Gene NPK1-2 (S.moellendorffii)

NPK1-2

Species: S.moellendorffii
Alias: NPK1-2
External Links:
Annotation:

Classification

Group: STE
Family: STE11
Subfamily: NPK1

Sequence

Name Sequence Type Origin Length Description Download
NPK1-2.AA Protein None 1347 None Fasta, JSON
NPK1-2.NA RNA None 4044 None Fasta, JSON
NPK1-2.kin_dom Protein Kinase Domain None 263 None Fasta, JSON

Protein domain

Protein domains of NPK1-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase NPK1-2.AA Dicty2 20-282 60 3.2e-173 581.74 In-house 1-264 (264) Show / Hide 
Range on Protein: 20-282
Range on HMM: 1-264/264
Sequence Identity: 60% (165 aa)

YIIG-DEIGKGAYGRVYKGLDLENGDFVAIKQVS----LENIPPEDLASIMQEIDLLKNLNHKNIVKYRGSIKTKTHLYIILEYVENGSLASIVKPNKFG
| || . ||||| | |||||. | ||||||||..    . .|. | . ||||||.|||.||| ||||| ..|.|. ||||||||.|||||. |.|  |||
YQIGDEKIGKGAFGTVYKGLHIETGDFVAIKQINIMKKKTKISEEQHQSIMQEIHLLKKLNHHNIVKYIEHIETENHLYIILEYIENGSLSKIIK--KFG

AFPESLVAVYIAQALLTRYSQVLEGLAYLHEQGVIHRDIKGANILTTKEGF---VKLADFGVATKLT-EADVNTHSVVGTPYWMAPEVVEMSG--VSASS
 |||||. .||.        |||.||.|||.|||||||||.||||.||||    .|||||||||..   .|    .|||||||||||| .|||   . ..
CFPESLCCIYIY--------QVLKGLVYLHRQGVIHRDIKAANILITKEGKSGVIKLADFGVATHIDYSDDDSRYTVVGTPYWMAPEVIQMSGNHCCTAC

DIWSVGCTVIELLTCVPPYYDLQPMPALFRIVQDERPPIPEHLSPGLTDFLHQCFQKDAKLRPDAKTLLKHSWI
||||.|||.|||||  |||.||.||.|.||.||| .||.|.  || . ||| |||.||  .|..|| ||.| ||
DIWSLGCTIIELLTGNPPYWDLNPMHAMFRMVQDDHPPLPNDISPECKDFLMQCFCKDPNQRMTAKQLLHHPWI
Kinase NPK1-2.AA STE11 20-282 39 1.3e-113 383.69 In-house 1-303 (303) Show / Hide 
Range on Protein: 20-282
Range on HMM: 1-303/303
Sequence Identity: 39% (122 aa)

YIIGDEIGKGAYGRVYKGLDLENGDFVAIKQVSLENIPP------EDLAS------IMQEIDLLKNLNHKNIVKYRGSIK---TKTHLYIILEYVENGSL
.  |. |||||.|.|||.... .| ..|.||. ..|. .      . . |      |..|| |.|.|||||||.| |.      . |..|..||...|||
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSL

ASIVKPNKFGA--FPESLVAVYIAQALLTRYSQVLEGLAYLHEQGVIHRDIKGANILTTKEGF-VKLADFGVATKLT-EADVNTH---------SVVGTP
.|. .  |.|.  |.|... .|. |        .||||.|||..|.|||||||||||  ..|  .|||||| |..|  ..  ...         |. |||
SSMLR-HKWGPMKFDEMVIRKYTKQ--------ILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTP

Y--------WMAPEVVEMSG---VSASSDIWSVGCTVIELLTCVPPYYDLQ--PMPALFRIV-Q-DERPPIPEHLS------PGLTDFLHQCFQKDAKLR
|        ||||||.  .|    ....||||.|||||| .|  ||.....  .| |.|.|. . .  ||||||.|      . . ||| .||..| | |
YNSMMGTPMWMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKR

PDAKTLLKHSWI
| |  ||.|..|
PTANQLLQHPFI
Kinase NPK1-2.AA STE 20-282 31 1.1e-109 370.66 In-house 1-359 (359) Show / Hide 
Range on Protein: 20-282
Range on HMM: 1-359/359
Sequence Identity: 31% (119 aa)

YIIGDEIGKGAYGRVYKGLDLE---------------NGDFVAIKQVSLENIPP---------------EDLASIMQEIDLLKNLN--HKNIVKYRGSIK
. . ..|||||.| |||... .               .|...||||..|||  .               |.. .|..||...|..|  |.||||| |.  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

TK-------THLYIILEYVENGSLASIVK-------PNK-----FGAFPESLVAVYIAQALLTRYSQVLEG-LAYLHEQGVIHRDIKGANILTTKEGFVK
 .       ..|.|..||...||| .|.|       |..     .. ||||..|... |        .|.| |.|||....||||||.||||      ||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQ--------ILKGLLYYLHSHHIIHRDIKPANILL-----VK

LADFGVATKLTE---------------ADV-NTHSVVGTPYWMAPEVVEM------SGVSASSDIWSVGCTVIELLTCVPPYYDLQPMPALFRIVQD---
|.||||...||.                 . .. ..|||| ||||||..       .| ....||||.|||.||..|  ||. |..|| |.|.| .    
LCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHM

------------ERPPIPE-------------------HLSPGLTDFLHQCFQKDAKLRPDAKTLLK--HSWI
            . ||.|.                   ..|| . ||. .|.||| . ||.|. |||  |..|
QQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase NPK1-2.AA STE11-Unclassified 20-282 37 1.2e-103 350.66 In-house 1-308 (308) Show / Hide 
Range on Protein: 20-282
Range on HMM: 1-308/308
Sequence Identity: 37% (120 aa)

YIIGDEIGKGAYGRVYKGLDLENGDFVAIKQVSLENIP--PEDLASI-----MQEIDLLKNLNHKNIVKYRGSI--KTKTHLYIILEYVENGSLASIVKP
.  |. ||||..|.|||......| |.|.||.  ...    ||. ..      .|. .||.|||||||.| |    | .....|..||...||..|    
WQKGEFIGKGSFGQVYKCMNCNTGEFMAVKQIEIHDYNSQQEDMQKEMIQSIQKEMKVLKQLNHKNIVQYYGCEIHKHEDCINIFMEYMPGGSIWSML--

NKFGAFPESLVAVYIAQALLTRYSQVLEGLAYLHEQGVIHRDIKGANILTTKEGFVKLADFGVAT---------------------KLTEADVN----TH
||.|.| |.. ..|          |.||||||||..|.|||||||||||. ..| .||.||| |                      |....  .      
NKYGCFDEMVIKKYTK--------QILEGLAYLHSHGIIHRDIKGANILIDFDGICKLTDFGCAKQIEFDRTRTVRMNKIQNFDHYKICQHINSQQNHCK

SVVGTPY---WMAPEVVE---MSGVSASSDIWSVGCTVIELLTCVPPYYDLQP--MPALFR-IV-QDERPPIPEHLS-----------PGLTDFLHQCFQ
|  ||||   ||||||..     | ...|||||.||||||  |  .|....|.   ..... ||  .. |.||||||           . . ||| .|||
SMQGTPYQPFWMAPEVIKNSTQTGHCRKSDIWSLGCTVIEMATGKHPWSNCQNDNFMWAIMKIVMSNQIPQIPEHLSPVCDFISCWISQECKDFLRKCFQ

KDAKLRPDAKTLLKHSWI
 | | ||.|  ||.|..|
IDPKKRPTANQLLQHPFI
Kinase NPK1-2.AA STE20 20-282 39 2.4e-100 339.66 In-house 1-288 (288) Show / Hide 
Range on Protein: 20-282
Range on HMM: 1-288/288
Sequence Identity: 39% (118 aa)

YIIGDEIGKGAYGRVYKGLDLENGDF----VAIKQVSLENIPP--EDLASIMQEIDLLKNLNHKNIVKYRGSIKTK----THLYIILEYVENGSLASIVK
| . ..||.|.|| |||. . ..|.     ||||...||.  .  ... .|..||. .|...|.||||| ||   .    ..|.|. || . |||  |.|
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

-------PNKFG-AFPESLVAVYIAQALLTRYSQVLEGLAYLHEQGVIHRDIKGANILTTKEGFVKLADFGVATKLTE----ADV-NTHSVVGTPYWMAP
       ..| |  . |. .| || .       .||.||.|||....||||||..||| |..| ||||||||. .||.    ..     ..|||||||||
HCMKCGKNHK-GHPMNEEQIA-YICR-------EVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAP

EVVEM-----SGVSASSDIWSVGCTVIELLTCVPPYYDLQPMPALFRIV--QDERPPIPE----HLSPGLTDFLHQCFQKDAKLRPDAKTLLKHSWI
||..      .|    .||||.| | ||...  |||.|..|| |.|.|   | . |.  .    . || . ||. .| ||| . || |. ||||..|
EVIQCMEGPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase NPK1-2.AA S_TKc 20-282 32 7.4e-95 322.36 SMART 1-231 (231) Show / Hide 
Range on Protein: 20-282
Range on HMM: 1-231/231
Sequence Identity: 32% (91 aa)

YIIGDEIGKGAYGRVYKGLDLENGDFVAIKQVSLENIPPEDLASIMQEIDLLKNLNHKNIVKYRGSIKTKTHLYIILEYVEN--GSLASIVKPNKFGA--
| |...|||||.|.|||. . . |  ||||...          .|..||..||. .|.||||. ... . .|||...||...  |.| .. | .. .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--FPESLVAVYIAQALLTRYSQVLEGLAYLHEQGVIHRDIKGANILTTKEGFVKLADFGVATKLTEADVNTHSVVGTPYWMAPEVVEMSGVSA-SSDIWS
  |||  .. |..        |....|.|.|..|.||||.| .||| ..   .|..|||.|..|       ....|||..|||||.   | .  ..|.||
FPFPE-HARFYMY--------QICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWS

VGCTVIELLTCVPPYYDLQPMPALFRIVQDERPPIPEHLSPGLTDFLHQCFQKDAKLRPDAKTLLK-------HSWI
.||...|.|.  ||..    | ..|...           || . ||. .|.||| . || |  .|.       | |.
CGCILYEMLCGYPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase NPK1-2.AA YSK 20-282 39 1.7e-92 278.78 In-house 1-257 (257) Show / Hide 
Range on Protein: 20-282
Range on HMM: 1-257/257
Sequence Identity: 39% (106 aa)

YIIGDEIGKGAYGRVYKGLDLENGDFVAIKQVSLENIPPEDLASIMQEIDLLKNLNHKNIVKYRGSIKTKTHLYIILEYVENGSLASIVKPNKFGAFPES
. . . ||.| .| |||| |   .  |||| . ||    ..   | |||  |  .   .| || ||    | | || ||   ||...  ||   |.|.|.
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHA-EDEIEDIQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYVGQFDEK

LVAVYIAQALLTRYSQVLEGLAYLHEQGVIHRDIKGANILTTKEGFVKLADFGVATKLTEADVNTHSVVGTPYWMAPEVVEM--SGVSASSDIWSVGCTV
 .|. .          .| || |||.. .|||||| ||.| ...| |||.||||| ..|.        |||||||||||.    |.  .  ||||.| | 
YIAIILR--------EILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVICQEVSYYDFKADIWSLGITA

IELLTCVPPYYDLQPMPALFRIVQDERPPIPE-HLSPGLTDFLHQCFQKDAKLRPDAKTLLKHSWI
.|...  |||.|. || ..|.|. .. |     . |  . .|   |  || . || ||.||||. |
YEMAKGEPPYCDYHPMRVMFLIPKNNPPKLEGRSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase NPK1-2.AA Pkinase 20-282 28 6.8e-85 293.14 Pfam 1-293 (293) Show / Hide 
Range on Protein: 20-282
Range on HMM: 1-293/293
Sequence Identity: 28% (88 aa)

YIIGDEIGKGAYGRVYKGLDLENGDFVAIKQVSLENIPPEDLASIMQ--EIDLLKNLNHKNIVKYRGSIKTKTHLYIILEYVENG----SLASIVK---P
| ||  ||.|..|.|||. .  .|. ||.|....... .. . .     || ..|.|||.|||.....  .|.|.|...||.|.|    .|.....    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NKFGAFPESLVAVYIAQALLTRYSQVLEGLAYLHEQGVIHRDIKGANILTTKEGFV----KLADFGVATKL-TEADVNTHSVVGTPYWMAPEVVE-MSGV
..|  |.|  .  |.         |.|.||.|.|..|.||||.| .|||  ..| .    |..|||.| .. .  .. .....|||..|||||.   .. 
GCFY-FSEWECKFYMY--------QILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYY

SASSDIWSVGCTVIELLTCVPPYYDL----QPMPALFRIVQDERPPIPEHLS-----------------------PGLTDFLHQCFQKDAKLRPDAKTLL
. ..|.||.||...|.|.  ||...       .  ...|... .||.... .                       . . ||.  |..|| | || |. .|
GPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQIL

KHSWI
.| |.
QHPWF
Kinase NPK1-2.AA PAKA 20-282 35 2.7e-74 253.12 In-house 1-260 (260) Show / Hide 
Range on Protein: 20-282
Range on HMM: 1-260/260
Sequence Identity: 35% (95 aa)

YIIGDEIGKGAYGRVYKGLDLENGDF--VAIKQVSLENIPPEDLASIMQEIDLLKNLNHKNIVKYRGSIKTKTHLYIILEYVENGSLASIVKPNK---FG
|   ..||.|| | ||.. ......   |||||  ..| |  .|  |. || ..|. .|||||.|  | . .  |....|| | |.|  ... .     .
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPKKEL--IINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCN

AFPESLVAVYIAQALLTRYSQVLEGLAYLHEQGVIHRDIKGANILTTKEGFVKLADFGVATKLTEADVNTHSVVGTPYWMAPEVVEMSGVSASSDIWSVG
 ..|. .| |. .       ..| || ..|....||||||  |||  ..| ||..||| .. ||. .    ..|||||||||||.     .   |||| |
YMDEGQIA-YVCR-------ECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQYDEKVDIWSLG

CTVIELLTCVPPYYDLQPMPALFRIVQDERPPI--PEHLSPGLTDFLHQCFQKDAKLRPDAKTLLKHSWI
  .||..   ||| .  |  |.. | .  .|.|  |. .|. . ||| .| ..| . |..|..||.|  .
IMAIEMIEGEPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase NPK1-2.AA MEKK15 20-282 41 1.7e-73 250.51 In-house 1-264 (264) Show / Hide 
Range on Protein: 20-282
Range on HMM: 1-264/264
Sequence Identity: 41% (113 aa)

YIIGDEIGKGAYGRVYKGLDLENGDFVAIKQVSLENIPPE----DLASIMQEIDLLKNLNHKNIVKYRGSIKTKTHLYIILEYVENGSLASIVKPNKFGA
.  |. .|||||| || ||  . |  .|.||| |..|  |    .   .  |.|||| | ||||| | |       . | ...|  ||..||.  |.||.
WKKGNILGKGAYGTVYCGL-TNTGQLIAVKQVELDEIDKEKAKQQYRKLQEEVDLLKTLKHKNIVAYLGVCLEDNVVNIFMQFVPGGSISSII--NRFGP

FPESLVAVYIAQALLTRYSQVLEGLAYLHEQGVIHRDIKGANILTTKEGFVKLADFGVATKLTEADVN-TH-----SVVGTPYWMAPEVVEMSGVSASSD
 .|     |          |.|.| .||||  |.||||||.|..    | .|| ||| | .|. . .| ||     |. ||||||||||.  .|    ||
LDEMVFCKYTK--------QILQGVQYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCAKRLCWQGINRTHSDMLKSMRGTPYWMAPEVIMETGYGRKSD

IWSVGCTVIELLTCVPPYYDLQPMPALFRIVQD--ERPPIPEHLSPGLTDFLHQCFQKDAKLRPDAKTLLKHSWI
|||.|||| |. |  ||. |...| |.| |       |..|.. |    .| . |  .| . || |  ||||..|
IWSIGCTVFEMATRKPPWADMDRMAAMFYIGAHRDPMPQLPVKFSEDARMFVRMCLTRDQHERPTASQLLKHPFI
Kinase NPK1-2.AA NEK 20-282 30 1.8e-70 240.43 In-house 1-286 (286) Show / Hide 
Range on Protein: 20-282
Range on HMM: 1-286/286
Sequence Identity: 30% (92 aa)

YIIGDEIGKGAYGRVYKGLDLENGDF-----VAIKQVSLENIPPEDLASIM-QEIDLLKNLNHKNIVKYRGSIKTKT--HLYIILEYVE-NGSLASIVKP
| |  .||.|..|.|||  . ..|.      ...|.....|  ...    . .|. .|| |.| |||||. |.  .   .|.|. || | .| |.  .| 
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

-NKFG----AFPESLVAVYIAQALLTRYSQVL-------EGLAYLHEQ-----GVIHRDIKGANILTTKEG----FVKLADFGVATKLTEADV-NTHS-V
 .|       |.|.               |..        .| |.|..      ..||||| .||  ||..    .||. |||.. |. . ..   .. .
IKKQKQKGKYFEEE---------------QIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGIS-KVLNHTTDMAYTTQ

VGTPYWMAPEVVEMSGVSASSDIWSVGCTVIELLTCVP--PYYDLQ--PMPALF-RIVQD-ERPPIPEH--LSPGLTDFLHQCFQKDAKLRPDAKTLLKH
|||||.|.|||..  . .  |||||.|| . |. |. |  | .  .   ||.|. .|..  . ||||.|   |. | ....|..||| ..||... .|..
VGTPYYMSPEVCQNKPYNNKSDIWSLGCVLYEMCTLKPKHPFEA-WDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEM

SWI
. |
PFI
Kinase NPK1-2.AA MEKK2 20-282 40 8.7e-69 234.83 In-house 1-262 (262) Show / Hide 
Range on Protein: 20-282
Range on HMM: 1-262/262
Sequence Identity: 40% (110 aa)

YIIGDEIGKGAYGRVYKGLDLENGDFVAIKQVSLENIPPE---DLASIMQEIDLLKNLNHKNIVKYRGSIKTKT--HLYIILEYVENGSLASIVKPNKFG
.  |  .|.||.||||   | . |  .|.|||  ..  ||   .  .. .||.||||| |. ||.| | .. .    | | .||.  ||.   .|   .|
WRRGKLLGQGAFGRVYVCYDVDTGRELAVKQVQFDPDNPETRKEVQALECEIQLLKNLQHERIVQYYGCLRDNQEKTLSIFMEYMPGGSVKDQLK--AYG

AFPESLVAVYIAQALLTRYSQVLEGLAYLHEQGVIHRDIKGANILTTKEGFVKLADFGVATKLTEADVNT---HSVVGTPYWMAPEVVEMSGVSASSDIW
|  |.    |      ||  |.|||..|||.. ..||||||||||    | |||.||| ...|    .     .|| ||||||.|||..  |     |.|
ALTETVTRKY------TR--QILEGMHYLHDHMIVHRDIKGANILRDSSGNVKLGDFGASKRLQTICMHITGMKSVTGTPYWMSPEVINGEGYGRKADVW

SVGCTVIELLTCVPPYYDLQPMPALFRI-VQDERPPIPEHLSPGLTDFLHQCFQKDAKLRPDAKTLLKHSWI
|.||||.|.||  ||. .   | |.|.|  |.  | .|.|.|    |||..||..  . || |. ||.| ..
SIGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLPQHVSQHARDFLKRCFVEIKQDRPSAEELLRHHFV
Kinase NPK1-2.AA TyrKc 20-282 23 1.1e-34 122.45 SMART 1-280 (280) Show / Hide 
Range on Protein: 20-282
Range on HMM: 1-280/280
Sequence Identity: 23% (70 aa)

YIIGDEIGKGAYGRVYKGLDLENGDFVAIKQVSLENIPPEDLASIMQEIDLLKNL--NHKNIVKYRGSIKTK-------THLYIILEYVENGSLASIVKP
   |...| ||.|.||||        ||.| .  .      .. .|.|. ....|  .|.|||.  | . ..         |.|..||...|.| .  . 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

NKFGAFPESLVAVYIAQALLTRYS-QVLEGLAYLHEQGVIHRDIKGANILTTKEGFVKLADFGVATKLTEA-------DVNTHSV-VGTP-----YWMAP
..            .  . |  .. |. .| .|||....||||.   |.| .... || .||| . ....        |. ...   |.       ||||
HRPK----------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAP

EVVEMSGV-SASSDIWSVGCTVIELLT-CVPPYYD-----LQPMPALFRIVQDERPPIPEH--------LSPGLTDFLHQCFQKDAKLRPDAKTLLKHSW
|.  . |. .  ||.|| | .  |..| . .||..     . .  .. .. | .|.|.|..         .. . .   || . |.. ||  ...  |. 
ECI-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HEC

I
.
F
Kinase NPK1-2.AA Pkinase_Tyr 20-104 30 4.7e-19 65.15 Pfam 1-94 (270) Show / Hide 
Range on Protein: 20-104
Range on HMM: 1-94/270
Sequence Identity: 30% (29 aa)

YIIGDEIGKGAYGRVYKGLDL----ENGDFVAIKQVSLENIPPED--LASIMQEIDLLKNL-NHKNIVKYRGSIK-TKTH--LYIILEYVENGSL
 ..| ..|.||.|.||||       ...  ||.| .  |.  .|.  ... |.|. ..|.| .|.|||.. | .   . .  .||..||...|.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDL
Kinase NPK1-2.AA Pkinase_Tyr 138-279 29 5e-18 61.69 Pfam 122-269 (270) Show / Hide 
Range on Protein: 138-279
Range on HMM: 122-269/270
Sequence Identity: 29% (44 aa)

EGLAYLHEQGVIHRDIKGANILTTKEGFVKLADFGVATKLTEADVNTHSVVG---TPY-WMAPEVVEMSGVSASSDIWSVGCTVIELLT-CVPP-YYDLQ
.|..||.... ||||.   |.| |....|| .||| |  ... |   . . |    |  |||||.   .  .  ||.|| | .  |..| .  | |... 
KGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMS

PMPALFRI-VQDERPPIPEHLSPGLTDFLHQCFQKDAKLRPDAKTLLKH
.   . .|  . .| |.||. .. . | . || ..|.. ||  . .. .
NEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQ