Gene IRAK-0_l (S.moellendorffii)

IRAK-0_l

Species: S.moellendorffii
Alias: IRAK-0_l
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAK-0

Sequence

Name Sequence Type Origin Length Description Download
IRAK-0_l.AA Protein None 281 None Fasta, JSON
IRAK-0_l.NA RNA None 846 None Fasta, JSON
IRAK-0_l.kin_dom Protein Kinase Domain None 33 None Fasta, JSON

Protein domain

Protein domains of IRAK-0_l.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Malectin IRAK-0_l.AA Malectin 1-90 37 3.7e-12 49.03 Pfam 100-202 (202) Show / Hide 
Range on Protein: 1-90
Range on HMM: 100-202/202
Sequence Identity: 37% (39 aa)

MRSGSYTVHLHFAEIIIDT---GQDGPG-----VGIQGDRKLKDFNIREEANGSLRALRRSFTVVNVSNGVRD--IHLLGWGKEHVALHSD--LSG-PLI
...|.||| ||||||.. .   . ..||     | ||| . ||||.|..||.|. .|  ..|  |.|.||. .  ||.   || ...        | |.|
LENGNYTVILHFAEIYFQDTDQTWNSPGRRVFDVYIQGKLVLKDFDIWKEAGGKGKAAHKEFINVTVTNGTLEYVIHFYWAGKGTCCIPFRKGYYGNPKI

STI
| |
SAI
Kinase IRAK-0_l.AA AGC 152-183 33 4.1e-11 23.48 In-house 1-39 (395) Show / Hide 
Range on Protein: 152-183
Range on HMM: 1-39/395
Sequence Identity: 33% (13 aa)

FDPLRLLGTGAFGKVYKGVL-------SDGTVVAIKQLN
|. |...|.|.|||||           . | . |.| |.
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLK
Kinase IRAK-0_l.AA Ciliate-A9 152-180 34 7.8e-10 18.71 In-house 1-32 (392) Show / Hide 
Range on Protein: 152-180
Range on HMM: 1-32/392
Sequence Identity: 34% (11 aa)

FDPLRLLGTGAFGKVYKGV-LS--DGTVVAIK
| |   .| ||||.|...  ..  |....|.|
FEPIKIIGEGAFGCVIQCRDIQQEDKQEYAVK
Kinase IRAK-0_l.AA LISK 157-184 51 1.5e-09 26.98 In-house 1-29 (296) Show / Hide 
Range on Protein: 157-184
Range on HMM: 1-29/296
Sequence Identity: 51% (15 aa)

LLGTGAFGKVYKGVLS-DGTVVAIKQLNR
 .| |.||||||| .  .|.|.|||.. |
EIGKGFFGKVYKGTHRQTGQVMAIKMIHR
Kinase IRAK-0_l.AA MST 152-183 42 1.1e-08 23.62 In-house 1-33 (254) Show / Hide 
Range on Protein: 152-183
Range on HMM: 1-33/254
Sequence Identity: 42% (14 aa)

FDPLRLLGTGAFGKVYKGV-LSDGTVVAIKQLN
|| . .|| |..|.||| . ...| .||||...
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVP
Kinase IRAK-0_l.AA TKL 158-184 33 1.2e-08 27.25 In-house 1-36 (364) Show / Hide 
Range on Protein: 158-184
Range on HMM: 1-36/364
Sequence Identity: 33% (12 aa)

LGTGAFGKVYKGVLSD---------GTVVAIKQLNR
.| |.||.||||..           |..||.|....
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKS
Kinase IRAK-0_l.AA RAD53 152-183 30 7.2e-08 18.98 In-house 1-33 (305) Show / Hide 
Range on Protein: 152-183
Range on HMM: 1-33/305
Sequence Identity: 30% (10 aa)

FDPLRLLGTGAFGKVYKGVL-SDGTVVAIKQLN
..  . ||.|.||.|....  ... .||||...
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIID
Kinase IRAK-0_l.AA STE 152-183 29 8.2e-08 23.79 In-house 1-48 (359) Show / Hide 
Range on Protein: 152-183
Range on HMM: 1-48/359
Sequence Identity: 29% (14 aa)

FDPLRLLGTGAFGKVYKGVLSD----------------GTVVAIKQLN
.. .. .| ||||.|||..  .                |...||||.|
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMN
Kinase IRAK-0_l.AA IRAK 152-182 37 1.4e-07 23.11 In-house 1-32 (317) Show / Hide 
Range on Protein: 152-182
Range on HMM: 1-32/317
Sequence Identity: 37% (12 aa)

FDPLRLLGTGAFGKVYKGVLSDGT-VVAIKQL
|.. ...| |.|| ||.|...  | ..|.| |
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKL
Kinase IRAK-0_l.AA TK 152-182 23 2.5e-07 19.79 In-house 1-60 (486) Show / Hide 
Range on Protein: 152-182
Range on HMM: 1-60/486
Sequence Identity: 23% (14 aa)

FDPLRLLGTGAFG---KVYKGVLSDG--------------------------TVVAIKQL
   .. || |.||   .|||| . ..                          | ||.|.|
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKML
Pkinase_Tyr IRAK-0_l.AA Pkinase_Tyr 152-188 33 7.3e-07 23.87 Pfam 1-42 (270) Show / Hide 
Range on Protein: 152-188
Range on HMM: 1-42/270
Sequence Identity: 33% (14 aa)

FDPLRLLGTGAFGKVYKGVLS-----DGTVVAIKQLNRITGD
   .. || ||||.||||..      ... ||.| |.  . .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMH
Kinase IRAK-0_l.AA TK-Unique 152-184 27 5e-06 16.88 In-house 1-40 (294) Show / Hide 
Range on Protein: 152-184
Range on HMM: 1-40/294
Sequence Identity: 27% (11 aa)

FDPLRLLGTGAFGKVYKGVLSDGT-------VVAIKQLNR
.  ....|.|||| |..| .. ..       .||.|.|..
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKD
Kinase IRAK-0_l.AA Pkinase 152-184 32 7e-06 21.9 Pfam 1-34 (293) Show / Hide 
Range on Protein: 152-184
Range on HMM: 1-34/293
Sequence Identity: 32% (11 aa)

FDPLRLLGTGAFGKVYKGVLSDGTV-VAIKQLNR
.  .| .| |.||.|||..  .    ||.|....
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKK
Kinase IRAK-0_l.AA IRAK 195-210 56 0.000697 9.84 In-house 206-221 (317) Show / Hide 
Range on Protein: 195-210
Range on HMM: 206-221/317
Sequence Identity: 56% (9 aa)

DVYSFGVLVLEIVSGR
||||||. .||...|.
DVYSFGIVLLEVLTGC
Kinase IRAK-0_l.AA LISK 194-211 38 0.00102 7.73 In-house 220-237 (296) Show / Hide 
Range on Protein: 194-211
Range on HMM: 220-237/296
Sequence Identity: 38% (7 aa)

ADVYSFGVLVLEIVSGRT
.||.|||....||. ...
CDVFSFGIVLCEIITRVK
Kinase IRAK-0_l.AA TKL 194-211 44 0.002077 8.15 In-house 270-287 (364) Show / Hide 
Range on Protein: 194-211
Range on HMM: 270-287/364
Sequence Identity: 44% (8 aa)

ADVYSFGVLVLEIVSGRT
.||||||..  ||.....
CDVYSFGIVLWEILTRCR
Kinase IRAK-0_l.AA TK-Unique 195-208 64 0.003424 7.0 In-house 221-234 (294) Show / Hide 
Range on Protein: 195-208
Range on HMM: 221-234/294
Sequence Identity: 64% (9 aa)

DVYSFGVLVLEIVS
||.|||||  ||..
DVWSFGVLMWEIFT
Kinase IRAK-0_l.AA TK 195-208 64 0.01419 3.59 In-house 376-389 (486) Show / Hide 
Range on Protein: 195-208
Range on HMM: 376-389/486
Sequence Identity: 64% (9 aa)

DVYSFGVLVLEIVS
||.|||||. ||..
DVWSFGVLMWEIFT
Kinase IRAK-0_l.AA Pkinase_Tyr 195-211 55 0.989027 3.1 Pfam 196-213 (270) Show / Hide 
Range on Protein: 195-211
Range on HMM: 196-213/270
Sequence Identity: 55% (10 aa)

DVYSFGVLVLEIVS-GRT
||.|||||  ||.. |..
DVWSFGVLMWEIFTYGEQ
Pkinase IRAK-0_l.AA Pkinase 193-211 31 1.184657 3.39 Pfam 192-210 (293) Show / Hide 
Range on Protein: 193-211
Range on HMM: 192-210/293
Sequence Identity: 31% (6 aa)

PADVYSFGVLVLEIVSGRT
..|..|.|... | ..||.
KVDMWSCGCILYEMLCGRP