Gene IRAK-0_n-1 (S.moellendorffii)

IRAK-0_n-1

Species: S.moellendorffii
Alias: IRAK-0_n-1
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAK-0

Sequence

Name Sequence Type Origin Length Description Download
IRAK-0_n-1.AA Protein None 614 None Fasta, JSON
IRAK-0_n-1.NA RNA None 1845 None Fasta, JSON
IRAK-0_n-1.kin_dom Protein Kinase Domain None 203 None Fasta, JSON

Protein domain

Protein domains of IRAK-0_n-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase IRAK-0_n-1.AA TKL 298-567 21 1.2e-66 227.7 In-house 1-364 (364) Show / Hide 
Range on Protein: 298-567
Range on HMM: 1-364/364
Sequence Identity: 21% (84 aa)

IGQGGYGNVYKGVLKD---------GTVVALKRFKN--CSPAGD-------------------------EGFVHEMEMISSVRHKNLAPLLGWCIGSSR-
||.||.| ||||...          |..|| |.||   ..   .                         . .. |. |.|. || |. ...| |. ..  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-------SEGHQRIIVYEFMSNGS-LDDHLFGKFKKNLDWPTRQKIAIGTAKGLAYLHN-----GAQPAIIHRDIKGGNILLDSEFN-------------
       ..  |  ||.|....|| |....         |. | ..|...|.|..|||.     .  |.|||||.|  |||.|. ..             
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

-AKVADFGLAKFA----PEGMTHMTTG--------------VAGTQGYVAPEYVLYN----------------QLTDRSDVYSFGIVFLELLSGRKALVH
 .|..||||..|        .| .|..              . || .. |||    .                . . ..||||||||. |.|....    
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR----

TPASDTPVPIADWAWSVMK---------ETRIVDILQQPMDK--------LGDEEVMESFILVALLCAHPQVAYRPSMAQVVKML
        | .|   . |.         . .... |. |..            . ...|..  .  | ..    |||. ...| |
--------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase IRAK-0_n-1.AA IRAK 292-496 39 2e-60 207.08 In-house 1-223 (317) Show / Hide 
Range on Protein: 292-496
Range on HMM: 1-223/317
Sequence Identity: 39% (91 aa)

FHRTTLIGQGGYGNVYKGVLKDGT-VVALKRFKN---CSPAG-DEGFVH---EMEMISSVRHKNLAPLLGWCIGSSRSEGHQRIIVYEFMSNGSLDDHLF
||.  .||.||.| ||.|..|  | ..| |..|.    |. . .. |     |..  .. ||.|. ||.| |.     |. .   ||..|.|||| | | 
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCT-----ERQCHCLVYPYMPNGSLEDRLW

GKF-KKN---LDWPTRQKIAIGTAKGLAYLHNGAQPA--IIHRDIKGGNILLDSEFNAKVADFGLAKF---AP--EGMTH---MTTGVAGTQGYVAPEYV
.         | |..| .|..|||.|. .||. ..|.  |||.|||  |||||  |..| .||||. |   |.  |  |    ||  | ||  | .||. 
CQDGQCPPKPLSWHQRCSICWGTACGIQFLHQ-NHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFI

L--YNQLTDRSDVYSFGIVFLELLSGRKA
     ||| ..|||||||| ||.|.|..|
RDPQGQLTKKTDVYSFGIVLLEVLTGCRA
Kinase IRAK-0_n-1.AA Pkinase 292-494 26 8.2e-44 156.0 Pfam 1-209 (293) Show / Hide 
Range on Protein: 292-494
Range on HMM: 1-209/293
Sequence Identity: 26% (59 aa)

FHRTTLIGQGGYGNVYKGVLKDGTV-VALKRFKNCSPAGDEG--FVH--EMEMISSVRHKNLAPLLGWCIGSSRSEGHQRIIVYEFMSNG----SLDDHL
.|.   ||.|..| |||.. |.    ||.|..| ..   ..    ..  | ..  ...|.|   |..|.       .    .| |.. .|    .| |..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-----KDHIYMVMEYCEGGLYVMDLFDYI

FGKFKKNL--DWPTRQKIAIGTAKGLAYLHNGAQPAIIHRDIKGGNILLDSEFNA----KVADFGLAK-FAPEGMTHMTTGVAGTQGYVAPEYVL-YNQL
 .. ....  .. . ....  ...||.|.|.     |||||.|  |||.|.. .     |..|||||| |  .   . .|...|| .|.||| .. ..  
STWRHGCFYFSEWECKFYMYQILRGLEYCHS-M--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYY

TDRSDVYSFGIVFLELLSGR
. ..|..|.|... |.|.||
GPKVDMWSCGCILYEMLCGR
Kinase IRAK-0_n-1.AA TKL-Unique 294-493 32 5e-42 145.94 In-house 1-224 (290) Show / Hide 
Range on Protein: 294-493
Range on HMM: 1-224/290
Sequence Identity: 32% (73 aa)

RTTLIGQGGYGNVYKGVLKDGTVVALKRFK-NCSPAGD--EGFVHEMEMISSVR-HKNLAPLLGWCIGSSRSEGHQRIIVYEFMSNGSLDDHLFG-----
   .||.||||.||||. . |. ||.|.|. | ..  .  . |  |   ..  . |.|.  . |.|.    .... ..|| |... |||.|.|       
FWNKIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPN-MCIVMEYCPGGSLYDVLHQNNNNN

---KFKKNLDWPTRQKIAIGTAKGLAYLHNGAQPAIIHRDIKGGNILLDSE-----FNAKVADFGLAKFAPEGMTHMTT--------GVAGTQGYVAPEY
   . ...|..  | |.||  |.|. |||.   | |||||.|  |.|.|..     .|.|..||||.||.   ..  ..        .. |.  ..||| 
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEV

VLY--NQLTDRSDVYSFGIVFLELLSG
     .| .  |||||||||  |....
LRMNFCQYSEKSDVYSFGIVLWEIATR
Kinase IRAK-0_n-1.AA Dicty4 292-491 32 5.4e-39 127.79 In-house 1-211 (277) Show / Hide 
Range on Protein: 292-491
Range on HMM: 1-211/277
Sequence Identity: 32% (71 aa)

FHRTTLIGQGGYGNVYKGVLKDGTVVALKRF--KNCS--PAGDEGFVHEMEMISSVRHKNLAPLLGWCIGSSRSEGHQRIIVYEFMSNGSLDDHLFGK--
  .. .||.|..| ||||  . |. || | .  .|     .  . | .| .  .. || |.  ..| |. . ||.     || |.|. |.|   |  .  
INIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACT-APRSHPGKMCIVTEYMPKGNL-YSLLHDKP

----FKKNLDWPTRQK---IAIGTAKGLAYLHNGAQPAIIHRDIKGGNILLDSEFNAKVADFGLAK-FAPEGMTHM-TTGVAGTQGYVAPEYVLYNQL-T
     .. ||||.. .   .|. .|.|...|| .  | |||||.|  |.| |  ...||.||||.. . .. .    .....|| ...||| |. .|  .
SEQQQSIKLDWPLIKRAMRMAFDAARGMNWLH-CCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPE-VMMHQPYN

DRSDVYSFGIVFLELL
  .||||||||  |.|
EKADVYSFGIVLWEIL
Kinase IRAK-0_n-1.AA RIPK 298-496 28 1.1e-37 126.0 In-house 1-227 (290) Show / Hide 
Range on Protein: 298-496
Range on HMM: 1-227/290
Sequence Identity: 28% (65 aa)

IGQGGYGNVYKGVLKDGTVVALKRFKNCSPAG-------DEGFVHEMEMISSVRHKNLAPLLGWCIGSSRSEGHQ-RIIVYEFMSNGSLDDHLFGKFK--
.| || | |.| . ..  ....|  |.| .          .    | ..  . |...  |..| |.        .   || |.| |||| . |  | .  
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

-KNLDWPTRQKIAIGTAKGLAYLHNGAQPAIIHRDIKGGNILLDSEFNAKVADFGLAKFAPEG--MT--------HMTTGVA--GTQGYVAPEYVL---Y
 . . || |  .   .. |  |||.  .| ||||| | .|||.|..|..|.||||||..      ..          ...    ||  | .||  .    
HHPDPWPLRCRMIHEISCGMCYLHS-MNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNK

NQ---LTDRSDVYSFGIVFLELLSGRKA
.     |  .|||||.||  |.|.....
KPIKVVTPKYDVYSFAIVMWEVLTQKHP
Kinase IRAK-0_n-1.AA LRRK 292-494 25 5.5e-37 128.37 In-house 1-279 (351) Show / Hide 
Range on Protein: 292-494
Range on HMM: 1-279/351
Sequence Identity: 25% (74 aa)

FHRTTLIGQGGYG-NVYKGVLKD---------------------------GTVVALKRFKNC----------------------------------SPAG
. .  .||.||.| .||.. ...                           .. || | .. .                                  ..  
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

DEGFVHEMEMISSVRHKNLAPLLGWCIGSSRSEGHQRIIVYEFMSNGSLDDHLFGKFKKN-------LDWPTRQKIAIGTAKGLAYLHNGAQPAIIHRDI
   | ||. ..|. .| |. .|.| ||       | ...| |....|.|...|. |..         ..| ...|||.  |||..|||. . | ||||| 
FREFRHEVWIMSHLNHPNIVSLKGFCI-------HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHS-HNPPIIHRDL

KGGNILL---D---------SEFNAKVADFGLAK-FAPEGMTHM--TTGVAGTQGYVAPEYVLYN---QLTDRSDVYSFGIVFLELLSGR
|  ||||   .          . .||.||||.   |     .||  . |. |. |..||| . ||   . |. .|.||||..  |||...
KSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMF---QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQ
Kinase IRAK-0_n-1.AA STE 292-494 21 5.8e-37 128.09 In-house 1-265 (359) Show / Hide 
Range on Protein: 292-494
Range on HMM: 1-265/359
Sequence Identity: 21% (58 aa)

FHRTTLIGQGGYGNVYKGVLKD----------------GTVVALKRFK--NCSP---------------AGDEGFVHEMEMISSVR--HKNLAPLLGWCI
. .   ||.|..| |||.. ..                |...| |. .  ||..                  . . .|... .  .  |.|    .| ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

GSS--RSEGHQRIIVYEFMSNGSLDDHLFGKFKKNLD------------WPTRQKIAIGTAKG-LAYLH-NGAQPAIIHRDIKGGNILLDSEFNAKVADF
  .   .....  |. |.|..||||| .  |.... .             .   .|.  . || |.||| ..    |||||||..||||     .| .||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH----IIHRDIKPANILL-----VKLCDF

GLAK-FAPEGM------------TH--MTTGVAGTQGYVAPEYVLY------NQLTDRSDVYSFGIVFLELLSGR
|... .....             |   ... ..||. . ||| ..       .. . ..|..|.|.. .|.. |.
GVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK
Kinase IRAK-0_n-1.AA Pkinase_Tyr 292-486 28 8e-36 121.95 Pfam 1-203 (270) Show / Hide 
Range on Protein: 292-486
Range on HMM: 1-203/270
Sequence Identity: 28% (60 aa)

FHRTTLIGQGGYGNVYKGVLK-----DGTVVALKRFKNCSPAGD---EGFVHEMEMISSV-RHKNLAPLLGWCIGSSRSEGHQ--RIIVYEFMSNGSLDD
 .    .|.| .|.||||..|     ... || |  |. .   .   | | .|... ..  .|.|.  |.| |.    ..| .   .|| |.| .|.|.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCT----DQGEPNQIYIVMEYMPHGDLLD

HLFGK--FKKNLDWPTRQKIAIGTAKGLAYLHNGAQPAIIHRDIKGGNILLDSEFNAKVADFGLAKFA-PEGMT-HMTTGVAGTQGYVAPEYVLYNQLTD
.|  .   |..|. ..  ....  |||..||..     .||||.   |.|..... .|..|||||.   ...   ....|        |||   |.  | 
YLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTT

RSDVYSFGIV
 |||.|||..
KSDVWSFGVL
Kinase IRAK-0_n-1.AA S_TKc 292-567 19 5.1e-34 120.26 SMART 1-231 (231) Show / Hide 
Range on Protein: 292-567
Range on HMM: 1-231/231
Sequence Identity: 19% (58 aa)

FHRTTLIGQGGYGNVYKGVLKD-GTVVALKRFKNCSPAGDEGFVHEMEMISSVRHKNLAPLLGWCIGSSRSEGHQRIIVYEFMSN--GSLDDHLFGKFKK
..   .||.|..| |||.. |. | .||.|. |       | .  |... .. .|.|.  |....        .   .| |....  |.| |..  . ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD------DHLYMVMEYCDGDLGDLFDYIKKRGRH

N----LDWPTRQKIAIGTAKGLAYLHNGAQPAIIHRDIKGGNILLDSEFNAKVADFGLAKFAPEGMTHMTTGVAGTQGYVAPEYVLYNQLTD-RSDVYSF
     ..  . ....  ....|.|.|.  .  |||||.|  |||||.  . |..|||||..         | . ||  |.||| .   . .  ..|..|.
GLRFPFPE-HARFYMYQICCALEYCHS--H-GIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSC

GIVFLELLSGRKALVHTPASDTPVPIADWAWSVMKETRIVDILQQPMDKLGDEEVMESFILVALLCAHPQVAYRPSMAQVVK---------ML
|... |.|. .. . .                   . .. ...             ....     | .   . ||.  .. .          .
GCILYEMLC-GYPPFP------------------QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase IRAK-0_n-1.AA MLK 292-494 25 1.3e-33 114.05 In-house 1-233 (291) Show / Hide 
Range on Protein: 292-494
Range on HMM: 1-233/291
Sequence Identity: 25% (63 aa)

FHRTTLIGQGGYGNVYKGVLKDGT----VVALKRFK---NCSPAG----DEGFVHEMEMISSVRHKN----LAPLLGWCIGSSRSEGHQRIIVYEFMSNG
.   . || |..| |.||. .  .    .||.||..     . .     .. |  | .  . ..|.|      ...| |.    .....  || |....|
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCL----QPPCHFCIVMEYCEGG

SLDDHLFG-KFKKN-----------LDWPTRQKIAIGTAKGLAYLHNGAQPAIIHRDIKGGNILLDS------EFNAKVADFGLAKFAPEGMTHM---TT
|| . | | . | .            |     ..|   |.|..|||. |...|||||.|  |||.|       . ..|..|||....    ...|    .
SLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRD----WHQMCTNMM

GVAGTQGYVAPEYVL----YNQLTDRSDVYSFGIVFLELLSGR
. |||  . ||| |.     .. .  .||.|.|.|. |.|...
SNAGTYAWMAPE-VIQQFRCEKYSEKCDVWSWGVVLWEMLTRE
Kinase IRAK-0_n-1.AA DRK 298-491 36 2.6e-31 103.35 In-house 7-196 (258) Show / Hide 
Range on Protein: 298-491
Range on HMM: 7-196/258
Sequence Identity: 36% (72 aa)

IGQGGYGNVYKGVLKDGTVVALKRFKNCSPA-GD--EGFVHEMEMISSVRHKNLAPLLGWCIGSSRSEGHQRIIVYEFMSNGSLDDHLFGKFKKNLDWPT
|| |.|| |. |    || || |. .|      .    |  | ....  || |    .| |  ..        |. |.|. |||   |    .  .||| 
IGRGNYGEVFRGTWR-GTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPP-----DICICMEYMPRGSLYNILHDE-SIEMDWPL

RQKIAIGTAKGLAYLHNGAQPAIIHRDIKGGNILLDSEFNAKVADFGLAK-FAPEGMTHMTTGVAGTQGYVAPEYVLYNQL-TDRSDVYSFGIVFLELL
. ....  |||. |||.   | ||||| |  | | |  .  |||||||.  |        .    || . .||| || ||  |   |||||.||  |..
MKQMMFDCAKGMIYLHC-CNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPE-VLRNQRYTEKADVYSFAIVLWECV
Kinase IRAK-0_n-1.AA CZAK 292-494 30 2.1e-30 107.32 In-house 1-219 (279) Show / Hide 
Range on Protein: 292-494
Range on HMM: 1-219/279
Sequence Identity: 30% (68 aa)

FHRTTLIGQGGYGNVYKGVLKDGTVVALK-----RFKNCSPA-GDEGFVHEMEMISSVRHKNLAPLLGWCIGSSRSEGHQRIIVYEFMSNGSLDDHLFGK
.     |||| .| |||.. . |..||.|     .|.| .     . |  |   .|  .| |    || |  |   .   . || |.|  |||.  |  .
LKFGQTIGQGFFGEVYKAYWR-GKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGAC--SEDGP-NHHCIVMEWMGGGSLRRLLTDH

FKKNLDWPT-RQKIAIGTAKGLAYLHNGAQP-AIIHRDIKGGNILLDSEFN-------------AKVADFGLAKFAPEGMTHMTTGVAGTQGYVAPEYVL
.   .  |  . ..||  |.|  |||    |  |.|||    |||||.                .|..|||| .   |. . ||  . |   . |||   
YFYHKQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTM-GCLCWMAPECFK

YNQLTDRSDVYSFGIVFLELLSGR
    |  .||||||..  ... ..
GENYTEKVDVYSFGMILWCIITCD
Kinase IRAK-0_n-1.AA TyrKc 292-567 22 5.7e-18 66.94 SMART 1-280 (280) Show / Hide 
Range on Protein: 292-567
Range on HMM: 1-280/280
Sequence Identity: 22% (68 aa)

FHRTTLIGQGGYGNVYKGVLKDGTVVALKRFKNCSPAGDEGFVHEMEMISSV--RHKNLAPLLGWCIGSSRSEG---HQRIIVYEFMSNGSLDDHLFGKF
 .    .| | .| ||||..|  . || |  |...    | | .|... ...  .|.|.  |.| |. ..|      ..  || |.|..|.|.|.|  . 
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN-FMYIEPLMIVMEYMPHGDLKDYLRKHR

KKNLDWPTRQKIAIGTAKGLAYLHNGAQPAIIHRDIKGGNILLDSEFNAKVADFGLAKFAPEG--------MTHMTT--GVA--GTQGYVAPEYVLYNQL
.| | ...  ....  |.| .|||      .||||.   |.|..... .|..||||...  ..        . ....  |          |||   |.  
PK-LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

TDRSDVYSFGIVFLELLSGRKALVHTPASDTPVPIADWAWSVMKETRIVDILQQPMDKLGDEEVM------ESFILVALLCAHPQVAYRPSMAQVVKML
|  |||.|||..  |...  .     ..   ... ..    |..  .  . . || . .   . |      .    . . | | . . ||....... .
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQE----VIEYVKQGYRMPQPPNDY---P-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase IRAK-0_n-1.AA DRK 557-569 46 0.004731 6.22 In-house 246-258 (258) Show / Hide 
Range on Protein: 557-569
Range on HMM: 246-258/258
Sequence Identity: 46% (6 aa)

RPSMAQVVKMLEN
|||| .... || 
RPSMQECLERLEA
Kinase IRAK-0_n-1.AA Dicty4 557-569 33 0.00512 6.1 In-house 263-277 (277) Show / Hide 
Range on Protein: 557-569
Range on HMM: 263-277/277
Sequence Identity: 33% (5 aa)

RPSMAQVVKM--LEN
|||......   || 
RPSFEEIIQRRILEH
Kinase IRAK-0_n-1.AA IRAK 535-567 24 0.005223 6.7 In-house 285-317 (317) Show / Hide 
Range on Protein: 535-567
Range on HMM: 285-317/317
Sequence Identity: 24% (8 aa)

DEEVMESFILVALLCAHPQVAYRPSMAQVVKML
.... ...  .|. |.|  .. |..||.|.. |
PPNMEKEMCQCACCCGHHRANRRCDMAWVMQQL
Kinase IRAK-0_n-1.AA MLK 557-567 54 0.0409 3.29 In-house 281-291 (291) Show / Hide 
Range on Protein: 557-567
Range on HMM: 281-291/291
Sequence Identity: 54% (6 aa)

RPSMAQVVKML
|||..|.|. |
RPSFRQIVQHL
Kinase IRAK-0_n-1.AA LRRK 557-569 46 0.072837 2.36 In-house 339-351 (351) Show / Hide 
Range on Protein: 557-569
Range on HMM: 339-351/351
Sequence Identity: 46% (6 aa)

RPSMAQVVKMLEN
||.. |.|| |. 
RPHFSQIVKRLSQ