Gene wit (Fruit Fly)

wit

Species: Fruit Fly
Alias: ALK3/BMPRII, SE20, 1262/15, wishful thinking, SFO084, CG10776, Serine/threonine kinase-D, wit, l(3)S126215, l(3)SH12, STK-D, l(3)64Aa, Stk-D
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 64A5

Classification

Group: TKL
Family: STKR
Subfamily: STKR2

Sequence

Name Sequence Type Origin Length Description Download
wit.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 296 Kinase domain by global Sugen HMM Fasta, JSON
wit.AA Protein Various 903 None Fasta, JSON

Protein domain

Protein domains of wit.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase wit.AA Type2 224-525 46 1.3e-204 681.74 In-house 1-315 (315) Show / Hide 
Range on Protein: 224-525
Range on HMM: 1-315/315
Sequence Identity: 46% (147 aa)

MNLIGMLGSGKYGTVMKGLLHDQ-----EVAVKIYPEEHHQYYVNERNIYALP-LMECPALLSYFGYDER--CTMDGRMEYQLVLSLAPLGCLQDWLIAN
..|....|.|..|.|.|. .|..     .|||||.||...|...||..||.|| .|.....|.......|  ...||.|||.||..... |.|.|.|...
IQLMELIGKGRFGCVWKAQWHNNNGEKRTVAVKIFPEQDKQSWQNEKDIYSLPYHMWHENILQFICAEKRRVHMGDGWMEYWLVTEFHHKGSLCDYLKQH

TLTFSECCGMLRSITRGISHLHTELRLGDQ---HKPCVAHRDINTRNVLVQADLSCCIADFGFALKVFGSKYEYKGEVAM-AETKSINEVGTLRYMAPEL
|....|||.|..|..||..|||.|.....|   |||..|||||...||||..|..|||||||.|......|..||.|..| ..|..|..||| ||||||.
TIDWHECCRMAMSMARGLAHLHEEIWQWCQTDHHKPPIAHRDIKSKNVLVKNDMTCCIADFGLAMRFCPGKQPYKWEPTMPGDTHNIGQVGTRRYMAPEV

LEGAVNLRDCETSLKQMDVYALGLVLWEVATRCSDFYAPGQATPPYKAPYEQEVGSH-PSFDQMQALVVRHKARPLFPTGWG-GGAAAKVVRDTCEDCWD
||||||..||....||||.||.||||||...||.|.|. ....|.|..|.|.|||.| |||..||.||||...|| .|..|. ..........|.|||||
LEGAVNFQDCRDAFKQMDMYAMGLVLWEMVSRCTDHYP-DDEVPEYQMPFEEEVGQHDPSFEDMQELVVRKRKRPQWPDHWKCHPGMQRMLCETIEDCWD

HDADARLTSLCAEERM
|||.||||..|..|||
HDAEARLTAQCVQERM
Kinase wit.AA STKR 224-525 39 1e-179 585.15 In-house 1-312 (312) Show / Hide 
Range on Protein: 224-525
Range on HMM: 1-312/312
Sequence Identity: 39% (122 aa)

MNLIGMLGSGKYGTVMKGLLHD----QEVAVKIYPEEHHQYYVNERNIYALPLMECPALLSYFGYDERCTMDGRMEYQLVLSLAPLGCLQDWLIANTLTF
..||.. |.|.||.|.|| ...    ..|||||.|....|.. .|..|| .|.|... .|.....|...|......|.|.. . ..|.|.|.| ..|...
IQLIECIGKGRYGEVWKGKWRGNGEKETVAVKIFPSRDEQSWFRETEIYQTPMMRHENILQFIAADMKHTEGSWTQYWLITEYHENGSLCDYLKRHTIDW

SECCGMLRSITRGISHLHTELR--LGDQ-HKPCVAHRDINTRNVLVQADLSCCIADFGFALKVFGSKYEYKGEVAMAETKSINEVGTLRYMAPELLEGAV
 |.|.| .|...|..|||.|.    ..| |||..|||||...|.||..|..|||||||.|... ...........|........||| ||||||.|.||.
HEMCRMAHSMACGLAHLHMEIWGWGTQQHHKPAIAHRDIKSKNILVKNDGTCCIADFGLAMRHDPDTNQIDIHNTMQDNAQNTQVGTKRYMAPEVLDGAM

NLRDCETSLKQMDVYALGLVLWEVATRCSDFYAP--GQATPPYKAPYEQEVGSHPSFDQMQALVVRHKARPLFPTGWG-GGAAAKVVRDTCEDCWDHDAD
|....|...|.||.||.|||.||.|.||.|....  .| .|.|. |....|..||||..||..|.|.. || .|. |    .| .....|.|.|||||..
NFQCFESAFKRMDMYAMGLVMWEIARRCTDGGPDLVDQIVPEYQMPFYDWVPNHPSFEDMQKVVCRKRQRPNIPNRWKCNHPAMRSMCKTMEECWDHDPE

ARLTSLCAEERM
||||.|| ...|
ARLTALCVKKTM
Kinase wit.AA Type1 224-525 30 1.7e-85 231.37 In-house 1-290 (290) Show / Hide 
Range on Protein: 224-525
Range on HMM: 1-290/290
Sequence Identity: 30% (93 aa)

MNLIGMLGSGKYGTVMKGLLHDQEVAVKIYPEEHHQYYVNERNIYALPLMECPALLSYFGYDERCTMDGRMEYQLVLSLAPLGCLQDWLIANTLTFSECC
 ..|   |.|.|| | .|  .. .|||||.     . . .|. ||   .|  .  |.... | . . .   .  |.    ..| | |.|  .||.  ...
IQMIECIGKGRYGEVWRGKWRGENVAVKIFFSRDERSWFRETEIYQTVMMRHENILGFIAADMKDN-GSWTQLWLITDYHEHGSLYDYLNRHTLDTQQML

GMLRSITRGISHLHTELRLGDQ--HKPCVAHRDINTRNVLVQADLSCCIADFGFALKVFGSKYEYKGEVAMAETKSINEVGTLRYMAPELLEGAVNLRDC
 . .|.  |. |||.|   | |   || .||||| ..|..|  ...|||||.| |..    . . . .. ....   . ||| ||||||.|.   | .. 
RLAYSCACGLAHLHMEI-FGTQEFGKPAIAHRDIKSKNIMVKKNGQCCIADLGLAVR----HQQDTDQIDIGQN---PRVGTKRYMAPEVLDETMNMNCF

ETSLKQMDVYALGLVLWEVATRCSDFYAPGQATPPYKAPYEQEVGSHPSFDQMQALVVRHKARPLFPTGWGGGAAAKVVRDTCEDCWDHDADARLTSLCA
| | |  |.|..|||.||.| ||...         |. ||   | . |||..|.. |   | || .|  |    . ...    ..|| . ..||.|.|  
E-SYKMADIYSFGLVMWEIARRCEVGG----IVEDYQLPYYDWVPNDPSFEDMRKVVCVRKLRPNIPNRWQSHPCMRHMAKLMKECWYQNPHARHTALRI

EERM
   .
KKTL
Kinase wit.AA TKL 230-525 21 2.3e-78 266.67 In-house 1-364 (364) Show / Hide 
Range on Protein: 230-525
Range on HMM: 1-364/364
Sequence Identity: 21% (83 aa)

LGSGKYGTVMKGLLHD----------QEVAVKIYPEEH-------------------------HQYYVNERNIYALPLME---CPALLSYFGYDERCTM-
.||| .|.| || ..           ..||||......                         ..   ... .. . .|    .| .... ||. ...  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-------DGRMEYQLVLSLAPLGCLQDWLIANTLTFSECCGMLRSITRGISHLHTEL----RLGDQHKPCVAHRDINTRNVLVQADLS------------
       .. ... .|  ..| |.| . |.     ..  | . ..| ||...||..     .     || ..|||....|.||  ..             
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCT-----KPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

--CCIADFGFALKVFGSKYEYKGEVAMAE--------TKSINEVGTLRYMAPELLEGAVNLRDC---------ETSLKQMDVYALGLVLWEVATRCSDFY
  |.|.|||..  ...|.   ... .| |        .......||.|.||||.|.|. |....         ..  ...|||. |.||||..|||    
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR---

APGQATPPYK-APYEQEVGSHPSFDQMQALVVRHKARPLFPTGWGG-------GAAAKVVRDTCEDCWDHDADARLTSLCAEERM
       ||.  ||.......| |..|...|. .. ||. |. |           . . ... ..||||||...|.. ..  .|.
-------PYYDYPYMPMIFQDP-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase wit.AA Pkinase 224-528 17 9e-25 88.67 Pfam 1-293 (293) Show / Hide 
Range on Protein: 224-528
Range on HMM: 1-293/293
Sequence Identity: 17% (60 aa)

MNLIGMLGSGKYGTVMKGLLHDQE--VAVKIYPEEHHQYYVNER-----NIYALPLMECPALLSYFGYDERCTMDGRMEYQLVLSLAPLG----CLQDWL
  ... .||| .|.| |.  .. .  ||||| . .|    ....      |. .  . .|  . .... |.     . .. .|. ... |     | |..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-----KDHIYMVMEYCEGGLYVMDLFDYI

I---ANTL--TFSECCGMLRSITRGISHLHTELRLGDQHKPCVAHRDINTRNVLVQADLSC----CIADFGFALKVFGSKYEYKGEVAMAETKSINEVGT
     ...  .  ||. ... | ||. ..| .          . |||.   |.|.  .  .    .|.|||.| ..               .     .||
STWRHGCFYFSEWECKFYMYQILRGLEYCHSM---------GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----------Y-NNS-MTTFCGT

LRYMAPELLEGAVNLRDCETSLKQMDVYALGLVLWEVATRCSDFYAPGQATPPYKAPYEQEVGSHPSFDQMQALVVRHKARPLFPTGW------------
..|||||.      .|...   .  |....|..|.|....                |. ...  |.. . ......| . .||    .            
PWYMAPEV------IRGGQYYGPKVDMWSCGCILYEMLCGR--------------PPFPGHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRH

------GGGAAAKVVRDTCEDCWDHDADARLTSLCAEERMQE--M
         .. .  .| ...|.. |   |.|   ||. .|   .
WHFHWTF-HNWSEECKDFIKWCLCKDPKKRPT---AEQILQHPWF
Kinase wit.AA TK 224-451 14 7.5e-19 59.11 In-house 1-398 (486) Show / Hide 
Range on Protein: 224-451
Range on HMM: 1-398/486
Sequence Identity: 14% (58 aa)

MNLIGMLGSGKYG---TVMKGLLHD---------------------------QEVAVKIYPEEHHQYYVNERN----------------IYALPLME---
  |.  ||.| .|   .|.||....                           ..||||.  |....    ..                   .  ...   
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-CPALLSYFGYDERCTMDGRME-------YQLVLSLAPLGC----LQDWLIANTLTFSECCG--------------------------------------
 .| ... .|.  .     . |       . .|. ..|.|.    |.|.| ..  .|.. .                                       
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

--------------------------------------MLRSITRGISHLHTE---LRLGDQHKPCVAHRDINTRNVLVQADLS-----------CCIAD
                                      | . | .| ..||     .       . . |||. .||.||  ..            | |||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEF------IQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIAD

FG--------FALKVFGSKYEYKGE---------------VAMAETKSINEVGTLRYMAPELLEGAVNLRD--CETSLKQMDVYALGLVLWEVATRCSDF
||         | ..  ... |. .                     .. .    .|.|||| |.. |  .     .   . ||...| ..||. |..   
FGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEP

YAPG
|..|
YYGG
Kinase wit.AA S_TKc 224-529 14 9.2e-16 54.25 SMART 1-231 (231) Show / Hide 
Range on Protein: 224-529
Range on HMM: 1-231/231
Sequence Identity: 14% (47 aa)

MNLIGMLGSGKYGTVMKGLLHD--QEVAVKIYPEEHHQYYVNERNIYALPLMECPALLSYFGYDERCTMDGRMEYQLVLSLAPL--GCLQDWLIANT---
  ..  .|.| .|.|.|.  ..  ..||.|| .    .   .|..|       .| .  .... .        .. .|. ...   | | | .  .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK---HHPNIVKLYDVFQD------DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LTFSECCGMLRSITRGISHLHTELRLGDQHKPCVAHRDINTRNVLVQADLSCCIADFGFALKVFGSKYEYKGEVAMAETKSINEVGTLRYMAPELL
    ..  ... ... | ... ..|         .  . |||.   |.|.       |.|||.| ..                     .||. |||||.|
LRFPFPE-HARFYMYQICCALEYCH--------SH-GIIHRDLKPENILLDE--HIKICDFGLARQL------------------TTFCGTPWYMAPEVL

EGAVNLRDCETSLKQMDVYALGLVLWEVATRCSDFYAPGQATPPYKAPYEQEVGSHPSFDQMQALVVRHKARPLFPTGWGGGAAAKVVRDTCEDCWDHDA
           . .  |....| .|.| ....  |.        ... ... .                                . ..|  . |.. | 
---------GYGKCKCDWWSCGCILYEMLCGYPPFP-------QMQMMFKKIG-------------------------------SPEAKDFIRKCLQKDP

DARLTSLCAEE-----RMQEMS
. |.|   | .     .. .  
EKRPTA-EALQDEWDIKCHPWF
Kinase wit.AA TyrKc 224-525 22 2.1e-14 10.21 SMART 1-280 (280) Show / Hide 
Range on Protein: 224-525
Range on HMM: 1-280/280
Sequence Identity: 22% (71 aa)

MNLIGMLGSGKYGTVMKGLLHDQEVAVKIYPEEHHQYYVNERNIYALPLM--ECPALLSYFGYDERCTMDGR-----MEYQLVLSLAPLGCLQDWLIANT
  |. .||.| .|.|.|| .  ..||||   |....   .|  .  .     . | ..  .|.   || .||       . .|. ..|.|.|.| | .. 
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDAREDFMRE--ARIMCKLGGHHPNIVRLYGV---CTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

--LTFSECCGMLRSITRGISHLHTELRLGDQHKPCVAHRDINTRNVLVQADLSCCIADFGFALKVFGS---KYEYKGEVAMAETKSINEVGTLRYMAPEL
  |. .. . .   | .| ..||           .. |||. .||.|| ... . |.||| . ..        | |    ..|.|. . .  .| |||| 
PKLCMKDLLSFCWQIACGMEYLHSK---------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG-ESKDYYRKKEHKGGKTMLPIRWMAPEC

LEGAVNLRDCETSLKQMDVYALGLVLWEVATRCSDFYAPGQATPPYKAPYEQEVGSHPSFDQMQALVVRHKARPLFPTGWGGGA----AAKVVRDTCEDC
.      .... . |  ||.. | ..||. |..          .||  . .|      | ... ..| . . .|  | .         . . . .  ..|
I------NYGKFTTK-SDVWSFGVCMWEIFTYGQ---------QPYPGMIQQ----MMSNQEVIEYVKQGYRMPQPPNDY-P-MSFVCCPDEMYQIMKQC

WDHDADARLTSLCAEERM
|..|.. | |     |..
WHEDPEDRPTFSEIHECF
Kinase wit.AA C8 346-437 29 1.7e-13 43.28 In-house 140-226 (226) Show / Hide 
Range on Protein: 346-437
Range on HMM: 140-226/226
Sequence Identity: 29% (28 aa)

HKPCVAHRDINTRNVLVQADLSCC----IADFGFALKVFGSKYEYKGEVAMAETKSINEVGTLRYMAPELLEGAVNLRDCETSLKQMDVYALGLVL
|   . ||||   | ||..| .      ..||||| .|  .| ..     ..       .||. |.||| ...  .  .   . .| |.. .||||
HCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNT-------CGTWAYFAPEIEKK--QDNQYKQYRIQSDLFSVGLVL
Kinase wit.AA TKL-Unique 347-444 29 7.3e-11 34.71 In-house 131-225 (290) Show / Hide 
Range on Protein: 347-444
Range on HMM: 131-225/290
Sequence Identity: 29% (30 aa)

KPCVAHRDINTRNVLVQAD-----LSCCIADFGFALKVFGSKYEYKGEVAMAETKSINEVGTLRYMAPELLEGAVNLRDCETSLKQMDVYALGLVLWEVA
.| ..|||. ..|.||  .     ..  |.|||..     .  . ..|          ..|..|.||||.|..  .....     . |||. | |||| |
PP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTR--NQTRCGSFRWMAPEVLRMNFCQYSE-----KSDVYSFGIVLWEIA

TRC
||.
TRK
Kinase wit.AA Ciliate-E2 346-414 22 1.5e-08 25.48 In-house 177-261 (365) Show / Hide 
Range on Protein: 346-414
Range on HMM: 177-261/365
Sequence Identity: 22% (21 aa)

HKPC-VAHRDINTRNVLVQADLSCCIADFGFALKVFGSKYEYKGEVAMAETKSINE----------------------VGTLRYMAPELLEG
|.   . ||||   |.|.     ..|.|||.. |.  . ... .   ... .                          .||. ||||| |.|
HSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNG
Kinase wit.AA MOS 224-252 37 7.8e-08 21.83 In-house 1-29 (299) Show / Hide 
Range on Protein: 224-252
Range on HMM: 1-29/299
Sequence Identity: 37% (11 aa)

MNLIGMLGSGKYGTVMKGLLHDQEVAVKI
  | .|.|.| .|.| |.  ..  ||||.
VCLCQMIGRGGFGSVWKAQYCGRPVAVKQ
Kinase wit.AA CAMK 285-414 18 2.7e-07 18.79 In-house 109-294 (425) Show / Hide 
Range on Protein: 285-414
Range on HMM: 109-294/425
Sequence Identity: 18% (37 aa)

DERC--------TMDG-----RMEYQLVL---SLAPLGCL----QDWLIAN----------------TLTFSECCGMLRSITRGISHLHTELRLGDQHKP
|...        | .      .... .|.    ... |.|     |.....                 .| .|.. . | |  .. ..|           
DPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSH---------

CVAHRDINTRNVLVQAD-----------------LSCCIADFGFALKVFGSKYE-----YKGEVAMAET---------KSINEVGTLRYMA-PELLEG
 ..|||.   |.|.. .                     |.||||| |..... .     |||.  | ..         |    .||. ||| ||.|.|
NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HNQWTTPTEGQKMKTFCGTPEYMAAPEVLNG
Kinase wit.AA Pkinase_Tyr 224-259 28 9e-06 20.15 Pfam 1-42 (270) Show / Hide 
Range on Protein: 224-259
Range on HMM: 1-42/270
Sequence Identity: 28% (12 aa)

MNLIGMLGSGKYGTVMKGLLH------DQEVAVKIYPEEHHQ
  .. .||.| .|.|.|| ..      ...||||. .| ...
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMH
Kinase wit.AA MOS 368-443 34 1.3e-05 14.34 In-house 170-234 (299) Show / Hide 
Range on Protein: 368-443
Range on HMM: 170-234/299
Sequence Identity: 34% (26 aa)

CCIADFGFALKVFGSKYEYKGEVAMAETKSINEVGTLRYMAPELLEGAVNLRDCETSLKQMDVYALGLVLWEVATR
| . |||   ..|.|     |    | | .    ||..||||||| |       .|     |.| .|  .|   ||
CKLCDFGCSQQMFDS----NGKEFCAWTNPHYLKGTCTYMAPELLCG-------DTPTPKADIYSFGITMWQMQTR
Kinase wit.AA Pkinase_Tyr 352-374 47 7.9e-05 16.98 Pfam 134-156 (270) Show / Hide 
Range on Protein: 352-374
Range on HMM: 134-156/270
Sequence Identity: 47% (11 aa)

HRDINTRNVLVQADLSCCIADFG
|||. .||.||  .. . |.|||
HRDLAARNCLVTENNVVKICDFG
Kinase wit.AA CAMK 229-254 25 0.000119 10.12 In-house 1-40 (425) Show / Hide 
Range on Protein: 229-254
Range on HMM: 1-40/425
Sequence Identity: 25% (10 aa)

MLGSGKYGTVMKGLLH-D-------------QEVAVKIYP
 ||.| .|.| ..    .             |.||.||..
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIID
Kinase wit.AA TKL-Unique 226-252 37 0.000511 10.27 In-house 1-27 (290) Show / Hide 
Range on Protein: 226-252
Range on HMM: 1-27/290
Sequence Identity: 37% (10 aa)

LIGMLGSGKYGTVMKGLLHDQEVAVKI
 .  .|.|.||.| ||  .  .||.|.
FWNKIGEGGYGQVYKGKWRGYPVAIKQ
Kinase wit.AA Ciliate-E2 224-253 20 0.007402 5.62 In-house 1-50 (365) Show / Hide 
Range on Protein: 224-253
Range on HMM: 1-50/365
Sequence Identity: 20% (10 aa)

MNLIGMLGSGKYGTVMKG--LLHDQ------------------EVAVKIY
 ..| ..|.| .|.| |.   . ..                  .|..|||
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIY
Kinase wit.AA Pkinase_Tyr 429-444 37 1.715384 2.29 Pfam 196-211 (270) Show / Hide 
Range on Protein: 429-444
Range on HMM: 196-211/270
Sequence Identity: 37% (6 aa)

DVYALGLVLWEVATRC
||.. | ..||. |..
DVWSFGVLMWEIFTYG