Gene wee (Fruit Fly)

wee

Species: Fruit Fly
Alias: wee, Wee, CG4488, Dwee, SFO094, Wee1, WEE1, wee1, Dwee1
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 27C4,

Classification

Group: Other
Family: WEE
Subfamily: WEE1

Sequence

Name Sequence Type Origin Length Description Download
wee.AA Protein Various 609 None Fasta, JSON
wee.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 279 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of wee.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase wee.AA WEE 239-517 45 3.6e-165 555.0 In-house 1-297 (297) Show / Hide 
Range on Protein: 239-517
Range on HMM: 1-297/297
Sequence Identity: 45% (141 aa)

FMQVNVIGVGEFGVVFQCVNRLDGCIYAIKKSKKPVAGSSFEKRALNEVWAHAVLG------KHDNVVRYYSAWAEDDHMLIQNEFCDGGS--LHARIQD
|..|..||.|.|| |..|..|.|||||||||||.|..|.|..||||.||.||.|||      .|...|||||||.|||||.||.|.|.|||  |...||.
FQEVQKIGEGSFGEVYKCRCRIDGCIYAIKKSKQPFRGYSERKRALREVYAHMVLGQIMDCDHHPHIVRYYSAWEEDDHMYIQMEYCNGGSNLLQFWIQQ

-----HCLGEAELKIVLMHVIEGLRYIHSN-DLVHMDLKPENIFSTMNPNAHKLVEVQPQQTKDDDGMDSVYEELRHSENLVTYKIGDLGHVTSVK----
     |.| |.... .|.....||..|||| ..||||.|||||| ... |....| ...||...|.          . .| ...||||.||||...    
CHNWNHWLPEWMIWQILVDICQGLHHIHSNCGMVHMDIKPENIFISKKMNCNQIV-NNDQQNNNDW----------W-FN-MMCKIGDFGHVTDMNSNNN

EPYVE-EGDCRYLPKEILHE--DYSNLFKADIFSLGITLFEAAGGGPLPKNGPEWHNLRDG-------KVP---ILPSLSRDFNELIAQMMHPYPDKRPT
.|..| |||.||...|||..  .|..|.||||||||||..|.|.. .|||||..||..| |       . |   .. ..|.....||..||||.|..|||
NPHQEQEGDSRYMAPEILQGYYHYTHLYKADIFSLGITIYELACNMDLPKNGDWWHQIRQGDLSFDKNQIPFPEFDNIISQELKQLIKWMMHPDPEQRPT

SQSIFSHPIL
.|....||.|
CQQLLQHPVL
Kinase wee.AA Pkinase 239-517 22 1.3e-48 172.56 Pfam 1-293 (293) Show / Hide 
Range on Protein: 239-517
Range on HMM: 1-293/293
Sequence Identity: 22% (73 aa)

FMQVNVIGVGEFGVVFQCVNRLDGCIYAIKKSKKPVAGSSFEKRALN--EVWAHAVLGKHDNVVRYYSAWAEDDHMLIQNEFCDGG----SLHARIQ---
.  . .|| | ||.|..|... .|.|.|.|. ||. . |........  |.  .. | .|.|.||.| .. ..||. .  |.|.||    .|...|.   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

DHCL--GEAELKIVLMHVIEGLRYIHSNDLVHMDLKPENIFSTMNPNAHKLVEVQPQQTKDDDGMDSVYEELRHSENLVTYKIGDLGH-----VTSVKEP
. |.   | |.| ..  ...|| |.||.  .| |||||||.   |..                                . ||.| |        .   .
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA-----------------------------CVKICDFGLAKQFDY-NNS-M

YVEEGDCRYLPKEILHEDYSNLFKADIFSLGITLFEAAGGGPLPKNG-------PEWHNLRDGKVPILPSLS-----------------------RDFNE
..  |  .|.. |.. ..     |.|..|.|..|.| . | |. ..        . .   |... |.  . .                       ... .
TTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKD

LIAQMMHPYPDKRPTSQSIFSHPIL
.|  . .. | |||| . |. || .
FIKWCLCKDPKKRPTAEQILQHPWF
Kinase wee.AA S_TKc 239-517 21 1.2e-31 112.35 SMART 1-231 (231) Show / Hide 
Range on Protein: 239-517
Range on HMM: 1-231/231
Sequence Identity: 21% (65 aa)

FMQVNVIGVGEFGVVFQCVNRLDGCIYAIKKSKKPVAGSSFEKRALNEVWAHAVLGKHDNVVRYYSAWAEDDHMLIQNEFCDG--GSLHARIQDHC----
.  ...|| | ||.|..|... .| |.|||. |         .....|.  .    .|.|.|..| .. . ||. .  |.|||  |.|. .|...     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LGEAELKIVLMHVIEGLRYIHSNDLVHMDLKPENIFSTMNPNAHKLVEVQPQQTKDDDGMDSVYEELRHSENLVTYKIGDLGHVTSVKEPYVEEGDC
   . | . . ..  ....| |.||.  .| |||||||. .                                    . ||.| |  . .         |
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----------------------------------HIKICDFGLARQL------TTFC

---RYLPKEILHEDYSNLF-KADIFSLGITLFEAAGGGPLPKNGPEWHNLRDGKVPILPSLSRDFNELIAQMMHPYPDKRPTSQSIFS-------HPIL
    |.. |.|    .  . |.|. |.|..|.| . | |.     . . . .  .      |... ..| ....  |.||||   ..        || .
GTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase wee.AA Ciliate-E2 239-517 17 6.8e-29 96.3 In-house 1-365 (365) Show / Hide 
Range on Protein: 239-517
Range on HMM: 1-365/365
Sequence Identity: 17% (70 aa)

FMQVNVIGVGEFGVVFQCVNRLDGCIYAIK--------------KSKKPVAGSSFEKRALNEVWA--HAV-----------------LGKHDNVVRYYSA
.  ...|| | ||.|..| ...... .|||                .| .|  ...|. ....    |                   . .|.|....| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

WA--EDDHMLIQNEFCDGGSLHARIQDH------------CLGEAELKIVLMHVIE---------------GLRYIHSND-LVHMDLKPENIFSTMNPNA
.    |... .  |.|.||.|  .|...            .. | | | .  ....               .|.|.||.   .| |.|||||.       
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

HKLVEVQPQQTKDDDGMDSVYEELRHSENLVTYKIGDLGHVTSVKEPYVEE-----------------------------------GDCRYLPKEILH-E
                                 || |.|  . ..... ..                                   |   |.. |||  .
--------------------------------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGK

DYS-------NLFKADIFSLGITLFEAAGGGPLPKNGPEWHNLRDGKVP------------------ILPSLSRDFNELIAQ----MMHPYPDKRPT-SQ
.|.         .|.||.|||..|.|   | |         .  ..|.                   .  ..| .   || .    |.   |.||.|  .
KYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF-----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWE

SIFSHPIL
 |. ||..
QILNHPWF
Kinase wee.AA CAMK 244-367 19 1.2e-25 78.97 In-house 1-210 (425) Show / Hide 
Range on Protein: 244-367
Range on HMM: 1-210/425
Sequence Identity: 19% (40 aa)

VIGVGEFGVVFQCVNRLDG------------CIYAIKKSKKPVAGSSF--------------------------EKRALNEVWAHAVLGK------HDNV
..| | ||.|. |......              .|||  .|  . ..                           .|. ..|.  .  | .      | |.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRYYSAWAE-------------------DDHMLIQN---EFCDGG----SLHARIQDH----------------CLGEAELKIVLMHVIEGLRYIHSNDL
.. | ..                     |.|| .     |.|.||     |  .|..|                .. |.| . .   ......|.||.. 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHMDLKPENI
|| |||||||
VHRDLKPENI
Kinase wee.AA STE 240-368 22 1.8e-21 72.63 In-house 1-184 (359) Show / Hide 
Range on Protein: 240-368
Range on HMM: 1-184/359
Sequence Identity: 22% (41 aa)

MQV-NVIGVGEFGVVFQCVNRL---------------DGCIYAIKKSKKPVAGS---------------SFEKRALNEVWAHAVLGK-HDNVVRYYSAWA
 .   .|| | ||.|....|.                 |.|.|||. ..    .               . ... |.|.  .  . . |.|.|.|| .  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

ED-------DHMLIQNEFCDGGSLHARIQD--HCLG-------------EAELKIVLMHVIEG-LRYIHSNDLVHMDLKPENIF
 .       |.  |  |..|||||   |.    |..             | ......  ...| | |.||.  .| |.|| ||.
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANIL
Kinase wee.AA PEK 239-311 32 2.3e-17 56.34 In-house 1-88 (655) Show / Hide 
Range on Protein: 239-311
Range on HMM: 1-88/655
Sequence Identity: 32% (29 aa)

FMQVNVIGVGEF-GVVFQCVNRLDGCIYAIKKSKKPVAG---------------SSFEKRALNEVWAHAVLGKHDNVVRYYSAWAEDDH
| .. ..| |.| |.|... |.|||| ||||. | . ..               .. ....| || . | |  | |.|||..|| |...
FEEIQCLGKGGFGGQVYKVQNKLDGCYYAIKRIKLNWKQRKQPCITQECMIHKCKKHCEKVLREVKTLARL-NHPNIVRYHNAWIEKPE
Kinase wee.AA Ciliate-E2-Unclassified 239-368 18 3.1e-17 56.33 In-house 1-176 (352) Show / Hide 
Range on Protein: 239-368
Range on HMM: 1-176/352
Sequence Identity: 18% (33 aa)

FMQVNVIGVGEFGVVFQCVNRLDG--------CIYAIKKSKKPVAGSSFEKRALNEVWAHA-------------VLGKHDNVVRYYSAWAE--DDHMLIQ
.  . .|| | ||.|..|... ..        . . |.|.|.       ... ..|.  .               |  |.. ....  ...  .... | 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

NEFCDGGSLHARIQD------------------HCLGEAELK-----IVLMHVIEGLRYIHSND-LVHMDLKPENIF
 |.|.||.|.  |..                  ... | . |       . ....|| |.|..   .| |.|||||.
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENIL
Kinase wee.AA SLK 239-372 28 1.7e-15 48.67 In-house 1-133 (259) Show / Hide 
Range on Protein: 239-372
Range on HMM: 1-133/259
Sequence Identity: 28% (39 aa)

FMQVNVIGVGEFGVVFQCVNRLDGCIYAIKKSKKPVAGSSFEKRALNEVWAHAVLGKHDNVVRYYSAWAEDDHMLIQNEFCDGGSLHARI--QDHCLGEA
.  .  .| | || | . ... .  ..|  |. .   .   |   . |.   . .  | |.|. |.|.  |... .  |||||| . . .   .| | | 
WEIIGELGDGAFGKVYKAQHK-EQKVFAAAKMIEIKDEEELED-YMVEIDILSECK-HPNIVKLYEAYYYDNKLWMMIEFCDGGAVDNIMVELEHPLTED

ELKIVLMHVIEGLRYIHSNDLVHMDLKPENIFSTMN
 ...|  |..|.|...||| ..| |||  ||  ||.
QIQYVCKHMCEALNWLHSNKVIHRDLKAGNILMTMD
Kinase wee.AA PEK 239-313 35 6.4e-13 38.27 In-house 1-81 (758) Show / Hide 
Range on Protein: 239-313
Range on HMM: 1-81/758
Sequence Identity: 35% (29 aa)

FMQVNVIGVGEFGVVFQCVNRLDGCIYAIKKSKKPV-------AGSSFEKRALNEVWAHAVLGKHDNVVRYYSAWAEDDHML
|  . ..| | |||||.  | .|.. ||||.   |          .|.  . . || . | |  | | |||..|| | . .|
FEHIQCLGHGGFGVVFRAKNKVDMNNYAIKRITFPNSNNQSPTNRESAREKVMREVRTLAML-DHHNIVRYFNAWLETPELL
Kinase wee.AA GCN2 314-368 45 2.4e-12 39.13 In-house 284-340 (511) Show / Hide 
Range on Protein: 314-368
Range on HMM: 284-340/511
Sequence Identity: 45% (26 aa)

IQNEFCDGGSLHARIQDH--CLGEAELKIVLMHVIEGLRYIHSNDLVHMDLKPENIF
|| |.|.|..|   | .|  |. ..||. ..  ..||| ||||.  .| |||| |||
IQMEYCEGKTLRQYIDNHGWCMDHDELWRYFRQILEGLNYIHSQGMIHRDLKPSNIF
Kinase wee.AA TyrKc 239-517 17 3.2e-12 -25.03 SMART 1-280 (280) Show / Hide 
Range on Protein: 239-517
Range on HMM: 1-280/280
Sequence Identity: 17% (58 aa)

FMQVNVIGVGEFGVVFQCVNRLDGCIYAIKKSKKPVAGSSFEKRALNEVWAHAVLG-KHDNVVRYYSAWAED-------DHMLIQNEFCDGGSLHARIQD
     ..| |.||.|.... .      |.|. |.       ..  ..|      || .|.|.|| | .  ..       . ..|  |....|.|. ....
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

HC--LGEAELKIVLMHVIEGLRYIHSNDLVHMDLKPENIFSTMNPNAHKLVEVQPQQTKDDDGMDSVYEELRHSENLVTYKIGDLG---HVTSV------
|   |  ..|      . .| .|.||. ..| ||   |.  . |                                  | ||.| |    ...       
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---------------------------------TVKISDFGLSRDIYDDDQQGES

KEPYVEEG--DCR------YLPKEILHED-YSNLFKADIFSLGITLFEAAGGGPLPKNG-----PEW----HNLRDGKVPILPSL---------SRDFNE
|. |.  .  ...       .. | . .  ..  .| |..| |....|    |  |  |      ..    .....|. .  |           . .  .
KDYYRKKEHKGGKTMLPIRWMAPECINYGKFT--TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ

LIAQMMHPYPDKRPTSQSIFSHPIL
.. |  |  |..||| . |  | ..
IMKQCWHEDPEDRPTFSEI--HECF
Kinase wee.AA GCN2 239-313 35 1.2e-11 36.6 In-house 1-79 (511) Show / Hide 
Range on Protein: 239-313
Range on HMM: 1-79/511
Sequence Identity: 35% (28 aa)

FMQVNVIGVGEFGVVFQ-CVNRLDGCIYAIKKSKKPVAGSSFEKR--ALNEVWAHAVLGKHDNVVRYYSAWAE--DDHML
|  . ..| |.|| |     |..||..||||| . . .. . ...   . ||   . |  | .||||| ||.|  |. |.
FEEICCLGKGGFGQVVKNVRNMHDGRYYAIKKWPINWKQRKLPCKHKIMREVKLLCRL-HHQHVVRYYQAWIEKCDEPMV
Kinase wee.AA STE 445-517 22 1.2e-10 33.89 In-house 247-359 (359) Show / Hide 
Range on Protein: 445-517
Range on HMM: 247-359/359
Sequence Identity: 22% (25 aa)

FKADIFSLGITLFEAAGGGPL----PKNGPEWHNLRD--------------GKVPILPS--------------------LSRDFNELIAQMMHPYPDKRP
.|.|| |||.|. | | | |     .     .. ..               |. | ||.                    .| .|.. |..     |.|||
TKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRP

TSQSIFS--HPIL
|..   .  || .
TASQLLKSEHPFI
Kinase wee.AA NEK 295-368 27 5.8e-10 31.67 In-house 62-151 (286) Show / Hide 
Range on Protein: 295-368
Range on HMM: 62-151/286
Sequence Identity: 27% (25 aa)

KHDNVVRYYSAWAEDD--HMLIQNEFCD-GGSLHAR---IQDH-----CLGEAELKIVLMHVIEGLRYIHSN-----DLVHMDLKPENIF
||.|.|.|| .. |..  .. |  |.|. || |. .   |. .      . | .   .. . . .|.|.|..       .| |.|| |||
KHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKSIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIF
Kinase wee.AA PEK 314-368 21 1.1e-09 29.07 In-house 360-459 (655) Show / Hide 
Range on Protein: 314-368
Range on HMM: 360-459/655
Sequence Identity: 21% (21 aa)

IQNEFCDGGSLHARIQDHC---------------------------------------------LGEAELKIVLMHVIEGLRYIHSNDLVHMDLKPENIF
|| |.|....|   |....                                             . . ...  .  ..||| ||||. ..| |||| |||
IQMEYCEKKTLRDWIDNNGCPVQFNYWRRNSCKNHYNNYIMNQCCFQSTWSMNMRQWDENNCMFWDKDQCWRIFRQILEGLNYIHSQGMIHRDLKPSNIF
Kinase wee.AA PEK 492-517 46 7.4e-07 17.63 In-house 733-758 (758) Show / Hide 
Range on Protein: 492-517
Range on HMM: 733-758/758
Sequence Identity: 46% (12 aa)

ELIAQMMHPYPDKRPTSQSIFSHPIL
|.| |||.. || |||.  | .|.. 
EFIQQMMSMNPDERPTADQISMHDFF
Kinase wee.AA PEK 474-517 25 8.1e-07 18.95 In-house 604-655 (655) Show / Hide 
Range on Protein: 474-517
Range on HMM: 604-655/655
Sequence Identity: 25% (13 aa)

NLRD------GKVP--ILPSLSRDFNELIAQMMHPYPDKRPTSQSIFSHPIL
.|||      |. |  .. .  ... ..| .|... |..||..| | .|. .
DLRDESIQFPGDFPPKWFDNKYPKQADFIQWMLSHDPQQRPSAQQILQHEFF
Kinase wee.AA PEK 346-368 60 1.2e-05 13.46 In-house 452-474 (758) Show / Hide 
Range on Protein: 346-368
Range on HMM: 452-474/758
Sequence Identity: 60% (14 aa)

IEGLRYIHSNDLVHMDLKPENIF
.||..||||  . | |||| |||
CEGVNYIHSKGMIHRDLKPSNIF
Kinase wee.AA NEK 478-517 34 1.3e-05 16.22 In-house 243-286 (286) Show / Hide 
Range on Protein: 478-517
Range on HMM: 243-286/286
Sequence Identity: 34% (15 aa)

G-KVPILPSL---SRDFNELIAQMMHPYPDKRPTSQSIFSHPIL
| . | .||    |.| ..|| || .. |..||. ..|...|..
GPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase wee.AA GCN2 487-517 29 0.000394 9.88 In-house 481-511 (511) Show / Hide 
Range on Protein: 487-517
Range on HMM: 481-511/511
Sequence Identity: 29% (9 aa)

SRDFNELIAQMMHPYPDKRPTSQSIFSHPIL
..|....|...  . |.|||. |..  |. |
HKDQQDMIRWCLNHDPQKRPSAQQLLQHEFL
Kinase wee.AA NEK 239-269 30 0.000591 10.27 In-house 1-36 (286) Show / Hide 
Range on Protein: 239-269
Range on HMM: 1-36/286
Sequence Identity: 30% (11 aa)

FMQVNVIGVGEFGVVFQCVNRLDGCI-----YAIKK
.  . .|| | ||.|. .  . || .     |..||
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKK
Kinase wee.AA Pkinase_Tyr 239-362 21 0.000695 13.78 Pfam 1-137 (270) Show / Hide 
Range on Protein: 239-362
Range on HMM: 1-137/270
Sequence Identity: 21% (30 aa)

FMQVNVIGVGEFGVVFQCVNR----LDGCIYAIKKSKKPVAGSS--FEKRALNEVWAHAVLGKHDNVVRYYSAWA-EDDH--MLIQNEFCDGGSLHARIQ
     ..| |.||.|.... .     ...  |.|.  |. | ..  . .  ..|.     ||.|.|.||.| .   ....  ..|  |.. .|.|.   .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

DH-----CLGEAELKIVLMHVIEGLRYIHSNDLVHMDL
.|      |   .|    . . .|. | .|. ..| ||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL
Kinase wee.AA SLK 487-517 19 0.001872 7.38 In-house 229-259 (259) Show / Hide 
Range on Protein: 487-517
Range on HMM: 229-259/259
Sequence Identity: 19% (6 aa)

SRDFNELIAQMMHPYPDKRPTSQSIFSHPIL
|..|.... . ..  |..|.|.. .. |. .
SKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase wee.AA Ciliate-E2-Unclassified 489-517 36 0.001885 7.86 In-house 323-352 (352) Show / Hide 
Range on Protein: 489-517
Range on HMM: 323-352/352
Sequence Identity: 36% (11 aa)

DFNE-LIAQMMHPYPDKRPTSQSIFSHPIL
|| . |. .|.   |.||.| . |. ||..
DFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase wee.AA Ciliate-E2-Unclassified 435-458 40 0.003 7.15 In-house 236-262 (352) Show / Hide 
Range on Protein: 435-458
Range on HMM: 236-262/352
Sequence Identity: 40% (11 aa)

EILHE-DYSNL--FKADIFSLGITLFE
|.| .  |..   .|.||.|||. |.|
EVLQGQNYDHSKAYKCDIWSLGVILYE
Kinase wee.AA SLK 445-464 65 0.006069 5.63 In-house 181-200 (259) Show / Hide 
Range on Protein: 445-464
Range on HMM: 181-200/259
Sequence Identity: 65% (13 aa)

FKADIFSLGITLFEAAGGGP
.||||.|||||| | | . |
YKADIWSLGITLIEMAQMEP
Kinase wee.AA PEK 446-458 61 0.013778 3.08 In-house 684-696 (758) Show / Hide 
Range on Protein: 446-458
Range on HMM: 684-696/758
Sequence Identity: 61% (8 aa)

KADIFSLGITLFE
| ||.|||. .||
KVDIYSLGLIFFE
Kinase wee.AA PEK 446-458 61 0.031583 2.68 In-house 574-586 (655) Show / Hide 
Range on Protein: 446-458
Range on HMM: 574-586/655
Sequence Identity: 61% (8 aa)

KADIFSLGITLFE
|.|..|||| .||
KVDMYSLGIIFFE
Kinase wee.AA GCN2 446-458 57 0.045026 2.55 In-house 432-445 (511) Show / Hide 
Range on Protein: 446-458
Range on HMM: 432-445/511
Sequence Identity: 57% (8 aa)

KADIFSL-GITLFE
|.|..|| || .||
KVDMYSLGGIIFFE
Kinase wee.AA CAMK 472-517 18 0.099919 0.53 In-house 356-425 (425) Show / Hide 
Range on Protein: 472-517
Range on HMM: 356-425/425
Sequence Identity: 18% (13 aa)

WHNLRDGKVP-ILPSLSR-----------------------DFNELIAQMMHPYPDKRPTSQSIFSHPIL
... . ||   . | .|                        .   || .|. . |.||.| . . .|| .
FEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM