Gene CG11221 (Fruit Fly)

CG11221

Species: Fruit Fly
Alias: SFO093, CG11221, PKN
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 27A1--2,

Classification

Group: Other
Family: NKF1

Sequence

Name Sequence Type Origin Length Description Download
CG11221.AA Protein Various 456 None Fasta, JSON
CG11221.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 262 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of CG11221.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CG11221.AA NKF1 101-362 53 4.2e-182 611.28 In-house 1-269 (269) Show / Hide 
Range on Protein: 101-362
Range on HMM: 1-269/269
Sequence Identity: 53% (144 aa)

YNIEKTLAEGCFAKILLCRHRPTNTLVVLKAVHAELTTIKEFQKEFHYNYELSHHHHILSAYAVAFQTMD--YYVFAMEHAPYGDLASNIG---PNGLHE
|.|...|.|||..|||||.||...| ..||.|....|..|.|..||.|...|||||||...|.|.|||||  |||||.|.||.|||...|.   ..||.|
YEIIRQLGEGCYGKILLCEHRQSGTRMALKFVPKPQTKLKDFHREFCYGCCLSHHHHIVTTYDVMFQTMDDTYYVFAQEYAPCGDLMEMIQPTNQRGLPE

NACKLISEQLSSALGFMHSKNLVHRDLKIENILVFTP-DFTRVKLCDFGATTKKGLLVHKVKHTWTSCVPPEQLELIKNERFQCLPVSDSWQFGILLYNI
|.||....||.|||.||||.||||||.|.||.|||.| |..||||||||.|...|..|..|||||..|.|....||.|||.|.|.|..|.||||.|....
NYCKRCVAQLASALDFMHSRNLVHRDIKPENVLVFDPNDCQRVKLCDFGHTRPRGCTVRRVKHTWPYCAPEVCQELPKNEGFPCDPSHDVWQFGVLIFCC

LTGNPPWQSADWVKDQSYANFMKYEQRK-TTKVPDNFRRFSPRLMRCFRKYLSHDPEDRCKITEVAKYM
|||..|||.|||..|..|..||....|| ....|...|||.||.||||||.|...||.|.......|||
LTGCFPWQKADWMCDPCYEWFMWWQRRKQPPMMPQPWRRFTPRAMRCFRKLLTPHPERRWPVKMMHKYM
Kinase CG11221.AA S_TKc 101-367 24 4.5e-39 137.03 SMART 1-231 (231) Show / Hide 
Range on Protein: 101-367
Range on HMM: 1-231/231
Sequence Identity: 24% (71 aa)

YNIEKTLAEGCFAKILLCRHRPTNTLVVLKAVHAELTTIKEFQKEFHYNYELSHHHHILSAYAVAFQTMDYYVFAMEHAPY--GDLASNIGPNG------
| | ... .| |.|  .|||. |. .| .| ..      . ...|     .  || .|   | |     |.. . ||...   ||| . |  .|      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK--HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LHENACKLISEQLSSALGFMHSKNLVHRDLKIENILVFTPDFTRVKLCDFGATTKKGLLVHKVKHTWTSCV-----PPEQLELIKNERFQCLP-VSDSW
 ..|  .. .  |. .|| ..||.. .||||| ||||. .    ..|.||||  ..            | |.     .|| |        .  .  .| |
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL----------TTFCGTPWYMAPEVL--------GYGKCKCDWW

QFGILLYNILTGNPPWQSADWVKDQSYANFMKYEQRKTTKVPDNFRRFSPRLMRCFRKYLSHDPEDRCKITEVAK----YMKDRWV
 .|..||  |.| ||..      .|   . ..                || .    || |  |||.|  . |. .     ... |.
SCGCILYEMLCGYPPFP-----QMQMMFKKIG----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CG11221.AA CAMK 106-243 19 1.9e-29 91.44 In-house 1-241 (425) Show / Hide 
Range on Protein: 106-243
Range on HMM: 1-241/425
Sequence Identity: 19% (48 aa)

TLAEGCFAKILLCRHRPTN------------TLVVLKAVHAE-----------------------------LTTIKEFQKEFHYNYELS------HHHHI
|| .| |.|  ||.|. |.            . |  | .  .                               . |....| .    |.      .| .|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LSAYAVAFQ-----------TMDY--------YVFAM---EHAPYG----DLASNI---GPNG-------------LHENACKLISEQLSSALGFMHSKN
.. | |              | ..        ... |   |... |    || . |   |..|             ..|  .. .  |. ||. ..||.|
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

LVHRDLKIENILVFTPDF---------------TRVKLCDFG
 |||||| ||||. . .                  .|..|||
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFG
Kinase CG11221.AA CAMKL 101-243 26 4.2e-27 83.4 In-house 1-174 (297) Show / Hide 
Range on Protein: 101-243
Range on HMM: 1-174/297
Sequence Identity: 26% (47 aa)

YNIEKTLAEGCFAKILLCRH-RPTNTLVVLKAVHAELTTIKEFQK----------------EFHYNYELS--HHHHILSAYAVA----F--QTMDYYVFA
|.|.||| .| |.|  |..| | |.. |  | .. . .. ... |                | .    |.   | .| . | |     .  .| ....  
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIET-KKIYLV

MEHAPYGD--LASNI---GPNG--LHENACKLISEQLSSALGFMHSKNLVHRDLKIENILVFTPDFTRVKLCDFG
||... |.  |   |   |  .  ..|. .. .  |. ||. ..||.. ||||.| ||||.   .   .|..|||
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFG
Kinase CG11221.AA Pkinase 101-243 28 1.5e-26 95.01 Pfam 1-157 (293) Show / Hide 
Range on Protein: 101-243
Range on HMM: 1-157/293
Sequence Identity: 28% (45 aa)

YNIEKTLAEGCFAKILLCRHRPTNTLVVLKAVHAELTTIKEFQK-----EFHYNYELSHHHHILSAYAVAFQTMDYYVFAMEHAPYG----DLASNIG--
| |.... .| |..  .|.|. |. .|..| .  . .  .. |      | ..  .| .| .|.  | . |.. |.. . ||... |    ||.. |   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDW-FEDKDHIYMVMEYCEGGLYVMDLFDYISTW

-PNGL--HENACKLISEQLSSALGFMHSKNLVHRDLKIENILVFTPDFTR---VKLCDFG
  ...   |. || .  |. ..| ..||.. .||||| ||||.   . .    ||.||||
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFG
Kinase CG11221.AA Ciliate-E2 101-360 17 1.9e-24 80.79 In-house 1-361 (365) Show / Hide 
Range on Protein: 101-360
Range on HMM: 1-361/365
Sequence Identity: 17% (70 aa)

YNIEKTLAEGCFAKILLCRHRPTNTLV-----------------VLKAVHAELTT----IKEFQKEFHYNYELSH---------------HHHILSAYAV
|.. | . .|.|... .|... .. ..                 | .   |  .     |... .| | . |. .               | .|.  | .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

AFQ--TMDYYVFAMEHAPYGDLASNI-------------GPNGLHENACKLISEQLSS---------------ALGFMHSKN-LVHRDLKIENILVFTPD
 ||  . ... . || . .||| . |             . . . |. .| |..|. .               || ..||||  .|||.| ||||.    
-FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

FTRVKLCDFGATTK--------------KGLLVHKVKHTWTSC--------------------VPPEQLELIKNE----RFQCLPVSDSWQFGILLYNIL
   .|..|||  .|              | ..  |.. . |.                     ..|| |.  |..    . .    .| | .|..||  |
---IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEML

TGNPPWQSADWVKDQSYANFMKYEQRKTTKVPDNFR-------------------RFSPRLMRCFRK----YLSHDPEDRCK-ITEVAK
.|.||.                  |..  . . .|.                     |.  .  ..|     |  ||| |   . .. .
FGKPPF------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN
Kinase CG11221.AA Ciliate-E2-Unclassified 101-300 21 2.1e-24 81.54 In-house 1-269 (352) Show / Hide 
Range on Protein: 101-300
Range on HMM: 1-269/352
Sequence Identity: 21% (58 aa)

YNIEKTLAEGCFAKILLCRHRPTNTLV-------VLKAVH-----------AELTTIKEFQKEFHYN-YE-------LSHHHHILSAYAVAFQTMDYYVF
|.| |.. .|.|.|. .|.|. .. ..       . . ..            |...... .| .| . |.       |.| | ..  .  .||. ..  .
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

AMEHAPYGDLASNIGP------------------NGLHENACK-----LISEQLSSALGFMHSKN-LVHRDLKIENILVFTPDFT--RVKLCDFGATTKK
 || ...|||   |                    . . |...|      .  |. ..| ..|.||  .|||.| |||| |. .    ..|..|||   | 
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENIL-FDNNGKNYYIKIIDFGISKKY

GLL------------VHKVKHTWTSCVPPEQL------ELIKNERFQCLPV--SDSWQFGILLYNILTGNPP
.              . | ...|| |  |. .      |.....         .| | .|..|| .|.|..|
QQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYP
Kinase CG11221.AA DCAMKL 155-243 36 6.2e-19 55.04 In-house 74-164 (279) Show / Hide 
Range on Protein: 155-243
Range on HMM: 74-164/279
Sequence Identity: 36% (34 aa)

HHHILSAYAVAFQTMDYYVFAMEHAPYGDLASNIGPNG-LHENACKLISEQLSSALGFMHSKNLVHRDLKIENILVFT--PDFTRVKLCDFG
| || . | . .. ..||   ||.. .|||   |  |.   |.   ..  .| .|| ..|..| ||||.| || ||       . .||||||
HPHIIQLYEHWDTETHYYLV-MEYVQGGDLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFG
Kinase CG11221.AA CAMK-Unique 155-243 25 9.6e-19 58.31 In-house 75-218 (363) Show / Hide 
Range on Protein: 155-243
Range on HMM: 75-218/363
Sequence Identity: 25% (37 aa)

HHHILSAYAV---AFQTMD---------------YYVFAMEHAPYGDLASNIGP--------------------NG-LHE--NACKLISEQLSSALGFMH
|..|.  | .    |.. .               |..  ||... ||| . |                      .| . |  .   .|. .| ||. .||
HPNIIKLYDWNNPIFCDRKYPLCDLIIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMH

SKNLVHRDLKIENILVFTP--D------------FTRVKLCDFG
|.. |||||| |||.| ..  |            ....||||||
SQDIVHRDLKLENIMVCYSFKDNNHHRDFPYDWSNWHIKLCDFG
Kinase CG11221.AA CMGC 101-243 16 2.9e-17 52.39 In-house 1-249 (513) Show / Hide 
Range on Protein: 101-243
Range on HMM: 1-249/513
Sequence Identity: 16% (42 aa)

YNIEKTLAEGCFAKILLCRH--------------RPTNTLVVLKAVH-AELTTIKEF------------QKEFHYNYELS----------------HHHH
| | | . || ...   ||.              . || .| .| .  ..  .. .             . |  .  .|.                ||..
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

ILSAYAVAFQT----------------MDYYVFAMEHAPY---GDLASNI------GPNGLHENA------------CKLIS------EQLSSALG--FM
|.. | .                    ...  . .|. ..   . . .|       .|..| |              .| ..       |.  .|   ..
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSKN--LVHRDLKIENILVFTPDF------------------TRVKLCDFG
||..   .||||| ||||.                        |.|.||||
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFG
Kinase CG11221.AA TKL 107-302 14 5.7e-17 57.65 In-house 1-290 (364) Show / Hide 
Range on Protein: 107-302
Range on HMM: 1-290/364
Sequence Identity: 14% (42 aa)

LAEGCFAKILLCRHRPTN--------TLVVLKAVHA------------------------ELTTIKEFQKEFHYNYELSH---HHHILSAYAVAFQTMD-
. .| |...   ..| ..        . |. |  .                         . .... |.... .   . .   | .|.. ......  . 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-----------YYVFAMEHAPYGD-LASNIGPNGLHENACKLISEQLSSALGFMHS--------KNLVHRDLKIENILVFTP------------DFTRVK
           .. . || .| |. |   .       .    .. . .... ..||        ....||||| .||||.              .  ..|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

LCDFGATTKKGLL---------------------VHKVKHTWTSCVPPEQLE-LIKNER----------FQCLPVSDSWQFGILLYNILTGNPPWQ
.||||  . .                         .  .  ..   .|| |.  ....           |.  . .| . |||.|. |||. .|..
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYY
Kinase CG11221.AA MARK 193-243 46 1e-12 38.06 In-house 101-151 (262) Show / Hide 
Range on Protein: 193-243
Range on HMM: 101-151/262
Sequence Identity: 46% (25 aa)

LHENACKLISEQLSSALGFMHSKNLVHRDLKIENILVFTPDFTR---VKLCDFG
|||. .. |  |. ||. ..|||| ||||.| ||||.   |  .   .|..|||
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILI---DENGNHNIKIIDFG
Kinase CG11221.AA TyrKc 101-362 21 5.4e-12 -28.81 SMART 1-280 (280) Show / Hide 
Range on Protein: 101-362
Range on HMM: 1-280/280
Sequence Identity: 21% (63 aa)

YNIEKTLAEGCFAKILLCRHRPTNTLVVLKAVHAELTTIKEFQKEFHYNYEL-SHHHHILSAYAVAFQTM------DYYVFAMEHAPYGDLASNIGPNG-
   .|.| ||.| .. ... .   . |  | ....   ...| .|     .|  || .|.  |.|. |        . .   ||..|.||| . .  .. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

-LHENACKLISEQLSSALGFMHSKNLVHRDLKIENILVFTPDFTRVKLCDFGATTKKGLL--------VHKVK---HTWT-SCV---PPEQLELIKNERF
 |       .. | ..   . ||||..||||   |.||  .   .|| .||| . . .          . ..|   .. |   .   .|| .        
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-----NYG

QCLPVSDSWQFGILLYNILT-GNPPWQS---ADWVKDQSYANFMKYEQRKTTKVP--------DNFRRFSPRLMRCFRKYLSHDPEDRCKITEVAKYM
 . . || | ||.... |.| | .|.        ...|   .. |   |                   ..    .| .    .|||||.  .|. ...
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWH----EDPEDRPTFSEIHECF
Kinase CG11221.AA MARK 101-130 36 4.9e-07 19.22 In-house 1-30 (262) Show / Hide 
Range on Protein: 101-130
Range on HMM: 1-30/262
Sequence Identity: 36% (11 aa)

YNIEKTLAEGCFAKILLCRHRPTNTLVVLK
| . ||. .| .||  |..|..|.. | .|
YKMLKTIGHGSYAKVKLACHKHTGRKVAIK
Kinase CG11221.AA CAMKL 283-367 22 5e-06 15.01 In-house 218-297 (297) Show / Hide 
Range on Protein: 283-367
Range on HMM: 218-297/297
Sequence Identity: 22% (20 aa)

DSWQFGILLYNILTGNPPWQSADWVKDQSYANFMKYEQRKTTKVPDNFRRF---SPRLMRCFRKYLSHDPEDRCKITEVAKYMKDRWV
| |  |..||....|. |.  ..  |    ..   |. .|. .   ... .   | .. .  || | ..||.| .| ..   |...|.
DIWSCGVILYAMVCGYLPFDDDTYNK--QGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQI---MNHPWM
Kinase CG11221.AA Pkinase_Tyr 201-243 39 0.001549 12.6 Pfam 116-156 (270) Show / Hide 
Range on Protein: 201-243
Range on HMM: 116-156/270
Sequence Identity: 39% (17 aa)

ISEQLSSALGFMHSKNLVHRDLKIENILVFTPDFTRVKLCDFG
.. | .... . .|||..||||   |.||   ..  || ||||
MCWQIAKGMEYLESKNCIHRDLAARNCLVTE-NN-VVKICDFG
Kinase CG11221.AA CAMK-Unique 277-300 50 0.003399 6.17 In-house 269-292 (363) Show / Hide 
Range on Protein: 277-300
Range on HMM: 269-292/363
Sequence Identity: 50% (12 aa)

QCLPVSDSWQFGILLYNILTGNPP
|| | ||.|  | ..|  |.|.||
QCSPASDIWSLGVIMYYMLCGCPP
Kinase CG11221.AA MARK 345-367 39 0.006937 5.46 In-house 243-262 (262) Show / Hide 
Range on Protein: 345-367
Range on HMM: 243-262/262
Sequence Identity: 39% (9 aa)

LSHDPEDRCKITEVAKYMKDRWV
| ..||.| .|.|.   ||..|.
LTVNPEERPTIEEI---MKHPWM
Kinase CG11221.AA Pkinase_Tyr 101-184 24 0.013463 9.42 Pfam 1-94 (270) Show / Hide 
Range on Protein: 101-184
Range on HMM: 1-94/270
Sequence Identity: 24% (23 aa)

YNIEKTLAEGCFAKILLCRHR----PTNTLVVLKAV--HAELTT--IKEFQKEFHYNYELSHHHHILSAYAVAFQTMDY--YVFAMEHAPYGDL
  . |.| ||.| .. ... .     |.. |  | .  .|      ...| .|     .| ||..|.. |.|     .   .   ||..|.|||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDL
Kinase CG11221.AA DCAMKL 101-130 35 0.045152 1.62 In-house 1-31 (279) Show / Hide 
Range on Protein: 101-130
Range on HMM: 1-31/279
Sequence Identity: 35% (11 aa)

YNIEKTLAEGCFAKILLCRHRPTN-TLVVLK
| | ..   | || . .|||| |. .   .|
YQIGRIIGDGNFAVVHECRHRETGDHKYAMK
Kinase CG11221.AA CAMK 288-305 38 0.078709 0.87 In-house 321-338 (425) Show / Hide 
Range on Protein: 288-305
Range on HMM: 321-338/425
Sequence Identity: 38% (7 aa)

GILLYNILTGNPPWQSAD
|..||  |.| ||... .
GVILYIMLCGYPPFYGDC
Kinase CG11221.AA DCAMKL 283-305 47 0.106454 0.44 In-house 201-223 (279) Show / Hide 
Range on Protein: 283-305
Range on HMM: 201-223/279
Sequence Identity: 47% (11 aa)

DSWQFGILLYNILTGNPPWQSAD
| |  |. || .| | || .| |
DIWAAGVILYILLCGFPPFRSPD
Kinase CG11221.AA Pkinase 287-305 32 0.528333 4.63 Pfam 198-222 (293) Show / Hide 
Range on Protein: 287-305
Range on HMM: 198-222/293
Sequence Identity: 32% (8 aa)

FGILLYNILTGNPPWQSA------D
.|..||  |.|.||....      |
CGCILYEMLCGRPPFPGHCWHDNHD