Gene STE-Un_b (S.moellendorffii)

STE-Un_b

Species: S.moellendorffii
Alias: STE-Un_b
External Links:
Annotation:

Classification

Group: STE
Family: STE-Unique

Sequence

Name Sequence Type Origin Length Description Download
STE-Un_b.AA Protein None 2102 None Fasta, JSON
STE-Un_b.NA RNA None 6309 None Fasta, JSON
STE-Un_b.kin_dom Protein Kinase Domain None 308 None Fasta, JSON

Protein domain

Protein domains of STE-Un_b.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc STE-Un_b.AA S_TKc 1735-2044 19 3.3e-16 60.86 SMART 1-231 (231) Show / Hide 
Range on Protein: 1735-2044
Range on HMM: 1-231/231
Sequence Identity: 19% (63 aa)

YRNRIRIAHGAFAQIYKATVNEEDGPRLVVLKTVELPKGPYEPCKFFDVYSEVQILEKFLGEPKISQLLDYGLESETFVLVLKHYKC---SLRAWRLNQG
|.    | .|||.. ||.. ..    |.| .| .             ....|.|||.|  . | | .|.|.  . . . .|. .      .|.    ..|
YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK-----------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRG

G--LHSHKSGKSFVDRLPLYLEVYAAVLDAVKVLEAHNVVHYDLKCDNVLLEPVDSVISEEEFWDPTWPPSEENSHPLPFRVCLADFGQSKASVFQGGEC
.  |.       |.        . . ...|.. .  |...| ||| .|.||                             .. ..||| ..         
RHGLR-------FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---------------------------HIKICDFGLARQL-------

TVRNRGTEYVKSPEMLKLLRTGGDASLDTCVGK-AVDVWGLGCLLYELLAAEYLLYDEDWMRFFIRVTTNSEELITNEKAEKVGNFGPVVEFIRFVLVRD
     || .  .||.|               || ..|.| .||.|||.|. . . .  . .. | ..                    .. .|||  |..|
-TTFCGTPWYMAPEVL-------------GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-----------------SPEAKDFIRKCLQKD

PCRRPTLDEVMI-------HLRQ
| .|||  |..        |   
PEKRPTA-EALQDEWDIKCHPWF
Kinase STE-Un_b.AA Ciliate-E2 1854-1977 17 1.1e-12 39.91 In-house 167-290 (365) Show / Hide 
Range on Protein: 1854-1977
Range on HMM: 167-290/365
Sequence Identity: 17% (27 aa)

AAVLDAVKVLEAHN-VVHYDLKCDNVLLEPVDSVISEEEFWDPTWPPSEENSHPLPFRVCLADFGQSKASVFQ---------GGECTVRN----------
| ...|.. |   | ..| |.| .|.|.                              ....||| ||    .          ....  .          
ACIILALEYLHSKNNIIHRDIKPENILF------------------------------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYM

------------RGTEYVKSPEMLKLLRTGGDASLDTCVGKAVDVWGLGCLLYELL
             || . ..||.|.    ... .. .  ....|.| ||..|||.|
DQIIQQNMFNTICGTPGYMAPEILNGKKYDNQ-QKQKGYDYKCDIWSLGVILYEML
Kinase STE-Un_b.AA AGC 1941-1978 37 5.6e-11 23.1 In-house 275-300 (395) Show / Hide 
Range on Protein: 1941-1978
Range on HMM: 275-300/395
Sequence Identity: 37% (15 aa)

SPEMLKLLRTGGDASLDTCVGKAVDVWG--LGCLLYELLA
.||.|               |||.| |.  ||||.||.|.
APEIL--------------YGKACDWWSFGLGCLMYEMLT
Kinase STE-Un_b.AA Pkinase 1866-2042 18 8.9e-11 39.18 Pfam 127-293 (293) Show / Hide 
Range on Protein: 1866-2042
Range on HMM: 127-293/293
Sequence Identity: 18% (37 aa)

HNVVHYDLKCDNVLLEPVDSVISEEEFWDPTWPPSEENSHPLPFRVCLADFGQSK-ASVFQGGECTVRNRGTEYVKSPEMLKLLRTGGDASLDTCVGKAV
....| ||| .|.|.   . . .                     .|...||| .| ..    .. .    || .  .|| ..          ..  |..|
MGIIHRDLKPENILIDNNGHIDA---------------------CVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIR---------GGQYYGPKV

DVWGLGCLLYELLAAEYLLYDE------DWMRFFIRVTT----NSEELITNEKAEKVGNF-----------GPVVEFIRFVLVRDPCRRPTLDEVMIH--
|.|..||.|||.|  . . ...      | |  . |.       ...   ..  ..  ..            .  .||.  | .|| .||| .... |  
DMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFF-FRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPW

L
.
F
Kinase STE-Un_b.AA Ciliate-E2-Unclassified 1867-1977 18 3.2e-09 28.17 In-house 164-264 (352) Show / Hide 
Range on Protein: 1867-1977
Range on HMM: 164-264/352
Sequence Identity: 18% (24 aa)

NVVHYDLKCDNVLLEPVDSVISEEEFWDPTWPPSEENSHPLPFRVCLADFGQSKASVFQGGECTVRN---------------RGTEYVK----SPEMLKL
|..|.|.|..|.|.    .                       ......||| || .  . ..   ..                || . .    .||.|. 
NIIHRDIKPENILFDNNGK----------------------NYYIKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQG

LRTGGDASLDTCVGKAVDVWGLGCLLYELL
   .. ..      ...|.|.||..|||.|
QNYDHSKA------YKCDIWSLGVILYEML
Kinase STE-Un_b.AA CAMK 1856-2041 18 8.2e-09 23.78 In-house 188-422 (425) Show / Hide 
Range on Protein: 1856-2041
Range on HMM: 188-422/425
Sequence Identity: 18% (49 aa)

VLDAVKVLEAHNVVHYDLKCDNVLLEPVDS-----VISEEEFWDPTWPPSEENSHPLPFR-VCLADFGQSKA----------SVFQGGECTVRN------
...||. .  ||.|| |||..|.||   ..     . . | | |            .    . ..||| ..           | ..|||   .|      
ICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVE-HDEIF-D------------WNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HNQWTTPT

--------RGTEYVKS-PEMLKL--------LRTGGDASLDTCVGKAVDVWGLGCLLYELLAAEYLLYDE-------------DWMRFFIRVTTNSEE-L
         || .  . ||.|.           |   .   . .|...|.| .|..|| .|  ..  |..             .  . | ....   .  
EGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNA-T---DEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFP

------------------ITNEKAEKVGNFGP------VVEFIRFVLVRDPCRRPTLDEVMIH
                  |..|       | .      .  .||  |..|| .|.|..... |
PPYFSPISCNYGPEWWDDISDE-------F-HHFVSQECKDLIRKMLQVDPEKRMTIEQCLNH
Kinase STE-Un_b.AA TyrKc 1735-2042 14 2.9e-07 -105.22 SMART 1-280 (280) Show / Hide 
Range on Protein: 1735-2042
Range on HMM: 1-280/280
Sequence Identity: 14% (49 aa)

YRNRIRIAHGAFAQIYKATVNEEDGPRLVVLKTVELPKGPYEPCKFFDVYSEVQILEKF-LGEPKISQLLDYGLES-------ETFVLVLKHYKC-SLRA
 .    . .||| ..||.| .     . |  |..   .         | ..| .|. |.    | | .|. . ...       |   .|. . .  .|. 
ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

WRLNQGGLHSHKSGKSFVDRLPLYLEVYAAVLDAVKVLEAHNVVHYDLKCDNVLLEPVDSVISEEEFWDPTWPPSEENSHPLPFRVCLADFGQSKASVFQ
   . ..             ..  |.    . .    |. .|..| || . |.|.                             .|  .||| |..    
YLRKHRPK----------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-------------------------TVKISDFGLSRD----

GGEC--------TVRNRGTEYVK--------SPEMLKLLRTGGDASLDTCVGKAVDVWGLGCLLYELLAAEYLLYDEDWMRFFIRVTTNSEELITNEKAE
...         . | ....  |        .|| .           . .   . |||  | ...|..      | ..  . ..  .   | . . .  .
IYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI----------NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMP

KVGN---------FGPVVEFIRFVLVRDPCRRPTLDEVMIHL
.  |            . . ..    .||  |||  |.   .
QPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase STE-Un_b.AA Akt 1961-1977 61 2e-06 16.61 In-house 180-197 (264) Show / Hide 
Range on Protein: 1961-1977
Range on HMM: 180-197/264
Sequence Identity: 61% (11 aa)

GKAVDVWG-LGCLLYELL
.|||| || |||..||..
TKAVDWWGSLGCVMYEMM
Kinase STE-Un_b.AA Delta 1854-1977 21 4e-06 18.08 In-house 107-194 (259) Show / Hide 
Range on Protein: 1854-1977
Range on HMM: 107-194/259
Sequence Identity: 21% (27 aa)

AAVLDAVKVLEAHNVVHYDLKCDNVLLEPVDSVISEEEFWDPTWPPSEENSHPLPFRVCLADFGQSKASVFQGGECTVRNRGTEYVKSPEMLKLLRTGGD
. .. ... |  ....  ||| |||||.                             . .|||| .|  ...  . .    ||    .||..|  .    
CEIICGLQFLHKKGIIYRDLKLDNVLLDCD-------------------------GHIKIADFGMCKENMYGE-KKASTFCGTPDYIAPEIIKGQK----

ASLDTCVGKAVDVWGLGCLLYELL
        ..|| |  | |.||.|
------YNHSVDWWSFGVLMYEML
Kinase STE-Un_b.AA STE 1855-1977 18 4e-06 17.91 In-house 159-262 (359) Show / Hide 
Range on Protein: 1855-1977
Range on HMM: 159-262/359
Sequence Identity: 18% (26 aa)

AVLDA-VKVLEAHNVVHYDLKCDNVLLEPVDSVISEEEFWDPTWPPSEENSHPLPFRVCLADFGQSKASVF---------------QGGECTVRNRGTEY
..| .  . |. |...| |.|..|.||                              | |.||| ..  .                 ... .    ||  
QILKGLLYYLHSHHIIHRDIKPANILL------------------------------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-

VKSPEMLKLLRTGGDASLDTCVGKAVDVWGLGCLLYELL
  .||...  ..|     |   .  .|.| |||.. |..
WMAPEVIQQNGQG-R---DKGYDTKCDIWSLGCTIIEMA
Kinase STE-Un_b.AA Ciliate-B3 1848-1881 32 7e-06 18.0 In-house 1-34 (69) Show / Hide 
Range on Protein: 1848-1881
Range on HMM: 1-34/69
Sequence Identity: 32% (11 aa)

LYLEVYAAVLDAVKVLEAHNVVHYDLKCDNVLLE
. |. .  |.. .|.|   |. | |.| ||.|..
FALKHFHQVVEKIKILHEKNICHCDIKVDNILVN
Kinase STE-Un_b.AA CMGC 1961-1982 20 0.000104 10.38 In-house 313-342 (513) Show / Hide 
Range on Protein: 1961-1982
Range on HMM: 313-342/513
Sequence Identity: 20% (6 aa)

GKAVDVWGLGCLLYELLAA--------EYL
....|.|..|| ..|..          ..|
TTPIDMWSVGCIFAEMYTGYQSLIFRGKPL
Kinase STE-Un_b.AA CAMK 1740-1805 14 0.000794 7.42 In-house 1-106 (425) Show / Hide 
Range on Protein: 1740-1805
Range on HMM: 1-106/425
Sequence Identity: 14% (15 aa)

RIAHGAFAQIYKATVNEEDG----------PRLVVLKTVELPKGPY------------------------EPCKFFDVYSEVQILEK------FLGEPKI
 . .|.|.. ....  .  |          .. |  | ..  | .                         .|..   |..|..|. |      .|  | |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

SQLLDY
 .|...
IKLYEV
Kinase STE-Un_b.AA NAK-Unclassified 2021-2044 37 0.001041 8.51 In-house 382-405 (405) Show / Hide 
Range on Protein: 2021-2044
Range on HMM: 382-405/405
Sequence Identity: 37% (9 aa)

IRFVLVRDPCRRPTLDEVMIHLRQ
|...|. ||  ||.. .|  |. |
IKIMLNEDPIQRPNIYQVLNHICQ
Kinase STE-Un_b.AA CMGC 1735-1805 14 0.001276 6.74 In-house 1-106 (513) Show / Hide 
Range on Protein: 1735-1805
Range on HMM: 1-106/513
Sequence Identity: 14% (16 aa)

YRNRIRIAHGAFAQIYKATVNEEDGP------------RLVVLKTVELPKGPYEPCK--------FFDVYSEVQILEKF----------------LGEPK
| .  .| .|.... ||.. .. ...            ..| .| . .|.   | .|         .  . |..||...                  .. 
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

ISQLLDY
| .|.|.
IVKLYDI
Kinase STE-Un_b.AA CMGC 1856-1917 18 0.001526 6.48 In-house 189-249 (513) Show / Hide 
Range on Protein: 1856-1917
Range on HMM: 189-249/513
Sequence Identity: 18% (14 aa)

VLDAVK--VLEAHN--VVHYDLKCDNVLLEPVDSVISEEEFWDPTWPPSEENSHPL----------PFRVCLADFG
.| ..|   .  |.  ..| |||  |.|. .   .|...                .           .|. ..|||
ILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRM-M--------------WKSEDWNPCQKNGRLKICDFG
Kinase STE-Un_b.AA NAK-Unclassified 1964-1977 50 0.002451 7.19 In-house 325-338 (405) Show / Hide 
Range on Protein: 1964-1977
Range on HMM: 325-338/405
Sequence Identity: 50% (7 aa)

VDVWGLGCLLYELL
.|.| |||.|| ..
IDIWALGCFLYKMC
Kinase STE-Un_b.AA STE 1735-1752 38 0.148516 1.41 In-house 1-18 (359) Show / Hide 
Range on Protein: 1735-1752
Range on HMM: 1-18/359
Sequence Identity: 38% (7 aa)

YRNRIRIAHGAFAQIYKA
...  .| .||| . |||
WEGIEKIGKGAFGTVYKA