Gene STE11-p2_a (S.moellendorffii)

STE11-p2_a

Species: S.moellendorffii
Alias: STE11-p2_a
External Links:
Annotation:

Classification

Group: STE
Family: STE11
Subfamily: MEKK2-plant2

Sequence

Name Sequence Type Origin Length Description Download
STE11-p2_a.AA Protein None 288 None Fasta, JSON
STE11-p2_a.NA RNA None 867 None Fasta, JSON
STE11-p2_a.kin_dom Protein Kinase Domain None 267 None Fasta, JSON

Protein domain

Protein domains of STE11-p2_a.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase STE11-p2_a.AA STE11 102-267 46 1.2e-87 297.47 In-house 100-296 (303) Show / Hide 
Range on Protein: 102-267
Range on HMM: 100-296/303
Sequence Identity: 46% (92 aa)

LNSMLE-RFGR--FSEPLVRVYTRQLLLGLQYLHENRIVHRDIKGGNVLVDAIGV-VKLADFGASKAFH-DPTVTNE-------CKSIRGSVF-------
| |||. ..|.  |.|...|.||.|.| ||||||...|.|||||| |.|.|. |. .||||||..| .  . | | .       |||..|...       
LSSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGTP

-WMAPEVIKGDG---YGRRADIWSVGCTVIEMLTAMHPWPDIDN-TWSAIFHIAKA-SSGPPIPEHGS------GCVKDFLQQCFQMDPRLRPTATQ
 ||||||||. |   |||.|||||.|||||||.|. .||...|. .. |.|.|...  . |||||| |         .|||..||. ||  |||| |
MWMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQ
Kinase STE11-p2_a.AA STE11-Unclassified 102-267 41 1.4e-86 293.97 In-house 94-301 (308) Show / Hide 
Range on Protein: 102-267
Range on HMM: 94-301/308
Sequence Identity: 41% (86 aa)

LNSMLERFGRFSEPLVRVYTRQLLLGLQYLHENRIVHRDIKGGNVLVDAIGVVKLADFGASK---------------------AFHDPTVT--NECKSIR
. |||...|.|.|.. ..||.|.| ||.|||.. |.||||||.|.|.|. |..||.|||..|                       . ..    | |||..
IWSMLNKYGCFDEMVIKKYTKQILEGLAYLHSHGIIHRDIKGANILIDFDGICKLTDFGCAKQIEFDRTRTVRMNKIQNFDHYKICQHINSQQNHCKSMQ

GSVF---WMAPEVIK---GDGYGRRADIWSVGCTVIEMLTAMHPWPDIDN--TWSAIFHIAKASSGPPIPEHGS-----------GCVKDFLQQCFQMDP
|...   ||||||||    .|..|..||||.||||||| |. |||....|     ||..|... . |.|||| |              ||||..||| ||
GTPYQPFWMAPEVIKNSTQTGHCRKSDIWSLGCTVIEMATGKHPWSNCQNDNFMWAIMKIVMSNQIPQIPEHLSPVCDFISCWISQECKDFLRKCFQIDP

RLRPTATQ
  ||||.|
KKRPTANQ
Kinase STE11-p2_a.AA STE 7-267 27 2.5e-80 273.17 In-house 12-350 (359) Show / Hide 
Range on Protein: 7-267
Range on HMM: 12-350/359
Sequence Identity: 27% (95 aa)

FSQVFSGLNQ------STGEL---------MAVKQLKIDPGEGQEKS------------FYLAALEREINLYRKLR--HKHIVGYINMEQDE---QSG--
| .|. ..|       .|||.         ||.||..... .  . .              .  ...||.. .|..  |..|| |. .. .|   ..   
FGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYFKEGHNHKNDD

SLYIFLEYVSGGSIQRQAAYFNFSYHLLLLNSMLERFGRFSEPLVRVYTRQLLLG-LQYLHENRIVHRDIKGGNVLVDAIGVVKLADFGASKAFHD----
.|.|..||..|||. ..    ...    | ..  . ..||.|.......||.| | |.|||...|.|||||..|.|.     |||.||| .. . |    
ELWICMEYMDGGSL-DDIIKHKYGCGKPLNHNRQH-QHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMAN

----------PTVTNECKSIRGSVFWMAPEVIKG------DGYGRRADIWSVGCTVIEMLTAMHPWPDIDNT---WSAIFHIAKAS----------SGPP
           |   ..... |.  |||||||..      .||....||||.|||.|||.|  .|| |  ..   . ..| .....            ||
IQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPP

IPEHGS-------------------GCVKDFLQQCFQMDPRLRPTATQ
.|.| |                    . |||...|.|.||. ||||.|
LPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ
Kinase STE11-p2_a.AA MEKK2 1-274 41 1.8e-69 237.15 In-house 6-262 (262) Show / Hide 
Range on Protein: 1-274
Range on HMM: 6-262/262
Sequence Identity: 41% (115 aa)

LLRSSEFSQVFSGLNQSTGELMAVKQLKIDPGEGQEKSFYLAALEREINLYRKLRHKHIVGYINMEQDEQSGSLYIFLEYVSGGSIQRQAAYFNFSYHLL
||    | .|.      ||  .|||| ..|| .  | .    ||| ||.| . |.|. || |    .|.|   | ||.||..|||.. |           
LLGQGAFGRVYVCYDVDTGRELAVKQVQFDP-DNPETRKEVQALECEIQLLKNLQHERIVQYYGCLRDNQEKTLSIFMEYMPGGSVKDQ-----------

LLNSMLERFGRFSEPLVRVYTRQLLLGLQYLHENRIVHRDIKGGNVLVDAIGVVKLADFGASKAFHDPTVTNE-CKSIRGSVFWMAPEVIKGDGYGRRAD
     |  .|   |   | ||||.| |..|||.. |||||||| |.| |. | |||.||||||      .     ||. |  .||.|||| |.||||.||
-----LKAYGALTETVTRKYTRQILEGMHYLHDHMIVHRDIKGANILRDSSGNVKLGDFGASKRLQTICMHITGMKSVTGTPYWMSPEVINGEGYGRKAD

IWSVGCTVIEMLTAMHPWPDIDNTWSAIFHIAKASSGPPIPEHGSGCVKDFLQQCFQMDPRLRPTATQVFYPCLV
.||.||||.||||   || . .    ||| ||     | .|.| |   .|||..||.     || |  .     |
VWSIGCTVVEMLTEKPPWAEYE-AMAAIFKIATQPTNPQLPQHVSQHARDFLKRCFVEIKQDRPSAEELLRHHFV
Kinase STE11-p2_a.AA S_TKc 7-276 27 2e-69 237.85 SMART 12-231 (231) Show / Hide 
Range on Protein: 7-276
Range on HMM: 12-231/231
Sequence Identity: 27% (78 aa)

FSQVFSGLNQSTGELMAVKQLKIDPGEGQEKSFYLAALEREINLYRKLRHKHIVGYINMEQDEQSGSLYIFLEYVSG--GSIQRQAAYFNFSYHLLLLNS
|..|. . . .||...|.|..|               ..|||.. .| .|..|| .. . ||   ..||...||..|  |.                | .
FGKVYKCRHKKTGRIVAIKIIK-------------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGD----------------LFD

MLERFGR------FSEPLVRVYTRQLLLGLQYLHENRIVHRDIKGGNVLVDAIGVVKLADFGASKAFHDPTVTNECKSIRGSVFWMAPEVIKGDGYGR-R
.... ||      |.|  .| |..|....|.|.|...|.|||.|  |.|.|   ..|..||| .. .         ... |. ..|||||.   |||. .
YIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCK

ADIWSVGCTVIEMLTAMHPWPDIDNTWSAIFHIAKASSGPPIPEHGSGCVKDFLQQCFQMDPRLRPTATQVFYPC-----LVFF
.|.||.||...|||.   |.|    .  ..|.. .           |  .|||...|.|.||. |||| ...  .       .|
CDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase STE11-p2_a.AA Pkinase 7-269 28 3.1e-64 224.52 Pfam 12-288 (293) Show / Hide 
Range on Protein: 7-269
Range on HMM: 12-288/293
Sequence Identity: 28% (87 aa)

FSQVFSGLNQSTGELMAVKQLKIDPGEGQEKSFYLAALEREINLYRKLRHKHIVGYINMEQDEQSGSLYIFLEYVSGG----SIQ----RQAAYFNFSYH
|..|. . ...||.. |||..| . .|  .|  ... | .|| . ..|.|..|| .. . .|  ....|. .||. ||    .      .          
FGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST----------

LLLLNSMLERFGRF--SEPLVRVYTRQLLLGLQYLHENRIVHRDIKGGNVLVDAIGVV----KLADFGASKAFHDPTVTNECKSIRGSVFWMAPEVIK-G
        .| |.|  ||  .. | .|.| ||.|.|...|.|||.|  |.|.|  |..    |..||| .| |   .  |..... |. ..||||||. |
--------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNSMTTFCGTPWYMAPEVIRGG

DGYGRRADIWSVGCTVIEMLTAMHPWPDI---DNTWSAIFHIAKASSGPPIPEHGSGC----------------------VKDFLQQCFQMDPRLRPTAT
 .||...|.||.||...|||.   |.|.    ||  . .. |..  ..|.  .    |                       |||.  |...||  ||||.
QYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAE

QVF
|..
QIL
Kinase STE11-p2_a.AA MEKK15 1-274 37 7.4e-61 208.5 In-house 6-264 (264) Show / Hide 
Range on Protein: 1-274
Range on HMM: 6-264/264
Sequence Identity: 37% (105 aa)

LLRSSEFSQVFSGLNQSTGELMAVKQLKIDPGEGQEKSFYLAALEREINLYRKLRHKHIVGYINMEQDEQSGSLYIFLEYVSGGSIQRQAAYFNFSYHLL
.|    .  |. ||  .|| |.|||| ..|  . ..       |  |..| . |.|| ||.|. .  ..    . ||...| ||||              
ILGKGAYGTVYCGL-TNTGQLIAVKQVELDEIDKEKAKQQYRKLQEEVDLLKTLKHKNIVAYLGVCLEDN--VVNIFMQFVPGGSIS-------------

LLNSMLERFGRFSEPLVRVYTRQLLLGLQYLHENRIVHRDIKGGNVLVDAIGVVKLADFGASK--AFH--DPTVTNECKSIRGSVFWMAPEVIKGDGYGR
   |.. |||   |     ||.|.| | |||||| .||||||| ||.. . |..|| |||  |  ..   . | ..  ||.||  .|||||||.  ||||
---SIINRFGPLDEMVFCKYTKQILQGVQYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCAKRLCWQGINRTHSDMLKSMRGTPYWMAPEVIMETGYGR

RADIWSVGCTVIEMLTAMHPWPDIDNTWSAIFHIAKA-SSGPPIPEHGSGCVKDFLQQCFQMDPRLRPTATQVFYPCLV
..||||.|||| || |   || |.|    |.| |       |..|.. |   ..| . |   |   |||| |.     .
KSDIWSIGCTVFEMATRKPPWADMDR-MAAMFYIGAHRDPMPQLPVKFSEDARMFVRMCLTRDQHERPTASQLLKHPFI
Kinase STE11-p2_a.AA ASK 1-274 35 2.7e-55 182.28 In-house 1-254 (254) Show / Hide 
Range on Protein: 1-274
Range on HMM: 1-254/254
Sequence Identity: 35% (99 aa)

LLRSSEFSQVFSGLNQSTGELMAVKQLKIDPGEGQEKSFYLAALEREINLYRKLRHKHIVGYINMEQDEQSGSLYIFLEYVSGGSIQRQAAYFNFSYHLL
 |    .  |. | ...|   .|.| ..    .      |   |  ||.|...|||. || |.    . . | . ||.| | |||.              
VLGKGTYGIVYAGRDMHTQVRIAIKEIPERDSR------YVQPLHEEIALHKQLRHRNIVQYLGC--CSENGYFKIFMEQVPGGSLSA------------

LLNSMLERFGRFS--EPLVRVYTRQLLLGLQYLHENRIVHRDIKGGNVLVDAI-GVVKLADFGASKAFHDPTVTNECKSIRGSVFWMAPEVI-KGD-GYG
|| |   ..| .   |  .. ||.|.| ||.|||||.|||||||| ||||    ||||..||| .|      ..   .. .| . .|||||| .|  |||
LLRS---KWGPMKDNENTMNFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTCKRLA--GINPCTETFTGTLQYMAPEVIDQGQRGYG

RRADIWSVGCTVIEMLTAMHPWPDIDNTWSAIFHIAKASSGPPIPEHGSGCVKDFLQQCFQMDPRLRPTATQVFYPCLV
. |||||.|||..|| |.  |. ....   |.|..      |.|||  |   |.|. .||. ||. |..| ..     .
KPADIWSFGCTMVEMATGKPPFHELGEPQAAMFKVGMYKKHPEIPEELSAECKNFILRCFEPDPCKRASAQDLLQDPFL
Kinase STE11-p2_a.AA TKL 2-268 19 1.9e-45 157.3 In-house 1-360 (364) Show / Hide 
Range on Protein: 2-268
Range on HMM: 1-360/364
Sequence Identity: 19% (75 aa)

LRSSEFSQVFSG-LNQST-------GELMAVKQLKIDPG---------------------EGQEKSFYLAALEREINLYRKLRHKHIVGYINMEQDEQSG
. |  |..|. | ... .       |. .|||..|..                       . .| |..   .|.||.. ..||| .|| ..   .....|
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

S-----------LYIFLEYVSGGSIQRQAAYFNFSYHLLLLNSMLERFGRFSEPLVRVYTRQLLLGLQYLHENR--------IVHRDIKGGNVLVDAIGV
            |.|  ||..|||   .                         ..     ..  .|..||| ..        |.|||.|  |.|||  . 
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWT

--------------VKLADFGASKAFHDPTVTNECKS-----------------IRGSVFWMAPEVIKGD----------------GYGRRADIWSVGCT
              .|..||| |. ..  .  |  ..                 ..|.  ||||||..|.                 |  ..|..| |  
NVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIV

VIEMLTAMHPWPDID-NTWSAI-------FHIAKASSGPPIP---------EHGSGC---VKDFLQQCFQMDPRLRPTATQV
  |.||  .|. |.. ... .          ... .  ||||          . . |   .|. .|.| ..||. ||.....
LWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEI
Kinase STE11-p2_a.AA Dicty2 102-267 40 1.2e-44 153.38 In-house 90-257 (264) Show / Hide 
Range on Protein: 102-267
Range on HMM: 90-257/264
Sequence Identity: 40% (70 aa)

LNSMLERFGRFSEPLVRVYTRQLLLGLQYLHENRIVHRDIKGGNVLVDAIGV---VKLADFGASKAFHDPTVTNECKSIRGSVFWMAPEVIKGDG--YGR
|   ...|| |.|.|. .| .| | || |||.. ..|||||. | |.   |.   .||||||    .      .   .. |  .|||||||  .|     
LSKIIKKFGCFPESLCCIYIYQVLKGLVYLHRQGVIHRDIKAANILITKEGKSGVIKLADFGVATHID-YSDDDSRYTVVGTPYWMAPEVIQMSGNHCCT

RADIWSVGCTVIEMLTAMHPWPDIDNTWSAIFHIAKASSGPPIPEHGSGCVKDFLQQCFQMDPRLRPTATQ
  ||||.|||.||.||   |  |  |.  | | .      ||.|.  |   ||||.|||. || .|.|| |
ACDIWSLGCTIIELLTGNPPYWDL-NPMHAMFRMVQDDH-PPLPNDISPECKDFLMQCFCKDPNQRMTAKQ
Kinase STE11-p2_a.AA MEKK4 110-267 38 1.4e-43 147.37 In-house 93-264 (271) Show / Hide 
Range on Protein: 110-267
Range on HMM: 93-264/271
Sequence Identity: 38% (66 aa)

GRFSEPLVRVYTRQLLLGLQYLHENRIVHRDIKGGNVLVDAIGVVKLADFGASKAFHDPT--VTNECKSIRGSVFWMAPEVI---KGD-------GYGRR
|   | ..| || ||| . .|||.  |||||||. |.  |  .|.|| ||| |    . .  .  |  |  |.  .|||||.   ..|       |.|| 
GNMQEHMIRQYTKQLLRAVNYLHQHGIVHRDIKPANIFLDKCTVLKLGDFGCSVKLQNHSQTMPGEFQSTMGTAAYMAPEVYTYTEKDETTGSYSGHGRA

ADIWSVGCTVIEMLTAMHPWP---DIDNTWSAIFHIAKASSGPPIPEHGSGCVKDFLQQCFQMDPRLRPTATQ
|||||.||.|.|| |   ||    . |      .   .    |.||.  |  .|||.  |.. ||  |.|| .
ADIWSLGCVVVEMMTGKRPWHGQTQYDHNFQIMYKVGMGHY-PHIPDKMSPEGKDFFDHCLEHDPKDRWTANE
Kinase STE11-p2_a.AA STE20 110-267 39 2.3e-43 150.39 In-house 111-281 (288) Show / Hide 
Range on Protein: 110-267
Range on HMM: 111-281/288
Sequence Identity: 39% (68 aa)

G-RFSEPLVRVYTRQLLLGLQYLHENRIVHRDIKGGNVLVDAIGVVKLADFG-ASKAFH--DPTVTNECK--SIRGSVFWMAPEVIKG-----DGYGRRA
| ...|. . . .|..| ||.|||.|.|.|||||..|.|..  | ||||||| ...  .    . |. .|  .. |. .|||||||..      ||. ..
GHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGR-D-TMQFKRNTFVGTPYWMAPEVIQCMEGPDKGYDYKC

DIWSVGCTVIEMLTAMHPWPDIDNTWSAIFHIAKASSGPP---I--PEHGSGCVKDFLQQCFQMDPRLRPTATQ
||||.| | |||..   |  |.  . .|.|.|.| . .||      |.. | . .||. .| |.||  ||||.|
DIWSLGITAIEMAEGEPPYFDMHPM-RAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQ
Kinase STE11-p2_a.AA STE11 7-88 35 5.2e-27 94.83 In-house 12-102 (303) Show / Hide 
Range on Protein: 7-88
Range on HMM: 12-102/303
Sequence Identity: 35% (32 aa)

FSQVFSGLNQSTGELMAVKQLKIDPGE---GQEKSFYLA-----ALEREINLYRKLRHKHIVGYINMEQDE-QSGSLYIFLEYVSGGSIQR
|..|....| .||||||||| .|.. .   .. . .| .     |.. ||.|...|.||.|| |.  .... | ....||.||..|||. .
FGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSLSS
Kinase STE11-p2_a.AA STE11-Unclassified 9-88 35 5.6e-25 85.49 In-house 14-96 (308) Show / Hide 
Range on Protein: 9-88
Range on HMM: 14-96/308
Sequence Identity: 35% (30 aa)

QVFSGLNQSTGELMAVKQLKI-DPG----EGQEKSFYLAALEREINLYRKLRHKHIVGYINMEQDEQSGSLYIFLEYVSGGSIQR
||....| .|||.|||||..| |      . |..   . ... |......|.||.|| |.  | ... ....||.||..|||| .
QVYKCMNCNTGEFMAVKQIEIHDYNSQQEDMQKE--MIQSIQKEMKVLKQLNHKNIVQYYGCEIHKHEDCINIFMEYMPGGSIWS
Kinase STE11-p2_a.AA Pkinase_Tyr 127-273 28 9.9e-17 57.29 Pfam 123-270 (270) Show / Hide 
Range on Protein: 127-273
Range on HMM: 123-270/270
Sequence Identity: 28% (43 aa)

GLQYLHENRIVHRDIKGGNVLVDAIGVVKLADFGASKAF-HDPTV-TNECKSIRGSVFWMAPEVIKGDGYGRRADIWSVGCTVIEMLT-AMHP-WPDIDN
|..||......|||.   |.||.  .||| .||| ...  .| .  .   ..    ..|||||.|.   .    |.|| | .  |..|  . | .|..  
GMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGM-S

TWSAIFHIAKASSGPPIPEHGSGCVKDFLQQCFQMDPRLRPTATQVFYPCL
    . .|..     |.||. .  . | ..|| . ||  ||| ... . .|
NEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEI-HEQL
Kinase STE11-p2_a.AA TyrKc 6-273 21 3.7e-16 38.52 SMART 11-280 (280) Show / Hide 
Range on Protein: 6-273
Range on HMM: 11-280/280
Sequence Identity: 21% (66 aa)

EFSQVFSGLNQSTGELMAVKQLKIDPGEGQEKSFYLAALEREINLYRKL--RHKHIVGYINMEQDE-----QSGSLYIFLEYVSGGS----IQRQAAYFN
.| .|. |      .  ||| || |          .... ||... .||  .|..||  .    ..      .. |.| .||...|.    ...      
AFGEVYKGTWK---IQVAVKMLKEDA---------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK--

FSYHLLLLNSMLERFGRFSEPLVRVYTRQLLLGLQYLHENRIVHRDIKGGNVLVDAIGVVKLADFGASKAFHDP------TVTNECK---SIR--GSVFW
                 .. .    .  |   | .|||.....|||.   |.||.. ..|| .||| |.. .|       . .   |   . .    . |
-----------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRW

MAPEVIKGDGYGRRADIWSVGCTVIEMLT-AMHPWPD-ID--NTWSAIFHIAKASSGPPIPEH--------GSGCVKDFLQQCFQMDPRLRPTATQVFYP
||||.|.   .    |.|| | .  |..|  . |.|. |    ... ...  |.   .|.|..         .  . .  .|| . ||  ||| ... . 
MAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HE

CL
|.
CF
Kinase STE11-p2_a.AA Dicty2 7-85 36 7.6e-10 30.62 In-house 13-89 (264) Show / Hide 
Range on Protein: 7-85
Range on HMM: 13-89/264
Sequence Identity: 36% (29 aa)

FSQVFSGLNQSTGELMAVKQLKIDPGEGQEKSFYLAALEREINLYRKLRHKHIVGYINMEQDEQSGSLYIFLEYVSGGS
| .|. ||.  ||.  | || .|       .   .  .  ||.| .||.|  || ||  .. |    |||.|||. .||
FGTVYKGLHIETGDFVAIKQINIMKKKTKISEEQHQSIMQEIHLLKKLNHHNIVKYIEHIETEN--HLYIILEYIENGS
Kinase STE11-p2_a.AA MEKK4 7-84 26 1.1e-05 15.66 In-house 12-83 (271) Show / Hide 
Range on Protein: 7-84
Range on HMM: 12-83/271
Sequence Identity: 26% (22 aa)

FSQVFSGLNQSTGELMAVKQLKIDPGEGQEKSFYLAALER---EINLYRKLRHKHIVGY--INMEQDEQSGSLYIFLEYVSGG
|  |..  |  |.|.||.| . . ... .       |..    ||.  . ..|.  | |  .  .  |    .|||.|| | |
FGKVYTCMNMDTHEVMAMKEMRFQRNDHK-------AIKNIADEIKIFEGIKHPNLVRYYGVEVHREE----MYIFMEYCSQG
Kinase STE11-p2_a.AA STE20 9-87 22 6.3e-05 14.27 In-house 14-96 (288) Show / Hide 
Range on Protein: 9-87
Range on HMM: 14-96/288
Sequence Identity: 22% (20 aa)

QVFSGLNQSTGEL----MAVKQLKIDPG----EGQEKSFYLAALEREINLYRKLRHKHIVGYINMEQDEQS--GSLYIFLEYVSGGSIQ
.|. . . .|||.     |.|......     . .|       .. ||.  ....|..|| |..  . . .   .|.|  || .|||..
KVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWE------DIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLT
Kinase STE11-p2_a.AA Pkinase_Tyr 23-85 27 0.004014 11.2 Pfam 32-93 (270) Show / Hide 
Range on Protein: 23-85
Range on HMM: 32-93/270
Sequence Identity: 27% (19 aa)

AVKQLKIDPGEGQEKSFYLAALEREINLYRKL-RHKHIV---GYINMEQDEQSGS--LYIFLEYVSGGS
||| || .  . |    ..... ||... ..| .|..||   | .     .|...  .|| .||. .|.
AVKMLKEGAMHEQN---CREDFMREAKIMKQLGHHPNIVRLYGVCT----DQGEPNQIYIVMEYMPHGD