Gene 90149.m00261 (T.vaginalis)
90149.m00261
Species: T.vaginalis
Alias: TvagK0832, 90149.m00261
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| 90149.m00261.AA | Protein | None | 1155 | None | Fasta, JSON |
| 90149.m00261.kin_dom | Protein Kinase Domain | None | 250 | None | Fasta, JSON |
Protein domains of 90149.m00261.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| S_TKc | 90149.m00261.AA | S_TKc | 9-270 | 16 | 6.4e-10 | -31.4 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 9-270 Range on HMM: 1-231/231 Sequence Identity: 16% (47 aa) YDNIQPLFTVGYWDIKRAVQKSTKQHVCLWVFDYPKIKAKERNTNDRHNYMENVIASIKAQQKVRHPNILKIFEVSEDMKSLAFSSEPIEF-------QS |. .... .. .... |.|...| . . . |... |. .| .|||| |...| .| ..| . | .. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYI ANDPC------FTRDEAIFASKQLASAMQFLNEDCHTAYLTLSPEAIFFDKQFNLKLCLFTFAKPYKEISQPIQMRAPWTNNTMHIPARYAAPEVIHNQT . .. |. .| | .|...|.... . . . | || |..|. ..|.| | .|. . .|. | ||||. KKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL---------------TTFCGTPWYMAPEVL---G ITV-RADSFMYGLIVYYFFTNKHALSAISLETHRPSELQSKFDDIPEEYADLIKLCFNDVASLRPNFIAINN-------DEAF . ..| | |.| ... . . .. . ..| |.|. |.. . || . . .. | YGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | 90149.m00261.AA | Ciliate-E2 | 44-270 | 14 | 1.3e-07 | 22.17 | In-house | 48-365 (365) | Show / Hide |
Range on Protein: 44-270
Range on HMM: 48-365/365
Sequence Identity: 14% (46 aa)
KIKAKERNTNDRHNYMENVIASIK-------------AQQKVRHPNILKIFEVSE--DMKSLAFSSEPIEFQSAND----------------PCFTRDEA
||.|.... .. ......| .. .... ||||.|..|. . | ... . | .. .. | .|| |.
KIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEI
IFASKQLAS---------------AMQFLNEDCHTAYLTLSPEAIFFDKQFNLKLCLFTFAK----PYKEISQPIQMRAPWTNNT--MHIPAR-------
.. .||... |...| . . . . || |.| .|.. | ..| ....... |.. ... ... .
KYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQ
------------YAAPEVIHNQT---------ITVRADSFMYGLIVYYFFTNKHALSAISLETHRPSELQSK---------------FDDIPEEYADLIK
| |||.. .. . .| . | | |.. ..|. . . ..... ......| ||||
QNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIK
L----CFNDVASLRPN-FIAINNDEAF
... . |.. . | | . |
KFGKRMLQKDPEKRITGWEQILNHPWF
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| Kinase | 90149.m00261.AA | SCY1 | 118-270 | 17 | 2.3e-07 | 21.63 | In-house | 132-337 (337) | Show / Hide |
Range on Protein: 118-270 Range on HMM: 132-337/337 Sequence Identity: 17% (37 aa) QLASAMQFLNEDCHTAYLTLSPEAIFFDKQFNLKLCL---------FTFAKPYKEIS--QPIQMRAPW-------------TNN---TMHIPARYAAPEV |. .|..||..|||.. . ..||.|| .| |. ..| . . | .| .|. ... . . |||. QILDALSFLHNDCHMVHNNICPESIFVNKNGDWKIGGDDDDAGGWGMDFVCDIQNGNPQMPWFPCQEWREMDYISVSSTKPDNKYPPPCQPNPDWLAPEY IHN-------------QTITVRADSFMYGLIVYYFFTNKH----ALSAISLETHRP------SELQSKFDDIPEEYADL----IKLCFNDVASLRPNFIA ||. |. | .| |. |. .. ...| ..| . ..| . . ... |.||.|. .. .. .. . .||... IHEDQHTPASYNWGQEQKCTWASDMFSLGCLIWWVYNGKKPQITCNSNP-YSTFHRYMEQWNAMSHCWWDHIPKELQEHLGHCYCHLLHQDPTCRPDPQQ INNDEAF . .. | FLQHCYF |
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| Kinase | 90149.m00261.AA | TKL-Unique | 183-264 | 21 | 2e-06 | 19.01 | In-house | 190-286 (290) | Show / Hide |
Range on Protein: 183-264 Range on HMM: 190-286/290 Sequence Identity: 21% (21 aa) ARYAAPEVIHN--QTITVRADSFMYGLIVYYFFTNKH---------ALSAI---SLETHRPSELQSKF-DDIPEEYADLIKLCFNDVASLRPNFIAI .|..||||. . ... .| . .| ... .|.| ... . .... . ... . ...|.|| |||. |... | ||.|. | FRWMAPEVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEI |
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| Kinase | 90149.m00261.AA | SCY1 | 21-97 | 26 | 2.9e-05 | 14.3 | In-house | 1-77 (337) | Show / Hide |
Range on Protein: 21-97 Range on HMM: 1-77/337 Sequence Identity: 26% (21 aa) WDIKRAVQKSTKQHVCLWVFDYPKIKAKERNTNDRHNYMENVIASIKAQQKVRHPNILKIFEVSEDMKS-LAFSSEPI | | ... |.|.| . ..||| | . .... . | . ...| ...||||||..... | | ... .|.| WKIHNGTKKYTGQECSVFVFDKKNIEKWHKDSWWE-EICEFLKKQAKRLKRLRHPNILQYIHPLEESKDCMMYATEEI |
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| Kinase | 90149.m00261.AA | TKL | 116-261 | 11 | 0.000104 | 12.9 | In-house | 138-357 (364) | Show / Hide |
Range on Protein: 116-261 Range on HMM: 138-357/364 Sequence Identity: 11% (26 aa) SKQLASAMQFLNEDCH-------TAYLTLSPEAIFFDKQFN--------------LKLCLFTFAKPYKEISQPIQMRAPWT-----------NNTMHIPA ... |..|..| . .. | .. |. |. .. .|.| | ... .. .. . ..| ALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTP RYAAPEVIHNQ----------------TITVRADSFMYGLIVYYFFTNKHALS-----------------AISLETHRPSELQ---------SKFDDIPE |. ||||. .| . . ..| . .|.. . .| .. . .. . .. .. .. .|.|. RWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPP EYADLIKLCFNDVASLRPNF ....|.. | . .. ||.| SMKKLMQDCWDHDPEKRPSF |
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| Kinase | 90149.m00261.AA | CAMKL | 66-86 | 37 | 0.000373 | 8.99 | In-house | 63-86 (297) | Show / Hide |
Range on Protein: 66-86 Range on HMM: 63-86/297 Sequence Identity: 37% (9 aa) IKAQQKVR---HPNILKIFEVSED |. ..... |||| |..|| |. IQIMKMLNIGKHPNIIKLYEVIET |
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| Kinase | 90149.m00261.AA | Ciliate-E2-Unclassified | 46-270 | 14 | 0.000438 | 10.09 | In-house | 17-352 (352) | Show / Hide |
Range on Protein: 46-270
Range on HMM: 17-352/352
Sequence Identity: 14% (50 aa)
KAKERNTN---------DRHNYMENVI-------ASIKAQQKVR-------------------HPNILKIFEVSEDMKSLAFSSEPI------EFQSAND
|....... . ..|. . | ..|. .. ||.|.| |.. .| . . . | . .. . .
KCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRK
P----------------CFTRDEAI-----FASKQLASAMQFLNEDCHTAYLTLSPEAIFFDKQ---FNLKLCLFTFAKPYKE-----------ISQPIQ
.|| .|. | .|. .. ..| . . . . || |.||.. ...|.. | ..| |.. .....|
KQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQ
MRAPWTNNTMH-IPARYAAPEVIHNQTIT----VRADSFMYGLIVYYFFTNKHALSAISLETHR-----------PSELQSKF----------------D
... . | .| .|.||||. .| .| . | | |.. .... .. . | |. ..|.... .
QMMWTFCGTPNYMP-QYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPK
DIPEEYADLIK----LCFNDVASLRPNFIAINNDEAF
....|..|.|. ... . |..| | | |
HWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
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| TyrKc | 90149.m00261.AA | TyrKc | 9-270 | 13 | 0.000439 | -156.6 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 9-270 Range on HMM: 1-280/280 Sequence Identity: 13% (43 aa) YDNIQPLFT-------VGYWDIKRAVQKSTKQHVCLWVFDYPKIKAKERNTNDRHNYMENVIASIKAQQKV--RHPNILKIFEVSEDM-------KSLAF .. | | |. |. | . .| . .. |. .||||.... | . . | ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----------------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMI SSEPIEF-------QSANDPCFTRDEAIFASKQLASAMQFLNEDCHTAYLTLSPEAIFF------------DKQFNLKLCLFTFAKPYKEI-----SQPI | . .. . .. .. . . | |. |..| . . .... | . | .. .. |. VMEYMPHGDLKDYLRKHRPK-LCMKDLLSFCWQIACGMEYLHSK-------------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDY QMRAPWTNNTMHIPARYAAPEVIHNQTITVRADSFMYGLIVYYFFTN----KHA-----LSAISLETHRPSE-LQSKFDD--------IPEEYADLIKLC . . . . .| | |||.| . | | ...| . ||. .|.. . . . . .. |.| ...| | YRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQC FNDVASLRPNFIAINNDEAF . .. ||.| .| | | WHEDPEDRPTFSEI--HECF |
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| Kinase | 90149.m00261.AA | Ciliate-E6 | 137-159 | 39 | 0.000806 | 8.45 | In-house | 79-101 (154) | Show / Hide |
Range on Protein: 137-159 Range on HMM: 79-101/154 Sequence Identity: 39% (9 aa) LSPEAIFFDKQFNLKLCLFTFAK .... || ||..|.|.| | | . ITLKNIFLDKNMNIKICDFGFQQ |
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