Gene TLK-2 (S.moellendorffii)

TLK-2

Species: S.moellendorffii
Alias: TLK-2
External Links:
Annotation:

Classification

Group: Other
Family: TLK

Sequence

Name Sequence Type Origin Length Description Download
TLK-2.AA Protein None 645 None Fasta, JSON
TLK-2.NA RNA None 1938 None Fasta, JSON
TLK-2.kin_dom Protein Kinase Domain None 274 None Fasta, JSON

Protein domain

Protein domains of TLK-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase TLK-2.AA TLK 365-638 60 1.1e-181 609.91 In-house 1-285 (285) Show / Hide 
Range on Protein: 365-638
Range on HMM: 1-285/285
Sequence Identity: 60% (172 aa)

YALLNLLGKGGFSEVYKAYDMVEYRYVACKLHGLNVQWSEEKKQNYIRHAIREYNIHKSLVHSHIVRLWDIFEIDHNTFCTVLQYCGGKDLDAVLKSTSV
| ||.|||||||||||||.|. | |||||| | ||  |.||||.||| ||.|||.|||.| |  ||.| |.|||| |.|||||.|| | |||  ||  ..
YQLLHLLGKGGFSEVYKAFDLHEFRYVACKIHQLNKNWKEEKKANYIKHACREYKIHKELDHCRIVKLYDYFEIDNNSFCTVLEYCEGNDLDFYLKQHKT

LPEREARSIMVQIFSGLVYLNRRSQRVIHYDLKPGNVLFDEA---GAAKLTDFGLSKIVEDEVGS--QGMELTSQGAGTYWYLPPECFDVNK------TP
.||.|||.|  || . |.||| .. ..|||||||.|..| .    |. |.|||||||| .||     .|||||||||||||||||||| | |       |
MPEKEARCIIMQIVCCLKYLNEIKPPIIHYDLKPQNIIFHKGNTCGEIKITDFGLSKIMDDEQYRHDHGMELTSQGAGTYWYLPPECFVVGKCEEFENPP

LISSKVDVWSAGVLFYQMLFGKRPFGHDQSQERILREDTITKARKVEFPTRPSVSADAKDFIRRCLSYDQMDRPDVLTAAQDPYL
.||.|||||| || |||.|.|..||||..||. ||.. || ||. |.||  |.||  .|||||||| |.| || ||  ....||.
KISCKVDVWSVGVIFYQCLYGQKPFGHNMSQQQILEQNTILKATEVQFPSKPQVSNECKDFIRRCLQYRQEDRWDVQQLWNHPYM
Kinase TLK-2.AA S_TKc 365-638 30 1.2e-74 255.17 SMART 1-231 (231) Show / Hide 
Range on Protein: 365-638
Range on HMM: 1-231/231
Sequence Identity: 30% (88 aa)

YALLNLLGKGGFSEVYKAYDMVEYRYVACKLHGLNVQWSEEKKQNYIRHAIREYNIHKSLVHSHIVRLWDIFEIDHNTFCTVLQYCGG--KDLDAVLKST
| .|...|||.|..|||...    |.||.|                 .|..|| .|.|.  | .||.| |.|.   . .. |. ||.|   ||  ..|. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKR

SV------LPEREARSIMVQIFSGLVYLNRRSQRVIHYDLKPGNVLFDEAGAAKLTDFGLSKIVEDEVGSQGMELTSQGAGTYWYLPPECFDVNKTPLIS
        .|| .||..| ||...| |. ..  ..|| |||| |.|.||    |..||||....            .   || ||..|| .        .
GRHGLRFPFPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE--HIKICDFGLARQL------------TTFCGTPWYMAPEVL------GYG

S-KVDVWSAGVLFYQMLFGKRPFGHDQSQERILREDTITKARKVEFPTRPSVSADAKDFIRRCLSYDQMDRPDVLTAAQ-------DPYL
  |.|.|| |...| || |. ||     |.  . .                 | .||||||.|| .|  .|| .  | |       .|..
KCKCDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase TLK-2.AA Pkinase 365-638 27 4.7e-61 213.96 Pfam 1-293 (293) Show / Hide 
Range on Protein: 365-638
Range on HMM: 1-293/293
Sequence Identity: 27% (85 aa)

YALLNLLGKGGFSEVYKAYDMVEYRYVACKLHGLNVQWSEEKKQNYIRHAIREYNIHKSLVHSHIVRLWDIFEIDHNTFCTVLQYCGGK----DLDAVLK
| ..  .|.|.|..|||...  . . ||.|   ....  ...|. . |.. .|  |.|.| | .||||.|.||  ..  . |. ||.|     || ....
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKI--IKKRHEKSWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYIS

--STSVL--PEREARSIMVQIFSGLVYLNRRSQRVIHYDLKPGNVLFDEAGAA----KLTDFGLSKIVEDEVGSQGMELTSQGAGTYWYLPPECFDVNKT
  .  ..  .|.|....| ||..|| |. ..  ..|| |||| |.|.|. |      |..||||.| ..        . ..  .||.||..||   ... 
TWRHGCFYFSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----Y-NNS-MTTFCGTPWYMAPEV--IRGG

PLISSKVDVWSAGVLFYQMLFGKRPFGHD-----QSQERILREDTITKARKVEFPTRP----------------SVSADAKDFIRRCLSYDQMDRPDVLT
. ...|||.||.|...|.||.|. || ..      .|  .....  .. .  .. ...                 .| ..||||..|| .|  .||    
QYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQ

AAQDPYL
. |.|..
ILQHPWF
Kinase TLK-2.AA Ciliate-E2-Unclassified 365-638 21 1.9e-54 187.2 In-house 1-352 (352) Show / Hide 
Range on Protein: 365-638
Range on HMM: 1-352/352
Sequence Identity: 21% (77 aa)

YALLNLLGKGGFSEVYKAYDMVEYRYV-----ACKLHGLNVQWSEEKKQNYIRHAIREYNIH-------------KSLVHSHIVRLWDIFEI-DHNTFCT
| ..  .|.|||..|||...  .. ..     ..| .  ...  ..|. .... .... |.                | | |.... ....  | .... 
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VLQYCGGKDLDAVLKSTSV-----------------LPEREAR-----SIMVQIFSGLVYLNRRSQRVIHYDLKPGNVLFDEAG---AAKLTDFGLSKIV
|..|| |.||   .|. .                  ..|..|.      .. || .|| || .    .||.|.|| |.|||. |     |..|||.||  
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKN-NIIHRDIKPENILFDNNGKNYYIKIIDFGISKKY

EDEVGSQGMEL-----------TSQGAGTYWYL----PPECFDVNKTPLISS-KVDVWSAGVLFYQMLFGKRPFGHDQSQE------------RILREDT
.. ....  .            ... .||. |.    .||... ..    .. |.|.|| ||..|.||||..||.  .. .            ...    
QQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQ

ITKARKVEFPTRP------SVSADAKDFIR----RCLSYDQMDRPDVLTAAQDPYL
. |.....||  |       .|  |||||.    ..| ...  |..   . . |..
NIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase TLK-2.AA Ciliate-E2 365-638 21 8.4e-53 179.57 In-house 1-365 (365) Show / Hide 
Range on Protein: 365-638
Range on HMM: 1-365/365
Sequence Identity: 21% (83 aa)

YALLNLLGKGGFSEVYKAYDMVEYRYVA----------------CKLHGLNVQWSEEKKQNYIRHAIREYN-------------IHKSLVHSHIVRLWDI
| .....|.|.|. |||. .  . . .|                .|    ..   .... ..|   |....             | ..| | .|... . 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE-IDHNTFCTVLQYCGGKDLDAVLK-----STSVLP------EREARSIMVQIFS---------------GLVYLNRRSQRVIHYDLKPGNVLFDEAGA
|. .| |..  |. || |.||   .|     ... ..      |.|.. || ||..               .| ||  .   .|| |.|| |.||     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN-IIHRDIKPENILF-----

AKLTDFGLSKIVED------EVGSQGMELTSQG----------------------AGTYWYLPPECFDVNK------TPLISSKVDVWSAGVLFYQMLFG
 |..||||||.. |      . ..|  ...  .                      .||. |..|| .   |          . |.|.||.||..|.||||
IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

KRPFGHDQSQERILREDTITKARKVEFP----------------TRPSVSADAKDFIRR----CLSYDQMDRPD-VLTAAQDPYL
|.||              . |  |..||                   ..| ..||.|..    .| .|.  |..    . . |..
KPPF------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase TLK-2.AA CAMK 370-638 17 9.1e-52 164.7 In-house 1-425 (425) Show / Hide 
Range on Protein: 370-638
Range on HMM: 1-425/425
Sequence Identity: 17% (76 aa)

LLGKGGFSEVYKAYDM-VE-----------YRYVACKL--------------------HGLNVQWSEEK-KQNYIRHAIREYNIHKSLV-------HSHI
 ||.|.|..|.....                . ||.|                        ........ ...  .   ||..|.|.|        | .|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRLWDIFEIDHNT------------------FCTVL---QYCGGK----D-LDAVLKSTS--------------VLPEREARSIMVQIFSGLVYLNRRSQ
..| ...| .|..                  .. |.    || |     | .| . . ..               ..||||| .. || |.. |.   |.
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYC--HSH

RVIHYDLKPGNVLFDEA-----------------GAAKLTDFGLSKIVEDEVGSQG------------------MELTSQGAGTYWYLP-PECFDVNK--
 ..| |||| |.|.|.                  .  |..|||.......  ..                     .. .   ||  | . || .  ..  
NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

---------TPLISSKVDVWSAGVLFYQMLFGKRPFGHD------------QSQERILREDTITKARKVEFP--------------------TRPSVSAD
          | .. |.|.||.||. | || |. || .|            ........  .  | .  ...                    ..  ||..
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH-FVSQE

AKDFIRRCLSYDQMDRPDVLTAAQDPYL
.||.||..| .|  .|. .  . ..| .
CKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase TLK-2.AA ULK 365-626 28 1.6e-48 167.5 In-house 1-312 (324) Show / Hide 
Range on Protein: 365-626
Range on HMM: 1-312/324
Sequence Identity: 28% (93 aa)

YALLNLLGKGGFS-EVYKAYDMVE---YRYVACKLHGLNVQ---WSEEKKQ---NYIRHAIR-EYNIHKSLV---HSH--IVRLWDIFEIDH-NTFCTVL
| | . |||| |   |||....       |||||     ..    .. |..   .|.   .. | .| | |    | .  ||.| |.|| .. | .. ..
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKM----IDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIM

QYCGGKDLDAVLKST---------SVLPEREARSIMVQIFSGLVYLNRRSQRVIHYDLKPGNVLFDEA------------GAAKLTDFGLSKIVED-EVG
 || | ||.  .|             |.| ||.... || .|. .|  ... .|| |.|| | |  .             | .|..|||..|.|.. .  
EYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKEL--HKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNME

SQGM-----ELTSQGA---GTYWYLPPECFDVN--KTPLISSKVDVWSAGVLFYQMLFGKRPFGHD-QSQE----RILRE----DTITKARKVEFPTRP-
 | .     |         ||  |  |. .  .  . |  ..|.|.|| |..||.||.|| ||  . ..|.    . ..      .. | ....||  | 
QQMCQTCVNE-----KRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPK

--SVSADAKDFIRRCLSYDQMDR
   .| . ||.|||.| ||. ||
DPKISPECKDLIRRMLQYDEKDR
Kinase TLK-2.AA ULK 365-626 28 2.7e-48 166.69 In-house 1-317 (329) Show / Hide 
Range on Protein: 365-626
Range on HMM: 1-317/329
Sequence Identity: 28% (91 aa)

YALLNLLGKGGFSEVYKAYDMVE----YRYVACKLHGLNVQWSEEKKQ--NYIRHAIR-EYNIHKSLV--------HSHIVRLWDIFEIDH-NTFCTVLQ
| | . |||| |  |||....        .||||   .. .  ... |  .|.   .. |  | | |         | .||.| |.|| .. | .  .. 
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCGGKDLDAVLKST----------SVLPEREARSIMVQIFSGLVYLNRRSQRVIHYDLKPGNVLFDEA------------GAAKLTDFGLSKIVEDE-VG
|| | ||.  .|              |.| ||.... || .|. .|  .....|| |.|| |.| ..             | .|..|||..| |... . 
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKEL--HKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNME

SQGMELTS-QGA---GTYWYLPPECFDVN--KTPLISSKVDVWSAGVLFYQMLFGKRPFGHDQSQERI------LREDTITKA-----RKVEFP---TRP
 | |  .. .     ||  |  |. .  .  . |  ..|.|.|| |..||.||.|| ||     .. .      |.... . .     .. .||     |
QQMMMTCVNE-KRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDP

SVSADAKDFIRRCLSYDQMDR
 .| . ||.|||.| ||. ||
QISPECKDLIRRMLQYDEKDR
Kinase TLK-2.AA CAMKL 365-638 28 2.2e-41 129.7 In-house 1-297 (297) Show / Hide 
Range on Protein: 365-638
Range on HMM: 1-297/297
Sequence Identity: 28% (87 aa)

YALLNLLGKGGFSEVYKAYD-MVEYRYVACKLHGLNVQWSEEKKQNY-----------IRHAIREYNIHKSLV---HSHIVRLWDIFEIDHN-----TFC
| ..  ||||.|..|  | . .   . || |    .  | ......            ||   ||..|.|.|    | .|..| ...| . .      ..
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIR---REIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIY

TVLQYCGGKD--LDAVLKST----SVLPEREARSIMVQIFSGLVYLNRRSQRVIHYDLKPGNVLFDEAG--AAKLTDFGLSKIVEDE-VGSQGMELTSQG
 |. ||.| .  |   ...       .||.||| .  || |.. |.   |....| |.|| |.|.|| |   .|..|||.| . ..  .|.  .  |.  
LVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYC--HSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFC-

AGTYWYLPPECFDVNKTPLISSKVDVWSAGVLFYQMLFGKRPFGHD----QSQERILREDTITKARKVEFPTRPSVSADAKDFIRRCLSYDQMDRPDVLT
 |.. | .|| |  |..| .  |||.||.||. | |..|. ||  |    | .. | ..  ...    ..|  ..|| |..|.||. |  . ..|| .  
-GSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQ

AAQDPYL
  ..| .
IMNHPWM
Kinase TLK-2.AA TKL 371-627 18 1.4e-35 124.52 In-house 1-355 (364) Show / Hide 
Range on Protein: 371-627
Range on HMM: 1-355/364
Sequence Identity: 18% (67 aa)

LGKGGFSEVYKAYDMVEY--------RYVACK-LHGLNVQWSEEKKQN-------------------YIRHAIREYNIHKSLVHSHIVRLWDIFEIDHNT
.|.|||.||||.. . .         . || | ..  |.. .... |.                   .  . ..| .....| | .||..  .     ..
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------FCTVLQYCGGKD-LDAVLKSTSVLPEREARSIMVQIFSGLVYLNRRS------QRVIHYDLKPGNVLFDEAGA--------------A
            .| | .|| | . |. ..            ... .| .|. ||  .         .|| |||. |.| || .               .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KLTDFGLSKIVEDEVGSQGME--------------LTSQGAGTYWYLPPECFDVN-------------KTPLISSKVDVWSAGVLFYQMLFGKRPFGHDQ
|..|||||. .. . ... ..               |.   ||. ...||... .             |    | |.||.| |.... .| ..||. .. 
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

SQERILR-------EDTITKARKVEFPTR----------PSVSADAKDFIRRCLSYDQMDRP
. ..|..       .  . | .. . |..          |..  . |. . .| ..|  .||
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRP
Kinase TLK-2.AA STE 365-638 19 3e-35 121.93 In-house 1-359 (359) Show / Hide 
Range on Protein: 365-638
Range on HMM: 1-359/359
Sequence Identity: 19% (72 aa)

YALLNLLGKGGFSEVYKAYDMV---------------EYRYVACKLHGLNVQWSEEKK-----------QNYIRHAIREYNIHKSLV--HSHIVRLWDIF
. ..  .|||.| .||||...                  ...| |   |. . ... .           .. .   ..| .|.| .   | .||.  . .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

EID------HNTFCTVLQYCGGKDLDAVLKST--------------SVLPEREARSIMVQIFSG-LVYLNRRSQRVIHYDLKPGNVLFDEAGAAKLTDFG
. .      ... . .. |..|  || ..|..              ...|| . . | .||  | | || .    .|| |.||.|.|.     .||.|||
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH--IIHRDIKPANILL-----VKLCDFG

LSKIVEDEVG------------SQG-MELTSQGAGTYWYLPPECFDVNKTP---LISSKVDVWSAGVLFYQMLFGKRPF---GHDQSQERILRE------
......|..             ... .  |  |     .  ||  . |...     . |.|.|| | .   |. || |.    . .   .|...      
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP---WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQ

-DTITKARKVEFPTRPS--------------------VSADAKDFIRRCLSYDQMDRPDVLTAAQ--DPYL
 . . .  . . |. |.                    .| . ||||..|| .|  .||..    .   | .
FEQL-CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase TLK-2.AA CMGC 365-578 18 3.2e-33 105.81 In-house 1-342 (513) Show / Hide 
Range on Protein: 365-578
Range on HMM: 1-342/513
Sequence Identity: 18% (65 aa)

YALLNLLGKGGFSEVYKAYD--------------MVEYRYVACK--LHGLNVQWSEE---KKQNYIRHAIREYNIHKSLV-----------------HSH
|  .. .|.| ...|||..|              .   ..|| |        .. .    .| .  . |.||  | | |                  | .
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IVRLWDIFEIDH----------------NTFCTVLQYCGGKDLDAVLKSTS---------VLPERE------------ARSIM------VQIFSGLV--Y
||.| |||  ..                | .. |  |. ..||  ..|...          |.| .             ...|       ||. ||   |
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYM-DHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKY

LNRRSQRVIHYDLKPGNVLFDEAGAA--------------------KLTDFGLSKIVEDEVGSQG----------------MELTSQGAGTYWYLPPECF
. ..  ..|| |||| |.|... .                      |. ||||....... .  .                ..  ..   | || .||  
CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEIL

DVNK-------TPLISSKVDVWSAGVLFYQMLFG-------KRPF
   |       .   ....|.||.|  |. |. |       ..|.
LGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPL
Kinase TLK-2.AA TyrKc 365-636 23 3.7e-12 -26.11 SMART 1-280 (280) Show / Hide 
Range on Protein: 365-636
Range on HMM: 1-280/280
Sequence Identity: 23% (69 aa)

YALLNLLGKGGFSEVYKAYDMVEYRYVACKLHGLNVQWSEEKKQNYIRHAIREYNIHKSL--VHSHIVRLWDIFEIDH------NTFCTVLQYCGGKDLD
  |.  || | | ||||.      . || |    .           ..  .|| .| ..|   | .||||  .   .          . |. |. . ||.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLK

AVLKSTSV-LPEREARSIMVQIFSGLVYLNRRSQRVIHYDLKPGNVLFDEAGAAKLTDFGLSKIVEDE--VGSQGMELTS----QGA--GTYWYLPPECF
  |...   |. ..  |...|| .|  || ..  ..|| ||   |.| .| . .| .|||||. ..|.   |  .   ..    .|     .  ..|||.
DYLRKHRPKLCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

DVNKTPLISSKVDVWSAGVLFYQML-FGKRPFGHDQSQERILREDTITKARKVEFPTRPSV---------SADAKDFIRRCLSYDQMDRPDVLTAAQDP
   ..   ..| |||| ||. . .. .|. |   .  |  .  .. | . .. . . .|           ...  . ...|  .|  |||   .  .. 
---NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase TLK-2.AA CMGC 608-638 32 1.1e-05 13.64 In-house 483-513 (513) Show / Hide 
Range on Protein: 608-638
Range on HMM: 483-513/513
Sequence Identity: 32% (10 aa)

SADAKDFIRRCLSYDQMDRPDVLTAAQDPYL
. .| |.. ..| ||  .|. .  | | ||.
DPQAIDLLKKMLQYDPDKRITAEQALQHPYF