Gene TVAG_127400 (T.vaginalis)
TVAG_127400
Species: T.vaginalis
Alias: TVAG_127400, TvagK1048
External Links:
Annotation:
Group:
Other
Family:
Other-Unique
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| TVAG_127400.AA | Protein | None | 298 | None | Fasta, JSON |
| TVAG_127400.kin_dom | Protein Kinase Domain | None | 102 | None | Fasta, JSON |
Protein domains of TVAG_127400.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| S_TKc | TVAG_127400.AA | S_TKc | 6-287 | 18 | 7.6e-09 | -47.17 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 6-287
Range on HMM: 1-231/231
Sequence Identity: 18% (58 aa)
EILEPPIGGGFEGKVYLTKSGK-----VVKIMADVPENFKSAYRQFLLTDFFEKCYTNPPFAHIFELSTSNGKIKLKMEKYYK---DLSARMKT------
. .|| | ||||. . | .||. ....| . .. . .|. ... . || || ..|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK--HHPNIVKLYDVFQD----DHLYMVMEYCDGDLGDLFDYIKKRGRHGL
---ITRDDAYKFMDQIFSGISMLIDLEYVFQDLKPGNILCNIHGSIFLTDFGSGVFLTEIDGKRQFTFMTNKIYTDPELSKGWFDV-MNYVYSLGVIFLE
.. .| ..| ||.... . .. . |||| |||.. | ..|||. .| || | ||. .. ..|.|.|. |
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYE
MLHHGKI--KEKSLEYIKQLQKGEEEKPASHESNDKSQSQSNNNNEETAYDEMLTETIEHFKKNPYAIEFNDISDEEKEFITFCIS-DFEGRYTFEEAQN
|| |. . .|.. |.| |.|| | | | |.| || .
MLC-GYPPFP-QMQMMFKKIG----------------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQ
--------EFK
..
DEWDIKCHPWF
|
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| Kinase | TVAG_127400.AA | GEK | 108-141 | 47 | 3e-06 | 16.36 | In-house | 113-146 (269) | Show / Hide |
Range on Protein: 108-141 Range on HMM: 113-146/269 Sequence Identity: 47% (16 aa) ISMLIDLEYVFQDLKPGNILCNIHGSIFLTDFGS | . |.|| |.|| |.| .| | | |||| IDSVHQLHYVHRDIKPDNVLLDMNGHIRLADFGS |
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| Kinase | TVAG_127400.AA | MEK5 | 104-188 | 33 | 4e-06 | 18.17 | In-house | 102-184 (254) | Show / Hide |
Range on Protein: 104-188 Range on HMM: 102-184/254 Sequence Identity: 33% (29 aa) IFSGISMLIDLEYVFQDLKPGNILCNIHGSIFLTDFGSGVFLTEIDGKRQFTFMTNKIYTDPE-LSKGWFDVMNYVYSLGVIFLEM | |. | .| . | || |.| | .| | | ||| | . . |.. | || .| . . |.|||. |.|| IVKGLNYLWNLKIMHRDVKPSNMLVNTQGQIKLCDFGVSTQLVNSITR---TYIGTNAYMAPERISGDQYGIHSDVWSLGIFFMEM |
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| Kinase | TVAG_127400.AA | Ciliate-A2 | 77-140 | 30 | 5e-06 | 17.33 | In-house | 76-148 (272) | Show / Hide |
Range on Protein: 77-140 Range on HMM: 76-148/272 Sequence Identity: 30% (22 aa) KMEKY-YKDLSARMK-----T--ITRDDAYKFMDQIFSGISMLIDLEYVFQDLKPGNILCNIHGS-IFLTDFG .|||. ...|. . . | . ...| || ..| | .||. ||...||| . .. | | ||| QMEKCPECSLQDWIDKFQNQQKFIPDHQFVHFACQILDAIEYLHNKNYVLRDLSLRNILIDQDNQIIKLCDFG |
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| Kinase | TVAG_127400.AA | PLK1 | 84-167 | 33 | 5e-06 | 15.43 | In-house | 88-170 (253) | Show / Hide |
Range on Protein: 84-167 Range on HMM: 88-170/253 Sequence Identity: 33% (28 aa) DLSARMKTITRDDAYKFMDQIFSGISMLIDLEYVFQDLKPGNILCNIHGSIFLTDFGSGVFLTEIDGKRQFTFMTNKIYTDPEL .| | |.|| .. .| || |. | ... . ||| ||. | | . . ||| .. | || |. | | ||. ELHKRRKAITEPECRYYMYQIVEGCQYLHNNKIIHRDLKLGNLFLNDHLQVKIGDFGLATKC-EYDGERKKTLCGTPNYIAPEV |
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| Kinase | TVAG_127400.AA | AMPK | 92-140 | 34 | 5e-06 | 13.83 | In-house | 97-145 (254) | Show / Hide |
Range on Protein: 92-140 Range on HMM: 97-145/254 Sequence Identity: 34% (17 aa) ITRDDAYKFMDQIFSGISMLIDLEYVFQDLKPGNILCNIHGSIFLTDFG .. ..| .|. || ||.. . .. | |||| |.| ... .| . ||| LQEREACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFG |
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| Kinase | TVAG_127400.AA | RSK-Unclassified | 90-140 | 29 | 1.3e-05 | 13.07 | In-house | 96-146 (283) | Show / Hide |
Range on Protein: 90-140 Range on HMM: 96-146/283 Sequence Identity: 29% (15 aa) KTITRDDAYKFMDQIFSGISMLIDLEYVFQDLKPGNILCNIHGSIFLTDFG | .. ||. .. . | .. .. |||| ||. | . ||||. KCFCEDDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFD |
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| Kinase | TVAG_127400.AA | SGK | 117-140 | 54 | 1.3e-05 | 12.83 | In-house | 147-170 (283) | Show / Hide |
Range on Protein: 117-140 Range on HMM: 147-170/283 Sequence Identity: 54% (13 aa) VFQDLKPGNILCNIHGSIFLTDFG .. |||| ||| | . ||||| IYRDLKPENILLDHQGHCCLTDFG |
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| Kinase | TVAG_127400.AA | Ciliate-E1 | 103-166 | 29 | 1.5e-05 | 14.53 | In-house | 117-180 (202) | Show / Hide |
Range on Protein: 103-166 Range on HMM: 117-180/202 Sequence Identity: 29% (19 aa) QIFSGISMLIDLEYVFQDLKPGNILCNIHGSIFLTDFGSGVFLTEIDGKRQFTFMTNKIYTDPE |.. |...| .. ..|.|| ||| | | ..||| . || . . . . . . | || QLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPE |
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| Kinase | TVAG_127400.AA | STE7-Unclassified | 120-140 | 57 | 3.2e-05 | 14.46 | In-house | 145-165 (301) | Show / Hide |
Range on Protein: 120-140 Range on HMM: 145-165/301 Sequence Identity: 57% (12 aa) DLKPGNILCNIHGSIFLTDFG |.||||||.| | . ..||| DIKPGNILVNSKGQVKICDFG |
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| Kinase | TVAG_127400.AA | CDK7 | 120-140 | 52 | 4.4e-05 | 9.02 | In-house | 127-147 (288) | Show / Hide |
Range on Protein: 120-140 Range on HMM: 127-147/288 Sequence Identity: 52% (11 aa) DLKPGNILCNIHGSIFLTDFG |||| | | |. | . ..||| DLKPNNLLMNENGQLKIADFG |
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