WEE-S1_c

Species: S.moellendorffii
Alias: WEE-S1_c
External Links:
Annotation:

Classification

Group: Other
Family: WEE
Subfamily: WEE-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
WEE-S1_c.AA Protein None 125 None Fasta, JSON
WEE-S1_c.NA RNA None 378 None Fasta, JSON
WEE-S1_c.kin_dom Protein Kinase Domain None 88 None Fasta, JSON

Protein domain

Protein domains of WEE-S1_c.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase WEE-S1_c.AA WEE 27-111 27 1.8e-23 75.61 In-house 120-232 (297) Show / Hide
Range on Protein: 27-111
Range on HMM: 120-232/297
Sequence Identity: 27% (31 aa)

LLNALKHLHSH-GLTHLDVKSDKIYIRNC---------------------VYKIGDLGLASRID----GTISIEDGNLRYLLMELIND--DHSHLDKADM
....|.|.||. |. |.|.| . |.| .                      ..||||.|......     . ... |. ||.  |....  ...|| ||| 
ICQGLHHIHSNCGMVHMDIKPENIFISKKMNCNQIVNNDQQNNNDWWFNMMCKIGDFGHVTDMNSNNNNPHQEQEGDSRYMAPEILQGYYHYTHLYKADI

FSLGATFYKLTRY
||||.|.| |...
FSLGITIYELACN

Kinase WEE-S1_c.AA WEE 1-25 52 3.5e-10 30.43 In-house 64-88 (297) Show / Hide
Range on Protein: 1-25
Range on HMM: 64-88/297
Sequence Identity: 52% (13 aa)

HENVVRYFSSWFKNDFLYIQMELCE
|...|||.|.|  .| .|||||.|.
HPHIVRYYSAWEEDDHMYIQMEYCN

Kinase WEE-S1_c.AA Ciliate-B2 27-102 23 2e-08 15.83 In-house 113-197 (197) Show / Hide
Range on Protein: 27-102
Range on HMM: 113-197/197
Sequence Identity: 23% (20 aa)

LLNALKHLHSHGLTHLDVKSDKIYI-RNCVYKIGDLGLASRID--GTISIEDGNLRYLLMELINDD------HSHLDKADMFSLG
|...|  ...   .|||.| . | . .|  |.  | |  | .     |.|     .|   | ...|          ...| .|.|
LIDGLIQFRMYNILHLDIKPQNILFMQNGNYVYCDFGISSIKKDNQQIKIKGFTKKYASPEQMECDHNQTFVTNIDFQSDIYSMG

Kinase WEE-S1_c.AA Ciliate-E2 27-108 19 5.5e-07 20.0 In-house 154-289 (365) Show / Hide
Range on Protein: 27-108
Range on HMM: 154-289/365
Sequence Identity: 19% (27 aa)

LLN---------------ALKHLHSHG-LTHLDVKSDKIYIRNCVYKIGDLGLASRID----------------------GTISIE------------DG
.|.               ||..||| .   | | | . | .     || |.||. ..|                      .|...              |
ILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICG

NLRYLLMELINDDHS--------HLDKADMFSLGATFYKL
.. |.  | .|            .  |.|..||| ..| .
TPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEM

Kinase WEE-S1_c.AA CMGC 26-68 27 2e-06 16.02 In-house 188-255 (513) Show / Hide
Range on Protein: 26-68
Range on HMM: 188-255/513
Sequence Identity: 27% (19 aa)

MLLNALK--HLHSHG--LTHLDVKSDKIYIR-NCVY--------------------KIGDLGLASRID
..|..||  ..|||.    | | |   | |  || .                    ||.| |||  ..
QILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYH

Kinase WEE-S1_c.AA MOK 27-62 38 2e-06 15.9 In-house 109-144 (283) Show / Hide
Range on Protein: 27-62
Range on HMM: 109-144/283
Sequence Identity: 38% (14 aa)

LLNALKHLHSHGLTHLDVKSDKIYIRNCVYKIGDLG
|. .| |.|  |. | ||| . | |.. . |..| |
LCKSLDHMHRNGIFHRDVKPENILIKQDHLKLADFG

Kinase WEE-S1_c.AA CAMK 1-79 12 1.1e-05 13.51 In-house 97-277 (425) Show / Hide
Range on Protein: 1-79
Range on HMM: 97-277/425
Sequence Identity: 12% (23 aa)

HENVVRYFSSWFK-------------------NDFLYIQM---ELC---EM----------------------------------------LLNALKHLH
|.|... .  .                     ....|. |   |.|   |.                                        .. |....|
HPNIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCH

SHGLTHLDVKSDKIYIRNC------------------VYKIGDLGLASRIDG-------------------TISIEDGNLR
||.  |.| | . | . .                     || | |.| ..|.                   |...|.  ..
SHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMK

Kinase WEE-S1_c.AA ULK 1-64 23 1.2e-05 15.76 In-house 77-189 (329) Show / Hide
Range on Protein: 1-64
Range on HMM: 77-189/329
Sequence Identity: 23% (27 aa)

HENVVRYFS-SWFKND-FLYIQMELCEM----------------------------------LLNALKHLHSHGLTHLDVKSDKIYIRN-----------
|.|.|...  .. .|.  .|| ||.|.                                   .||..|.||.|.  | | | . | | |           
HPNIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVH

--CVYKIGDLGLA
   |.||.| |.|
PNGVLKIADFGFA

Kinase WEE-S1_c.AA Pkinase 27-125 28 1.9e-05 20.37 Pfam 117-228 (293) Show / Hide
Range on Protein: 27-125
Range on HMM: 117-228/293
Sequence Identity: 28% (33 aa)

LLNALKHLHSHGLTHLDVKSDKIYIR-NCVY----KIGDLGLA----SRIDGTISIEDGNLRYLLMELINDDHSHLDKADMFSLGATFYKLTRYSPPPVS
.| .|...||.|  | |.|.. | |  |..     ||.| |||       ..  .   | ..|.  |.|...  .  |.||.|.| ..| .    ||  .
ILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPG

R------RQYQAIC
.      .|.| ||
HCWHDNHDQMQMIC

Kinase WEE-S1_c.AA STE 1-25 34 2.6e-05 14.84 In-house 89-120 (359) Show / Hide
Range on Protein: 1-25
Range on HMM: 89-120/359
Sequence Identity: 34% (11 aa)

HENVVRYFSSWFKN-------DFLYIQMELCE
|.|.|.|. . ||.       | |.| ||...
HPNIVKYYGCYFKEGHNHKNDDELWICMEYMD

Kinase WEE-S1_c.AA PAKB 24-49 50 0.000107 13.23 In-house 101-126 (252) Show / Hide
Range on Protein: 24-49
Range on HMM: 101-126/252
Sequence Identity: 50% (13 aa)

CEMLLNALKHLHSHGLTHLDVKSDKI
|.  | ||  ||. |  | |.||| |
CRQVLQALAYLHAQGVIHRDIKSDSI

Kinase WEE-S1_c.AA STE20 1-25 41 0.000332 11.61 In-house 63-91 (288) Show / Hide
Range on Protein: 1-25
Range on HMM: 63-91/288
Sequence Identity: 41% (12 aa)

HENVVRYFSSWFKN----DFLYIQMELCE
|.|.|.|. | .|.    | |.| ||.|.
HPNIVKYYGSYLKDDTCDDELWIVMEYCG

Kinase WEE-S1_c.AA STE20 27-47 42 0.007433 6.62 In-house 126-146 (288) Show / Hide
Range on Protein: 27-47
Range on HMM: 126-146/288
Sequence Identity: 42% (9 aa)

LLNALKHLHSHGLTHLDVKSD
.| .|..|||..  | |.|.|
VLQGLDYLHSNHIIHRDIKAD

Kinase WEE-S1_c.AA Pkinase 1-26 38 0.023498 9.41 Pfam 59-84 (293) Show / Hide
Range on Protein: 1-26
Range on HMM: 59-84/293
Sequence Identity: 38% (10 aa)

HENVVRYFSSWFKNDFLYIQMELCEM
|.|.||.. ..  .| .|. ||.||.
HPNIVRLYDWFEDKDHIYMVMEYCEG

Kinase WEE-S1_c.AA Ciliate-E2 1-25 22 0.024982 3.78 In-house 91-117 (365) Show / Hide
Range on Protein: 1-25
Range on HMM: 91-117/365
Sequence Identity: 22% (6 aa)

HENVVRYFSSWF--KNDFLYIQMELCE
| |..... ..   ... .|. ||.|.
HPNIIKMYECFQEKDDNNIYLVMEYCQ

Kinase WEE-S1_c.AA PAKB 1-22 40 0.051617 3.4 In-house 55-76 (252) Show / Hide
Range on Protein: 1-22
Range on HMM: 55-76/252
Sequence Identity: 40% (9 aa)

HENVVRYFSSWFKNDFLYIQME
|.|.|. .||.  .| | . ||
HPNIVEMYSSYLVGDELWVVME

Kinase WEE-S1_c.AA STE 27-71 28 0.058037 2.87 In-house 160-201 (359) Show / Hide
Range on Protein: 27-71
Range on HMM: 160-201/359
Sequence Identity: 28% (13 aa)

LLNA-LKHLHSHGLTHLDVKSDKIYIRNCVYKIGDLGLASRIDGTI
.| . |..||||.  | |.|.. | .     |. | |...... ..
ILKGLLYYLHSHHIIHRDIKPANILL----VKLCDFGVCGQLTDSM