Gene CG8655 (Fruit Fly)

CG8655

Species: Fruit Fly
Alias: CDC 7-related, SFO123, CT25072, CG8655
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 6C3,

Classification

Group: Other
Family: CDC7

Sequence

Name Sequence Type Origin Length Description Download
CG8655.NA RNA None 1083 None Fasta, JSON
CG8655.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 256 Kinase domain by global Sugen HMM Fasta, JSON
CG8655.AA Protein Various 700 None Fasta, JSON

Protein domain

Protein domains of CG8655.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CG8655.AA CDC7 127-312 43 5.2e-120 360.75 In-house 1-232 (522) Show / Hide 
Range on Protein: 127-312
Range on HMM: 1-232/522
Sequence Identity: 43% (100 aa)

FDVHSRIGNGTFSTVLLGTLRRESHLP-------DSLRRKFAIKHHIPTSHPDRIMKELQCMTKMGGKENVVGIHCCMRYDASAAFVMPFMAHDRFQDFY
..||..||.||||.|...|..|..|..       .. |||||||||||||||.|||.||||.|.|||..||.|..||.||......|||...|..|||||
YKVHDKIGEGTFSSVYKATCQRQPHVNKFASHFWNYCRRKFAIKHHIPTSHPERIMNELQCLTRMGGHHNVMGMCCCFRYNDHVHIVMPYFPHCSFQDFY

TRMD--VPEIRQYMRNLLVALRHVHKFDVIHRDVKPSNFLYNRRRREFLLVDFGLAQHVNPP-AARSSGSAAAIA-------------------------
..|.  ..||..||.||..||||||.|..|||||||||||||||...|||||||||||....  .. | . ..                           
FHMNRDMEEIKHYMYNLFYALRHVHQFGIIHRDVKPSNFLYNRRTKKFLLVDFGLAQHMMDYNECSRSHQQSKMQQERCNQNKYHSISGNKALLRRPPPK

-----------AANNKNNNNNNNNNSKRPRER
             .| ||| ... ..|. ...
TQDQQHSNKNNVKRNYNNNQHHIKQGKDDKND
Kinase CG8655.AA CDC7 446-562 50 5.3e-59 174.29 In-house 306-422 (522) Show / Hide 
Range on Protein: 446-562
Range on HMM: 306-422/522
Sequence Identity: 50% (59 aa)

CVCFANPSVCLNCLMKKEVHASRAGTPGYRPPEVLLKYPDQTTAVDVWAAGVIFLSIMSTVYPFFKAPNDFIALAEIVTIFGDQAIRKTALALDRMITLS
| | . . .|  |. .|..||.||||||.|.||||||.||||||.|.|..||||||..|..||||.||.|..|||.|.||||   | | | ..   | .|
CCCYKSDKCCNCCMCPKQQHANRAGTPGFRAPEVLLKCPDQTTAIDIWSCGVIFLSLLSGRYPFFMAPDDMTALAQIMTIFGSEEIIKMAHFFGKKIECS

QRSRPLNLRKLCLRFRY
.   .  .|.|| . .|
HEFPAQDWRELCRCYWY
Kinase CG8655.AA S_TKc 127-644 12 3.4e-48 167.33 SMART 1-231 (231) Show / Hide 
Range on Protein: 127-644
Range on HMM: 1-231/231
Sequence Identity: 12% (66 aa)

FDVHSRIGNGTFSTVLLGTLRRESHLPDSLRRKFAIKHHIPTSHPDRIMKELQCMTKMGGKENVVGIHCCMRYDASAAFVMPFMAH--DRFQDFYTR---
....  || |.|..| ... ..         |..|||        ..|..|.|.. |  . .|.| .. ...   .  .|| .. .      |.  .   
YEILRKIGKGAFGKVYKCRHKK-------TGRIVAIKIIK-----EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

------MDVPEIRQYMRNLLVALRHVHKFDVIHRDVKPSNFLYNRRRREFLLVDFGLAQHVNPPAARSSGSAAAIAAANNKNNNNNNNNNSKRPRERESK
      ..  ..| ||. .. || . |.  .||||.||.| | ..   .  . ||||| ..                                       
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL---------------------------------------

GDVQQIALDAGLGGAVKRMRLHEESNKMPLKPVNDIAPSDAPEQSVDGSNHVQPQLVQQEQQQLQPQQQQQQQQQQQQSQQQQQPQQQSQQQHPQRQPQL
                                                                                                    
----------------------------------------------------------------------------------------------------

AQMDQTASTPSGSKYNTNRNVSAAAANNAKCVCFANPSVCLNCLMKKEVHASRAGTPGYRPPEVLLKYPDQTT-AVDVWAAGVIFLSIMSTVYPFFKAPN
                                                   .  ||| |..||||      .. ..|.|. |.|.   ..   ||     
--------------------------------------------------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCGYPPFP----

DFIALAEIVTIFGDQAIRKTALALDRMITLSQRSRPLNLRKLCLRFRYRSVFSDAKLLKSYESVDGSCEVCRNCDQYFFNCLCEDSDYLTEPLDAYECFP
.  .. ...                                                                                          .
QMQMMFKKIG-----------------------------------------------------------------------------------------S

PSAYDLLDRLLEINPHKRITAEEALK-------HPFF
|.| |.....|. .| ||.|| |||.       ||.|
PEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CG8655.AA Ciliate-E2 226-644 10 8.5e-32 106.42 In-house 146-365 (365) Show / Hide 
Range on Protein: 226-644
Range on HMM: 146-365/365
Sequence Identity: 10% (52 aa)

EIRQYMRNLLV---------------ALRHVHKFD-VIHRDVKPSNFLYNRRRREFLLVDFGLAQHVNPP---------------------------AAR
||...|. .|                ||.. |.   .|||| ||.| |.        ..||||.. ....                              
EIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQ--

SSGSAAAIAAANNKNNNNNNNNNSKRPRERESKGDVQQIALDAGLGGAVKRMRLHEESNKMPLKPVNDIAPSDAPEQSVDGSNHVQPQLVQQEQQQLQPQ
                                                                                                    
----------------------------------------------------------------------------------------------------

QQQQQQQQQQQSQQQQQPQQQSQQQHPQRQPQLAQMDQTASTPSGSKYNTNRNVSAAAANNAKCVCFANPSVCLNCLMKKEVHASRAGTPGYRPPEVLL-
                                                                             .. ... . .||||| .||.|  
----------------------------------------------------------------------------IIQQNMFNTICGTPGYMAPEILNG

KYPD-------QTTAVDVWAAGVIFLSIMSTVYPFFKAPNDFIALAEIVTIFGDQAIRKTALALDRMITLSQRSRPLNLRKLCLRFRYRSVFSDAKLLKS
|  |        ....|.|..|||.   ..  .||                                                                 
KKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF-----------------------------------------------------------------

YESVDGSCEVCRNCD-QYFFNCLCEDSDYLT--EPLD--AYECFPPSAYDLLDR----LLEINPHKRIT-AEEALKHPFF
            ... .. |.| . ..| ..  . ..   ..  .... ||. .    .|. .| |||| .|..|.||.|
---------QQQIKQCKIDFPCPEWQKD-TQCIQ-CKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase CG8655.AA CMGC 127-527 10 5.2e-27 85.02 In-house 1-371 (513) Show / Hide 
Range on Protein: 127-527
Range on HMM: 1-371/513
Sequence Identity: 10% (59 aa)

FDVHSRIGNGTFSTVLLGTLRRESHL-------PDSLRRKFAIK--HHIPTSHPD------------RIMKELQCMTKMG----------------GKEN
... ..|| ||...|  .. .|           .    .. |||     .  . .            |.  |.... ..                  ..|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

VVGIHCCMRYDA-----------------SAAFVMPFMAHDRFQDFYTR------------------------------MDVPEIRQYMRNLLVALR--H
.|... . ...                  .  .|. .| || .|  .                                . .  || ||. .| .|   .
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKY

VHKFD--VIHRDVKPSNFLYNRRRREF-------------------LLVDFGLAQHVNPP----------------AARSSGSAAAIAAANNKNNNNNNN
 |. .  .|||| ||.| | | . . .                    . ||||| ...|.                .                       
CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNK-----------------------

NNSKRPRERESKGDVQQIALDAGLGGAVKRMRLHEESNKMPLKPVNDIAPSDAPEQSVDGSNHVQPQLVQQEQQQLQPQQQQQQQQQQQQSQQQQQPQQQ
                                                                                                    
----------------------------------------------------------------------------------------------------

SQQQHPQRQPQLAQMDQTASTPSGSKYNTNRNVSAAAANNAKCVCFANPSVCLNCLMKKEVHASRAGTPGYRPPEVLLKYPDQT---------TAVDVWA
                                                     .   . . . ..  |  ||.||.|| ... |         |..|.|.
-----------------------------------------------------DD-KPNRPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWS

AGVIFLSIMST-------VYPFFK-----------APNDFIALAEIVTIFG
.| ||  ..          .|.|.             ..   |..|. ..|
VGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLG
Kinase CG8655.AA CDC7 613-644 87 1.3e-25 72.24 In-house 491-522 (522) Show / Hide 
Range on Protein: 613-644
Range on HMM: 491-522/522
Sequence Identity: 87% (28 aa)

FPPSAYDLLDRLLEINPHKRITAEEALKHPFF
||..|||||||.||.|||||||||||||||||
FPDEAYDLLDRCLEMNPHKRITAEEALKHPFF
Kinase CG8655.AA CK2 127-273 28 1.1e-22 63.86 In-house 1-143 (288) Show / Hide 
Range on Protein: 127-273
Range on HMM: 1-143/288
Sequence Identity: 28% (42 aa)

FDVHSRIGNGTFSTVLLGTLRRESH-LPDSLRRKFAIKHHIPTSHPDRIMKELQCMTKMGGKENVVGIHCCMRYDAS--AAFVMPFMAHDRFQDFYTRMD
. | ..|| | .| |  |   . .. .      |  ||   |     .|  |.. .... | .|.. .   ..  .|  .| | ...    |.  | ...
YEVIRKIGRGKYSEVFEGINIKNNEKC------KIVIKILKPVKK-KKIKREIKILENLNGGPNIIKLYDIVKDPYSKVPALVFEYVNNTDFRQLYQTLT

VPEIRQYMRNLLVALRHVHKFDVIHRDVKPSNFLYNRRRREFLLVDFGLA
 ..|| ||..|| ||   |.  ..||||||.| . . ..|.  |.| |||
DYDIRYYMFELLKALDYCHSMGIMHRDVKPHNIMIDHEKRKLRLIDWGLA
Kinase CG8655.AA CAMK 132-498 10 9.1e-22 66.28 In-house 1-323 (425) Show / Hide 
Range on Protein: 132-498
Range on HMM: 1-323/425
Sequence Identity: 10% (51 aa)

RIGNGTFSTVLLGTLRRES------HLPDSLRRKFAIKH----HIPTSH--------------------------PDRIMKELQCMTKMGG------KEN
 .| |.|..| |.. ..        |.     .|.|||      .. ..                           .....|...| |. |       .|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTN-GQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPN

VVGIHCCMRY-------------------DASAAFVM---PFMAHD----R-FQDFYTR-----------------MDVPEIRQYMRNLLVALRHVHKFD
.. ..  .                     |    .||    ..       . |.    .                 ..  | |.|.| .. |... |. .
IIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VIHRDVKPSNFLYNRRRREF-------------L---LVDFGLAQHVNP------------------PAARSSGSAAAIAAANNKNNNNNNNNNSKRPRE
..||| || | |.. . ...                 ..|||.|....|                                                   
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQW--------------------------------

RESKGDVQQIALDAGLGGAVKRMRLHEESNKMPLKPVNDIAPSDAPEQSVDGSNHVQPQLVQQEQQQLQPQQQQQQQQQQQQSQQQQQPQQQSQQQHPQR
                                                                                                    
----------------------------------------------------------------------------------------------------

QPQLAQMDQTASTPSGSKYNTNRNVSAAAANNAKCVCFANPSVCLNCLMKKEVHASRAGTPGYRP-PEVLLK-------------YPDQTTAVDVWAAGV
                                             .   . .    . |||.| . ||||..              |  . ..|.|..||
---------------------------------------------TTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGV

I
|
I
Kinase CG8655.AA Pkinase 127-273 20 9.4e-21 74.46 Pfam 1-159 (293) Show / Hide 
Range on Protein: 127-273
Range on HMM: 1-159/293
Sequence Identity: 20% (35 aa)

FDVHSRIGNGTFSTVLLGTLRRESHLPDSLRRKFAIKHHIPTSHPDRIMK-------ELQCMTKMGGKENVVGIHCCMRYDASAAFVMPFMAHD----RF
. ....|| |.|..| ... . ...       ..|.|  |. .| .  ..       |.| | .. . .|.| ........ .  .||... ..      
YHIGRKIGSGSFGCVYKCHHKGTGK-------IVAVK-IIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDL

Q-----DFYTRM--DVPEIRQYMRNLLVALRHVHKFDVIHRDVKPSNFLYNRRRREF----LLVDFGLA
      . ....  .  |.. ||. .| .| . |.  .||||.||.|.|.. .. .      . |||||
FDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLA
Kinase CG8655.AA Ciliate-E2a 610-644 45 6.5e-19 52.33 In-house 241-275 (275) Show / Hide 
Range on Protein: 610-644
Range on HMM: 241-275/275
Sequence Identity: 45% (16 aa)

YECFPPSAYDLLDRLLEINPHKRITAEEALKHPFF
.|... ...||. ..|| .| |||||..||.||.|
WEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase CG8655.AA Ciliate-E2-Unclassified 226-510 10 5.5e-18 59.0 In-house 139-271 (352) Show / Hide 
Range on Protein: 226-510
Range on HMM: 139-271/352
Sequence Identity: 10% (32 aa)

EIR-----QYMRNLLVALRHVHKFD-VIHRDVKPSNFLYNRRRR--EFLLVDFGLAQ---------HVNPPAARSSGSAAAIAAANNKNNNNNNNNNSKR
...     .|.. .|..| . |.   .|||| ||.| |..   .  .  . |||..          . .                               
QAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQ-------------------------------

PRERESKGDVQQIALDAGLGGAVKRMRLHEESNKMPLKPVNDIAPSDAPEQSVDGSNHVQPQLVQQEQQQLQPQQQQQQQQQQQQSQQQQQPQQQSQQQH
                                                                                                    
----------------------------------------------------------------------------------------------------

PQRQPQLAQMDQTASTPSGSKYNTNRNVSAAAANNAKCVCFANPSVCLNCLMK-------KEVHASRAGTPGYR----PPEVLLK-YPDQT--TAVDVWA
                                                    .       ..   ...|||.|     .|||| .  .|..   ..|.|.
----------------------------------------------------QQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWS

AGVIFLSIMSTVYPFF
 |||.  ..   |||.
LGVILYEMLFGYYPFY
Kinase CG8655.AA CMGC 614-644 58 4e-17 51.94 In-house 483-513 (513) Show / Hide 
Range on Protein: 614-644
Range on HMM: 483-513/513
Sequence Identity: 58% (18 aa)

PPSAYDLLDRLLEINPHKRITAEEALKHPFF
.| | |||...|...|.||||||.||.||.|
DPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase CG8655.AA CDK 619-644 57 4.3e-15 44.56 In-house 259-284 (284) Show / Hide 
Range on Protein: 619-644
Range on HMM: 259-284/284
Sequence Identity: 57% (15 aa)

DLLDRLLEINPHKRITAEEALKHPFF
|||...|  .|.|||.||.||.||.|
DLLNKMLCYDPKKRISAEQALQHPYF
Kinase CG8655.AA ERK 615-644 56 3.6e-14 49.34 In-house 278-307 (307) Show / Hide 
Range on Protein: 615-644
Range on HMM: 278-307/307
Sequence Identity: 56% (17 aa)

PSAYDLLDRLLEINPHKRITAEEALKHPFF
| | |||...|...| ||||.||.|.||.|
PQAIDLLEKMLVFDPDKRITVEECLEHPYF
Kinase CG8655.AA CAMK1 231-499 11 8.1e-14 36.49 In-house 114-206 (276) Show / Hide 
Range on Protein: 231-499
Range on HMM: 114-206/276
Sequence Identity: 11% (32 aa)

MRNLLVALRHVHKFDVIHRDVKPSNFLYNRRRREFLLV----DFGLAQHVNPPAARSSGSAAAIAAANNKNNNNNNNNNSKRPRERESKGDVQQIALDAG
|...| |. . |. .. ||| || | ||     .. ..    ||||.. ...                                                
MKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDEN---------------------------------------------

LGGAVKRMRLHEESNKMPLKPVNDIAPSDAPEQSVDGSNHVQPQLVQQEQQQLQPQQQQQQQQQQQQSQQQQQPQQQSQQQHPQRQPQLAQMDQTASTPS
                                                                                                    
----------------------------------------------------------------------------------------------------

GSKYNTNRNVSAAAANNAKCVCFANPSVCLNCLMKKEVHASRAGTPGYRPPEVLLK-----YPDQTTAVDVWAAGVIF
                                     .   . |||||  ||||       |     |.|.| .|||.
-------------------------------------LMKTACGTPGYVAPEVLECKKDKPY---DKACDMWSIGVIT
Kinase CG8655.AA CK2 615-644 50 2e-13 35.67 In-house 259-288 (288) Show / Hide 
Range on Protein: 615-644
Range on HMM: 259-288/288
Sequence Identity: 50% (15 aa)

PSAYDLLDRLLEINPHKRITAEEALKHPFF
| | |.||..| . . .|||| ||..||.|
PEAIDFLDKMLRYDHQERITAKEAMEHPYF
Kinase CG8655.AA CAMK 613-644 34 8.1e-13 36.92 In-house 394-425 (425) Show / Hide 
Range on Protein: 613-644
Range on HMM: 394-425/425
Sequence Identity: 34% (11 aa)

FPPSAYDLLDRLLEINPHKRITAEEALKHPFF
. ... ||. ..|. .| ||.|.|..|.||..
VSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase CG8655.AA CAMK1 619-644 42 3.1e-12 31.79 In-house 251-276 (276) Show / Hide 
Range on Protein: 619-644
Range on HMM: 251-276/276
Sequence Identity: 42% (11 aa)

DLLDRLLEINPHKRITAEEALKHPFF
|..  .|| .| ||.|.|..|.||..
DFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase CG8655.AA Ciliate-E2a 221-278 29 3.3e-11 29.28 In-house 95-161 (275) Show / Hide 
Range on Protein: 221-278
Range on HMM: 95-161/275
Sequence Identity: 29% (20 aa)

RMDVP--EIRQYMRNLL-VALRHVHKFDVIHRDVKPSNFLYN---RRR---REFLLVDFGLAQHVNP
|..    ||...|..||  .| ..|.  ..||| || |.|..          .  ..|||||. ...
RFFEEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDK
Kinase CG8655.AA Pkinase 614-644 38 4.8e-11 40.12 Pfam 263-293 (293) Show / Hide 
Range on Protein: 614-644
Range on HMM: 263-293/293
Sequence Identity: 38% (12 aa)

PPSAYDLLDRLLEINPHKRITAEEALKHPFF
.... |.....|. .|.||.|||..|.||.|
SEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase CG8655.AA CK2 468-527 30 5.7e-11 28.21 In-house 155-214 (288) Show / Hide 
Range on Protein: 468-527
Range on HMM: 155-214/288
Sequence Identity: 30% (18 aa)

RAGTPGYRPPEVLLKYPDQTTAVDVWAAGVIFLSIMSTVYPFFKAPNDFIALAEIVTIFG
| ..  |..|| |. | .   ..|.|. |..| |..    |||.  .   .| .||...|
RVASRYYKGPELLVDYQYYDYSLDMWSLGCMFASMIFKKEPFFHGHDNYDQLVKIVKVLG
Kinase CG8655.AA Pkinase 467-509 32 6.7e-11 39.63 Pfam 170-212 (293) Show / Hide 
Range on Protein: 467-509
Range on HMM: 170-212/293
Sequence Identity: 32% (14 aa)

SRAGTPGYRPPEVLLKYPDQTTAVDVWAAGVIFLSIMSTVYPF
...|||.|..|||...... ...||.|..|.|.   ..   ||
TFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPF
Kinase CG8655.AA Ciliate-E2-Unclassified 619-644 57 4.8e-10 31.07 In-house 327-352 (352) Show / Hide 
Range on Protein: 619-644
Range on HMM: 327-352/352
Sequence Identity: 57% (15 aa)

DLLDRLLEINPHKRITAEEALKHPFF
||| ..|. || ||||.|..|.||.|
DLLQKMLKKNPNKRITFEQILNHPWF
Kinase CG8655.AA ERK 474-499 46 1.3e-09 32.16 In-house 182-207 (307) Show / Hide 
Range on Protein: 474-499
Range on HMM: 182-207/307
Sequence Identity: 46% (12 aa)

YRPPEVLLKYPDQTTAVDVWAAGVIF
||.||..|.... |.|.|.|..|.||
YRAPEIMLSWQKYTKAMDIWSCGCIF
Kinase CG8655.AA CDK 205-273 33 4.7e-09 24.94 In-house 95-160 (284) Show / Hide 
Range on Protein: 205-273
Range on HMM: 95-160/284
Sequence Identity: 33% (25 aa)

FVMPFMAHD--RFQDFYTRMDVPEIRQYMRNLLVALRHVHKFDVIHRDVKPSNFLYNRRRR----EFLLVDFGLA
.|...| ||   . |         |. ||. || .| . |.  ..||| ||.| |.|..         . |||||
MVFEYMDHDLKKYMD---------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLA
Kinase CG8655.AA Ciliate-E2a 467-499 41 2.1e-08 20.87 In-house 169-206 (275) Show / Hide 
Range on Protein: 467-499
Range on HMM: 169-206/275
Sequence Identity: 41% (16 aa)

SRAGTPGYRPPEVLLKYPD---Q---TTAVDVWAAGVIF
.. ||||| .||| |....   .   .| .|.| .||||
QKCGTPGYVAPEV-LNNKEVLKHKQYDTKCDMWSCGVIF
Kinase CG8655.AA CDK 474-499 42 6.4e-08 21.26 In-house 185-212 (284) Show / Hide 
Range on Protein: 474-499
Range on HMM: 185-212/284
Sequence Identity: 42% (12 aa)

YRPPEVLLKYPDQT--TAVDVWAAGVIF
||.||.||   . .  |..|.|..| ||
YRAPELLLGSKHYSGGTPIDMWSVGCIF
Kinase CG8655.AA CAMK1 127-148 36 3e-06 14.33 In-house 1-22 (276) Show / Hide 
Range on Protein: 127-148
Range on HMM: 1-22/276
Sequence Identity: 36% (8 aa)

FDVHSRIGNGTFSTVLLGTLRR
. ....||.|.||.| |.| ..
YEFGKEIGRGAFSEVYLCTHKE
Kinase CG8655.AA TyrKc 127-322 12 1.6e-05 -133.32 SMART 1-280 (280) Show / Hide 
Range on Protein: 127-322
Range on HMM: 1-280/280
Sequence Identity: 12% (38 aa)

FDVHSRIGNGTFSTVLLGTLRRESHLPDSLRRKFAIKHHIPTSHPDRIMKELQCMTKMG-GKENVVGIHCCMRYD-------ASAAFVMPFMAHDRFQDF
      .|.| | .| .||..          .. |.|   . .    .|.|.. |.| |   .|.| .. . . .            || .|.|   .|.
ITLGKKLGEGAFGEVYKGTWK----------IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

--YTR--MDVPEIRQYMRNLLVALRHVHKFDVIHRDVKPSNFLYNRRRREFLLV---DFGLAQHVNPP----------------AAR-------------
  ..|    ...  ...       .. |.  .||||    | |.....     |   ||||.  .                    ..             
LRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

----------------------------SSG------SAAAIAAANNKNNNNNNNNN---------------------SKRPRERESKGDVQQIA
                             .|      |.. . .   . .      |                        | .| .  .. .. 
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase CG8655.AA ERK 234-259 53 0.002641 8.39 In-house 117-142 (307) Show / Hide 
Range on Protein: 234-259
Range on HMM: 117-142/307
Sequence Identity: 53% (14 aa)

LLVALRHVHKFDVIHRDVKPSNFLYN
.| .| ..|  .||||| |||| | |
ILCGLKYIHSANVIHRDLKPSNILVN
Kinase CG8655.AA Ciliate-E2a 127-149 26 0.013284 3.51 In-house 1-23 (275) Show / Hide 
Range on Protein: 127-149
Range on HMM: 1-23/275
Sequence Identity: 26% (6 aa)

FDVHSRIGNGTFSTVLLGTLRRE
....  ||.|.|  | | .....
YKFIKKIGKGNFGSVYLAQHKQT
Kinase CG8655.AA Ciliate-E2-Unclassified 127-143 29 0.035608 3.37 In-house 1-17 (352) Show / Hide 
Range on Protein: 127-143
Range on HMM: 1-17/352
Sequence Identity: 29% (5 aa)

FDVHSRIGNGTFSTVLL
. ..  ||.| |..| .
YKIIKQIGQGGFGKVYK
Kinase CG8655.AA Ciliate-E2 127-144 27 0.041288 3.02 In-house 1-18 (365) Show / Hide 
Range on Protein: 127-144
Range on HMM: 1-18/365
Sequence Identity: 27% (5 aa)

FDVHSRIGNGTFSTVLLG
....  ||.|.|..| ..
YKFIKKIGQGNFGSVYKC