Gene Ack (Fruit Fly)

Ack

Species: Fruit Fly
Alias: dACK, CG14992, Ack, SFO085, ACK, DACK, ACK2, BcDNA:GH10777
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 64A6--7,

Classification

Group: TK
Family: Ack

Sequence

Name Sequence Type Origin Length Description Download
Ack.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 261 Kinase domain by global Sugen HMM Fasta, JSON
Ack.AA Protein Various 1096 None Fasta, JSON

Protein domain

Protein domains of Ack.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SAM_Ack Ack.AA SAM_Ack 36-100 53 1.3e-38 134.56 In-house 1-65 (65) Show / Hide 
Range on Protein: 36-100
Range on HMM: 1-65/65
Sequence Identity: 53% (35 aa)

SETAWLEDLLREVQLEQFLDRIRDDLQVTRLAHFDYVLPDDLERCGLGKPAIRRLMEAVRKKKAH
.|..||...|||.||||....|||.|.||||.||||| ..|||..|...|..|||.||..|...|
EECQWLYEFLREAQLEQYYNQIRDHLKVTRLDHFDYVKDEDLECIGMSRPEQRRLWEAYKKMCPH
Sam7 Ack.AA sam7 36-98 17 2.4e-10 34.66 In-house 1-70 (70) Show / Hide 
Range on Protein: 36-98
Range on HMM: 1-70/70
Sequence Identity: 17% (12 aa)

SETAWLEDLLREVQL---EQFLDRIRDDLQ---VTRLAHFDYVLPDDLERCGLGKPA-IRRLMEAVRKKK
  . .. . |.....   .|. |..|| .    || ..|....  .||...|  .|   ......... .
WTFEDVCEWLEWIGMENFQQYCDNFRDHGIDDWVTDGDHLCHMTEEDLMEMGITRPGHRKKIWNHIQQMR
Kinase Ack.AA Ack 146-406 63 5.5e-201 673.98 In-house 1-266 (266) Show / Hide 
Range on Protein: 146-406
Range on HMM: 1-266/266
Sequence Identity: 63% (169 aa)

ITMGLKLGDGSFGVVRRGEWSASPAGKVIPVAVKVLKSDNLTQPGIIDDFFREVQAMHALDHANLVRLYGVVLSQPM-MMITELAERGSLLDTLRKQCR-
||.. |||||.||||.||||.. |.||.|.||||.|.||...||...|||.|||..||.|||..|||||||||.||| ||.||||..|||||.|||.|| 
ITLCEKLGDGCFGVVWRGEWTN-PGGKHIQVAVKCLRSDKMQQPNCMDDFLREVAIMHSLDHPHLVRLYGVVLDQPMLMMVTELAPCGSLLDCLRKHCRT

-HTSLTIIWNWSVQIVTGMAYLEQKRFLHRDLACRNVLLAAG-NKIKIGDFGLMRALPQEDDCYVMSEHK--KVPFPWCAPESLRFRQFSHASDTWMFGV
 ............||..||.|||.||..|||||.||.||... .|.||.||||||||.|..|.|.|..|.  ||||.|||||.||.||||||||.|||||
AFFLIHTLCDFCMQIAMGMRYLEMKRCIHRDLAARNILLFSDDRKVKICDFGLMRALGQNEDYYRMEFHRNLKVPFAWCAPECLRHRQFSHASDVWMFGV

TLWEMFSFGEDPWVGLNGSQILRKIDREGERLHQPDACPPDVYAMMLQCWDKTPAERPTFAALKEYL
|||||||.||.||.|.||.|||.|||.|||||..||.||.|.|.||.|||...||.||||.|....|
TLWEMFSYGEEPWAGCNGYQILQKIDKEGERLPRPDCCPEDIYQMMMQCWQHHPADRPTFSAIRDQL
Kinase Ack.AA Pkinase_Tyr 146-406 39 6.6e-120 406.73 Pfam 1-270 (270) Show / Hide 
Range on Protein: 146-406
Range on HMM: 1-270/270
Sequence Identity: 39% (108 aa)

ITMGLKLGDGSFGVVRRGEWSASPAGKVIPVAVKVLKSDNLTQPG-IIDDFFREVQAMHAL-DHANLVRLYGVVL--SQP--MMMITELAERGSLLDTLR
||.| ||| |.||.|..|.|  .| .. ||||||.|  .. ...  ...||.||.. |. | .| |.||||||..  ..|  .....|... |.||| ||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

KQ---CRHTSLTIIWNWSVQIVTGMAYLEQKRFLHRDLACRNVLLAAGNKIKIGDFGLMRALPQEDDCY-VMSEHKKVPFPWCAPESLRFRQFSHASDTW
|.    .. ..  . ....||  ||.|||.|.. |||||.||.|.. .|..||.||||.|.. ..|| | ..... |.| .|.|||..... |...|| |
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVW

MFGVTLWEMFSFGEDP-WVGLNGSQILRKIDREGERLHQPDACPPDVYAMMLQCWDKTPAERPTFAALKEYL
.|||..||.|..|| | . |.  ......|...|.|. .|. ||...| .|.|||.. |..||||... | |
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase Ack.AA TyrKc 146-406 35 6.5e-113 382.34 SMART 1-280 (280) Show / Hide 
Range on Protein: 146-406
Range on HMM: 1-280/280
Sequence Identity: 35% (104 aa)

ITMGLKLGDGSFGVVRRGEWSASPAGKVIPVAVKVLKSDNLTQPGIIDDFFREVQAMHAL--DHANLVRLYGVVLS--------QPMMMITELAERGSLL
||.| ||| | ||.|..|.|.       |.||||.||.|       . || || . |. |  .| |.||||||...        .|.|...|... |.|.
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLK

DTLRKQCRHTSLTIIWNWSVQIVTGMAYLEQKRFLHRDLACRNVLLAAGNKIKIGDFGLMRALPQE------DDCYVMSE--HKK--VPFPWCAPESLRF
| |||  .. ..    ....||  ||.||..|.. |||||.||.|..... .||.||||.|..  .      .| |...|  ..|  .|  |.|||....
DYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINY

RQFSHASDTWMFGVTLWEMFSFGEDPWVG-----LNGSQILRKIDREGERLHQPDA--------CPPDVYAMMLQCWDKTPAERPTFAALKEYL
. |...|| |.|||..||.|..|. |. |     .. ....... ..|.|. ||.         ||...| .|.|||.  |..||||....|..
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYV-KQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase Ack.AA TK 146-406 22 2.3e-104 350.87 In-house 1-486 (486) Show / Hide 
Range on Protein: 146-406
Range on HMM: 1-486/486
Sequence Identity: 22% (108 aa)

ITMGLKLGDGSFG---VVRRGEWSASP---------------------AGKVIPVAVKVLKSDNLTQPGIIDD--------------FFREVQAMH--AL
||.| ||| | ||   .|..|||   .                      |...|||||.||... ...    |              . .| . |.  ..
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

DHANLVRLYGVVLSQ-------------PMMMITELAERGS----LLDTLRKQCRH--------------------------------------------
.| |.||||||.. .             |.|...|... |.    |.| |||  ..                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------TSLTIIWNWSVQIVTGMAYLEQK------RFLHRDLACRNVLLAAGNK-----------IKIGDFG---
                                ..     ...||  ||.||..|      .| |||||.||.|.. .|.           .||.|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LMRALPQEDDCYVMSEHK-----------------------KVPFPWCAPESLR---------FRQFSHASDTWMFGVTLWEMFSFGEDPWVG-L
     | |.....|| |..|...                       |.|. |.|||.|.         .. |...|| |.|||..||.|..|. |. | .
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

NG---------SQILRKIDRE-----------GERLHQP--DACPP-------------DVYAM-MLQCWDKTPAERPTFAALKEYL
.           ...... |.           |.|. .|  . ||.             ..|.  |.|||.. |..||||..|.|.|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase Ack.AA Syk 146-400 38 7e-86 291.62 In-house 1-257 (257) Show / Hide 
Range on Protein: 146-400
Range on HMM: 1-257/257
Sequence Identity: 38% (99 aa)

ITMGLKLGDGSFGVVRRGEWSAS---PAGKVIPVAVKVLKSDNLTQPGIIDDFFREVQAMHALDHANLVRLYGVVLSQPMMMITELAERGSLLDTLRKQC
.  .  .| | || |. |   .      ...|.||.|.|| .  .||.  . | || | |. |||   ||. |. .  .|||. |.|| |.... | .  
LVQDNEIGCGNFGSVHKGWYMMKSGAGEKQWIKVAIKMLK-ADHNQPADKQEFMREAQVMCQLDHPCIVRMIGICHAEMMMMVMEMAELGPMHKYLQQHR

RHTSL-TIIWNWSVQIVTGMAYLEQKRFLHRDLACRNVLLAAGNKIKIGDFGLMRALPQEDDCYVMSEHKKVPFPWCAPESLRFRQFSHASDTWMFGVTL
 . .   ..  |  |.  || ||| | | ||||| ||||| .    || |||. .||   .. |.   | | |  | |||.  .. |||.|| | ||||.
HEITANNVLELWHTQVAMGMCYLEEKHFVHRDLAARNVLLVNRHYAKISDFGMSKALGADSQYYQATTHGKWPVKWYAPECIYYYKFSHKSDVWSFGVTM

WEMFSFGEDPWVGLNGSQILRKIDREGERLHQPDACPPDVYAMMLQCWDKTPAERPTFA
||||| |  |  .  |. ..  |.  |.|. .|. ||...|. | .||   .  |||| 
WEMFSYGQKPYGEMKGQEVMKFIE-NGHRMNCPNGCPQEMYQLMNKCWIYKWCDRPTFV
Kinase Ack.AA Src 146-406 38 1.6e-85 290.43 In-house 1-255 (255) Show / Hide 
Range on Protein: 146-406
Range on HMM: 1-255/255
Sequence Identity: 38% (103 aa)

ITMGLKLGDGSFGVVRRGEWSASPAGKVIPVAVKVLKSDNLTQPGIIDDFFREVQAMHALDHANLVRLYGVVLSQ-PMMMITELAERGSLLDTLR--KQC
|..  |||.| || |  | |  .     ..||||.||.... .    ..| .| |.|  |.| .||.|| |.    |   .||. ..||||| |.  ...
IKLCRKLGQGQFGEVWMGYWNGN-----TKVAVKTLKPGTMSP----EAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEG

RHTSLTIIWNWSVQIVTGMAYLEQKRFLHRDLACRNVLLAAGNKIKIGDFGLMRALPQEDDCYVMSEHKKVPFPWCAPESLRFRQFSHASDTWMFGVTLW
|| .|..    . |.  ||||||.... ||||| ||||   .|  |..|||| | . ..|| |....  |.|  | ||| .....|.  || | ||. |.
RHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLT

EMFSFGEDPWVGLNGSQILRKIDREGERLHQPDACPPDVYA-MMLQCWDKTPAERPTFAALKEYL
|....|  |  | .  . |....| | |. .|. ||. .|   |||||.|.| .||||. | ..|
EIVTYGRVPYPGMTNHEVLQQVER-GYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase Ack.AA SFK-Src 146-410 39 6.1e-81 239.49 In-house 1-259 (259) Show / Hide 
Range on Protein: 146-410
Range on HMM: 1-259/259
Sequence Identity: 39% (105 aa)

ITMGLKLGDGSFGVVRRGEWSASPAGKVIPVAVKVLKSDNLTQPGIIDDFFREVQAMHALDHANLVRLYGV-VLSQPMMMITELAERGSLLDTLRK-QCR
| .  ||| | || | .| |  . .     |||| ||.    .    . | .| | |  | | ||..|| |     |.  ||||   ||||| |.  . |
IRLEKKLGSGQFGDVWKGRWNNTTE-----VAVKTLKPGAMSA----EEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGR

HTSLTIIWNWSVQIVTGMAYLEQKRFLHRDLACRNVLLAAGNKIKIGDFGLMRALPQEDDCYVMSEHKKVPFPWCAPESLRFRQFSHASDTWMFGVTLWE
   .        |.  |||||| . | ||||| ||||    | .|.||||. | | |.|  |   |  | |  | |||     .||  || | ||. . |
SLRMPQLVDMAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMME

MFSFGEDPWVGLNGSQILRKIDR-EGERLHQPDACPPDVYAMMLQCWDKTPAERPTFAALKEYLASMS
.  .|  |. |.    .|...|| ||.|.  |  ||.  |..|..|| ..| .||||  ||  .    
IVTYGRIPYPGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTFESLKWQMEDFF
Kinase Ack.AA UTK 146-406 30 1.5e-79 270.57 In-house 1-296 (296) Show / Hide 
Range on Protein: 146-406
Range on HMM: 1-296/296
Sequence Identity: 30% (91 aa)

ITMGLKLGDGSFGVVRRGEW-SASPAGKVIPVAVKVLKSDNLTQPGII--DDFFREVQ---AMHALD-HANLVRLYGVVLS-QPMMMITELAERGSLLDT
.  | .|| | ||.|.....  .|. ...  |||||....  .|       || .| .    | ... | |..||.||... .|.|..||..|.|.|.. 
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LRKQCRHTS-------LTIIWNWSVQIVTGMAYLEQKRFLHRDLACRNVLLAAG-------NKIKIGDFG---LMRALP--------QEDDCYVMSEHKK
||.. . .        |.    ....|  ||.||....| |||||.||.|...        ...||.|||   . |...        .|.. | ... ..
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

VPFPWCAPESLRFR-QFSHASDTWMFGVTLWEMFSFGEDPWVGLNGSQILRKIDREG-ERLHQPDACPPDVYAMMLQCWDKTPAERPTFAALKEYL
.|. |.|||.|  . .|...|| | |||..||....|  |. |..  |..  . . |  |. .|..|| .|| .|..|| ..|.|||.|  | . .
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase Ack.AA EGFR 146-407 39 9e-79 261.15 In-house 1-258 (258) Show / Hide 
Range on Protein: 146-407
Range on HMM: 1-258/258
Sequence Identity: 39% (103 aa)

ITMGLKLGDGSFGVVRRGEWSASPAGKV-IPVAVKVLKSDNLTQPGIIDDFFREVQAMHALDHANLVRLYGVVLSQPMMMITELAERGSLLDTLRKQCRH
.  . .|| | || | .| |    . .| ||||.|||.  . | |   ... .|  .|  .||..|||| || ... |...| .   |.||| .|.   .
LKKVKVLGSGAFGTVYKGIWIPE-GENVKIPVAIKVLR--EQTGPKANEEMLDEAYVMASVDHPHLVRLLGVCMHSQMQLVTQYMPYGCLLDYVRQHKDN

TSLTIIWNWSVQIVTGMAYLEQKRFLHRDLACRNVLLAAGNKIKIGDFGLMRALPQEDDCYVMSEHKKVPFPWCAPESLRFRQFSHASDTWMFGVTLWEM
       ||.|||  || |||..|  ||||| ||||.   |..|| |||| . |..... | ...  |.|  | | |....| . |.|| | .|||.||.
IGSQHLLNWCVQIAKGMQYLEEHRMVHRDLAARNVLVKSPNHVKITDFGLAKLLEHDEKEYHAQGG-KMPIKWMALECIHHRCYTHQSDVWSYGVTCWEL

FSFGEDPWVGLNGSQILRKIDREGERLHQPDACPPDVYAMMLQCWDKTPAERPTFAALKEYLA
  ||. |. |.  ..|   ... |||| ||. |  ||| .|..||   .. ||||  | | . 
MTFGQKPYDGIPAREIPDLLEK-GERLPQPPICTIDVYMVMVKCWMIDEDMRPTFKELYEEFK
Kinase Ack.AA SRM 147-407 39 4.1e-77 257.46 In-house 2-253 (253) Show / Hide 
Range on Protein: 147-407
Range on HMM: 2-253/253
Sequence Identity: 39% (103 aa)

TMGLKLGDGSFGVVRRGEWSASPAGKVIPVAVKVLKSDN-LTQPGIIDDFFREVQAMHALDHANLVRLYGVV-LSQPMMMITELAERGSLLDTLRK-QCR
|.. |||.| || |  | |  .     ..||.|| |.|| . |     ..  |.|||  | |  ..||. |. .  |   ||||  .|.|.  ||    .
TLCRKLGEGYFGEVWEGLWKGQ-----VHVAIKVIKRDNLMHQ----HMLQKEIQAMKKLRHKHIIRLHAVCSVGDPVYIITELMRKGNLQQYLRDSDEK

HTSLTIIWNWSVQIVTGMAYLEQKRFLHRDLACRNVLLAAGNKIKIGDFGLMRALPQEDDCYVMSEHKKVPFPWCAPESLRFRQFSHASDTWMFGVTLWE
  ..        |.  ||.||| ... ||||| ||||   .|  |.||||| | .   || |  |   ..|. | ||| .  | .|  || | ||. |.|
ALPIPHLLDFACQVAEGMCYLEEQNYIHRDLAARNVLVGDNNLCKVGDFGLARLI--KDDIYSPSHDHNIPYKWTAPEAANYRHYSQKSDVWSFGILLHE

MFSFGEDPWVGLNGSQILRKIDREGERLHQPDACPPDVYAMMLQCWDKTPAERPTFAALKEYLA
||. |  |. |.     . .||| | |.  | .|||.|. .||.|| . | .||.|..| | |.
MFTYGQCPYPGMTNHETFQQIDR-GYRMPCPAECPPEVHKLMLECWCRDPEQRPCFKDLREKLT
Kinase Ack.AA TK-Unique 146-406 32 1.9e-71 243.66 In-house 1-294 (294) Show / Hide 
Range on Protein: 146-406
Range on HMM: 1-294/294
Sequence Identity: 32% (98 aa)

ITMGLKLGDGSFGVVRRGEWSA--SPAGKVIPVAVKVLK-SDNLTQPGIIDDFFREVQAMHALD-HANLVRLYGVVL-SQ-PMMMITELAERGSLLDTLR
...| ..|.|.|| | ||| .    . .| . |||| || . ..|.    .||..| | | .|. | |.|...|.   |. |.|.| | ...|.|.. ||
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTD---KQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLR

KQCRH-----------------------TSLT--IIWNWSVQIVTGMAYLEQ--KRFLHRDLACRNVLLAAGNKIKIGDFGLMRALPQEDDCYVMS-EHK
.  .                        ....     .. .||  ||.||..  |.. ||||. |||||. ....||.|||. | .   .  |.|. . .
TCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYT-NGVYSMMCSQG

KVPFPWCAPESLR--FRQF-SHASDTWMFGVTLWEMFSFGEDPWVGLNGSQILRKIDREGERLHQPDAC-PPDVYAMMLQCWDKTPAERPTFAALKEYL
..|  |.|||||.   ... .  || |.|||..||.|..|. |  |.  ..|...| |.| |. ||. | ....|  | .|| . | |||.|...|  |
RIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECI-RDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase Ack.AA Frk 146-410 37 7.8e-70 238.32 In-house 1-260 (260) Show / Hide 
Range on Protein: 146-410
Range on HMM: 1-260/260
Sequence Identity: 37% (100 aa)

ITMGLKLGDGSFGVVRRGEWSASPAGKVIPVAVKVLKSDNLTQPGIIDDFFREVQAMHALDHANLVRLYGV-VLSQPMMMITELAERGSLLDTLR---KQ
| .  .|| | || |  | |        .||||| ||.  .      .|| || | |  | |. |..|| |  . .|...|||| ..|||.. |.   ..
IQLIRRLGSGQFGEVWEGLWNN-----TTPVAVKTLKPGTMDP----NDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDK

CRHTSLTIIWNWSVQIVTGMAYLEQKRFLHRDLACRNVLLAAGNKIKIGDFGLMRALPQEDD-CYVMSEHKKVPFPWCAPESLRFRQFSHASDTWMFGVT
 |.  .... . . |. .||||||.. ..||||| ||||.  .| .|| |||| | | ...   |      ..|  | |||  .  .|.  || | ||. 
GRQCQMQQLVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGIL

LWEMFSFGEDPWVGLNGSQILRKIDREGERLHQPDACPPDVYAMMLQCWDKTPAERPTFAALKEYLASMS
| |.  .|  |. |. . ..|  .|. | |. ||  ||. .| .||.|| . | .||||  |.  |    
LTEIITYGRMPYPGMTNAEVLQMVDH-GYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase Ack.AA S_TKc 146-414 24 2.9e-43 150.96 SMART 1-231 (231) Show / Hide 
Range on Protein: 146-414
Range on HMM: 1-231/231
Sequence Identity: 24% (68 aa)

ITMGLKLGDGSFGVVRRGEWSASPAGKVIPVAVKVLKSDNLTQPGIIDDFFREVQAMHALDHANLVRLYGVVLSQPMMMITELAER--GSLLDTLRKQCR
 ... |.| |.||.|... .          ||.|..|          ... ||.| ..  .| |.|.||.|  .. . |..|...   |.|.| ..|. |
YEILRKIGKGAFGKVYKCRHKK----TGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGR

H-----TSLTIIWNWSVQIVTGMAYLEQKRFLHRDLACRNVLLAAGNKIKIGDFGLMRALPQEDDCYVMSEHKKVPFPWCAPESLRFRQFSH-ASDTWMF
|      .   .. .  ||. ...|. .....||||   |.||     |||.|||| | |           .  .   ..||| |   .... ..| | .
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL---GYGKCKCDWWSC

GVTLWEMFSFGEDPWVGLNGSQILRKIDREGERLHQPDACPPDVYAMMLQCWDKTPAERPTFAALKE-YLASMSPPVM
|..|.||.. |. |.   .  ....||             .|..  .. .|..| |..|||   . .  .. .. | .
GCILYEMLC-GYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Ack.AA Pkinase 146-294 29 3.3e-19 69.01 Pfam 1-158 (293) Show / Hide 
Range on Protein: 146-294
Range on HMM: 1-158/293
Sequence Identity: 29% (48 aa)

ITMGLKLGDGSFGVVRRGEWSASPAGKVIPVAVKVLKSDNLTQPGIIDDFFR--EVQAMHALDHANLVRLYGVVL-SQPMMMITELAERG----SLLDTL
.. | |.| ||||.|... .  ..      ||||..| .  . ..     .|  |.| |. |.| | ||||...  .. . |..|..| |    .| | .
YHIGRKIGSGSFGCVYKCHHKGTGK----IVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI

R-KQCRHT--SLTIIWNWSVQIVTGMAYLEQKRFLHRDLACRNVLLAAGNKI----KIGDFGL
. .. .    |   . ..  ||. |..|. .....||||   |.|.   . |    ||.||||
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGL
Kinase Ack.AA Pkinase 316-406 19 8.9e-11 39.18 Pfam 176-293 (293) Show / Hide 
Range on Protein: 316-406
Range on HMM: 176-293/293
Sequence Identity: 19% (23 aa)

PWCAPESLR-FRQFSHASDTWMFGVTLWEMFSFGEDPWVGL------NGSQILRKIDREGERLHQPDACP-------------------PDVYAMMLQCW
...||| .|  .  ....| | .|..|.||.. |. |. |       .  |....| .   . . |  |.                   ..    .  |.
WYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCL

DKTPAERPTFAALKEY--L
.| |..|||.. ...   .
CKDPKKRPTAEQILQHPWF
UBA Ack.AA UBA 1056-1094 38 5.2e-05 23.89 SMART 1-38 (38) Show / Hide 
Range on Protein: 1056-1094
Range on HMM: 1-38/38
Sequence Identity: 38% (15 aa)

RHYKIDQLARLGVAGRPQCEQALQQTNWSLEVAAELLLN
.  |||||  .|     .|.|||...|| .|.|...|..
YEEKIDQLMEMGFDRE-ECVQALRACNWNVEMAMNWLFS
UBA Ack.AA UBA 1059-1092 34 0.000104 20.84 Pfam 5-38 (38) Show / Hide 
Range on Protein: 1059-1092
Range on HMM: 5-38/38
Sequence Identity: 34% (12 aa)

KIDQLARL-GVAGRPQCEQALQQTNWSLEVAAELL
...||  . |.    ||..||...|...| |.| |
MVKQLMEMTGFSMM-QCKKALRACNNNVERAVEWL
UBA Ack.AA UBA 1020-1055 24 0.125556 9.85 Pfam 1-35 (38) Show / Hide 
Range on Protein: 1020-1055
Range on HMM: 1-35/38
Sequence Identity: 24% (9 aa)

EQEKLQQLMQEL-GSSAVEQDVRNALRAASGDVGLAT
..|.. . ..|. |  . ..... ||||. ..|  |.
IDEEMVKQLMEMTG--FSMMQCKKALRACNNNVERAV