Gene 92757.m00243 (T.vaginalis)
92757.m00243
Species: T.vaginalis
Alias: 92757.m00243, TvagK1020
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| 92757.m00243.AA | Protein | None | 2338 | None | Fasta, JSON |
| 92757.m00243.kin_dom | Protein Kinase Domain | None | 221 | None | Fasta, JSON |
Protein domains of 92757.m00243.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 92757.m00243.AA | Ciliate-E1 | 23-178 | 21 | 5.1e-10 | 29.26 | In-house | 24-202 (202) | Show / Hide |
Range on Protein: 23-178 Range on HMM: 24-202/202 Sequence Identity: 21% (39 aa) IKLIDTNFE-NDERRQQLFSLVDVYNQIKFAC-LPEIIIKFDPKANQIHTLTRYYHHGSLQNLID-----------ANQIDQLTLEEKMEIIFSVTAATH .|.| ..| |.. |.. . . ..|. | . .|| .. . |.|... ... ||.. .. .. |.| ..||.||| . QKIINCCFNYNQNHFQDEIKEYYKIMKFKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQCQQNQNQFTFQQKMQIIFQLIDGLI ALHANNIIHSNIKPTNILFDHSNTPILCDINFIAQLNTENTIQSGVSMHDDILSLQKIYK------ILL----KNSEVY .||..||||..|||.|||..... ..||. .|. ... |. .. . . .. . |. . ..|..| ELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKSDIY |
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| Kinase | 92757.m00243.AA | NAK | 71-138 | 32 | 1.6e-08 | 24.52 | In-house | 92-169 (299) | Show / Hide |
Range on Protein: 71-138 Range on HMM: 92-169/299 Sequence Identity: 32% (25 aa) LTRYYHHGSLQNLIDANQ-IDQ--LTLEEKMEIIFSVTAATHALHANN----IIHSNIKPTNILFD---HSNTPILCD | |. ||||..|... . .. .| .| |. |. . |.|. . ||| ||..|||.. |.....||| LMEYCCHGSLWDLMNKRLMDKGTCFTEDEILQIFCDVCEGVQAMHQCQPPKPIIHRDIKIENILLSESHHDGNYKLCD |
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| Kinase | 92757.m00243.AA | TKL | 66-138 | 20 | 2.8e-07 | 22.25 | In-house | 111-197 (364) | Show / Hide |
Range on Protein: 66-138 Range on HMM: 111-197/364 Sequence Identity: 20% (20 aa) NQIHTLTRYYHHGS-LQNLIDANQIDQLTLEEKMEIIFSVTAATHALHANN--------IIHSNIKPTNILFDHSNT--------------PILCD .|.. . |...|| | .|. .. .. .. .. . . ||..| ||| ..|. ||| | .| . .|| GQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICD |
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| Kinase | 92757.m00243.AA | Ciliate-B2 | 111-138 | 42 | 3.2e-07 | 12.93 | In-house | 120-147 (197) | Show / Hide |
Range on Protein: 111-138 Range on HMM: 120-147/197 Sequence Identity: 42% (12 aa) LHANNIIHSNIKPTNILFDHSNTPILCD .. .||.| |||.|||| .. ..|| FRMYNILHLDIKPQNILFMQNGNYVYCD |
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| Kinase | 92757.m00243.AA | Ciliate-B1 | 74-135 | 30 | 9.6e-07 | 19.77 | In-house | 98-158 (290) | Show / Hide |
Range on Protein: 74-135 Range on HMM: 98-158/290 Sequence Identity: 30% (19 aa) YYHHGSLQNLIDANQIDQLTLEEKMEIIFSVTAATHALHANNIIHSNIKPTNILFDHSNTPI |. |.| |.| |.....|.... ... . . . .||...|.| .|| |||. | || YCEQGDLYNYI-YNCHQNFTHDIVLDFCIQIAKGIQYLHKHKICHRDLKPENILIHKKNVPI |
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| S_TKc | 92757.m00243.AA | S_TKc | 8-211 | 13 | 2e-06 | -81.61 | SMART | 14-231 (231) | Show / Hide |
Range on Protein: 8-211 Range on HMM: 14-231/231 Sequence Identity: 13% (33 aa) KVGVIKDLKTNYFYVIKLIDTNFENDERRQQLFSLVDVYNQIKFACLPEIIIKFDPKANQIHTLTRYYHH--GSLQNLIDANQI----DQLTLEEKMEII || .. ||. . || |. ... . ... . . . .. |. . .. . | . |.| .|. .. ... . .. KVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYM FSVTAATHALHANNIIHSNIKPTNILFDHSNTPILCD-----------------------INF-----------IAQLNTENTIQSGVSMHDDILSLQKI . | .| ..||| .|| |||.|. . .|| .. .. . . . . .|.. YQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQLTTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLCGYPPFP---------QMQMM YKILLKNSEVYKTISVNNFIESCCNEE----ITTFQILE--NMIQNNFFM .|... . .. .||. |.. . .| ..|. | . .. FKKIG-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | 92757.m00243.AA | TKL-Sp1 | 92-138 | 37 | 2e-06 | 15.77 | In-house | 95-142 (263) | Show / Hide |
Range on Protein: 92-138 Range on HMM: 95-142/263 Sequence Identity: 37% (18 aa) LTLEEKMEIIFSVTAATHALHANNIIHSNIKPTNILFDH-SNTPILCD |. . ||.| | | .|| || | ||| |.. . . | .|| LDWAKKMQISCEVLQAVTFMHACNILHLDIKPANVMVERATRRPYICD |
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| Kinase | 92757.m00243.AA | Ciliate-E3 | 110-132 | 65 | 2e-06 | 16.47 | In-house | 118-140 (202) | Show / Hide |
Range on Protein: 110-132 Range on HMM: 118-140/202 Sequence Identity: 65% (15 aa) ALHANNIIHSNIKPTNILFDHSN |.|. ||||| ||| ||| | .| AIHEKNIIHSDIKPDNILVDKNN |
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| Kinase | 92757.m00243.AA | SAMK | 116-138 | 50 | 3e-06 | 15.89 | In-house | 126-149 (295) | Show / Hide |
Range on Protein: 116-138 Range on HMM: 126-149/295 Sequence Identity: 50% (12 aa) IIHSNIKPTNILFD-HSNTPILCD ||| .|. |||.| .. ||| | IIHRDINCDNILLDNENDEPILID |
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| Kinase | 92757.m00243.AA | Ciliate-A1 | 78-127 | 33 | 6e-06 | 16.29 | In-house | 86-133 (301) | Show / Hide |
Range on Protein: 78-127 Range on HMM: 86-133/301 Sequence Identity: 33% (17 aa) GSLQNLIDANQ-IDQLTLEEKMEIIFSVTAATHALHANNIIHSNIKPTNIL | |.|.. | . || .|| . ..| ||.|. .|| ||| GNLFNYCYQNDYMKK---EEIYEICYQIIEGYADIHDHNILHRDLKPQNIL |
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| Kinase | 92757.m00243.AA | Ciliate-E2 | 74-138 | 25 | 8e-06 | 15.96 | In-house | 115-199 (365) | Show / Hide |
Range on Protein: 74-138 Range on HMM: 115-199/365 Sequence Identity: 25% (23 aa) YYHHGSLQNLIDAN----------QIDQLTLEEKMEIIFSVTA---------------ATHALHANN-IIHSNIKPTNILFDHSNTPILCD |. .|.|. .| | . ..|..| .|. .. | . || .| ||| .||| |||| . ..| YCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIID |
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| Sel1 | 92757.m00243.AA | Sel1 | 285-320 | 27 | 0.000123 | 18.53 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 285-320 Range on HMM: 1-43/43 Sequence Identity: 27% (12 aa) PFSAFNLA--KIYLSGS----VEKLN-IEK-SFDLLKYASNQGL | ...||. .|. | |.. . .|| .| ... | .|| P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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| Sel1 | 92757.m00243.AA | Sel1 | 608-643 | 29 | 2.2e-08 | 30.94 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 608-643 Range on HMM: 1-43/43 Sequence Identity: 29% (13 aa) VNAMFLFA--NICKDGI--G-VEN-D-YKL-ACQYYKKAADIGH . |.. . . .|. | |. | |.. | ..|.|||. || P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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| Sel1 | 92757.m00243.AA | Sel1 | 392-427 | 27 | 2.7e-08 | 30.67 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 392-427 Range on HMM: 1-43/43 Sequence Identity: 27% (12 aa) IDAMFRYG--TMLREGH--G-IAQ-N-LQE-AAQIFQDAAERGD |....| |. .| | . | . ... |.. .| |||.|. P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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| Sel1 | 92757.m00243.AA | Sel1 | 356-391 | 25 | 3.1e-08 | 30.48 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 356-391 Range on HMM: 1-43/43 Sequence Identity: 25% (11 aa) PEANFILS--QIYEKGI--S-VEK-N-SEM-AMKYLRLSANQGN | | . | ..|..|. |.. . | |.......|.||. P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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| Sel1 | 92757.m00243.AA | Sel1 | 428-463 | 27 | 4.8e-08 | 29.84 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 428-463 Range on HMM: 1-43/43 Sequence Identity: 27% (12 aa) VQAKNKFG--LFLRNGI--G-VKR-D-YIK-AASLFKQAADQNY . | .. | ... .|. | |.. | | | |. ....||.|.. P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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| Sel1 | 92757.m00243.AA | Sel1 | 536-571 | 20 | 1.1e-07 | 28.71 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 536-571 Range on HMM: 1-43/43 Sequence Identity: 20% (9 aa) KYGQNNYG--LALLFGY--G-IKK-N-EKL-AVQYFHDSAKQGD .|.|.| .....|. | ... . .. |..... .|.||. P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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| Sel1 | 92757.m00243.AA | Sel1 | 464-499 | 31 | 3.9e-07 | 26.84 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 464-499 Range on HMM: 1-43/43 Sequence Identity: 31% (14 aa) AEAQNNYG--VMIKLGE--G-VPK-N-SKI-SAKFVEKAANQGC . ||.|.| | |. | ||. . . .... .|||.|| P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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| Sel1 | 92757.m00243.AA | Sel1 | 572-607 | 20 | 1.5e-05 | 21.55 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 572-607 Range on HMM: 1-43/43 Sequence Identity: 20% (9 aa) KYGCLNYG--LCLYEGI--G-CLQ-N-EIE-GMKYIRKSADLGV ...|.| ...|.|. | . | . . .... .|.|..| P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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| Sel1 | 92757.m00243.AA | Sel1 | 500-535 | 27 | 0.00018 | 17.98 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 500-535 Range on HMM: 1-43/43 Sequence Identity: 27% (12 aa) PAAQNNYG--WMLKVGY--G-VEK-S-LPK-SSLFFKLSSEGGS | ||.|.| |. |. | |.. . | . ..... | |. P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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| Sel1 | 92757.m00243.AA | Sel1 | 732-742 | 27 | 10.739197 | 2.13 | Pfam | 33-43 (43) | Show / Hide |
Range on Protein: 732-742 Range on HMM: 33-43/43 Sequence Identity: 27% (3 aa) KYIKEAADKGN .. . ||..|. YWYQKAAEQGH |
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| Sel1 | 92757.m00243.AA | Sel1 | 762-771 | 40 | 1.31324 | 5.16 | Pfam | 34-43 (43) | Show / Hide |
Range on Protein: 762-771 Range on HMM: 34-43/43 Sequence Identity: 40% (4 aa) YLEKAAKNGN ...|||..|. WYQKAAEQGH |
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| Kinase | 92757.m00243.AA | Ciliate-E2 | 826-834 | 33 | 0.211304 | 0.55 | In-house | 357-365 (365) | Show / Hide |
Range on Protein: 826-834 Range on HMM: 357-365/365 Sequence Identity: 33% (3 aa) DDAKNHQFF ....||..| EQILNHPWF |
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| Sel1 | 92757.m00243.AA | Sel1 | 865-900 | 36 | 2e-06 | 24.33 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 865-900 Range on HMM: 1-43/43 Sequence Identity: 36% (16 aa) PEANYQLG--LLYKKGE--K-VEK-D-EQK-ADEEFKKAADKGH | | |.|| ..| .|. |.. | .| | . ..|||..|| P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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| Sel1 | 92757.m00243.AA | Sel1 | 916-932 | 33 | 0.010438 | 12.13 | Pfam | 26-43 (43) | Show / Hide |
Range on Protein: 916-932 Range on HMM: 26-43/43 Sequence Identity: 33% (6 aa) NESE-AEKYFLKAAENGN . . | ... ||||.|. DYEKEAFYWYQKAAEQGH |
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| Sel1 | 92757.m00243.AA | Sel1 | 966-1001 | 15 | 0.0033 | 13.79 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 966-1001 Range on HMM: 1-43/43 Sequence Identity: 15% (7 aa) AELYYRYA--VILRDGI--G-IQI-D-LQK-SSHYFLLAAKMEY . .|... .. .|. | . | ..| . ... .||.. . P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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| Sel1 | 92757.m00243.AA | Sel1 | 1039-1069 | 17 | 1.806807 | 4.7 | Pfam | 1-38 (43) | Show / Hide |
Range on Protein: 1039-1069 Range on HMM: 1-38/43 Sequence Identity: 17% (7 aa) DFSVYLLG--LCLLTGI--G-FTK-D-KSH-AISLLNQS . | || .....|. | .. | . |. .. .. P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKA |
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| Sel1 | 92757.m00243.AA | Sel1 | 1170-1205 | 31 | 8.2e-09 | 32.39 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 1170-1205 Range on HMM: 1-43/43 Sequence Identity: 31% (14 aa) PDAQFYIA--KELEKGD--K-IEQ-D-LEK-AAEYYGEAAENDH | ||.... ...|. ..| | .|| |...| |||..| P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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| Sel1 | 92757.m00243.AA | Sel1 | 1134-1169 | 22 | 2e-07 | 27.81 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 1134-1169 Range on HMM: 1-43/43 Sequence Identity: 22% (10 aa) PQSQFEYG--TCLFEGR--G-IEQ-N-IRQ-GKNLIEKAAVAGN | .|...| ....|. | ..| . ... . . .||| .|. P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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| Sel1 | 92757.m00243.AA | Sel1 | 1206-1241 | 17 | 0.003952 | 13.53 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 1206-1241 Range on HMM: 1-43/43 Sequence Identity: 17% (8 aa) SGALCRLAMIN---INE----TAP-NSDKSQ-GYEMLKAAAEAGN . | ..|.|. . . . . |. . ... .. |||.|. P-AQYNLGMYYMYYHGQFGGCVPQDD-DYEKEAFYWYQKAAEQGH |
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| Sel1 | 92757.m00243.AA | Sel1 | 1898-1932 | 20 | 45.075489 | 0.06 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 1898-1932 Range on HMM: 1-43/43 Sequence Identity: 20% (9 aa) KYALYLLGTCST--EENQ--P-D---K-YEE-AMKNLEKSSKSQN | | || . .. | ||. |.. ..|. . . P-AQYNLG-MYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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| Sel1 | 92757.m00243.AA | Sel1 | 2043-2078 | 31 | 3.9e-10 | 36.79 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 2043-2078 Range on HMM: 1-43/43 Sequence Identity: 31% (14 aa) AKAAFNLG--LLYLKGQ--G-VTK-S-NEN-AAVYFKIAADKGD . |..||| ..|..|| | |.. | |. ... ||..|. P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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| Sel1 | 92757.m00243.AA | Sel1 | 2214-2249 | 22 | 3.1e-09 | 33.78 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 2214-2249 Range on HMM: 1-43/43 Sequence Identity: 22% (10 aa) VNAMCVLG--RMLKQGE--G-TTK-N-PTL-AAKYFLFAAKHGN . |.. || .|. .|. | ... . . . |.... ||..|. P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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| Sel1 | 92757.m00243.AA | Sel1 | 2079-2114 | 27 | 4.2e-09 | 33.37 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 2079-2114 Range on HMM: 1-43/43 Sequence Identity: 27% (12 aa) SASQANYG--LMLKNGY--G-VHK-D-IER-AQKYFELSAKQND . .| |.| .|. .|. | | . | .|. | ......|.|.. P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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| Sel1 | 92757.m00243.AA | Sel1 | 1971-2006 | 27 | 2.9e-08 | 30.56 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 1971-2006 Range on HMM: 1-43/43 Sequence Identity: 27% (12 aa) ASAMYVYA--LMLRSGF--G-VKQ-D-LPL-SVTWFKAAGKRGH . |.| .. .|. | | |.| | . . .. |.. | ..|| P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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| Sel1 | 92757.m00243.AA | Sel1 | 2286-2321 | 20 | 2.3e-07 | 27.56 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 2286-2321 Range on HMM: 1-43/43 Sequence Identity: 20% (9 aa) AEAQCYYA--TMLSNGK-N--IEK-N-REM-AINYFKLAAQQDF . ||.... |. .|. . ... . | |. ....||.|. P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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| Sel1 | 92757.m00243.AA | Sel1 | 2250-2285 | 25 | 9.7e-07 | 25.51 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 2250-2285 Range on HMM: 1-43/43 Sequence Identity: 25% (11 aa) NIAMLNYG--LMLKDGT--G-VDQ-N-IEE-SVKFIKMSADSGN |..|.| .|. .| | | | . .|. .... ...|. |. P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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| Sel1 | 92757.m00243.AA | Sel1 | 2178-2213 | 27 | 2e-06 | 24.29 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 2178-2213 Range on HMM: 1-43/43 Sequence Identity: 27% (12 aa) SDSQLKLG--MMLRSGD--V-LPQ-D-LIT-ALHYIVLSAKQGN . .|..|| .|. |. || | . |... ..|.||. P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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| Sel1 | 92757.m00243.AA | Sel1 | 2007-2042 | 29 | 4e-06 | 23.52 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 2007-2042 Range on HMM: 1-43/43 Sequence Identity: 29% (13 aa) AGGNYNAG--LMIRHGI--G-HPS-N-PSH-AAYYYKQAADAKY . . || | .| ||. | | . . |.|.|..||.. . P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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| Sel1 | 92757.m00243.AA | Sel1 | 2147-2177 | 20 | 0.00337 | 13.76 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 2147-2177 Range on HMM: 1-43/43 Sequence Identity: 20% (9 aa) IKAMYNYG--L---SRI-N--D---D-PME-SARYFQMSAEKGN |.||.| . . . | . . .....|..||.|. P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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| Sel1 | 92757.m00243.AA | Sel1 | 2115-2146 | 20 | 0.049026 | 9.9 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 2115-2146 Range on HMM: 1-43/43 Sequence Identity: 20% (9 aa) PVGLNNLGLVLM--EKG-----DKE-N-----ATLLFKKSADLGN | . .||| .. ..| .. . | ...|.|..|. P-AQYNLG-MYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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