   |.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IVKYFDMWKEEGEPGKS------------KVYIVMEFCGRSLQSVL
||| .|. . ... |.             ..|.|.|... .|  ..
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYI
Kinase PEK-S1_p.AA KHS 106-200 38 2.8e-19 61.39 In-house 1-86 (258) Show / Hide 
Range on Protein: 106-200
Range on HMM: 1-86/258
Sequence Identity: 38% (37 aa)

YEVLACVGQGASGKVYKCRSKEDEQIYAIKVIKVRTATKSRDQDVALVFKEGEMLQRCEHPNIVKYFDMWKEEGEPGKSKVYIVMEFCGR-SLQSV
||.|  || |  | ||| | .. ... |.||||.       ..|.|.. .|  |.. |.||||| ||  .       . |..|.||.||  ||| .
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKMEP-----GDDFAVIQQEIMMMKDCRHPNIVAYFGSYLR-----RDKLWICMEYCGGGSLQDI
Kinase PEK-S1_p.AA NEK1 106-193 36 3e-19 63.55 In-house 1-82 (276) Show / Hide 
Range on Protein: 106-193
Range on HMM: 1-82/276
Sequence Identity: 36% (32 aa)

YEVLACVGQGASGKVYKCRSKEDEQIYAIKVIKVRTATKSRDQDVALVFKEGEMLQRCEHPNIVKYFDMWKEEGEPGKSKVYIVMEFC
|...  .|.|. ||... ..||| | |.|| |.|   .|. ...   . .|.  |.. .|||||||..   |.|       |||||.|
YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINV---MKMQEKEREESMNEVAILAKMKHPNIVKYKESFEENGC---GILYIVMEYC
Kinase PEK-S1_p.AA WEE 106-198 31 1.1e-18 59.32 In-house 1-95 (297) Show / Hide 
Range on Protein: 106-198
Range on HMM: 1-95/297
Sequence Identity: 31% (32 aa)

YEVLACVGQGASGKVYKCRSKEDEQIYAIKVI-KVRTATKSRDQDVALVFKEGEMLQ---RCE-HPNIVKYFDMWKEEGEPGKSKVYIVMEFCGRS---L
....  .|.| .|.|||||...| .|||||.. . .  ...|.. .  | .  . |     |. ||.||.|.  |.|     ... ||.||.| ..   |
FQEVQKIGEGSFGEVYKCRCRIDGCIYAIKKSKQPFRGYSERKRALREV-YAHMVLGQIMDCDHHPHIVRYYSAWEE-----DDHMYIQMEYCNGGSNLL

Q
|
Q
Kinase PEK-S1_p.AA CAMKL 106-194 22 1.8e-18 55.42 In-house 1-104 (297) Show / Hide 
Range on Protein: 106-194
Range on HMM: 1-104/297
Sequence Identity: 22% (24 aa)

YEVLACVGQGASGKVYKCRS-KEDEQIYAIKVIKVRTAT------------KSRDQDVALVFKEGEMLQRCE---HPNIVKYFDMWKEEGE--PGKSKVY
|...   |.|. |||  ..  .  .. .|||.|. . ..            |. ..|.  ...| . ...     ||||.| ....  .       .|.|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKH-ESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIET-KKIY

IVMEFCG
.||| |.
LVMEYCS
Kinase PEK-S1_p.AA RSK 109-193 35 6.9e-16 54.86 In-house 1-83 (278) Show / Hide 
Range on Protein: 109-193
Range on HMM: 1-83/278
Sequence Identity: 35% (32 aa)

LACVGQGASGKVYKCRSK---EDEQIYAIKVIKVRTATKS-RDQDVALVFKEGEMLQRCE-HPNIVKYFDMWKEEGEPGKSKVYIVMEFC
|   |||. |||. || .     .|||| ||.| ... .. .|  .. ...| . |.||. ||.||....  ..||     |.|..||.|
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKD--TRHTMTERNILERCQQHPFIVTLHYAFQTEG-----KLYLIMEYC
Kinase PEK-S1_p.AA S_TKc 106-220 17 5e-06 -88.14 SMART 1-220 (231) Show / Hide 
Range on Protein: 106-220
Range on HMM: 1-220/231
Sequence Identity: 17% (41 aa)

YEVLACVGQGASGKVYKCRSKEDEQIYAIKVIKVRTATKSRDQDVALVFKEGEMLQRCEHPNIVKYFDMWKEEGEPGKSKVYIVMEFCGR---SLQSVLL
||.|  .|.|| ||||||| |.. .|.|||.||              . .| ..|..  ||||||..|.. .      ...|.|||.|.    .| ... 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------------EHIRREIQILKK-HHPNIVKLYDVFQD------DHLYMVMEYCDGDLGDLFDYIK

G-----------------------------------------------------------------------------GE--------------------
                                                                              |                     
KRGRHGLRFPFPEHARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQLTTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLCGYP

--------------SPPADAFRQLLQ----------AVA
              ..  |  |..||          | .
PFPQMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTAEALQ
Kinase PEK-S1_p.AA Pkinase_Tyr 106-193 26 2.7e-05 18.58 Pfam 1-89 (270) Show / Hide 
Range on Protein: 106-193
Range on HMM: 1-89/270
Sequence Identity: 26% (25 aa)

YEVLACVGQGASGKVYKCRSK----EDEQIYAIKVIKVRTATKSRDQD--VALVFKEGEMLQRC-EHPNIVKYFDMWKEEGEPGKSKVYIVMEFC
 . .   |.|| |.|||.. |    ....  |.|..|     .. ...   .  ..| ...     |||||..     ..|||.  ..|||||..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE----GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN--QIYIVMEYM