Gene LmjF28.1760 (L.major)
LmjF28.1760
Species: L.major
Alias: LmajK153, LmjF28.1760
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| LmjF28.1760.AA | Protein | None | 1597 | None | Fasta, JSON |
| LmjF28.1760.kin_dom | Protein Kinase Domain | None | 261 | None | Fasta, JSON |
Protein domains of LmjF28.1760.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | LmjF28.1760.AA | VPS15 | 23-203 | 31 | 7.9e-19 | 61.85 | In-house | 60-247 (296) | Show / Hide |
Range on Protein: 23-203 Range on HMM: 60-247/296 Sequence Identity: 31% (62 aa) NCLWYSLVCEGDGFCVLQRPYVAFTLRERLVARPVWTAQEKLCIVYQLLEAVAHLHETYGLTHGDIKPNNVLVQSTGVLLLSDMALFKPCQMPLDSPLLF ||. |. | | | .. | || .| |. || . || | |.|.|. .| |||||. |.|| |. ..|.| | |||| | | | | NCCPYQKVIETDKAAYMMRQYVKHNLYDRISTRPFLQMIEKKWIAFQTLCALEQCHKQGNVCHGDIKSENILVTSWNWCYLTDFACFKPCYLPEDNPADF DYYYDTDENRACFVAPEKFSDQPLPTPPPESKTRGSATY-------------NVSNVNFDGHTASMDVFSTACVVLFLYKEE-DPL-TLSQVLSLR .. || | | |||.| . . .. . . . | | .|| || ||.. |. | |. ..||... | TFFFDTSRRRTCYIAPERFVS--------NTEQDQDSNNGNMRDIHTDSIDRQQNPWLFGELTPAMDIFSAGCVIAELFCEGDQPPFDYSQLCKYR |
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| Kinase | LmjF28.1760.AA | GSK | 66-105 | 43 | 1.4e-09 | 24.8 | In-house | 121-160 (328) | Show / Hide |
Range on Protein: 66-105 Range on HMM: 121-160/328 Sequence Identity: 43% (18 aa) IVYQLLEAVAHLHETYGLTHGDIKPNNVLVQ-STGVLLLSD ..||.. . |.||. | ||||.|.|| .|||| ..| YMYQMFRGLAYLHSHG-ICHRDIKPQNILVDPDTGVLKICD |
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| Kinase | LmjF28.1760.AA | Ciliate-E1 | 58-110 | 35 | 1.3e-08 | 24.61 | In-house | 106-157 (202) | Show / Hide |
Range on Protein: 58-110 Range on HMM: 106-157/202 Sequence Identity: 35% (19 aa) WTAQEKLCIVYQLLEAVAHLHETYGLTHGDIKPNNVLVQSTGVLLLSDMALFK .| |.|..|..||..... || |...|.|||| |.|. . | ....| .. | FTFQQKMQIIFQLIDGLIELH-QYNIIHRDIKPQNILINNQGNYVYCDFGISK |
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| Kinase | LmjF28.1760.AA | CMGC | 66-105 | 22 | 4.2e-08 | 21.73 | In-house | 185-247 (513) | Show / Hide |
Range on Protein: 66-105 Range on HMM: 185-247/513 Sequence Identity: 22% (14 aa) IVYQLLEAVA--HLHETYG-LTHGDIKPNNVLVQST--------------------GVLLLSD . ||.|.... ..| | | |.|| |.|. .. |.| . | YMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICD |
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| Kinase | LmjF28.1760.AA | Ciliate-C3 | 63-106 | 40 | 4.4e-08 | 25.34 | In-house | 98-140 (140) | Show / Hide |
Range on Protein: 63-106 Range on HMM: 98-140/140 Sequence Identity: 40% (18 aa) KLCIVYQLLEAVAHLHETYGLTHGDIKPNNVLVQSTGVLLLSDM || | |.| |. ||| . . |||||. |.|. | . . . | KLQISKQILQAIDYLHE-HNIVHGDIKFSNILINSKDEIKIIDF |
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| S_TKc | LmjF28.1760.AA | S_TKc | 3-259 | 12 | 6.1e-08 | -60.5 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 3-259
Range on HMM: 1-231/231
Sequence Identity: 12% (39 aa)
DNAGEQL---------RIVDST--------------------LKRTTPRNCLWYSLVCEGDGFCVLQRPYVAF---TLRERLVARPV------WTAQEKL
.... . .. ||. | . |.. .. . |. .|..... |. . .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HAR
CIVYQLLEAVAHLHETYGLTHGDIKPNNVLVQSTGVLLLSD--MALFKPCQMPLDSPLLFDYYYDTDENRAC----FVAPEKFSDQPLPTPPPESKTRGS
...||...|....|. | | |.|| |.|. . .. ..| .| . . | ..||| .
FYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL--------------------TTFCGTPWYMAPEVL-----------------
ATYNVSNVNFDGHTA-SMDVFSTACVVLFLYKEEDPLTLSQVLSLRHLANAEAREAFVAPVLRDANVPAALHPLLLPMLCATAEERPSARELVN---RGL
|.. . |. | |.. .. . | |. . .. | |.. .. .|. |.||.| |. .
-----------GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG----------------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIK
QQRIF
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CHPWF
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| Kinase | LmjF28.1760.AA | CDC2 | 66-106 | 31 | 7.3e-08 | 19.69 | In-house | 108-147 (301) | Show / Hide |
Range on Protein: 66-106 Range on HMM: 108-147/301 Sequence Identity: 31% (13 aa) IVYQLLEAVAHLHETYGLTHGDIKPNNVLVQSTGVLLLSDM . ||.|..|...| . . | |.|| | |. ..|.. ..|. YMYQILQGVHFCH-QRRIMHRDLKPQNILIDKKGNIKIADF |
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| Kinase | LmjF28.1760.AA | Pkinase | 65-105 | 28 | 2.5e-07 | 27.01 | Pfam | 112-155 (293) | Show / Hide |
Range on Protein: 65-105 Range on HMM: 112-155/293 Sequence Identity: 28% (13 aa) CIVYQLLEAVAHLHETYGLTHGDIKPNNVLVQSTGVL----LLSD ...||.|......|. | | |.|| |.|. ..|.. ..| FYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICD |
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| Kinase | LmjF28.1760.AA | Ciliate-B2 | 61-105 | 30 | 4.2e-07 | 12.65 | In-house | 103-147 (197) | Show / Hide |
Range on Protein: 61-105 Range on HMM: 103-147/197 Sequence Identity: 30% (14 aa) QEKLC-IVYQLLEAVAHLHETYGLTHGDIKPNNVLVQSTGVLLLSD ..||. ...||... .. | .| |||| |.|. . | ...| NQKLYQMIFQLIDGLIQFR-MYNILHLDIKPQNILFMQNGNYVYCD |
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| Kinase | LmjF28.1760.AA | CAMK | 66-105 | 19 | 8.6e-07 | 17.15 | In-house | 184-239 (425) | Show / Hide |
Range on Protein: 66-105 Range on HMM: 184-239/425 Sequence Identity: 19% (11 aa) IVYQLLEAVAHLHETYGLTHGDIKPNNVLVQST-----------------GVLLLSD .. |...||...|. | |.|| |.|... . . ..| YFRQICSAVHYCHSHN-IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIID |
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| Kinase | LmjF28.1760.AA | STE7-Unclassified | 66-99 | 47 | 9.3e-07 | 19.95 | In-house | 124-157 (301) | Show / Hide |
Range on Protein: 66-99 Range on HMM: 124-157/301 Sequence Identity: 47% (16 aa) IVYQLLEAVAHLHETYGLTHGDIKPNNVLVQSTG |.||.. . .||| . . | |||| |.|| | | IAYQVIHGLWYLHEKHHIIHRDIKPGNILVNSKG |
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| Kinase | LmjF28.1760.AA | CDKL | 66-105 | 34 | 1e-06 | 18.89 | In-house | 103-142 (286) | Show / Hide |
Range on Protein: 66-105 Range on HMM: 103-142/286 Sequence Identity: 34% (14 aa) IVYQLLEAVAHLHETYGLTHGDIKPNNVLVQ-STGVLLLSD ...|.|.|....| . | |||| | |. . |.. | | YMWQILKAINFCHK-HNCIHRDIKPENILITPKNGQVKLCD |
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| WD40 | LmjF28.1760.AA | WD40 | 1128-1167 | 15 | 0.271487 | 6.34 | Pfam | 1-39 (39) | Show / Hide |
Range on Protein: 1128-1167 Range on HMM: 1-39/39 Sequence Identity: 15% (6 aa) AAALSSVSAHMGAIYAAAPSPSANGIVISAGARGEAFVWQ ... .| ..... | .|. ...|... | .| WKCKHTF-GHTHWVTCCAWHPDMGHYLASGSRDGTIRIWD |
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| WD40 | LmjF28.1760.AA | WD40 | 1186-1241 | 19 | 0.774428 | 5.03 | Pfam | 1-39 (39) | Show / Hide |
Range on Protein: 1186-1241 Range on HMM: 1-39/39 Sequence Identity: 19% (11 aa) RVAAATSKAGVHTYTACQWISVPGQRRDFTLASVPASASCSLVAFASTDGAVRVLD . .| . |. |.| | .....| .| || .|. | WKCKHTF-GHTHWVTCCAWHPD----------------MGHYLASGSRDGTIRIWD |
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| WD40 | LmjF28.1760.AA | WD40 | 1429-1467 | 22 | 0.006316 | 11.04 | Pfam | 1-39 (39) | Show / Hide |
Range on Protein: 1429-1467 Range on HMM: 1-39/39 Sequence Identity: 22% (9 aa) WPAFQCCRNGGGAIRTMLTQPT-HGCVFTGSEDGYIRSWS | . .... . | ....||.|| || |. WKCKHTF-GHTHWVTCCAWHPDMGHYLASGSRDGTIRIWD |
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| WD40 | LmjF28.1760.AA | WD40 | 1561-1591 | 41 | 7.1e-07 | 22.41 | Pfam | 17-39 (39) | Show / Hide |
Range on Protein: 1561-1591 Range on HMM: 17-39/39 Sequence Identity: 41% (13 aa) SWGPSNSGSGGGGEPCYLLSGSRDGTLTLWD .| |. ...||.|||||||. .|| AWHPD--------MGHYLASGSRDGTIRIWD |
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