Gene 89034.m00127 (T.vaginalis)

89034.m00127

Species: T.vaginalis
Alias: TvagK0782, 89034.m00127
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
89034.m00127.AA Protein None 400 None Fasta, JSON
89034.m00127.kin_dom Protein Kinase Domain None 236 None Fasta, JSON

Protein domain

Protein domains of 89034.m00127.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 89034.m00127.AA Ciliate-E2-Unclassified 85-208 20 8.9e-18 58.25 In-house 100-272 (352) Show / Hide 
Range on Protein: 85-208
Range on HMM: 100-272/352
Sequence Identity: 20% (36 aa)

MDYIPGNTLTAFMA--------GGYVGMRIKK--RYTLEILA-----GITFQ----LSIMKHKH-IKHRDLKPDNIIIDADM---IPHLIDWDDAT----
|.|..|..|  ..         |.  ....|.  . | .  .      .. |    |. . ||. | |||.||.||..| ..    . .||.  .     
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

---------DRFSLSRSKNH----GTVPFT----APEVFLS-ERR----CESDIFSFGSIMYSIITEAFPFSQ
          ...  ....     ||  .     ||||. . .       ..||.|.| |.| ...  .||..
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYD
Kinase 89034.m00127.AA Ciliate-E2 83-206 18 5e-15 48.0 In-house 111-296 (365) Show / Hide 
Range on Protein: 83-206
Range on HMM: 111-296/365
Sequence Identity: 18% (35 aa)

ILMDYIPGNTLTAFM-------------AGGYVGMRIKKRYTLEILAGITFQ-----------LSIMKHKH-IKHRDLKPDNIIIDADMIPHLIDWDDAT
. |.|. |..|  ..             . .|  ..  |... .|| |.  .           |  .. |. | |||.||.||..     . .||.  ..
LVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSK

DRFSLSRSKNH---------------------------------GTVPFTAPEVFLSERR----------CESDIFSFGSIMYSIITEAFPF
.    .  . |                                 || .. |||.. ..             ..||.|.| |.|  ..  .||
KYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF
Kinase 89034.m00127.AA CAMK 132-206 18 5.3e-12 34.24 In-house 202-334 (425) Show / Hide 
Range on Protein: 132-206
Range on HMM: 202-334/425
Sequence Identity: 18% (25 aa)

HRDLKPDNIIIDADM-----------------IPHLIDWDDATDRFSLSRSK-------------------------NHGTVPFTA-PEVFLSE------
||||||.|| .| ..                    .||.  |.  .. . ..                           || .. | |||....      
HRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQ

---------RRCESDIFSFGSIMYSIITEAFPF
            ..|. | | |.|   .  .||
NATDEEKPYYGPKCDMWSCGVILYIMLCGYPPF
S_TKc 89034.m00127.AA S_TKc 10-325 15 3.1e-11 -12.13 SMART 1-231 (231) Show / Hide 
Range on Protein: 10-325
Range on HMM: 1-231/231
Sequence Identity: 15% (51 aa)

DEKADKIWKSSRGGNGSCYIIKLGD--KLRILKKLFNRSGRRIDDLFDNALKFQIPLSPMFFDNSQNHPGEISNWILMDYIPG--NTLTAFMAGGY----
 |. .||    .|. |..|  .  .  ..  .|..     ..|    .   | . |    ..|  |.     . .. |.|..|   .|  ..        
YEILRKI---GKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK-HHPNIVKLYDVFQD----DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---VGMRIKKRYTLEILAGITFQLSIMKHKHIKHRDLKPDNIIIDADMIPHLIDWDDATDRFSLSRSKNHGTVPFTAPEVFLSERRC-ESDIFSFGSIMY
         ..|. .|. .. .    .  ..| ||||||.|| .|      ..|   |.       .   ||  . ||||.     . ..|. |.| |.|
RFPFPE-HARFYMYQICCALEY----CHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILY

SIITEAFPFSQAYTTRKGLSVLLSQRPEFDRPDLEETLAMLDDFEMMSQSERADSWNIIVTQVEPILVELIKLGIRDDSIFYNEQFMSDPFNNKIARLIR
  ..   ||.   .  . . ...                                                                          .||
EMLCGYPPFP---QMQMMFKKIG--------------------------------------------------------------------SPEAKDFIR

LCWKQDYQERIDPDELQD-EIDKIAKEIL
 |.. | ..|.   |.   | |  . . .
KCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase 89034.m00127.AA Pkinase 82-209 25 2.4e-09 34.1 Pfam 76-215 (293) Show / Hide 
Range on Protein: 82-209
Range on HMM: 76-215/293
Sequence Identity: 25% (37 aa)

WILMDYIPGN----TLTAFMA---GGYV--GMRIKKRYTLEILAGITFQLSIMKHKHIKHRDLKPDNIIIDADMIP----HLIDWDDAT---DRFSLSRS
.. |.| .|      | ...    .| .   ..  |.| ..|| |. .  |      | ||||||.|| || .. .    ...|.  |       .   .
YMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSM----GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MT

KNHGTVPFTAPEVFL--SERRCESDIFSFGSIMYSIITEAFPFSQA
   || .. |||| .  ..   ..|..|.| |.|  ..  .||...
TFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGH
Kinase 89034.m00127.AA TKL 132-225 19 1.9e-08 26.54 In-house 163-318 (364) Show / Hide 
Range on Protein: 132-225
Range on HMM: 163-318/364
Sequence Identity: 19% (30 aa)

HRDLKPDNIIIDADMI-------PHLIDWDDATDRFSLSRSKN----------------------------HGTVPFTAPEVFLSERR------------
|||||..|| .| ..        .. .||.     | |||...                             ||  . ||||.  .              
HRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCK

-----CESDIFSFGSIMYSIITEAFPFS-QAYTTRK---------GLSVLLSQRPE
       .|..||| ... |.|   |.. . | ...          . .. ..||.
GFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPP
Kinase 89034.m00127.AA NZAK 83-143 32 2.4e-07 20.2 In-house 79-139 (329) Show / Hide 
Range on Protein: 83-143
Range on HMM: 79-139/329
Sequence Identity: 32% (20 aa)

ILMDYIPGNTLTAFMAGGYVGMRIKKRYTLEILAGITFQLSIMKHKHIKHRDLKPDNIIID
| | .. |  || |..      |.|      ..| |.  .| .  .|| |||.|. |.| |
IYMEWMEGGNLTQFLMNDKKQLRFKEHRIIKMIADIAETMSYLHKHHIIHRDIKSNNVILD
Kinase 89034.m00127.AA MLK 132-207 26 3e-06 17.94 In-house 150-237 (291) Show / Hide 
Range on Protein: 132-207
Range on HMM: 150-237/291
Sequence Identity: 26% (23 aa)

HRDLKPDNIIIDA------DMIPHLIDWDDATDRFSL-S-RSKNHGTVPFTAPEVF--LSERRCE--SDIFSFGSIMYSIITEAFPFS
|||||. || ||.      ...    | . ..|  .  . . .| ||. . ||||.  . . ..   .|..|.| ... ..|   |..
HRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYK
Kinase 89034.m00127.AA C8 122-196 28 4e-06 17.31 In-house 136-226 (226) Show / Hide 
Range on Protein: 122-196
Range on HMM: 136-226/226
Sequence Identity: 28% (26 aa)

LSIMKHKHIKHRDLKPDNIIIDADMIPH----LIDWDDA---TDRFSLSRSKNH---GTVPFTAPEVFLS------ERRCESDIFSFGSIM
.. .. | | |||.||.|. . .|        | | . |   ..  |   ||..   ||  . |||.         . | .||.|| | ..
VNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAYFAPEIEKKQDNQYKQYRIQSDLFSVGLVL
Kinase 89034.m00127.AA CAMKL 169-206 33 0.000105 10.78 In-house 195-236 (297) Show / Hide 
Range on Protein: 169-206
Range on HMM: 195-236/297
Sequence Identity: 33% (14 aa)

GTVPFTAPEVFLS--ERRC--ESDIFSFGSIMYSIITEAFPF
|. |. |||.|..  .. .  . || | | |.| ... ..||
GSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPF
Kinase 89034.m00127.AA MARK 128-146 57 0.000124 11.26 In-house 123-141 (262) Show / Hide 
Range on Protein: 128-146
Range on HMM: 123-141/262
Sequence Identity: 57% (11 aa)

KHIKHRDLKPDNIIIDADM
|.| |||.||.|| ||...
KNIVHRDIKPENILIDENG
Kinase 89034.m00127.AA RIPK 132-146 60 0.000575 9.37 In-house 132-146 (290) Show / Hide 
Range on Protein: 132-146
Range on HMM: 132-146/290
Sequence Identity: 60% (9 aa)

HRDLKPDNIIIDADM
|||||| || .|...
HRDLKPENILVDNNF
Kinase 89034.m00127.AA RIPK 158-207 25 0.001385 8.05 In-house 167-229 (290) Show / Hide 
Range on Protein: 158-207
Range on HMM: 167-229/290
Sequence Identity: 25% (16 aa)

DRF-----SLSRSKNH-GTVPFTAPEVFL---SER----RCESDIFSFGSIMYSIITEAFPFS
||      . ..|||  ||  . .|| |.   . .      ..|. ||. .|. . |   |..
DRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNKKPIKVVTPKYDVYSFAIVMWEVLTQKHPYE
Kinase 89034.m00127.AA MARK 169-206 40 0.004093 6.22 In-house 167-206 (262) Show / Hide 
Range on Protein: 169-206
Range on HMM: 167-206/262
Sequence Identity: 40% (16 aa)

GTVPFTAPEVFLSERRC--ESDIFSFGSIMYSIITEAFPF
|| |. |||.||... .  . || | | ..| ...  |||
GTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPF
Kinase 89034.m00127.AA CAMKL 128-152 40 0.007521 4.76 In-house 146-172 (297) Show / Hide 
Range on Protein: 128-152
Range on HMM: 146-172/297
Sequence Identity: 40% (11 aa)

KHIKHRDLKPDNIIIDADM--IPHLID
..| |||.||.|| .| ..     .||
HGIVHRDIKPENILLDENGNNNIKIID