Gene 84131.m00003 (T.vaginalis)

84131.m00003

Species: T.vaginalis
Alias: 84131.m00003, TvagK0850
External Links:
Annotation:

Classification

Group: Other
Family: Other-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
84131.m00003.AA Protein None 596 None Fasta, JSON
84131.m00003.kin_dom Protein Kinase Domain None 315 None Fasta, JSON

Protein domain

Protein domains of 84131.m00003.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase 84131.m00003.AA Pkinase 184-308 27 8.7e-18 63.97 Pfam 80-213 (293) Show / Hide 
Range on Protein: 184-308
Range on HMM: 80-213/293
Sequence Identity: 27% (39 aa)

PLYRKG----TLTAYIQ--NNPNL--TNLELLEKFYQICLDVRNIHNHHIILRDLKPDNILLDEFDKP----HYADFDVS----VFDTDKAYDFTITRFY
.. ..|     | .||.  .. ..  .  |.   .|||.  .  .|.. || |||||.|||.|. . .    . .|| ..          ...|. |..|
EYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWY

TAPEVEQNLFKSKYVGYGVKSDIFSLGCVLNYMFNHNYPYS
 ||||   .   .. .|| |.|..|.||.| .|.. . |..
MAPEV---IR--GGQYYGPKVDMWSCGCILYEMLCGRPPFP
Kinase 84131.m00003.AA STE 220-313 34 3.8e-15 50.05 In-house 168-274 (359) Show / Hide 
Range on Protein: 220-313
Range on HMM: 168-274/359
Sequence Identity: 34% (39 aa)

IHNHHIILRDLKPDNILLDEFDKPHYADFDVSVFDTD-------------------KAYDFTITRFYTAPEV-EQNLFKSKYVGYGVKSDIFSLGCVLNY
.|.|||| ||.||.||||        .|| |.   ||                   | . |. |  . |||| .||  . .  ||..|.|| ||||..  
LHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-RDKGYDTKCDIWSLGCTIIE

MFNHNYPYSIYTPL
| . ..|.. ..|.
MATGKPPWHDMHPM
Kinase 84131.m00003.AA Ciliate-E2 189-466 13 3e-14 45.31 In-house 119-306 (365) Show / Hide 
Range on Protein: 189-466
Range on HMM: 119-306/365
Sequence Identity: 13% (45 aa)

GTLTAYIQNN-----------PNLTNLELLEKFYQICL---------------DVRNIHNHH-IILRDLKPDNILLDEFDKPHYADFDVSVFDTDK----
|.|  ||.||            ..|  | .. ..||.                 .. .|. . || ||.||.|||.     .  .||  | . .|.    
GDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNR

-------AYDFTI------------------------TRFYTAPEVEQNLFKS---KYVGYGVKSDIFSLGCVLNYMFNHNYPYSIYTPLIPKTVIYLID
        | |                          |  | |||. ..   .   |  ||. |.||.|||..| .|   ..|.                
THKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF----------------

FMRNPNPDSRPTIDELISLTLGTMKYYRSNPVNEGHIGLMNYVPRPDDKINPKQNSDYGENRFKKHADNRKNAHNPENNQNSNKRPPPQNINPSQDSSDS
                                                                                                    
----------------------------------------------------------------------------------------------------

DTEDNSESDNCNLTKSDTKKTTKSDTKKITKSDIKKIIKSNIK
                                 ...|.. .|.
---------------------------------QQQIKQCKID
Kinase 84131.m00003.AA Ciliate-E2b 212-307 34 8.5e-14 38.47 In-house 110-210 (272) Show / Hide 
Range on Protein: 212-307
Range on HMM: 110-210/272
Sequence Identity: 34% (35 aa)

QICLDVRNIHNHHIILRDLKPDNILLDEFDKPHYADFDVSVFDTDKAY----DFTI--TRFYTAPEVEQNLFKSKYVGYGVKSDIFSLGCVLNYMFNHNY
.|||  .  ||  || ||.|| ||..|.   .  .|. .. .  .|.      |||  | .| |||. | | .    ||..|.||.|.| .|  .     
SICLCLEYLHNQNIIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTFTIIGTPHYMAPEIIQSL-QPGGKGYTYKVDIWSVGICLYEFMCGYV

PY
|.
PW
Kinase 84131.m00003.AA AGC 220-297 21 6.9e-13 28.16 In-house 169-295 (395) Show / Hide 
Range on Protein: 220-297
Range on HMM: 169-295/395
Sequence Identity: 21% (30 aa)

IHN-HHIILRD-LKPDNILLDEFDKPHYADFDVSVF-----------------------------------------------------DTDKAYDFTI-
.|. ..|| || |||.||||||    . .||  .                                                       ..|... |   
LHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGP

-TRFYTAPEVEQNLFKSKYVGYGVKSDIFS--LGCVL
 |  | |||.           ||   |. |  |||..
CTPEYMAPEIL----------YGKACDWWSFGLGCLM
S_TKc 84131.m00003.AA S_TKc 121-541 11 1.8e-12 6.09 SMART 1-231 (231) Show / Hide 
Range on Protein: 121-541
Range on HMM: 1-231/231
Sequence Identity: 11% (52 aa)

PRGFKVLGYGAHSVVLHSDEFFSSHIF------KFSKLDLSVENKIKEILGIPIYYPNLAVPNKYFTSSPLYRK--GTLTAYIQNNPN------LTNLEL
 .  ...| || ..|    .  . .|.      .  .  ...  | .    . .|.      ....    .     |.|  ||....       ..  . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HA

LEKFYQICLDVRNIHNHHIILRDLKPDNILLDEFDKPHYADFDVSVFDTDKAYDFTITRFYTAPEVEQNLFKSKYVGYGV-KSDIFSLGCVLNYMFNHNY
   .||||. .  .|.|.|| |||||.||||||      .|| .. .     . |  |..| ||||          |||  |.|. |.||.|  |.    
RFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---------GYGKCKCDWWSCGCILYEMLCGYP

PYSIYTPLIPKTVIYLIDFMRNPNPDSRPTIDELISLTLGTMKYYRSNPVNEGHIGLMNYVPRPDDKINPKQNSDYGENRFKKHADNRKNAHNPENNQNS
|..        ..  ... ..                                                                               
PFP--------QMQMMFKKIG-------------------------------------------------------------------------------

NKRPPPQNINPSQDSSDSDTEDNSESDNCNLTKSDTKKTTKSDTKKITKSDIKKIIKSNIKKIIKSNIKKITKSDTKTSSNNLKRGSNISRKKDPKYPGT
                                                                                                    
----------------------------------------------------------------------------------------------------

FRQKQIFSDSLNELLYLLNMRNSN--ISLPDEEL-------MPMI
       |... ...  .  .. .  ..  .          .| .
-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 84131.m00003.AA Ciliate-E1 190-291 23 2.2e-12 37.0 In-house 82-202 (202) Show / Hide 
Range on Protein: 190-291
Range on HMM: 82-202/202
Sequence Identity: 23% (28 aa)

TLTAYIQ-------------NNPNLTNLELLEKFYQICLDVRNIHNHHIILRDLKPDNILLDEFDKPHYADFDVSVFDTDKAYDFTITRFYTAPEVEQNL
.|. |.|             |. ..| ..... ..|.   .  .|.. || ||.||.||| . ...  |.|| .| |   . .. .  . ||     .. 
SLKDYLQNHNRLEYWQQCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQ

FK------SKYVGYGVKSDIF
 .       |   .. ||||.
YNCPEQEHNKNQKINYKSDIY
Kinase 84131.m00003.AA Ciliate-E2-Unclassified 189-479 13 3.5e-12 38.56 In-house 106-320 (352) Show / Hide 
Range on Protein: 189-479
Range on HMM: 106-320/352
Sequence Identity: 13% (47 aa)

GTLTAYIQNNPN-----------------LTNLELL-----EKFYQICLDVRNIHNHH-IILRDLKPDNILLDEFD---KPHYADFDVS-----------
|.|  ||.....                 .|  . .       |.||..    .|  . || ||.||.|||.|.     ..  .||  |           
GDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDT

-------VFDTDKAYDFTITRFYT----APEVEQNLFKS--KYVGYGVKSDIFSLGCVLNYMFNHNYPYSIYTPLIPKTVIYLIDFMRNPNPDSRPTIDE
       ... .....|. |  |     |||| |.   .  |      |.||.|||..| .|   .||.. ..  . ...|. .    |           
NQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA----YKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWI-N-N-----------

LISLTLGTMKYYRSNPVNEGHIGLMNYVPRPDDKINPKQNSDYGENRFKKHADNRKNAHNPENNQNSNKRPPPQNINPSQDSSDSDTEDNSESDNCNLTK
                                                                                                    
----------------------------------------------------------------------------------------------------

SDTKKTTKSDTKKITKSDIKKIIKSNIKKIIKSNI----KKITKS
         .    ... ....|| .. .. |..     |.. ..
---------A----YRKQLYQNIKQKNIQFPKFPWQQIPKHWSPE
Kinase 84131.m00003.AA C8 217-297 28 7.1e-12 37.6 In-house 136-226 (226) Show / Hide 
Range on Protein: 217-297
Range on HMM: 136-226/226
Sequence Identity: 28% (26 aa)

VRNIHNHHIILRDLKPDNILLDEFDKPH----YADFDVSVFDTDKAYDFTITRF-------YTAPEVEQNLFKSKYVGYGVKSDIFSLGCVL
| .|| . |. ||.||.|.|. .  .       .||... . ..    . .  .       | |||.|.   . .|  |  .||.||.| ||
VNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAYFAPEIEKK-QDNQYKQYRIQSDLFSVGLVL
Kinase 84131.m00003.AA Ciliate-C8 217-297 26 3.1e-11 36.8 In-house 132-238 (238) Show / Hide 
Range on Protein: 217-297
Range on HMM: 132-238/238
Sequence Identity: 26% (28 aa)

VRNIHNHHIILRDLKPDNIL--LDEFDKPH--YAD------FDVSVFDTDKAY-----DFTITRFY-----------TAPEVEQNLFKSKYVGYGVKSDI
| ..| ..|. || ||.|.|  .|. . |    .|      |. . . ..         |  |  |           .|||||..  . ..  .  |||.
VNYLHCFNIMHRDIKPHNFLVCFDQQYQPTIKLCDFKKQCDFGFASQLPKNKSHYHSKKFKGTDQYIEMYFCGNWGYFAPEVEKKQSRIQSDIFSKKSDS

FSLGCVL
.|.| ||
YSVGLVL
Kinase 84131.m00003.AA CAMK 210-297 25 6.1e-11 30.75 In-house 185-324 (425) Show / Hide 
Range on Protein: 210-297
Range on HMM: 185-324/425
Sequence Identity: 25% (35 aa)

FYQICLDVRNIHNHHIILRDLKPDNILLDEFD-----------------KPHYADFDVS--VFD------------------------TDKAYDFTITRF
| |||  |. .|.|.|. |||||.|||||. .                 .   .||  .  ...                        ..| ..|  |  
FRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPE

YTA-PEVEQN-LFKSKY-------VGYGVKSDIFSLGCVL
| | ||| .    ....        .|| |.|. |.|..|
YMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVIL
Kinase 84131.m00003.AA TKL 221-297 22 2.3e-10 33.57 In-house 149-279 (364) Show / Hide 
Range on Protein: 221-297
Range on HMM: 149-279/364
Sequence Identity: 22% (29 aa)

HNHH--------IILRDLKPDNILLDEFDK--------------PHYADFDVSVFDTD----------------------KAYDFTITRFYTAPEV-EQN
|...        || ||||..|||.||  .              .  .||  | | .                       . .    |  . |||| ...
HSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQ

LFKSKYV---------GYGVKSDIFSLGCVL
.. ...|          |  |.|..| | ||
MNYTEKVGIDEFCKGFEYSEKCDVYSFGIVL
TyrKc 84131.m00003.AA TyrKc 125-343 18 0.000107 -146.69 SMART 5-280 (280) Show / Hide 
Range on Protein: 125-343
Range on HMM: 5-280/280
Sequence Identity: 18% (53 aa)

KVLGYGAHSVV-------------LHSDEFFSSHIFKFSKLDLSVENKIKEILG------IPIYYPNLAVP--------NKYFTSSPLYRKGTLTAYIQN
|.|| ||  .|             |..|           . |.  | .|   ||      . .|    ..           ..    .  .| |  |...
KKLGEGAFGEVYKGTWKIQVAVKMLKEDA----------REDFMREARIMCKLGGHHPNIVRLYG--VCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

NPN-LTNLELLEKFYQICLDVRNIHNHHIILRDLKPDNILLDEFDKPHYADFDVSVFDTDK-------AYDFT----ITR-----FYTAPEVEQNLFKSK
. . |.. .||.  .||.   . .| ...| |||   |.|..|      .||  | . .|.        |  .     ..       .|||.       .
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI------N

YVGYGVKSDIFSLGCVL--------NYMFN-----------HNYPYSIYTPLIPKT---------VIYLIDFMR---NPNPDSRPTIDELISLT
|  .  |||..| | ..            .           ..|  . | . .|.             . . |.   . .|..|||  |.... 
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 84131.m00003.AA TKL 312-343 21 0.020375 4.53 In-house 333-364 (364) Show / Hide 
Range on Protein: 312-343
Range on HMM: 333-364/364
Sequence Identity: 21% (7 aa)

PLIPKTVIYLIDFMRNPNPDSRPTIDELISLT
| .|. .. |.    ...|..||. .|...  
PDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL