Gene ULK_a (S.moellendorffii)

ULK_a

Species: S.moellendorffii
Alias: ULK_a
External Links:
Annotation:

Classification

Group: Other
Family: ULK
Subfamily: ULK

Sequence

Name Sequence Type Origin Length Description Download
ULK_a.AA Protein None 530 None Fasta, JSON
ULK_a.NA RNA None 1593 None Fasta, JSON
ULK_a.kin_dom Protein Kinase Domain None 269 None Fasta, JSON

Protein domain

Protein domains of ULK_a.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc ULK_a.AA S_TKc 7-275 34 7.9e-95 322.26 SMART 1-231 (231) Show / Hide 
Range on Protein: 7-275
Range on HMM: 1-231/231
Sequence Identity: 34% (98 aa)

YRLLHKIGVGSFATVWKAMHKITGEIVAIKVIVPRMDQLRQQLELIAQEQAIMKSIAHPNVVKLLGMISEDEHDELSTRYLVMEFCEG--GDLDHYIHLN
|..| ||| |.|..|.|. || ||.|||||.|           | | .| .|.|.  |||.|||.... .      .  |.|||.|.|  ||| .||. .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD------DHLYMVMEYCDGDLGDLFDYIKKR

KK------LSAGVARTIMLQLSAALQELRRMNLIHRDLKPHNLLLKNKVAPGSDPEGEEIVVKLTDFGLARKLQPQGMAQTMCGTYLYMAPEVISHNKYD
..      ..  .|| .| |.  ||. . ... ||||||| |.|| .             ..|..||||||.|       |.|||  ||||||.   .|.
GRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------------HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYG

A-KADLWSVGVMLYQMITGRRPFEACSSEDLFRKLGNKVQFRGEDCWDPDCRDLCEGLLRKNPLERISFEEFFN-------HKFL
  |.| ||.|..|| |..|. ||.    . .|.|.|           .|...|. ...|.|.| .|..  | ..       | ..
KCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase ULK_a.AA ULK 7-275 30 1.6e-92 313.7 In-house 1-324 (324) Show / Hide 
Range on Protein: 7-275
Range on HMM: 1-324/324
Sequence Identity: 30% (102 aa)

YRLLHKIGVGSFA-TVWKAMHKIT---GEIVAIKVIV---PRMDQLRQQ----LELIAQEQAIMKSIA---HPN--VVKLLGMISEDEHDELSTRYLVME
| | |..| |||. .| |. .|.|   ...||.|.|     ......|.    ..|. .|  ||| .    |||  .|||. .  .. |      |..||
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNH---NNIYIIME

FCEGGDLDHYIHLNKKLSAGV----------ARTIMLQLSAALQELRRMNLIHRDLKPHNLLLKNKVAPGSDPEGE---EIVVKLTDFGLARKLQPQGMA
.|.||||..||. ||||.  .          |. .. |. ....||. .| ||||.|| |.|..|...   | . .   ..|.|..|||.|....  .|.
YCNGGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKT-DSK-KVHPNGVLKIADFGFAKHVDNNNME

QTMC----------GTYLYMAPEVIS----HNKYD-AKADLWSVGVMLYQMITGRRPFEACSSEDLF----RKLGN-----------KVQFR---GEDCW
|.||          || |||||....    . .|. .|.|.||.|...|.|..|. ||...  .|..    . . |           ..||.    ..  
QQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKI

DPDCRDLCEGLLRKNPLERISFEEFFNHKFL
 |.|.||  ..| ... .|||.||.|||...
SPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase ULK_a.AA AGC 7-275 22 9.2e-90 231.54 In-house 1-395 (395) Show / Hide 
Range on Protein: 7-275
Range on HMM: 1-395/395
Sequence Identity: 22% (92 aa)

YRLLHKIGVGSFATVWKAMHK------ITGEIVAIKVIVPRM-DQLRQ--QLELIAQE------------QAIMKSIA----------HPNVVK-LLGMI
...|  || ||| .|. . .|       ||.. |.||.  .   ....  ..| .  |              |.. .           ||..|| |    
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

SEDEHDELSTRYLVMEFCE--------GGDLDHYIHLNK-----KLSAGVARTIMLQ-------LSAALQELRR-MNLIHRD-LKPHNLLLKNKVAPGSD
  ..|. |   |.|||...        ||... ..|| .     ...  .|| .. .       .  ||. | . |. |||| ||| |.|| ..      
QDKDHTYL---YFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDED------

PEGEEIVVKLTDFGLARKLQPQG---------------------------------------------------MAQTMCG--TYLYMAPEVISHNKYDA
       .|||||||. ..   |                                                   ...|.||  |  |||||..    |. 
-----GHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGK

KADLWS--VGVMLYQMITGRRPFEACSSE----------DLFRKLG-------NKVQFR--------GEDCWDPDCRDLCEGLLRKNPLERIS-------
 .| ||  .|...|.|.||. || . . .          ..| |         .||.|         ... ..|...||...|| |.| .|.        
ACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFG

---FEEFFNHKFL
   .||  ||.. 
DKGAEEIKNHPWF
Kinase ULK_a.AA ULK 7-275 31 1.4e-87 297.31 In-house 1-329 (329) Show / Hide 
Range on Protein: 7-275
Range on HMM: 1-329/329
Sequence Identity: 31% (104 aa)

YRLLHKIGVGSFATVWKAMHKIT----GEIVAIKVIV---PRMDQLRQQ----LELIAQEQAIMKSIA--------HPNVVKLLGMISEDEHDELSTRYL
| | |..| |||..| |. .|.|    .|.||.|.|     ....  |.    ..|. .|  ||| .         |||.|||. .  .. |. .   |.
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNI---YI

VMEFCEGGDLDHYIHLNKK----------LSAGVARTIMLQLSAALQELRRMNLIHRDLKPHNLLLKNKVAPGSDPEGE---EIVVKLTDFGLARKLQP-
.||.|.||||..||. |||          ||   |. .. |. ....||. .| ||||.|| | |..|...   | . .   ..|.|..|||.|....  
IMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKT-DSK-KVHPNGVLKIADFGFAKHVDND

---QGMAQTMC------GTYLYMAPEVIS----HNKYD-AKADLWSVGVMLYQMITGRRPFEACSSEDLF-----RKLGNK-----------VQFR---G
   | |..|.       || |||||....    . .|. .|.|.||.|...|.|..|. ||.|.  .|..     . . |.            ||.    
NMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGN

EDCWDPDCRDLCEGLLRKNPLERISFEEFFNHKFL
..   |.|.||  ..| ... .|||.||.|||...
DPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase ULK_a.AA Pkinase 7-275 31 9.1e-86 296.04 Pfam 1-293 (293) Show / Hide 
Range on Protein: 7-275
Range on HMM: 1-293/293
Sequence Identity: 31% (96 aa)

YRLLHKIGVGSFATVWKAMHKITGEIVAIKVIVPRMDQLRQQLELIAQ--EQAIMKSIAHPNVVKLLGMISEDEHDELSTRYLVMEFCEGG----DLDHY
|... ||| |||..|.|..|| ||.|||.|.|  | ..  ....  .   | .|||.. |||.|.|...  .  .|..    .|||.||||    || .|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIY---MVMEYCEGGLYVMDLFDY

IH--LNKKL--SAGVARTIMLQLSAALQELRRMNLIHRDLKPHNLLLKNKVAPGSDPEGEEIVVKLTDFGLARK--LQPQGMAQTMCGTYLYMAPEVIS-
|.   ....  |  ... .|.|.  .|. . .|. ||||||| |.|..|.  ...        ||..|||||..  . ... ..| |||. |||||||  
ISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA-------CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRG

HNKYDAKADLWSVGVMLYQMITGRRPFEAC----SSEDLFRKLGNKVQFRGEDCWD-----------------------PDCRDLCEGLLRKNPLERISF
...|. |.| ||.|..||.|..|| ||  .    .  |   .. .. . . .  |.                       ..|.|.....|.|.| .|...
GQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTA

EEFFNHKFL
|. ..|...
EQILQHPWF
Kinase ULK_a.AA CAMK 12-275 21 1.6e-77 249.2 In-house 1-425 (425) Show / Hide 
Range on Protein: 12-275
Range on HMM: 1-425/425
Sequence Identity: 21% (95 aa)

KIGVGSFATVWKAMHKITG------------EIVAIKVIVPR---------------MDQL----------RQQLELIAQEQAIMKSIA-------HPNV
..| |||..| ...|| |.            . ||||.|  .               .|             . .. . .| .|||..        |||.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKLLGMISEDEH-------DELST--------RYLVM---EFCEGG----DLDHYIHLN---------------KKLSAGVARTIMLQLSAALQELRRMN
.||. ..  ...       .  |.         |.||   |.|.||    ||  ||  .               ....   ||... |.  |.. .  .|
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

LIHRDLKPHNLLLKNK------------VAPGSDPEGEEIVVKLTDFGLARKLQPQG------------------------MAQTMCGTYLYMA-PEVIS
 .|||||| |.|| ..              .     ..   .|..|||.|.|..|                          . .|.|||  ||| |||..
IVHRDLKPENILLDDNNDDSDPVEHDEIF-D-----WNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLN

H--------------NKYDAKADLWSVGVMLYQMITGRRPFEAC-------------SSEDLFRKLGNKV-QFR-----------GEDCWD---------
                 |. |.| ||.||.|| | .|. ||..              . ..||.|  .   .|            |.. ||         
GKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHF

--PDCRDLCEGLLRKNPLERISFEEFFNHKFL
  ..|.||  ..|...| .|.. |.  ||...
VSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase ULK_a.AA Ciliate-E2 7-275 24 2.7e-74 253.14 In-house 1-365 (365) Show / Hide 
Range on Protein: 7-275
Range on HMM: 1-365/365
Sequence Identity: 24% (95 aa)

YRLLHKIGVGSFATVWKAMHKITGE-----------------------IVAIKVIVPRMDQLRQQLELIA----------QEQAIMKSIAHPNVVKLLGM
| .. ||| |.|..|.|. .. ...                       |.|.|.. ... .   | . |           .|. |.... |||..|.   
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

ISE-DEHDELSTRYLVMEFCEGGDLDHYIHLN-----------KKLSAGVARTIMLQLSA---------------ALQELRRMN-LIHRDLKPHNLLLKN
  | |..    . |||||.|.|||| .||  |           |...   ...|| |.                 ||..|   |  ||||.|| |.|.  
FQEKDDN----NIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF--

KVAPGSDPEGEEIVVKLTDFGLARKLQPQ--------------------------------GMAQTMCGTYLYMAPEVISHNK---------YDAKADLW
              .|..||||..|....                                 |..| |||. |||||...  |         || |.|.|
--------------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIW

SVGVMLYQMITGRRPFEACSSEDLFRKLGNKVQFRGEDC----------------WDPDCRDLCEG----LLRKNPLERIS-FEEFFNHKFL
|.||.||.|..|..||       .  .. .|..|. ...                |...| ||.      .| |.| .||. .|. .||...
SLGVILYEMLFGKPPF-------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase ULK_a.AA CAMKL 7-275 30 8.2e-74 234.9 In-house 1-297 (297) Show / Hide 
Range on Protein: 7-275
Range on HMM: 1-297/297
Sequence Identity: 30% (93 aa)

YRLLHKIGVGSFATVWKAMH-KITGEIVAIKVIV---PRMDQLRQQLEL---------IAQEQAIMKSIA---HPNVVKLLGMISEDEH--DELSTRYLV
||..  .| |||..|  |.| ..||| ||||.|     ..|.  ..  .         | .| .|||..    |||..||. .|  .||  .  .  |||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIET-KKIYLV

MEFCEGGD--LDHYIHLN----KKLSAGVARTIMLQLSAALQELRRMNLIHRDLKPHNLLLK-NKVAPGSDPEGEEIVVKLTDFGLARKLQP-----QGM
|| |.||.  | .||  .    .... . || .  |. .|.. . ... .|||.|| |.||  |.            ..|..|||.. . .|       .
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN----------NIKIIDFGFSNMYRPCIFGPGQK

AQTMCGTYLYMAPEVISH--NKYD-AKADLWSVGVMLYQMITGRRPFEACS-------SEDLFRKLGNKVQFR-GEDCWDPDCRDLCEGLLRKNPLERIS
  | ||.. |||||...    .||  |.| || ||.|| |..|. ||.. .          ....  ..  ..    .  .|||||  ..| .|| .|..
LKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPT

FEEFFNHKFL
 ..  ||...
IHQIMNHPWM
Kinase ULK_a.AA Ciliate-E2-Unclassified 7-275 25 1.5e-67 230.72 In-house 1-352 (352) Show / Hide 
Range on Protein: 7-275
Range on HMM: 1-352/352
Sequence Identity: 25% (91 aa)

YRLLHKIGVGSFATVWKAMHKITGEIVAIKVIVPRMDQL-----RQQLELIAQEQAIMKS----------------IAHPNVVKLLGMISEDEHDELSTR
|.....|| |.|..|.|. || .... |.| .   ...      ... |.. .......                 . ||. ...  .  .   . .   
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNI---

YLVMEFCEGGDLDHYIHLNKK-----------------LSAGVAR-----TIMLQLSAALQELRRMN-LIHRDLKPHNLLLKNKVAPGSDPEGEEIVVKL
|.|||.||||||  ||  .||                 ..   |.     ... |.  .|. | . |  ||||.|| |.|..|.             .|.
YIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK--------NYYIKI

TDFGLARKLQ----------------PQGMAQTMCGTYLYM----APEVISHNKYD----AKADLWSVGVMLYQMITGRRPFEACSSED-----------
.|||...|.|                .| |..|.|||. ||    ||||.  ..||     |.| ||.|| ||.|..|..||.. ..|.           
IDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINN

-----LFRKL-GNKVQFRGEDC------WDPDCRDLCE----GLLRKNPLERISFEEFFNHKFL
     |...   ...||. ..       |.| . |...     .| ||| .||.||. .|| ..
AYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase ULK_a.AA Ciliate-E2a 7-275 32 3.2e-65 190.94 In-house 1-275 (275) Show / Hide 
Range on Protein: 7-275
Range on HMM: 1-275/275
Sequence Identity: 32% (94 aa)

YRLLHKIGVGSFATVWKAMHKITGEI-VAIKVIVPRMDQLRQQLELIAQEQAIMKSIAHPNVVKLLGMISEDEHDELSTRYLVMEFCEGGDLDHYIHLNK
|... ||| |.|. | .| ||.||.  ...|.|  .| |  .. | . .| .||... |||. || . . |||.    . |||||.||||.| ..|  .|
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYE-VYEDEN----NYYLVMEYCEGGELYDKIKQCK

KLSAG--VARTIMLQLS-AALQELRRMNLIHRDLKPHNLLLKNKVAPGSDPEG-EEIVVKLTDFGLARKL--QPQGMAQTMCGTYLYMA------PEVIS
..     ... || ||   .|. .   | .|||||| |.|.||      .... .   .|. |||||..     .    ..|||  |.|      .||..
RFFEEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKN-----CSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLK

HNKYDAKADLWSVGVMLYQMITGRRPFEACSSEDLFRKLGN-KVQFRGED---CWDPDCRDLCEGLLRKNPLERISFEEFFNHKFL
|..|| | |.||.||..| ...|. ||.. . .. . .  . | .| . .   . . .| ||  ..| |.| .||. ..  ||.. 
HKQYDTKCDMWSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase ULK_a.AA STE 7-275 23 4.8e-64 219.1 In-house 1-359 (359) Show / Hide 
Range on Protein: 7-275
Range on HMM: 1-359/359
Sequence Identity: 23% (90 aa)

YRLLHKIGVGSFATVWKAMHKI---------------TGEIVAIKVIVPRMDQL--------------RQQLELIAQEQAIMKSIA--HPNVVKLLGMIS
.... ||| |.| || |||..                ||||.|||..  . ..                .... | .|  |||     |||.|| .|.  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EDE--HDELSTRYLVMEFCEGGDLDHYIH--------LN------KKLSAGVARTIMLQLSAA-LQELRRMNLIHRDLKPHNLLLKNKVAPGSDPEGEEI
 .   |.. .. ...||...|| ||  |.        ||      ....  . ..|  |.  . |. | ... ||||.|| | ||               
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL---------------

VVKLTDFGLARKLQP-----------------QGMAQTMCGTYLYMAPEVISH------NKYDAKADLWSVGVMLYQMITGRRPFEACSSE-DLFRKL--
 |||.|||.. .|..                 |.. .|..||  .||||||.       ..||.|.| ||.| ..  |.||. |.   .    .|...  
-VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFN

--------------GNKVQFRGEDC-----------------WDPDCRDLCEGLLRKNPLERISFEEFFN--HKFL
              |.  ..  . .                 | |...|  .  |.|.| .| . ..  .  |.|.
YHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase ULK_a.AA Pkinase_Tyr 7-232 28 3.4e-36 123.22 Pfam 1-228 (270) Show / Hide 
Range on Protein: 7-232
Range on HMM: 1-228/270
Sequence Identity: 28% (70 aa)

YRLLHKIGVGSFATVWKAMHK----ITGEIVAIKVIVPRMDQLRQ--QLELIAQEQAIMKSI-AHPNVVKLLGMIS-EDEHDELSTRYLVMEFCEGGDLD
 ....|.| |.| .|.|.  |     |.  ||.|.. .     .|  . .... | .|||..  |||.|.|.| .. ..|.      |.|||....|||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPN---QIYIVMEYMPHGDLL

HYIHL----NKKLSAGVARTIMLQLSAALQELRRMNLIHRDLKPHNLLLKNKVAPGSDPEGEEIVVKLTDFGLARKLQPQGMA-QTMCGTYL---YMAPE
.| .     ...|.      . .| ..... | ..|.|||||   | |...           . ||| .|||||| ... .   ..  |. |    ||||
DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE-----------NNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPE

VISHNKYDAKADLWSVGVMLYQMIT-GRRP-FEACSSEDLFRKL
.|...|.  | | || || .. ..| |. | .. .| |......
CINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYI
Kinase ULK_a.AA MARK 7-143 36 2.5e-32 103.08 In-house 1-137 (262) Show / Hide 
Range on Protein: 7-143
Range on HMM: 1-137/262
Sequence Identity: 36% (52 aa)

YRLLHKIGVGSFATVWKAMHKITGEIVAIKVIVPRMDQLR-QQLELIAQEQAIMKSIAHPNVVKLLGMIS--EDEHDELSTRYLVMEFCEGGDLDHYIHL
|..|  || ||.|.| .| || ||. ||||..  . .  . |... .  | .|||.. |||..||. .|   . .|    . ||.|| ..||.| .||  
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYE-KFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQH----QIYLIMEYASGGELYDYIKA

N--KKLSAGVARTIMLQLSAALQELRRMNLIHRDLKPHNLLL
    .|.   ||.|  |.  |.. . ..| .|||.|| |.|.
HPNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILI
Kinase ULK_a.AA MARK 160-275 33 2.3e-28 89.97 In-house 145-262 (262) Show / Hide 
Range on Protein: 160-275
Range on HMM: 145-262/262
Sequence Identity: 33% (42 aa)

VKLTDFGLARKLQPQGMAQTMCGTYLYMAPEVISHNKYD-AKADLWSVGVMLYQMITGRRPFEACS--SEDLFRKLGNKVQFRGEDCW-----DPDCRDL
.|..|||.... .|  .  | |||. |||||...  .||  |.| || || || |..|. ||....   ..|..|  .      ....      ..||.|
IKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILR------GKYDIPCHVSKECRNL

CEGLLRKNPLERISFEEFFNHKFL
   ||  || ||.. ||  .|...
IQRLLTVNPEERPTIEEIMKHPWM
Kinase ULK_a.AA TyrKc 7-275 22 5.9e-26 93.46 SMART 1-280 (280) Show / Hide 
Range on Protein: 7-275
Range on HMM: 1-280/280
Sequence Identity: 22% (68 aa)

YRLLHKIGVGSFATVWKAMHKITGEIVAIKVIVPRMDQLRQQLELIAQEQAIMKSI--AHPNVVKLLGMISEDEHDEL---STRYLVMEFCEGGDLDHYI
 .|..|.| | | .|.|.. |   . ||.|.. .        .| . .|  ||...   |||.|.|.| .....          ..|||....|||..|.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN-FMYIEPLMIVMEYMPHGDLKDYL

HLNKK-LSAGVARTIMLQLSAALQELRRMNLIHRDLKPHNLLLKNKVAPGSDPEGEEIVVKLTDFGLARKLQPQ---------GMAQT--MC---GTYLY
. ... |.      ...| ..  . | ..|.|||||   | |....            .|| .||||.|..             ....   .     .  
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRW

MAPEVISHNKYDAKADLWSVGVMLYQMIT-GRRPFEA-----CSSEDLFRKLGNK-VQFRGED-------CWDPDCRDLCEGLLRKNPLERISFEEFFNH
||||.| ..|.  | | || ||... . | |  | .      .| ....... .     . ..       |  ..  .. .   . .| .| .|.|   |
MAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--H

KFL
...
ECF