Gene IRAK-0_aj (S.moellendorffii)

IRAK-0_aj

Species: S.moellendorffii
Alias: IRAK-0_aj
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAK-0

Sequence

Name Sequence Type Origin Length Description Download
IRAK-0_aj.AA Protein None 690 None Fasta, JSON
IRAK-0_aj.NA RNA None 2073 None Fasta, JSON
IRAK-0_aj.kin_dom Protein Kinase Domain None 205 None Fasta, JSON

Protein domain

Protein domains of IRAK-0_aj.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
DUF26 IRAK-0_aj.AA DUF26 87-140 35 1.3e-23 73.31 Pfam 1-55 (55) Show / Hide 
Range on Protein: 87-140
Range on HMM: 1-55/55
Sequence Identity: 35% (20 aa)

VYGLIQCRGDITAQECSSCARSAFQLL-NSTCVRNSTKGGRVYLDHCFLRYE-DH-F
|||. |||.|.... |..| ..|.. .  ..|  .. .|||...| |.|||. .  |
VYGMAQCRPDLSPSDCRDCLATAVRQMLPQCC--PNRQGGRIWYDWCYLRYSDYPNF
DUF26 IRAK-0_aj.AA DUF26 199-251 36 1.2e-12 40.3 Pfam 1-55 (55) Show / Hide 
Range on Protein: 199-251
Range on HMM: 1-55/55
Sequence Identity: 36% (20 aa)

AYALGQCVPDLSAADCVACLAAAENVI-ASTCRGGGGGVCYYASCTLFFQGSK-F
.|...|| ||||..|| .|||.| . . ...|..  ||. .| .| | .  .. |
VYGMAQCRPDLSPSDCRDCLATAVRQMLPQCCPNRQGGRIWYDWCYLRYSDYPNF
Kinase IRAK-0_aj.AA IRAK 361-566 38 4.7e-63 215.78 In-house 1-222 (317) Show / Hide 
Range on Protein: 361-566
Range on HMM: 1-222/317
Sequence Identity: 38% (87 aa)

FSDDKKLGEGGFGAVYKGTFGDGTE--IAIKKL----SVSSKQGEQQFLN---EVKVIGSVQHRNLVRLLGCCVEGSERLLVYEFLKNNSLEKALLDDML
|. | ..|||||| ||.| . ..|.   |.|||    ..| .. .|.|.    |.||  . .| |.| |.| | |...  |||....| |||  |    .
FHKDNRIGEGGFGCVYRGQW-KNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLW--CQ

SEEETP-RLSLTTRYNILLGTARGLTYLHEDS-QIRIVHRDIKPSNILLDETFEAKISDFGLARLY---EEDEATEI---ITTKVAGTYGYMAPEYAF--
    .|  ||  .|  |..|||.|. .||...  . | |.|||..|||||. |..||.||||.|     .. |....   .| .| ||  ||.||.    
DGQCPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDP

HGHLSEKADVFTFGVVVLETLAGRK
 | |. | ||. ||.|.||.|.|..
QGQLTKKTDVYSFGIVLLEVLTGCR
Kinase IRAK-0_aj.AA TKL 367-640 19 2.3e-59 203.55 In-house 1-364 (364) Show / Hide 
Range on Protein: 367-640
Range on HMM: 1-364/364
Sequence Identity: 19% (77 aa)

LGEGGFGAVYKGTFGD---------GTEIAIKKLSVSSKQGE---------------------------QQFLNEVKVIGSVQHRNLVRLLGCCVEGSE-
.|.|||| ||||..           |...|.||... . . .                           ... .|.... . .| |.|...|.| ...  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RLLVYEFLKNNSLEKALLDDMLSEEETPRLSLTTRYNILLGTARGLTYLHEDS-----QIRIVHRDIKPSNILLDETFE---------
              .|.|. .. ||.  |.             .  | .. |..|||. ||| .         |.|||.|..|||.|| ..         
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNP

-----AKISDFGLARLYEEDEATEII----------------TTKVAGTYGYMAPEYAF----------------HGHLSEKADVFTFGVVVLETLAGRK
     .||.||||.|  ....  . .                | .. ||...||||                   ..  |||.||. ||.|  | |....
NADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR

NRDVTLPGPEQ-YLLE---------WAWQLHSDGLLANLLDP----KLVRSSSNEQERTLVQAIHIALMCTQASPQDRPSMSHVVAML
        |.. |  .         . . . .|  |  ...|    .. .      . .. . . .. .| .. |..|||.. ..  |
--------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHH-K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase IRAK-0_aj.AA Pkinase 361-565 26 7.8e-43 152.54 Pfam 1-209 (293) Show / Hide 
Range on Protein: 361-565
Range on HMM: 1-209/293
Sequence Identity: 26% (58 aa)

FSDDKKLGEGGFGAVYKGTFGDGTE-IAIKKLSVSSKQG--EQQFLN--EVKVIGSVQHRNLVRLLGCCVEGSERLLVYEFLKNN----SLEKALLDDML
.   .|.|.|.|| |||..  .  .  |.|.......    .|. ..  |...  ...| | |||.... ....  .| |.. .     .|   .     
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST---

SEEETPRL--SLTTRYNILLGTARGLTYLHEDSQIRIVHRDIKPSNILLDETFEA----KISDFGLARLYEEDEATEIITTKVAGTYGYMAPEYAF-HGH
  ..  ..  |  .  .... ..||| |.|.    .|.|||.||.|||.|.. .     ||.|||||....  .     .| ..||..|||||    . .
--WRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAPEVIRGGQY

LSEKADVFTFGVVVLETLAGR
 . |.|.. .|... | | ||
YGPKVDMWSCGCILYEMLCGR
Kinase IRAK-0_aj.AA TKL-Unique 363-560 30 3.2e-40 139.57 In-house 1-220 (290) Show / Hide 
Range on Protein: 363-560
Range on HMM: 1-220/290
Sequence Identity: 30% (67 aa)

DDKKLGEGGFGAVYKGTFGDGTEIAIKKLSV---SSKQGEQQFLNEVKVIGSVQ-HRNLVRLLGCCV----EGSERLLVYEFLKNNSLEKALLDDMLSE-
. .|.||||.|.||||..  |...|||....   ||.. .| | |||...   . | |.|.. | |.      ... .| |..  .|| . | .      
FWNKIGEGGYGQVYKGKW-RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

--EETPRLSLTTRYNILLGTARGLTYLHEDSQIRIVHRDIKPSNILLDET-----FEAKISDFGLARLYEEDEATEIITT------KVAGTYGYMAPEYA
  ..   |..  |... .  |.|. |||  .   | |||.|.||.|.|.      . .||.||||...   . .. ...        . |.. .||||  
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

FH--GHLSEKADVFTFGVVVLE
     . |||.||. ||.|. |
RMNFCQYSEKSDVYSFGIVLWE
Kinase IRAK-0_aj.AA TK 361-560 17 3.1e-36 118.43 In-house 1-386 (486) Show / Hide 
Range on Protein: 361-560
Range on HMM: 1-386/486
Sequence Identity: 17% (68 aa)

FSDDKKLGEGGFG---AVYKG--------------------------TFGDGTEIAIKKLSVSSKQGEQQ--------------FLNEVKVIGSVQ----
    |||||| ||    ||||                          . |  |. |.| |   . . ...              ||.|. ..   .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HRNLVRLLGCCVEG------------SERLLVYEFLKNNS----LEKALL---DDMLSEEETPR-----------------------------------
 | |.|||.|.|..|               ..| |. .. .    | . |    ...  |...|                                    
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LSLTTRYNILLGTARGLTYLHED--SQI--RIVHRDIKPSNILLDETFE-----------AKISDFGLA
                               |.. ..  . .  |.|. |||.   .    ..||||.   |.|..|              .||.||||.
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCE-FIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

R-----LYEEDEATEIITTKVAGTYGY--------------------------MAPEYAFHGH---------LSEKADVFTFGVVVLE
|     |  ...  .  ..|  .. |                           ||||  ....          ..| ||. |||.. |
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWE
Kinase IRAK-0_aj.AA Dicty4 361-557 30 8.7e-36 116.95 In-house 1-206 (277) Show / Hide 
Range on Protein: 361-557
Range on HMM: 1-206/277
Sequence Identity: 30% (63 aa)

FSDDKKLGEGGFGAVYKGTFGDGTEIAIKKL----SVSSKQGEQQFLNEVKVIGSVQHRNLVRLLGCCV----EGSERLLVYEFLKNNSLEKALLD--DM
   ....|.|.|| |||||   |.| |.|||     ...    . |..||.  .. .| |.. ..| |     . .. . | |..   .|.. |.|    
INIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSE

LSEEETPRLSLTTR-YNILLGTARGLTYLHEDSQIRIVHRDIKPSNILLDETFEAKISDFGLARLYEEDEATEIITTKVAGTYGYMAPEYAFHGHLSEKA
  .. .. ..| .|   . . .|||...||. .  .|.|||.|..|.| |. . .|..||||...  ..|     .. ..|| ..||||   |    |||
QQQSIKLDWPLIKRAMRMAFDAARGMNWLHC-CNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKA

DVFTFGVV
||. || |
DVYSFGIV
Kinase IRAK-0_aj.AA MLK 361-557 25 5.8e-35 118.76 In-house 1-225 (291) Show / Hide 
Range on Protein: 361-557
Range on HMM: 1-225/291
Sequence Identity: 25% (60 aa)

FSDDKKLGEGGFGAVYKGTFGDGTE-----IAIKKLS------VSSKQGEQQFLNEVKVIGSVQHRN----LVRLLGCCVE-GSERLLVYEFLKNNSLEK
.   ...|.|.||.|.||..  ...     .|.|.        ...    ..|  |..    ..|.|     ....|.| . ... ..| |.. . ||  
IQFHEWIGSGSFGKVWKGRW-RNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

ALLD-DMLSE---EETP---RLSLTTRYNILLGTARGLTYLHEDSQIRIVHRDIKPSNILLDE------TFEAKISDFGLAR-LYEEDEATEIITTKVAG
 | . .  ..    . .   . ..    |. |  |||. |||.. .  |.|||.|..|||.||         .||.|||..| ... . ..    .. ||
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TN---MMSNAG

TYGYMAPEYAF----HGHLSEKADVFTFGVV
|| .|||| ..    ..  |||.||. .|||
TYAWMAPE-VIQQFRCEKYSEKCDVWSWGVV
Kinase IRAK-0_aj.AA S_TKc 361-640 22 7.2e-34 119.75 SMART 1-231 (231) Show / Hide 
Range on Protein: 361-640
Range on HMM: 1-231/231
Sequence Identity: 22% (66 aa)

FSDDKKLGEGGFGAVYKGTFGD-GTEIAIKKLSVSSKQGEQQFLNEVKVIGSVQHRNLVRLLGCCVEGSERLLVYEFLKN--NSLEKALLDDMLSEEETP
.   .|.|.|.|| |||..  . | . |||...       .....|...  . .| |.|.|...... ..  .| |.. .   .     | |.. .  ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGD-----LFDYIKKRGRH

R----LSLTTRYNILLGTARGLTYLHEDSQIRIVHRDIKPSNILLDETFEAKISDFGLARLYEEDEATEIITTKVAGTYGYMAPEYAFHGHLSE-KADVF
.    ..  .   ..  ....| |.|  |. .|.|||.||.||||||  . ||.||||||..          | . ||  |||||     . .  |.|. 
GLRFPFPE-HARFYMYQICCALEYCH--SH-GIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL---GYGKCKCDWW

TFGVVVLETLAGRKNRDVTLPGPEQYLLEWAWQLHSDGLLANLLDPKLVRSSSNEQERTLVQAIHIALMCTQASPQDRPSMSHVVA---------ML
 .|... | |.|.   .      .| ...                                .|...   | |  |..||.   . .          .
SCGCILYEMLCGYPPFP-----QMQMMFKKIG---------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase IRAK-0_aj.AA TK-Unique 361-560 25 1.2e-32 109.9 In-house 1-231 (294) Show / Hide 
Range on Protein: 361-560
Range on HMM: 1-231/294
Sequence Identity: 25% (61 aa)

FSDDKKLGEGGFGAVYKGTFGDGT-------EIAIKKLS-VSSKQGEQQFLNEVKVIGSVQ-HRNLVRLLGCCVEGS-ERLLVYEFLKNNSLEKALLDDM
.  ....||| || |..|..  ..        .|.|.|   .... .|.||.| ..  ..  | |.|..||||.. .   ....|.. . .|.. .|  .
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQH-YLRTC

LSE-----------------EETPR---LSLTTRYNILLGTARGLTYLHE--DSQIRIVHRDIKPSNILLDETFEAKISDFGLARLYEEDEATEIITTKV
  .                 ...||   .|. . |... . |.|. ||..  .   .|||||.  .|.|| | ...||.|||.||  . ..... .... 
RPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRK---KIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQG

AGTYGYMAPEYAF--HGHL-SEKADVFTFGVVVLE
   . .||||.    ||.  ..| ||  |||.  |
RIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWE
Kinase IRAK-0_aj.AA Dicty4-Unclassified 364-564 32 1.5e-32 108.75 In-house 4-204 (263) Show / Hide 
Range on Protein: 364-564
Range on HMM: 4-204/263
Sequence Identity: 32% (69 aa)

DKKLGEGGFGAVYKGTFGDGTEIAIKKLSVSSKQGE----QQFLNEVKVIGSVQHRNLVRLLGCCVEG----SERLLVYEFL-KNNSLEKALLDDMLSEE
|. .|.| |  |.||    | ..|.||.   . .      | |. || . ||.|| |||.. | |.      |    | ||. | | .|  . .   || 
DQFIGKGHFSKVHKGNW-KGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFE--VIHSKPSEQ

ETPRLSLTT--RYNILLGTARGLTYLHEDSQIRIVHRDIKPSNILLDETFEAKISDFGLARLYEEDEATEIITTKVAGTYGYMAPEYAFHGHLSEKADVF
. | ..|       . .  |.|. .||      ..||||| ||||.|  | .|| |||..|   . . .   || .|||    .||   |     |.||.
QQP-IKLDDTLIIKYAFDIAQGMQHLH---TRNFIHRDIKSSNILMDKHFNIKIADFGISR---VIDFNFNMTT-IAGTPKWESPECLMHESYNQKSDVY

TFGVVVLETLAG
 ....  | . |
SYAMMLYELATG
Kinase IRAK-0_aj.AA Pkinase_Tyr 361-519 30 4.4e-32 109.29 Pfam 1-165 (270) Show / Hide 
Range on Protein: 361-519
Range on HMM: 1-165/270
Sequence Identity: 30% (52 aa)

FSDDKKLGEGGFGAVYKGTFG-----DGTEIAIKKLSVSSKQGE---QQFLNEVKVIGSV-QHRNLVRLLGCCV-EGSE--RLLVYEFLKNNSLEKALLD
 . .|||||| || |||||       .... |.|.|  .. . .   . |..|.|.  .  .| |.|||.|.|. .|     ..| |. .. .| . | .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

DMLSEEETPRLSLTTRYNILLGTARGLTYLHEDSQIRIVHRDIKPSNILLDETFEAKISDFGLARLYEEDE
     |. ..|.. .  .. .  |.|. ||..   ....|||.   |.|..|.. .||.||||||. ..|.
HR---EDKQPLTMKDLLQMCWQIAKGMEYLES---KNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDD
Kinase IRAK-0_aj.AA TyrKc 361-640 24 1.2e-30 109.02 SMART 1-280 (280) Show / Hide 
Range on Protein: 361-640
Range on HMM: 1-280/280
Sequence Identity: 24% (76 aa)

FSDDKKLGEGGFGAVYKGTFGDGTEIAIKKLSVSSKQGEQQFLNEVKVIGSV--QHRNLVRLLGCCVEG-------SERLLVYEFLKNNSLEKALLDDML
 . .|||||| || |||||    .. |.|.|  ..   .. |..| ..  ..  .| |.|||.|.|...          ..| |. .. .| . | .   
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

SEEETPRLSLTTRYNILLGTARGLTYLHEDSQIRIVHRDIKPSNILLDETFEAKISDFGLARLYEED----EATEIITTK---VA---GTYGYMAPEYAF
       |.. .  .. .  |.|  |||.    ...|||.   |.|..| . .|||||||.|  ..|    |... ...|    .     .  ||||  .
K------LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN

HGHLSEKADVFTFGVVVLETLAGRKNRDVTLPGPEQYLLE----WAWQLHSDGLLANLLDPKLVR----SSSNEQERTLVQAIHIALMCTQASPQDRPSM
.|  ..| ||. |||.  | .           | . |  .      .|     . .    |.       |.     .       | ..| .. | |||..
YGKFTTKSDVWSFGVCMWEIFTY---------GQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF----VCCPDEMYQIMKQCWHEDPEDRPTF

SHVVAML
| ..  .
SEIHECF
Kinase IRAK-0_aj.AA STE 361-560 21 1.9e-30 104.79 In-house 1-260 (359) Show / Hide 
Range on Protein: 361-560
Range on HMM: 1-260/359
Sequence Identity: 21% (59 aa)

FSDDKKLGEGGFGAVYKGTFGD----------------GTEIAIKKLSVSSKQG-----------------EQQFLNEVKVIGSVQ--HRNLVRLLGCCV
. . .|.|.|.|| |||.   .                |. .|||........                  .||.|.|.|.    .  | | |. .||..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EG-------SERLLVYEFLKNNSLEKALL-DDMLSEEET------PRLSLTTRYNILLGTARG-LTYLHEDSQIRIVHRDIKPSNILLDETFEAKISDFG
 .       .|  .. |.. . ||.. .    .  .. .       |.. .    |.  . .| | |||.     |.||||||.||||     .|..|||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFG

LARLYEED-------------EATEIITTKVAGTYGYMAPEYAFH------GHLSEKADVFTFGVVVLE
..   ...             | .   .. ..||  .||||          .. ..|.|.  .| ...|
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIE
Kinase IRAK-0_aj.AA LISK 366-560 27 9.8e-30 93.63 In-house 1-231 (296) Show / Hide 
Range on Protein: 366-560
Range on HMM: 1-231/296
Sequence Identity: 27% (64 aa)

KLGEGGFGAVYKGTFG-DGTEIAIKKLS-----VSSKQGEQQFLNEVKVIGSVQHRNLVRLLGCCVE-GSERLLVYEFLKNNSLEKALLDDMLSEEETPR
..|.|.|| |||||   .|...|||...     .  .  .  .| ||... . .|.| |.  | |..  ..  .| |. .   |.  | |  .       
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDK---HKIP

LSLTTRYNILLGTARGLTYLHEDSQIRIVHRDIKPSNILLDET----FEAKISDFGLARLYEEDE---------------------------ATEIITTK
|. . | .| |. |.|..|||.     |.||| |  |.|..|     ...|. |||.||. ....                              . . |
LPWPQRVKIALDIACGMSYLHSMN---IIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQRK

----VAGTYGYMAPEYAFHGHLSEKADVFTFGVVVLE
    . ||   ||||       .|..||| ||.|..|
RRMTICGTPYWMAPEMLLGQSYDESCDVFSFGIVLCE
Kinase IRAK-0_aj.AA TK 608-640 20 1.9e-05 13.38 In-house 453-486 (486) Show / Hide 
Range on Protein: 608-640
Range on HMM: 453-486/486
Sequence Identity: 20% (7 aa)

QERTLVQAIHI-ALMCTQASPQDRPSMSHVVAML
....  .....  ..| .. |.|||..| .. .|
PPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase IRAK-0_aj.AA TK-Unique 622-640 36 0.000609 9.62 In-house 276-294 (294) Show / Hide 
Range on Protein: 622-640
Range on HMM: 276-294/294
Sequence Identity: 36% (7 aa)

CTQASPQDRPSMSHVVAML
|.| .|..||| . .. .|
CWQWEPEERPSFRQIKHRL
Kinase IRAK-0_aj.AA MLK 621-640 35 0.014248 4.9 In-house 272-291 (291) Show / Hide 
Range on Protein: 621-640
Range on HMM: 272-291/291
Sequence Identity: 35% (7 aa)

MCTQASPQDRPSMSHVVAML
.| .. | .|||....|  |
QCWNQDPHKRPSFRQIVQHL
Kinase IRAK-0_aj.AA Pkinase_Tyr 535-557 47 0.015319 9.23 Pfam 181-203 (270) Show / Hide 
Range on Protein: 535-557
Range on HMM: 181-203/270
Sequence Identity: 47% (11 aa)

MAPEYAFHGHLSEKADVFTFGVV
||||  ..|  ..| ||  |||.
MAPECINYGKFTTKSDVWSFGVL
Kinase IRAK-0_aj.AA LISK 618-640 30 0.035735 2.63 In-house 274-296 (296) Show / Hide 
Range on Protein: 618-640
Range on HMM: 274-296/296
Sequence Identity: 30% (7 aa)

IALMCTQASPQDRPSMSHVVAML
....|.   | .||| ...|  |
LCFDCCKYDPKNRPSFKEIVQWL
Kinase IRAK-0_aj.AA Dicty4-Unclassified 622-640 31 0.036447 3.17 In-house 245-263 (263) Show / Hide 
Range on Protein: 622-640
Range on HMM: 245-263/263
Sequence Identity: 31% (6 aa)

CTQASPQDRPSMSHVVAML
|   .|. ||.|  ..  |
CWHNDPNKRPTMNQIIQYL
Kinase IRAK-0_aj.AA Pkinase_Tyr 620-640 33 0.052086 7.43 Pfam 250-270 (270) Show / Hide 
Range on Protein: 620-640
Range on HMM: 250-270/270
Sequence Identity: 33% (7 aa)

LMCTQASPQDRPSMSHVVAML
..| .. |.|||..| .. .|
KQCWHYDPEDRPTFSEIHEQL