Gene IRAK-0_bq (S.moellendorffii)

IRAK-0_bq

Species: S.moellendorffii
Alias: IRAK-0_bq
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAK-0

Sequence

Name Sequence Type Origin Length Description Download
IRAK-0_bq.AA Protein None 492 None Fasta, JSON
IRAK-0_bq.NA RNA None 1479 None Fasta, JSON
IRAK-0_bq.kin_dom Protein Kinase Domain None 59 None Fasta, JSON

Protein domain

Protein domains of IRAK-0_bq.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
DUF26 IRAK-0_bq.AA DUF26 80-133 38 4.3e-21 65.74 Pfam 1-55 (55) Show / Hide 
Range on Protein: 80-133
Range on HMM: 1-55/55
Sequence Identity: 38% (22 aa)

VYGFIQCRGDISAQECSSCARSAVQIL-NSTCVRNSTKGGRIHPGNCFLRYE-DH-F
|||  |||.|.|.. |..| ..||. .  ..|  .. .||||.   |.|||. .  |
VYGMAQCRPDLSPSDCRDCLATAVRQMLPQCC--PNRQGGRIWYDWCYLRYSDYPNF
DUF26 IRAK-0_bq.AA DUF26 194-246 36 2.6e-13 42.27 Pfam 1-55 (55) Show / Hide 
Range on Protein: 194-246
Range on HMM: 1-55/55
Sequence Identity: 36% (20 aa)

AYALGQCIPDLSAADCASCLAAAENAI-ASTCRGGGGGVCYYSSCTLFFQRSK-F
.|...||.||||..||..|||.| . . ...|..  ||. .| .| | .  .. |
VYGMAQCRPDLSPSDCRDCLATAVRQMLPQCCPNRQGGRIWYDWCYLRYSDYPNF
Kinase IRAK-0_bq.AA IRAK 335-382 37 1.3e-10 34.03 In-house 1-56 (317) Show / Hide 
Range on Protein: 335-382
Range on HMM: 1-56/317
Sequence Identity: 37% (21 aa)

FSDDHKLGEGGFGAVYKGTFSDGT-EIAIKKL----SVASKQWEQQFLN---EVKV
|. |...|||||| ||.| ..  |   |.|||    ..  .. .|.|.    |.||
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKV
Kinase IRAK-0_bq.AA LISK 340-383 32 1.4e-10 30.41 In-house 1-50 (296) Show / Hide 
Range on Protein: 340-383
Range on HMM: 1-50/296
Sequence Identity: 32% (16 aa)

KLGEGGFGAVYKGTFS-DGTEIAIKKLS-----VASKQWEQQFLNEVKVI
..|.|.|| |||||   .|...|||...     .  .  .  .| ||...
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMM
Kinase IRAK-0_bq.AA TKL 341-389 19 1.4e-10 34.31 In-house 1-86 (364) Show / Hide 
Range on Protein: 341-389
Range on HMM: 1-86/364
Sequence Identity: 19% (17 aa)

LGEGGFGAVYKGTFSD---------GTEIAIKKLSVASKQWE---------------------------QQFLNEVKVIGSL-HSN
.|.|||| ||||..           |...|.||... . . .                           ... .|.... .| | |
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPN
Kinase IRAK-0_bq.AA Src 335-392 29 2.3e-09 27.95 In-house 1-57 (255) Show / Hide 
Range on Protein: 335-392
Range on HMM: 1-57/255
Sequence Identity: 29% (17 aa)

FSDDHKLGEGGFGAVYKGTFSDGTEIAIKKLSVASKQWEQQFLNEVKVIGSLHSNRLL
.    |||.| || |..|.. . |. |.| |. ..    ..|| | ..  .|  ..|.
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGT-MSPEAFLQEAQIMKKLRHEKLV
Kinase IRAK-0_bq.AA STE20 335-382 22 9.4e-09 28.42 In-house 1-57 (288) Show / Hide 
Range on Protein: 335-382
Range on HMM: 1-57/288
Sequence Identity: 22% (13 aa)

FSDDHKLGEGGFGAVYKGTF-SDGTE----IAIKKLSVASK----QWEQQFLNEVKV
. . .|.|.|..|.|||..  . | .    .||||... ..    . ..  ..|. .
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISI
Kinase IRAK-0_bq.AA SFK-Src 338-382 40 2e-08 20.43 In-house 4-47 (259) Show / Hide 
Range on Protein: 338-382
Range on HMM: 4-47/259
Sequence Identity: 40% (18 aa)

DHKLGEGGFGAVYKGTFSDGTEIAIKKLSVASKQWEQQFLNEVKV
  |||.| || |.||.  . ||.|.| |  ..   .. ||.|  |
EKKLGSGQFGDVWKGRWNNTTEVAVKTLKPGAMS-AEEFLQEAQV
Kinase IRAK-0_bq.AA TKL-Unique 337-388 39 2.1e-08 25.97 In-house 1-55 (290) Show / Hide 
Range on Protein: 337-388
Range on HMM: 1-55/290
Sequence Identity: 39% (22 aa)

DDHKLGEGGFGAVYKGTFSDGTEIAIKKLSV---ASKQWEQQFLNEVKVIGSLH-S
.  |.||||.|.||||..  |...|||....    |.. .| | |||...  || .
FWNKIGEGGYGQVYKGKW-RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYH
Kinase IRAK-0_bq.AA Fer 335-379 31 6.2e-07 19.78 In-house 1-58 (283) Show / Hide 
Range on Protein: 335-379
Range on HMM: 1-58/283
Sequence Identity: 31% (18 aa)

FSDDHKLGEGGFGAVYKG--TFSDGT---------EIAIKKL--SVASKQWEQQFLNE
. .. ||||| || ||||  |.  .          ... ||.  ..|.|   . |..|
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHE
Kinase IRAK-0_bq.AA LRRK 335-367 18 1e-06 19.72 In-house 1-61 (351) Show / Hide 
Range on Protein: 335-367
Range on HMM: 1-61/351
Sequence Identity: 18% (11 aa)

FSDDHKLGEGGFG-AVYKGTFSD---------------------------GTEIAIKKLSV
.    ..|.||||  ||.... .                           ....||||. .
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNR
Kinase IRAK-0_bq.AA Pkinase_Tyr 335-387 33 3e-06 21.8 Pfam 1-62 (270) Show / Hide 
Range on Protein: 335-387
Range on HMM: 1-62/270
Sequence Identity: 33% (21 aa)

FSDDHKLGEGGFGAVYKGTFS-----DGTEIAIKKL--SVASKQ-WEQQFLNEVKVIGSL-H
 . ..||||| || |||||       .... |.|.|  .  ..|   . |..|.|.  .| |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGH
Kinase IRAK-0_bq.AA Pkinase 335-389 24 1e-05 21.33 Pfam 1-61 (293) Show / Hide 
Range on Protein: 335-389
Range on HMM: 1-61/293
Sequence Identity: 24% (15 aa)

FSDDHKLGEGGFGAVYKGTFSDGTE-IAIKKLSVASKQW--EQQFLN--EVKVIGSL-HSN
.    |.|.|.|| |||..  .  .  |.|.... .. .  .|. ..  |...  .| | |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPN
Kinase IRAK-0_bq.AA TK 335-383 20 1.2e-05 14.06 In-house 1-92 (486) Show / Hide 
Range on Protein: 335-383
Range on HMM: 1-92/486
Sequence Identity: 20% (19 aa)

FSDDHKLGEGGFG---AVYKGTFSDG--------------------------TEIAIKKLSV---ASKQWEQQ-----------FLNEVKVI
    .||||| ||    ||||.  ..                          |. |.| |     .|.. ...           ||.|. ..
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEM
Kinase IRAK-0_bq.AA TK 418-440 30 3.6e-05 12.44 In-house 464-486 (486) Show / Hide 
Range on Protein: 418-440
Range on HMM: 464-486/486
Sequence Identity: 30% (7 aa)

IALMCTQASPQDRPSMSHVVAML
. ..| .. |.|||..| .. .|
LMQQCWHYDPEDRPTFSQLHEQL
Kinase IRAK-0_bq.AA Fer 418-441 36 0.000227 10.92 In-house 259-283 (283) Show / Hide 
Range on Protein: 418-441
Range on HMM: 259-283/283
Sequence Identity: 36% (9 aa)

IAL-MCTQASPQDRPSMSHVVAMLS
| . .| |. | |||.|.... .| 
IMMKQCWQKDPEDRPTMKEICQKLK
Kinase IRAK-0_bq.AA TKL 418-440 26 0.001413 8.76 In-house 342-364 (364) Show / Hide 
Range on Protein: 418-440
Range on HMM: 342-364/364
Sequence Identity: 26% (6 aa)

IALMCTQASPQDRPSMSHVVAML
.. .| .. |..|||.. ..  |
LMQDCWDHDPEKRPSFQEILKRL
Kinase IRAK-0_bq.AA LRRK 422-442 42 0.002321 7.73 In-house 331-351 (351) Show / Hide 
Range on Protein: 422-442
Range on HMM: 331-351/351
Sequence Identity: 42% (9 aa)

CTQASPQDRPSMSHVVAMLSG
| |. |..||..| .|  || 
CWQHDPKKRPHFSQIVKRLSQ
Kinase IRAK-0_bq.AA LISK 418-440 30 0.035735 2.63 In-house 274-296 (296) Show / Hide 
Range on Protein: 418-440
Range on HMM: 274-296/296
Sequence Identity: 30% (7 aa)

IALMCTQASPQDRPSMSHVVAML
....|.   | .||| ...|  |
LCFDCCKYDPKNRPSFKEIVQWL
Kinase IRAK-0_bq.AA Pkinase_Tyr 420-440 33 0.052086 7.43 Pfam 250-270 (270) Show / Hide 
Range on Protein: 420-440
Range on HMM: 250-270/270
Sequence Identity: 33% (7 aa)

LMCTQASPQDRPSMSHVVAML
..| .. |.|||..| .. .|
KQCWHYDPEDRPTFSEIHEQL