IRAK-Un_bt

Species: S.moellendorffii
Alias: IRAK-Un_bt
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
IRAK-Un_bt.AA Protein None 80 None Fasta, JSON
IRAK-Un_bt.NA RNA None 243 None Fasta, JSON
IRAK-Un_bt.kin_dom Protein Kinase Domain None 58 None Fasta, JSON

Protein domain

Protein domains of IRAK-Un_bt.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase IRAK-Un_bt.AA TKL 1-62 24 5e-15 50.57 In-house 143-247 (364) Show / Hide
Range on Protein: 1-62
Range on HMM: 143-247/364
Sequence Identity: 24% (26 aa)

RGLKYLHEIVS-----PLIIHRDFKSSNILLADKFN--------------TKVSDFGLAKLGLDKA------------------------GLGTQGYVAP
||. |||         | ||||| ||.|||. ....               |..||||..    .                           || .. ||
RGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAP

EYVKN
|  ..
EVLRG

Kinase IRAK-Un_bt.AA Dicty4 1-58 38 2.3e-13 41.08 In-house 123-187 (277) Show / Hide
Range on Protein: 1-58
Range on HMM: 123-187/277
Sequence Identity: 38% (26 aa)

RGLKYLHE-IVSPLIIHRDFKSSNILLADKFNTKVSDFGLAK---LGL---D--KAGLGTQGYVAPE
||. .||. .  | ||||| ||.|.|  . .. ||.||||..    .    |  ..  || ...|||
RGMNWLHCCN--PVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPE

Kinase IRAK-Un_bt.AA AGC 14-58 23 4.5e-12 26.01 In-house 175-277 (395) Show / Hide
Range on Protein: 14-58
Range on HMM: 175-277/395
Sequence Identity: 23% (24 aa)

IIHRD-FKSSNILLADKFNTKVSDFGLAKLGL-----------------------------------------------------DKAG--LG--TQGYV
|||||  |  |||| .. . | .||||.| |                                                      |..    |  |  |.
IIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYM

APE
|||
APE

Kinase IRAK-Un_bt.AA Dicty4-Unclassified 1-40 47 6.4e-12 37.07 In-house 120-156 (263) Show / Hide
Range on Protein: 1-40
Range on HMM: 120-156/263
Sequence Identity: 47% (19 aa)

RGLKYLHEIVSPLIIHRDFKSSNILLADKFNTKVSDFGLA
.|. .||   .  .|||| ||||||.   || |. |||..
QGMQHLH---TRNFIHRDIKSSNILMDKHFNIKIADFGIS

Kinase IRAK-Un_bt.AA Pkinase 1-58 40 7.4e-12 43.0 Pfam 119-181 (293) Show / Hide
Range on Protein: 1-58
Range on HMM: 119-181/293
Sequence Identity: 40% (27 aa)

RGLKYLHEIVSPLIIHRDFKSSNILLADKFNT----KVSDFGLAKL-----GLDKAGLGTQGYVAPE
|||.|.|.     ||||| |..|||. .. ..    |..||||||.     .  .   || .|.|||
RGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDYNNS-MTTFCGTPWYMAPE

Kinase IRAK-Un_bt.AA DRK 1-58 38 7.5e-12 36.46 In-house 109-172 (258) Show / Hide
Range on Protein: 1-58
Range on HMM: 109-172/258
Sequence Identity: 38% (25 aa)

RGLKYLHEIVSPLIIHRDFKSSNILLADKFNTKVSDFGLAK-------LGLDKAGLGTQGYVAPE
.|. |||    | ||||| || | |  . .  ||.||||.         .  .   || . .|||
KGMIYLHC-CNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPE

Kinase IRAK-Un_bt.AA TKL-Unique 1-42 46 8.6e-12 38.03 In-house 121-166 (290) Show / Hide
Range on Protein: 1-42
Range on HMM: 121-166/290
Sequence Identity: 46% (22 aa)

RGLKYLHEIVSPLIIHRDFKSSNILLADK-----FNTKVSDFGLAKL
.|. |||    | ||||| ||||.|.  .     .| |..||||.|.
QGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKF

Kinase IRAK-Un_bt.AA Dicty5 1-58 32 4.7e-11 34.27 In-house 115-173 (260) Show / Hide
Range on Protein: 1-58
Range on HMM: 115-173/260
Sequence Identity: 32% (20 aa)

RGLKYLHEIVSPLIIHRDFKSSNILLADKFNTKVSDFGLAK---LGLDKAG-LGTQGYVAPE
.....|| .    ||||| || |.|.   .  |. |||      . .     .||| . |.|
QSMRHLHSMN---IIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACE

Kinase IRAK-Un_bt.AA CDK10 1-41 58 6.5e-11 33.93 In-house 111-148 (285) Show / Hide
Range on Protein: 1-41
Range on HMM: 111-148/285
Sequence Identity: 58% (24 aa)

RGLKYLHEIVSPLIIHRDFKSSNILLADKFNTKVSDFGLAK
|||||||.     .|||| | ||.|..||   || |||||.
RGLKYLHDN---FMIHRDLKVSNLLMTDKGCIKVADFGLAR

Kinase IRAK-Un_bt.AA MLK 1-41 40 9.6e-11 33.63 In-house 135-181 (291) Show / Hide
Range on Protein: 1-41
Range on HMM: 135-181/291
Sequence Identity: 40% (19 aa)

RGLKYLHEIVSPLIIHRDFKSSNILLAD------KFNTKVSDFGLAK
||. |||.   ..||||| ||.|||...      . . |..|||...
RGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSR

Kinase IRAK-Un_bt.AA Ciliate-C1 14-58 28 1.5e-10 23.07 In-house 150-230 (328) Show / Hide
Range on Protein: 14-58
Range on HMM: 150-230/328
Sequence Identity: 28% (23 aa)

IIHRDFKSSNILLADKFNTKVSDFGLAKL-----------------GLDKA-------------------GLGTQGYVAPE
| ||| |  |||| . || |..|||.|                   .. .                     .|| || |||
ICHRDLKPENILLDENFNLKIADFGFAQFLNSASSQNTLSKQKDGEKMNHNTSSTECSDASSDESHWLYVCMGTEGYMAPE